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Recombinant Ten-Eleven Translocase

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  • HY-E70583
    Recombinant Ten-Eleven Translocase

    		TET Protein Others
    Recombinant Ten-Eleven Translocase is a recombinant Fe(II)- and α-ketoglutarate-dependent dioxygenase. Recombinant Ten-Eleven Translocase converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), and then to 5-formylcytosine (5fC) and 5-carboxycytosine (5caC) through a series of oxidation reactions. Then, 5caC is further converted into uracil (U) through the action of a conversion agent or enzyme, and uracil (U) is converted into thymine (T) through PCR, thereby achieving single-base resolution and high-accuracy identification of DNA methylation sites .
    Recombinant Ten-Eleven Translocase

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