Aldehyde reactive probe TFA

Cat. No.: HY-135136 Purity: 96.40%: Data Sheet
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SDS
Handling Instructions
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Aldehyde reactive probe (TFA) is a biotinylated reagent for the detection and quantification of AP sites in damaged DNA.

For research use only. We do not sell to patients.

Aldehyde reactive probe TFA Chemical Structure

CAS No. : 627090-10-2

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote
200 mg	Get quote

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Based on 1 publication(s) in Google Scholar

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Description

Aldehyde reactive probe (TFA) is a biotinylated reagent for the detection and quantification of AP sites in damaged DNA^[1].

Molecular Weight

445.41

Formula

C₁₄H₂₂F₃N₅O₆S

CAS No.

627090-10-2

Appearance

Solid

Color

White to off-white

SMILES

O=C(NNC(CON)=O)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O.O=C(O)C(F)(F)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL (56.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2451 mL	11.2256 mL	22.4512 mL
5 mM	0.4490 mL	2.2451 mL	4.4902 mL
10 mM	0.2245 mL	1.1226 mL	2.2451 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 96.40%

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Data Sheet (267 KB) SDS (252 KB)

COA (248 KB) HNMR (299 KB) LCMS (96 KB)

Handling Instructions (2659 KB)

References

[1]. Ayumi Asaeda, et al. Highly sensitive assay of DNA abasic sites in mammalian cells-optimization of the aldehyde reactive probe method. Analytica Chimica Acta 365 (1998) 35-41.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.2451 mL	11.2256 mL	22.4512 mL	56.1281 mL
	5 mM	0.4490 mL	2.2451 mL	4.4902 mL	11.2256 mL
	10 mM	0.2245 mL	1.1226 mL	2.2451 mL	5.6128 mL
	15 mM	0.1497 mL	0.7484 mL	1.4967 mL	3.7419 mL
	20 mM	0.1123 mL	0.5613 mL	1.1226 mL	2.8064 mL
	25 mM	0.0898 mL	0.4490 mL	0.8980 mL	2.2451 mL
	30 mM	0.0748 mL	0.3742 mL	0.7484 mL	1.8709 mL
	40 mM	0.0561 mL	0.2806 mL	0.5613 mL	1.4032 mL
	50 mM	0.0449 mL	0.2245 mL	0.4490 mL	1.1226 mL