Search Result
Results for "
Reactive aldehydes
" in MedChemExpress (MCE) Product Catalog:
33
Biochemical Assay Reagents
1
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-135136
-
-
-
- HY-D1667
-
|
|
Fluorescent Dye
|
Others
|
|
BDP 558/568 hydrazide is a carbonyl reactive hydrazide derivative of BDP 558/568 (BDP 558/568: Ex=558 nm, Em=568 nm). BDP 558/568 hydrazide can be used for the labeling of aldehydes or ketones.
|
-
-
- HY-157916
-
|
Aldehyde Reactive probe
|
Fluorescent Dye
|
Others
|
|
ARP (Aldehyde reactive probe) is an aldehyde reactive probe for detecting abasic site (common DNA lesions and intermediates in mutagenesis and carcinogenesis) in DNA, which specificially tags AP site with biotin residues. ARP is highly sensitive with a femtomolar-level basic site detection capabilities (less than one site per 10 4 nucleotides) .
|
-
-
- HY-W015012
-
|
|
Fluorescent Dye
|
Others
|
|
NBD-Hydrazine is an aldehyde- and ketone-reactive fluorescent probe. NBD-Hydrazine has excitation/emission maxima of 468/535 nm in the presence of aldehydes or ketones. NBD-Hydrazine can be used as a starting material to synthesize malondialdehyde-reactive fluorescent probes. NBD-Hydrazine is a synthetic intermediate in the synthesis of cupric and chronic ion colorimetric sensors .
|
-
-
- HY-W586329
-
|
|
Ligands for E3 Ligase
|
Others
|
|
Thalidomide-4-carbaldehyde is a Thalidomide analogue with an aldehyde. Thalidomide recruiits E3 ligase for the ubiquitinylation and subsequent proteolysis of target proteins. The aldehyde is highly reactive towards amine nucleophiles through reductive amination among other reactions.
|
-
-
- HY-W451211
-
|
|
Ligands for E3 Ligase
|
Cancer
|
|
Thalidomide-5-carbaldehyde is a Thalidomide analogue with an aldehyde. Thalidomide recruiits E3 ligase for the ubiquitinylation and subsequent proteolysis of target proteins. The aldehyde is highly reactive towards amine nucleophiles through reductive amination among other reactions.
|
-
-
- HY-W800649
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Aminooxy-PEG2-amine hydrochloride (compound L3) is an aqueous soluble crosslinker. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond, if a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term .
|
-
-
- HY-174948B
-
|
NHS-PEG-Aldehyde (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
NHS-PEG-CHO (MW 3400) (NHS-PEG-Aldehyde (MW 3400)) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
-
- HY-174948
-
|
NHS-PEG-Aldehyde (MW 1000)
|
Biochemical Assay Reagents
|
Others
|
|
NHS-PEG-CHO (MW 1000) (NHS-PEG-Aldehyde (MW 1000)) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
-
- HY-174948A
-
|
NHS-PEG-Aldehyde (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
|
NHS-PEG-CHO (MW 2000) (NHS-PEG-Aldehyde (MW 2000)) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
-
- HY-174948C
-
|
NHS-PEG-Aldehyde (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
|
NHS-PEG-CHO (MW 5000) (NHS-PEG-Aldehyde (MW 5000)) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
-
- HY-W143230
-
|
4-Benzyloxybutanal
|
Biochemical Assay Reagents
|
Others
|
|
4-(Benzyloxy)butanal (4-Benzyloxybutanal) is a linker with an acid labile, benzyl protecting group and a reactive primary aldehyde. The primary aldehyde can react with hydrazide and aminooxy groups which are commonly used in biomolecular probes for labeling and crosslinking carbonyls (oxidized carbohydrates).
|
-
-
- HY-W190918
-
|
|
Biochemical Assay Reagents
|
Others
|
|
endo-BCN-PEG4-amine is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
-
- HY-W793100
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Endo-BCN-PEG2-Biotin is a PEG linker containing a BCN group and a terminal carboxylic acid. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
-
- HY-W590588
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Diethyl acetal-PEG4-amine is a PEG reagent containing an amino (NH2) group and a terminal diethyl acetal protecting group, which can be deprotected to form the free aldehyde. NH2 group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
|
-
-
- HY-W591965
-
|
|
Biochemical Assay Reagents
|
Others
|
|
t-Boc-Aminooxy-pentane-amine is a linker containing an aminooxy group and a primary amine. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
-
- HY-W012971
-
|
|
Biochemical Assay Reagents
|
Others
|
|
5-Amino-1-pentanol is a linker containing a hydroxyl group and amine group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
-
- HY-W800650
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Aminooxy-PEG1-amine is a chemical reagent containing an aminooxy group and a primary amine. The aminooxy group is reactive with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive withactivated NHS esters, or carboxylic acid in the presence of coupling reagent EDC. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term.
