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Results for "

Retinol

" in MedChemExpress (MCE) Product Catalog:

32

Inhibitors & Agonists

11

Natural
Products

14

Recombinant Proteins

5

Isotope-Labeled Compounds

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0679
    Retinyl acetate
    2 Publications Verification

    Retinol acetate; Vitamin A acetate

    Others Cancer
    Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities .
    Retinyl acetate
  • HY-B1384

    Vitamin A palmitate; Retinol palmitate

    Endogenous Metabolite Others
    Retinyl palmitate is an ester of Retinol and is the major form of vitamin A found in the epidermis. Retinyl palmitate has been widely used in pharmaceutical and cosmetic formulations.
    Retinyl palmitate
  • HY-N0679S4

    Retinol acetate-d4; Vitamin A acetate-d4

    Isotope-Labeled Compounds Cancer
    Retinyl acetate-d4 is the deuterium labeled Retinyl acetate . Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities .
    Retinyl acetate-d4
  • HY-W654334

    Isotope-Labeled Compounds Endogenous Metabolite Inflammation/Immunology
    9-cis-Retinol-d5 is deuterium labeled 9-cis Retinol. 9-cis Retinol is a precursor of 9-cis-Retinal (HY-W009310). 9-cis Retinol can inhibit 9-cis-Retinoic acid (HY-15128) synthesis in Hep G2 cells .
    9-cis-Retinol-d5
  • HY-W587806

    Endogenous Metabolite Inflammation/Immunology
    9-cis Retinol is a precursor of 9-cis-Retinal (HY-W009310). 9-cis Retinol can inhibit 9-cis-Retinoic acid (HY-15128) synthesis in Hep G2 cells .
    9-cis Retinol
  • HY-N0679S

    ALK-001; Retinol acetate-d3; Vitamin A acetate-d3

    Isotope-Labeled Compounds Metabolic Disease
    Retinyl acetate-d3 (ALK-001) is a deuterated Vitamin A. Retinyl acetate-d3 can be used for research of geographic atrophy (GA) secondary to age-related macular degeneration (AMD) .
    Retinyl acetate-d3
  • HY-W587807

    Endogenous Metabolite Neurological Disease
    11-cis-Retinol, a form of retinol, can bind to RDH5. 11-cis-Retinol promote dark adaptation and recovery of photoresponsiveness of red cones but not of red rods .
    11-cis-Retinol
  • HY-169085

    Acyltransferase Metabolic Disease
    LRAT-IN-1 (compound 1) is a retinol acyltransferase (LRAT) inhibitor (IC50=21.1 μM). LRAT-IN-1 provides anti-aging effects by inhibiting the esterification of retinol to form retinol esters, increasing the available retinol in the skin. Research on LRAT-IN-1 as an anti-aging ingredient in cosmetics .
    LRAT-IN-1
  • HY-142107S

    Isotope-Labeled Compounds Others
    9-cis,13-cis-Retinol-d5 is the deuterium labeled 9-cis,13-cis-Retinol .
    9-cis,13-cis-Retinol-d5
  • HY-16760

    9-cis-Vitamin A acetate; ZuRetinol acetate

    Others Others
    9-cis-Retinol acetate is a retinal derivative.
    9-cis-Retinol acetate
  • HY-N7495R

    Anhydrovitamin A (Standard)

    Reference Standards Drug Metabolite Metabolic Disease
    all-trans-Anhydro Retinol (Standard) (Anhydrovitamin A (Standard)) is the analytical standard of all-trans-Anhydro Retinol (HY-N7495). This product is intended for research and analytical applications. all-trans-Anhydro Retinol (Anhydrovitamin A) is an orally active degradation product formed by the dehydration of vitamin A alcohol and its esters under conditions such as acidic catalysis or hydroxylic solvents, with a biological activity only 0.4% of that of Vitamin A (HY-B1342). In rats, all-trans-Anhydro Retinol can be metabolized into hydroxy derivatives and their esters, but it cannot be converted into Vitamin A (HY-B1342) and has a low storage capacity in the body .
    all-trans-Anhydro Retinol (Standard)
  • HY-N7495

