SL 0101-1

By Targets:	Antibiotic (6) Bacterial (5) Drug Intermediate (1) Fluorescent Dye (2) Fungal (6) Isotope-Labeled Compounds (2) MicroRNA (4) Reference Standards (2) Ribosomal S6 Kinase (RSK) (1) Small Interfering RNA (siRNA) (1) TGF-beta/Smad (1) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (10) Infection (6) Inflammation/Immunology (2)
Oligonucleotides:	miRNA mimics (1) miRNA antagomirs (1) miRNA agomirs (1) MicroRNAs (4) miRNA inhibitors (1) Human Pre-designed siRNA Sets (1) siRNAs (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15237

SL 0101-1 5+ Cited Publications SL0101	Ribosomal S6 Kinase (RSK)	Cancer
SL 0101-1 (SL0101), a kaempferol glycoside, isolated from the tropical plant F. refracta, is a cell-permeable, selective, reversible, ATP-competitive p90 Ribosomal S6 Kinase (RSK) inhibitor, with an IC₅₀ of 89 nM . SL 0101-1 (SL0101) is a selective RSK1/2 inhibitor, with a K_i of 1 μM .

HY-N0101

Neohesperidin 5+ Cited Publications Hesperetin 7-O-neohesperidoside	β-catenin Wnt	Inflammation/Immunology
Neohesperidin is a flavonoid compound abundant in citrus plants with antioxidant and anti-inflammatory effects. Neohesperidin can upregulate the Wnt/β-catenin signaling pathway, enhance the nuclear translocation of β-catenin and the differentiation of bone marrow stromal cells .

HY-I0101

4-tert-Butylcalix[4]arene Tetra-tert-butyl(tetrahydroxy)calix[4]arene	Drug Intermediate	Others
4-tert-Butylcalix[4]arene (Tetra-tert-butyl(tetrahydroxy)calix[4]arene) is a drug intermediate for synthesis of various active compounds.

HY-RI01011A

hsa-miR-4327 antagomir	MicroRNA	Cancer
hsa-miR-4327 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-4327 antagomir hsa-miR-4327 antagomir

HY-R01011A

hsa-miR-4327 agomir	MicroRNA	Cancer
hsa-miR-4327 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-4327 agomir hsa-miR-4327 agomir

HY-B0101B

Fluconazole mesylate UK 49858 mesylate	Fungal Antibiotic Bacterial	Infection Cancer
Fluconazole (mesylate) is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.

HY-D0101

Fluorescein-diphosphat diammonium	Fluorescent Dye
Fluorescein-diphosphat (diammonium) is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.

HY-B0101A

Fluconazole hydrate UK 49858 hydrate	Fungal Antibiotic Bacterial	Infection Cancer
Fluconazole (hydrate) is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.

HY-RS01011

ARNT Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ARNT Human Pre-designed siRNA Set A contains three designed siRNAs for ARNT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ARNT Human Pre-designed siRNA Set A ARNT Human Pre-designed siRNA Set A

HY-B0101S1

Fluconazole-13C2,15N UK-49858-¹³C₂,¹⁵N	Isotope-Labeled Compounds Fungal Antibiotic Bacterial	Infection Cancer
Fluconazole-13C2,15N (UK-49858-13C2,15N) is the ¹³C and ¹⁵N labeled isotope of Fluconazole (HY-B0101). Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC₉₉s range from 0.20 μg/mL to 0.39 μg/mL .

HY-R01011

hsa-miR-4327 mimic	MicroRNA	Cancer
hsa-miR-4327 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-4327 mimic hsa-miR-4327 mimic

HY-B0101R

Fluconazole (Standard) UK-49858 (Standard)	Reference Standards Fungal Antibiotic Bacterial	Infection Cancer
Fluconazole (Standard) is the analytical standard of Fluconazole. This product is intended for research and analytical applications. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .

HY-D0101A

Fluorescein-diphosphat ammonium	Fluorescent Dye	Others
Fluorescein-diphosphat (ammonium) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

HY-B0101

Fluconazole Maximum Cited Publications 16 Publications Verification UK-49858	Fungal Antibiotic Bacterial	Infection Cancer
Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC₉₉s range from 0.20 μg/mL to 0.39 μg/mL .

HY-N0101R

Neohesperidin (Standard) Hesperetin 7-O-neohesperidoside (Standard)	TGF-beta/Smad Reference Standards	Inflammation/Immunology
Neohesperidin (Standard) is the analytical standard of Neohesperidin. This product is intended for research and analytical applications. Neohesperidin is a flavonoid compound found in high amounts in citrus fruits with anti-oxidant and anti-inflammatory effects.

HY-B0101S

Fluconazole-d4 UK-49858-d₄	Isotope-Labeled Compounds Fungal Antibiotic	Infection
Fluconazole-d₄ is the deuterium labeled Fluconazole. Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .

HY-RI01011

hsa-miR-4327 inhibitor	MicroRNA	Cancer
hsa-miR-4327 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-4327 inhibitor hsa-miR-4327 inhibitor

Cat. No.	Product Name

HY-L0101V

FCH Group Screening Library	2,244,487 compounds
FCH Group Screening Library Collection contains about 2,244,487 lead-like compounds for biological screening. This brand new collection comprises polar molecules with pharmacologically important groups such as free carboxylic and amino groups.

Cat. No.	Product Name	Type

HY-D0101A

Fluorescein-diphosphat ammonium	Fluorescent Dyes/Probes
Fluorescein-diphosphat (ammonium) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

Fluorescein-diphosphat ammonium

Fluorescent Dyes/Probes

Fluorescein-diphosphat (ammonium) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.