|
-
-
- HY-W879032
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Endo-BCN-PEG4-Pomalidomide is a PEG derivative composed of BCN, PEG4 and Pomalidomide (HY-10984). The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
-
- HY-W998707
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA amine, 5-isomer hydrochloride is a rhodamine dye with excitation/emission maximum 553/575 nm. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
-
- HY-W153502
-
|
|
Biochemical Assay Reagents
|
Others
|
|
MeNH-PEG2-OH is a PEG linker containing a hydroxyl group with a methylamine group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The methylamine group is reactive with carboxylic acids, carbonyls (ketone, aldehyde) etc.
|
-
-
- HY-W879044
-
|
Endo-BCN-PEG15-NH2
|
Biochemical Assay Reagents
|
Others
|
|
Endo-BCN-PEG15-amine (Endo-BCN-PEG15-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
-
- HY-W879025
-
|
Endo-BCN-PEG8-NH2
|
Biochemical Assay Reagents
|
Others
|
|
Endo-BCN-PEG8-amine (Endo-BCN-PEG8-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
-
- HY-W879045
-
|
Endo-BCN-PEG5-NH2
|
Biochemical Assay Reagents
|
Others
|
|
Endo-BCN-PEG5-amine (Endo-BCN-PEG5-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
-
- HY-W585386
-
|
|
Fluorescent Dye
|
Others
|
|
BDP TMR amine hydrochloride is a BDP dye linker is very bright which makes it useful for processes such as determining quantum yield. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
-
- HY-172284
-
|
|
Fluorescent Dye
|
Others
|
|
6-TAMRA cadaverine has achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
|
-
-
- HY-W190915
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4,7,10,13,16–Pentaoxanonadecane-1,19-diamine is a PEG based linker with two terminal amine groups. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
-
- HY-176509D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-CHO (MW 10000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 10000) can be used for drug delivery .
|
-
-
- HY-176509B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-CHO (MW 3400) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 3400) can be used for drug delivery .
|
-
-
- HY-176509C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-CHO (MW 5000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 5000) can be used for drug delivery .
|
-
-
- HY-176509
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-CHO (MW 1000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 1000) can be used for drug delivery .
|
-
-
- HY-176509E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-CHO (MW 20000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 20000) can be used for drug delivery .
|
-
-
- HY-176509H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-CHO (MW 40000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 40000) can be used for drug delivery .
|
-
-
- HY-176509A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-CHO (MW 2000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 2000) can be used for drug delivery .
|
-
-
- HY-W591379
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Amino-PEG19-amine is a PEG linker containing two amine functional groups. The hydrophilic PEG spacer increases solubility in aqueous media. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
|
-
-
- HY-W154175
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Boc-DODA is a linker containing a Boc-protected amino group and a terminal amine. The Boc group can be deprotected under mild acidic conditions to form the free amine. The terminal amine is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
-
- HY-W590569
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Azido-PEG12-amine is a water soluble PEG compound. The azide group enables Click Chemistry. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The hydrophilic PEG arm increases solubility in aqueous media.
|
-
-
- HY-161794
-
|
|
FKBP
|
Cancer
|
|
SP3N is a specific degrader of the prolyl isomerase FKBP12. The alkylamine of SP3N is metabolized to a reactive aldehyde (SP3CHO), which recruits the SCFFBXO22 ligase for FKBP12 degradation. SP3N may be used in research for cancer .
|
-
-
- HY-161794A
-
|
|
FKBP
|
Cancer
|
|
SP3N hydrochloride is a specific degrader of the prolyl isomerase (FKBP12). The alkylamine of SP3N hydrochloride is metabolized to a reactive aldehyde (SP3CHO), which recruits the SCF FBXO22 ligase for FKBP12 degradation. SP3N hydrochloride may be used in research for cancer .
