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SKLB-Y13

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-176848
    SKLB-Y13

    		YTHDF Apoptosis Cancer
    SKLB-Y13 is a selective YTHDF1 inhibitor with an IC50 of 0.76  μM. SKLB-Y13 binds to the m 6A recognition pocket and disrupts m 6A-dependent YTHDF1-PRPF6 mRNA interaction, impairing the translation of PRPF6 and inhibiting breast cancer proliferation while promoting apoptosis. SKLB-Y13 has antitumor activity, promising for cancers therapies targeting RNA epigenetic Readers .
    SKLB-Y13

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