    Anhydrovitamin A

    Drug Metabolite Metabolic Disease
    all-trans-Anhydro Retinol (Anhydrovitamin A) is an orally active degradation product formed by the dehydration of vitamin A alcohol and its esters under conditions such as acidic catalysis or hydroxylic solvents, with a biological activity only 0.4% of that of Vitamin A (HY-B1342). In rats, all-trans-Anhydro Retinol can be metabolized into hydroxy derivatives and their esters, but it cannot be converted into Vitamin A (HY-B1342) and has a low storage capacity in the body .
    all-trans-Anhydro Retinol
  • HY-147251

    Drug Derivative Others
    SRI 6409-94 is an orally active Ro 13-6298 analogue that is teratogenic. SRI 6409-94 serves as a molecular tool to study the effect of the three-dimensional configuration of retinol on teratogenic activity .
    SRI 6409-94
  • HY-172232

    Lipocalin Family Neurological Disease
    STG-001 is a retinol binding protein 4 (RBP4) antagonist. STG-001 inhibits RBP4 to reduce the synthesis of retinal and diretinol, thereby preventing photoreceptor degeneration. STG-001 can be used in the study of sexually precocious nephropathy (STGD) .
    STG-001
  • HY-16760S

    9-cis-Vitamin A acetate-d5; ZuRetinol acetate-d5

    Isotope-Labeled Compounds Others
    9-cis-Retinol acetate-d5 is the deuterium labeled 9-cis-Retinol acetate. 9-cis-Retinol acetate is a retinal derivative .
    9-cis-Retinol acetate-d5
  • HY-B1342R

    Vitamin A1 (Standard); all-trans-Retinol (Standard)

    Endogenous Metabolite Metabolic Disease
    Vitamin A (Standard) is the analytical standard of Vitamin A. This product is intended for research and analytical applications. Retinol is an endogenous metabolite.
    Vitamin A (Standard)
  • HY-145806

    13-cis-Retinol acetate; 13-cis-Vitamin A acetate

    Endogenous Metabolite Endocrinology
    13-cis-Retinyl acetate (13-cis-Retinol acetate; 13-cis-Vitamin A acetate) is a 13-cis isomer formed by Retinyl acetate. 13-cis-Retinyl acetate is an active metabolite of vitamin A .
    13-cis-Retinyl acetate
  • HY-W739769

    13,14-DihydroRetinol

    Endogenous Metabolite Others
    all-trans-13,14-Dihydroretinol is a metabolite of all-trans-retinol (HY-B1342). all-trans-retinol is catalyzed by retinol saturase to form all-trans-13,14-Dihydroretinol .
    all-trans-13,14-Dihydroretinol
  • HY-139394

    Lipocalin Family Metabolic Disease
    Arachidonoyl-1-thio-glycerol (Compound 5) is an nonretinoid ligand lipid that can interact with cellular retinol binding protein 2 (CRBP2) .
    Arachidonoyl-1-thio-glycerol
  • HY-N0679R

    Others Cancer
    Retinyl acetate (Standard) is the analytical standard of Retinyl acetate. This product is intended for research and analytical applications. Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities .
    Retinyl acetate (Standard)
  • HY-115731

    Desmethyltocopherol; DL-Tocol; rac-Tocol

    Endogenous Metabolite Metabolic Disease
    (±)-Tocol is a synthetic vitamin E derivative.nlike (±)-α-tocopherol, (±)-tocol does not suppress retinol-induced erythrocyte hemolysis or increase microviscosity of rat liver phosphatidylcholine (PC) liposomes.
    Tocol
  • HY-107633
    A 1120
    1 Publications Verification

    Transthyretin (TTR) Metabolic Disease
    A 1120 is a high-affinity nonretinoid retinol-binding protein 4 (RBP4) antagonist with a Ki value of 8.3 nM. A 1120 disrupts the interaction between RBP4 and its binding partner transthyretin .
    A 1120
  • HY-B1342