|
-
-
- HY-121252
-
|
|
α-synuclein
|
Neurological Disease
|
|
Dopal is an aldehyde that can be generated in Parkinson's disease by enzymatic degradation of dopamine. Dopal can generate reactive oxygen species (ROS), and triggers aggregation of α-synuclein. Dopal elicits α-synuclein accumulation and hampers α-synuclein clearance in primary neurons .
|
-
-
- HY-W479025
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Fmoc-DODA hydrochloride is a linker with an Fmoc-protected amine and a terminal amine group. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
-
- HY-114351
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY FL Hydrazide is a green-fluorescent dye, BODIPY FL Hydrazide is reactive with aldehyde/ketone on polysaccharides and glycoproteins, yielding a reversible Schiff base product that can be transformed to a stable linkage using a reducing agent like sodium borohydride or sodium cyanoborohydride. (λex=495 nm, λem=516 nm) .
|
-
-
- HY-N3149
-
|
|
STAT
Apoptosis
Reactive Oxygen Species (ROS)
|
Cancer
|
|
(E)-2-Hydroxycinnamaldehyde is an aldehyde that can be separated from the stem bark of cinnamon. (E)-2-Hydroxycinnamaldehyde inhibits cell proliferation and induces apoptosis by inhibiting signal transduction of STAT3 and reactive oxygen species production. (E)-2-Hydroxycinnamaldehyde has antitumor activity .
|
-
-
- HY-W092344
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1,5-Bis-Boc-1,5,9-triazanonane is a linker containing two Boc-protected amino groups and a terminal amine. The Boc groups can be deprotected under mild acidic conditions to form the free amines. The terminal amine is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
-
- HY-42213
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N1,N4-Bis-Boc-spermidine is a linker containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
-
- HY-42222
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N1,N5-Bis-Boc-spermidine is a linker containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
-
- HY-WAA0302
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1,4-Bis-Boc-1,4,7-triazaheptane is a PEG derivative containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
-
- HY-W800654
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG5-amine is a PEG linker containing a maleimide group and an amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
-
- HY-W440884
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-Ald, MW 3400 is a self-assemble polyPEG which spontaneously forms lipid bilayer in water. The polymer can be used to prepare nanoparticles or liposomse as a targeted drug carrier, such as mRNA vaccine. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
-
-
- HY-W190922
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG4-amine is a PEG linker containing a maleimide group and an amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-23629
-
|
|
PROTAC Linkers
|
Cancer
|
|
16-Aminohexadecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. 16-Aminohexadecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
|
-
- HY-121252A
-
|
|
α-synuclein
|
Neurological Disease
|
|
Dopal (purity>80%) is an aldehyde that can be generated in Parkinson's disease by enzymatic degradation of dopamine. Dopal (purity>80%) can generate reactive oxygen species (ROS), and triggers aggregation of α-synuclein. Dopal (purity>80%) elicits α-synuclein accumulation and hampers α-synuclein clearance in primary neurons .
|
-
- HY-W401143
-
|
|
PROTAC Linkers
|
Cancer
|
|
15-Aminopentadecanoic Acid can be used as a PROTAC linker in the synthesis of PROTACs. 15-Aminopentadecanoic Acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
|
-
- HY-W101722
-
|
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl (9-aminononyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-W1049075A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-pALD (MW 5000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-pALD (MW 20000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-pALD (MW 10000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-pALD (MW 2000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-pALD (MW 40000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-pALD (MW 3400) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W105727
-
|
|
PROTAC Linkers
|
Cancer
|
|
9-Aminononanoic acid can be used as a PROTAC linker and other conjugation in the synthesis of PROTACs. 9-Aminononanoic acid is an alkane chain with terminal carboxlic acid and amine groups. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
|
-
- HY-W1049075
-
|
|
Biochemical Assay Reagents
|
Others
|
|
mPEG-pALD (MW 1000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W105744
-
|
|
PROTAC Linkers
|
Cancer
|
|
10-Aminodecanoic acid is an alkane chain with terminal carboxlic acid and amine groups. 10-Aminodecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond.
|
-
- HY-W440883
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Ald, MW 2000 is a phospholipid polyPEG which can self-assemble to form lipid bilayer in aqueous solution. The polymer can be used to prepare liposome as a drug delivery vehicle for administration of drugs or nutrients, such as mRNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
-
- HY-141147
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
7-O-(Amino-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Amino-PEG4)-paclitaxel can be used in the synthesis of Antibody-Drug Conjugates (ADCs) .
|
-
- HY-W712314
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG-amine (MW 5000) is a PEG Linker. The reactive primary amine or NH2 rapidly react with aldehyde, ketone to form imine. Imine upon further reduction forms secondary amine via reductive amination. Amine reacts with activated carboxyl acid, NHS ester to form stable amide bonds. 4-Arm PEG reagents are useful crosslinking reagent and used for drug delivery .
|
-
- HY-B1018A
-
|
|
Monoamine Oxidase
GABA Receptor
Histone Demethylase
|
Cardiovascular Disease
Neurological Disease
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Phenelzine sulfate, an antidepressant agent, is an irreversible and orally active monoamine oxidase (MAO-A and MAO-B) inhibitor. Phenelzine sulfate inhibits GABA transaminase and primary amine oxidase (PrAO), and sequester reactive aldehydes. Phenelzine sulfate also inhibits LSD1 (Ki: 5.6 μM) and suppresses oxidative stress and lipogenesis. Phenelzine sulfate elevates neurotransmitters (serotonin, norepinephrine, dopamine). Phenelzine sulfate is studied in neurological, metabolic and cancer diseases for depression and anxiety disorders, stroke, spinal cord injury, traumatic brain injury, multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, inflammatory pain, obesity and prostate cancer .
|
-
- HY-141148
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
7-O-(Cbz-N-amido-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Cbz-N-amido-PEG4)-paclitaxel can be used in the synthesis of Antibody-Drug Conjugates (ADCs) .
|
-
- HY-W131541
-
|
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl (11-aminoundecyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. tert-Butyl (11-aminoundecyl)carbamate can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-W440885
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG-Ald, MW 5000 is a phospholipid PEG polymer which can self-assemble spontaneously in water with their hydrophilic heads oriented toward the water (micelles). The polymer can be used to prepare liposome as a drug nanocarrier for administration of nutrients and therapeutic drugs, such as lipid nanoparticles in mRNA or DNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
-
- HY-W1048547A
-
|
HOOC-PEG-Amine (MW 2000)
|
Biochemical Assay Reagents
|
Others
|
|
HOOC-PEG-NH2 (MW 2000) (HOOC-PEG-Amine (MW 2000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547J
-
|
HOOC-PEG-Amine (MW 40000)
|
Biochemical Assay Reagents
|
Others
|
|
HOOC-PEG-NH2 (MW 40000) (HOOC-PEG-Amine (MW 40000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W190905
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N4, N9-di-Boc-spermine is a spermine linker containing two a Boc-protected amino groups and two amine groups. The Boc groups can be deprotected under mild acidic conditions to form the free amine. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Spermidine is a polyamine that modulates various cellular activities like cellular development and differentiation, stability of DNA, and apoptosis.
|
-
- HY-W1048547H
-
|
HOOC-PEG-Amine (MW 1000)
|
Biochemical Assay Reagents
|
Others
|
|
HOOC-PEG-NH2 (MW 1000) (HOOC-PEG-Amine (MW 1000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547E
-
|
HOOC-PEG-Amine (MW 20000)
|
Biochemical Assay Reagents
|
Others
|
|
HOOC-PEG-NH2 (MW 20000) (HOOC-PEG-Amine (MW 20000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547I
-
|
HOOC-PEG-Amine (MW 3400)
|
Biochemical Assay Reagents
|
Others
|
|
HOOC-PEG-NH2 (MW 3400) (HOOC-PEG-Amine (MW 3400)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547C
-
|
HOOC-PEG-Amine (MW 5000)
|
Biochemical Assay Reagents
|
Others
|
|
HOOC-PEG-NH2 (MW 5000) (HOOC-PEG-Amine (MW 5000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W348348
-
|
|
Biochemical Assay Reagents
|
Others
|
|
CbzNH-PEG3-CH2CH2NH2 is a PEG linker containing an amine group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
|
-
- HY-42773
-
|
1-Boc-1,8-diaminooctane
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl (8-aminooctyl)carbamate (1-Boc-1,8-diaminooctane) can be used as a PROTAC linker in the synthesis of PROTACs. tert-butyl (8-aminooctyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-W1048547D
-
|
HOOC-PEG-Amine (MW 10000)
|
Biochemical Assay Reagents
|
Others
|
|
HOOC-PEG-NH2 (MW 10000) (HOOC-PEG-Amine (MW 10000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W047688
-
|
1-Boc-1,10-diaminodecane
|
PROTAC Linkers
|
Cancer
|
|
tert-Butyl (10-aminodecyl)carbamate (1-Boc-1,10-diaminodecane) can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. tert-Butyl (10-aminodecyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
|
-
- HY-W800618
-
|
|
ADC Linker
|
Others
|
|
NH2-PEG3-Val-Cit-PAB-OH is a cleavable ADC linker featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.