    Vitamin A1; all-trans-Retinol

    Endogenous Metabolite Metabolic Disease
    Vitamin A (Vitamin A1) is an endogenous metabolite.
    Vitamin A
  • HY-19720

    ACU-4429

    RPE65 Metabolic Disease
    Emixustat is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. Emixustat is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) .
    Emixustat
  • HY-W011094
    Win 18446
    1 Publications Verification

    Aldehyde Dehydrogenase (ALDH) Endocrinology
    Win 18446 is an orally active testes-specific enzyme ALDH1a2 inhibitor, with an IC50 of 0.3 μM. Win 18446 reversibly inhibits spermatogenesis in many species and inhibits Retinoic acid (HY-14649) biosynthesis from Retinol (HY-B1342) within the testes .
    Win 18446
  • HY-19720A

    ACU-4429 hydrochloride

    Others Metabolic Disease
    Emixustat (ACU-4429) hydrochloride is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. Emixustat hydrochloride is also a visual cycle modulator, capable of regulating visual cycle activity by inhibiting retinol isomerization, and holds potential for studying vision disorders such as age-related macular degeneration (AMD) .
    Emixustat hydrochloride
  • HY-147366

    Lipocalin Family Metabolic Disease
    RBP4 ligand-1 is a non-retinoid ligands for (RBP4) retinol-binding protein 4. The hRBP4SPA IC50 and RBP4-TTR FRET IC50 values are 0.23±0.11 and 0.13±0.12 μM in the radioligand binding assay and FRET assay, respectively .
    RBP4 ligand-1
  • HY-B1342A

    13-cis-Vitamin A1; 13-cis-Retinol

    Drug Isomer Drug Metabolite Metabolic Disease
    13-cis-Vitamin A (13-cis-Vitamin A1) is the 13-cis-isomer of Vitamin A (HY-B1342), which is an active metabolite found in butter .
    13-cis-Vitamin A
  • HY-143793

    Lipocalin Family Metabolic Disease
    RBP4 inhibitor 1 (compound 43b) is a potent and orally active retinol-binding protein 4 (RBP4) inhibitor with IC50s of 28 nM and 110 nM for human and mouse RBP4. RBP4 inhibitor 1 has a potent and long-lasting blood RBP4-level-reducing effect in mice .
    RBP4 inhibitor 1
  • HY-W004500
    All-trans-retinal
    1 Publications Verification

    Endogenous Metabolite Apoptosis Metabolic Disease
    All-trans-retinal is an vitamin A metabolite in the retina, and is produced following photo-isomerization of the visual chromophore 11-cis-Retinal. All-trans-retinal is cleared from photoreceptors by ATP-binding cassette transporter (ABCA4) and all-trans-retinol dehydrogenase (RDH). All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis .
    All-trans-retinal
  • HY-W009310

    Endogenous Metabolite Organoid Others
    9-cis-Retinal is a natural retinoid. Dietary 9-cis-β-carotene generates 9-cis-retinoids via cleavage into 9-cis-retinal. 9-cis Retinal binds to cellular retinol-binding protein-I (CRBP-I) and CRBP-II with Kds of 8 nM and 5 nM, respectively. 9-cis-Retinal expedites differentiation and maturation of rod photoreceptors in retinal organoids .
    9-cis-Retinal
  • HY-125904

    RAR/RXR Neurological Disease Inflammation/Immunology Cancer
    4-Hydroxyretinoic acid (4-HRA) is a naturally occurring retinoid derivative with diverse biological effects. 4-Hydroxyretinoic acid is formed from retinol catalyzed by cytochrome P-450 isozyme(s), and is mainly metabolized by the liver in the body. 4-Hydroxyretinoic acid also serves as the substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7. 4-Hydroxyretinoic acid regulates gene expression and cell differentiation via binding to nuclear receptor RAR (Retinoic Acid Receptor), and activates RARs and RXR-alpha, to induce cancer cell apoptosis. In addition, 4-Hydroxyretinoic acid is also involved in various physiological processes such as immune regulation, neuroprotection, and anti-oxidation .
    4-Hydroxyretinoic acid

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