|
-
- HY-W800617
-
|
|
ADC Linker
|
Cancer
|
|
NH2-PEG1-Val-Cit-PAB-OH is a cleavable ADC linker intermediate featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.
|
-
- HY-W800619
-
|
|
ADC Linker
|
Others
|
|
NH2-PEG4-Val-Cit-PAB-OH is a cleavable ADC linker featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.
|
-
- HY-W800620
-
|
|
ADC Linker
|
Others
|
|
NH2-PEG6-Val-Cit-PAB-OH is a cleavable ADC linker featuring a primary amine, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB group. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The primary amine is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses such as in SNAr reactions or heterocyclic chemistry. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery via an elimination mechanism within the PAB structure.
|
-
- HY-125372
-
|
ABAO
|
Biochemical Assay Reagents
|
Others
|
|
2-Amino benzamidoxime (ABAO compound 6) can react quickly with aldehydes to form stable 1, 2-dihydroquinazoline 3-oxides in aqueous solutions. The 2-Amino benzamidoxime reaction process consists of the formation of a Schiff base as a rate-determining step, followed by rapid intramolecular cyclization. The reaction rate is dependent on pH, indicating that protonated benzamidoxime is involved in the formation of Schiff bases as an internal generalized acid. Substituents on the aromatic ring can increase the alkalinity of the aromatic amine, thus speeding up the reaction. The reactive properties of 2-Amino benzamidoxime make it a potential platform for the development of new bioconjugated strategies, fluorescent probes, and post-translational diversification of genetic coding libraries .
|
-
- HY-B1018AS
-
|
|
Isotope-Labeled Compounds
Monoamine Oxidase
GABA Receptor
Histone Demethylase
|
Cardiovascular Disease
Neurological Disease
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Phenelzine-d5 sulfate is the deuterium labeled Phenelzine sulfate (HY-B1018A). Phenelzine sulfate, an antidepressant agent, is an irreversible and orally active monoamine oxidase (MAO-A and MAO-B) inhibitor. Phenelzine sulfate inhibits GABA transaminase and primary amine oxidase (PrAO), and sequester reactive aldehydes. Phenelzine sulfate also inhibits LSD1 (Ki: 5.6 μM) and suppresses oxidative stress and lipogenesis. Phenelzine sulfate elevates neurotransmitters (serotonin, norepinephrine, dopamine). Phenelzine sulfate is studied in neurological, metabolic and cancer diseases for depression and anxiety disorders, stroke, spinal cord injury, traumatic brain injury, multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, inflammatory pain, obesity and prostate cancer .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-114351
-
|
|
Fluorescent Dyes/Probes
|
|
BODIPY FL Hydrazide is a green-fluorescent dye, BODIPY FL Hydrazide is reactive with aldehyde/ketone on polysaccharides and glycoproteins, yielding a reversible Schiff base product that can be transformed to a stable linkage using a reducing agent like sodium borohydride or sodium cyanoborohydride. (λex=495 nm, λem=516 nm) .
|
-
- HY-D1667
-
|
|
Fluorescent Dyes/Probes
|
|
BDP 558/568 hydrazide is a carbonyl reactive hydrazide derivative of BDP 558/568 (BDP 558/568: Ex=558 nm, Em=568 nm). BDP 558/568 hydrazide can be used for the labeling of aldehydes or ketones.
|
-
- HY-W998707
-
|
|
Fluorescent Dyes/Probes
|
|
TAMRA amine, 5-isomer hydrochloride is a rhodamine dye with excitation/emission maximum 553/575 nm. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
- HY-172284
-
|
|
Fluorescent Dyes/Probes
|
|
6-TAMRA cadaverine has achieved prominence as a dye for oligonucleotide labeling and automated DNA sequencing applications. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc.
|
| Cat. No. |
Product Name |
Type |
-
- HY-157916
-
|
Aldehyde Reactive probe
|
Indicators
|
|
ARP (Aldehyde reactive probe) is an aldehyde reactive probe for detecting abasic site (common DNA lesions and intermediates in mutagenesis and carcinogenesis) in DNA, which specificially tags AP site with biotin residues. ARP is highly sensitive with a femtomolar-level basic site detection capabilities (less than one site per 10 4 nucleotides) .
|
-
- HY-174948B
-
|
NHS-PEG-Aldehyde (MW 3400)
|
Drug Delivery
|
|
NHS-PEG-CHO (MW 3400) (NHS-PEG-Aldehyde (MW 3400)) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
- HY-174948
-
|
NHS-PEG-Aldehyde (MW 1000)
|
Drug Delivery
|
|
NHS-PEG-CHO (MW 1000) (NHS-PEG-Aldehyde (MW 1000)) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
- HY-174948A
-
|
NHS-PEG-Aldehyde (MW 2000)
|
Drug Delivery
|
|
NHS-PEG-CHO (MW 2000) (NHS-PEG-Aldehyde (MW 2000)) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
- HY-174948C
-
|
NHS-PEG-Aldehyde (MW 5000)
|
Drug Delivery
|
|
NHS-PEG-CHO (MW 5000) (NHS-PEG-Aldehyde (MW 5000)) is a PEG derivative consisting of an aldehyde group (-CHO), a PEG unit, and an NHS ester. NHS esters can be conjugated to amino acids or other molecules containing amino groups. Aldehyde groups are reactive functional groups that can react with compounds containing amino or hydroxyl groups .
|
-
- HY-W793100
-
|
|
Drug Delivery
|
|
Endo-BCN-PEG2-Biotin is a PEG linker containing a BCN group and a terminal carboxylic acid. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
|
-
- HY-W879032
-
|
|
Drug Delivery
|
|
Endo-BCN-PEG4-Pomalidomide is a PEG derivative composed of BCN, PEG4 and Pomalidomide (HY-10984). The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
- HY-W879044
-
|
Endo-BCN-PEG15-NH2
|
Drug Delivery
|
|
Endo-BCN-PEG15-amine (Endo-BCN-PEG15-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
- HY-W879025
-
|
Endo-BCN-PEG8-NH2
|
Drug Delivery
|
|
Endo-BCN-PEG8-amine (Endo-BCN-PEG8-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
- HY-W879045
-
|
Endo-BCN-PEG5-NH2
|
Drug Delivery
|
|
Endo-BCN-PEG5-amine (Endo-BCN-PEG5-NH2) is a click chemistry crosslinker reagent. The BCN groupis very reactive with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc .
|
-
- HY-176509D
-
|
|
Drug Delivery
|
|
DSPE-PEG-CHO (MW 10000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 10000) can be used for drug delivery .
|
-
- HY-176509B
-
|
|
Drug Delivery
|
|
DSPE-PEG-CHO (MW 3400) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 3400) can be used for drug delivery .
|
-
- HY-176509C
-
|
|
Drug Delivery
|
|
DSPE-PEG-CHO (MW 5000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 5000) can be used for drug delivery .
|
-
- HY-176509
-
|
|
Drug Delivery
|
|
DSPE-PEG-CHO (MW 1000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 1000) can be used for drug delivery .
|
-
- HY-176509E
-
|
|
Drug Delivery
|
|
DSPE-PEG-CHO (MW 20000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 20000) can be used for drug delivery .
|
-
- HY-176509H
-
|
|
Drug Delivery
|
|
DSPE-PEG-CHO (MW 40000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 40000) can be used for drug delivery .
|
-
- HY-176509A
-
|
|
Drug Delivery
|
|
DSPE-PEG-CHO (MW 2000) is a linear heterobifunctional PEGylation reagent with DSPE phospholipids and aldehyde groups. PEG linkers have good hydrophilicity and water solubility. Aldehyde-polyethylene glycol (DSPE) is one of the most commonly used reactive phospholipids to bind antibodies, peptides or other ligands to the surface of liposomes and other lipid-polyethylene glycol nanoparticles. DSPE-PEG-CHO (MW 2000) can be used for drug delivery .
|
-
- HY-W440884
-
|
|
Drug Delivery
|
|
DSPE-PEG-Ald, MW 3400 is a self-assemble polyPEG which spontaneously forms lipid bilayer in water. The polymer can be used to prepare nanoparticles or liposomse as a targeted drug carrier, such as mRNA vaccine. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
-
- HY-W1049075A
-
|
|
Drug Delivery
|
|
mPEG-pALD (MW 5000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075C
-
|
|
Drug Delivery
|
|
mPEG-pALD (MW 20000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075B
-
|
|
Drug Delivery
|
|
mPEG-pALD (MW 10000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075E
-
|
|
Drug Delivery
|
|
mPEG-pALD (MW 2000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075D
-
|
|
Drug Delivery
|
|
mPEG-pALD (MW 40000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075H
-
|
|
Drug Delivery
|
|
mPEG-pALD (MW 3400) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W1049075
-
|
|
Drug Delivery
|
|
mPEG-pALD (MW 1000) is an important unilaterally active PEG derivative whose reactive groups can react with amines, peptides and the N-termini of proteins to form imines containing C=N double bonds, which can be further reduced. Polyethylene glycol aldehyde or ketone derivatives can be used for reversible PEGylation by reacting with hydrazine or hydrazine to form hydrolyzed acylhydrazone bonds .
|
-
- HY-W440885
-
|
|
Drug Delivery
|
|
DSPE-PEG-Ald, MW 5000 is a phospholipid PEG polymer which can self-assemble spontaneously in water with their hydrophilic heads oriented toward the water (micelles). The polymer can be used to prepare liposome as a drug nanocarrier for administration of nutrients and therapeutic drugs, such as lipid nanoparticles in mRNA or DNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
-
- HY-W1048547A
-
|
HOOC-PEG-Amine (MW 2000)
|
Drug Delivery
|
|
HOOC-PEG-NH2 (MW 2000) (HOOC-PEG-Amine (MW 2000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547J
-
|
HOOC-PEG-Amine (MW 40000)
|
Drug Delivery
|
|
HOOC-PEG-NH2 (MW 40000) (HOOC-PEG-Amine (MW 40000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547H
-
|
HOOC-PEG-Amine (MW 1000)
|
Drug Delivery
|
|
HOOC-PEG-NH2 (MW 1000) (HOOC-PEG-Amine (MW 1000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547E
-
|
HOOC-PEG-Amine (MW 20000)
|
Drug Delivery
|
|
HOOC-PEG-NH2 (MW 20000) (HOOC-PEG-Amine (MW 20000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547I
-
|
HOOC-PEG-Amine (MW 3400)
|
Drug Delivery
|
|
HOOC-PEG-NH2 (MW 3400) (HOOC-PEG-Amine (MW 3400)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547C
-
|
HOOC-PEG-Amine (MW 5000)
|
Drug Delivery
|
|
HOOC-PEG-NH2 (MW 5000) (HOOC-PEG-Amine (MW 5000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
-
- HY-W1048547D
-
|
HOOC-PEG-Amine (MW 10000)
|
Drug Delivery
|
|
HOOC-PEG-NH2 (MW 10000) (HOOC-PEG-Amine (MW 10000)) is a heterobifunctional PEG crosslinker that can be used to attach functional PEG to biomolecules, particles, and other surface materials. The carboxyl group reacts with the amine group to form a stable amide bond. It can also react with the hydroxyl group to form an unstable ester bond. On the other hand, the amine group can be used to react with many amine-reactive groups, such as succinimidyl NHS esters, aldehydes, etc .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-B1018AS
-
|
|
|
Phenelzine-d5 sulfate is the deuterium labeled Phenelzine sulfate (HY-B1018A). Phenelzine sulfate, an antidepressant agent, is an irreversible and orally active monoamine oxidase (MAO-A and MAO-B) inhibitor. Phenelzine sulfate inhibits GABA transaminase and primary amine oxidase (PrAO), and sequester reactive aldehydes. Phenelzine sulfate also inhibits LSD1 (Ki: 5.6 μM) and suppresses oxidative stress and lipogenesis. Phenelzine sulfate elevates neurotransmitters (serotonin, norepinephrine, dopamine). Phenelzine sulfate is studied in neurological, metabolic and cancer diseases for depression and anxiety disorders, stroke, spinal cord injury, traumatic brain injury, multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, inflammatory pain, obesity and prostate cancer .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-W590569
-
|
|
|
Azide
|
|
Azido-PEG12-amine is a water soluble PEG compound. The azide group enables Click Chemistry. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. The hydrophilic PEG arm increases solubility in aqueous media.
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-W440883
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG-Ald, MW 2000 is a phospholipid polyPEG which can self-assemble to form lipid bilayer in aqueous solution. The polymer can be used to prepare liposome as a drug delivery vehicle for administration of drugs or nutrients, such as mRNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
|
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent:
