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Results for "

Ral

" in MedChemExpress (MCE) Product Catalog:

By Targets:	COX (1) JNK (1) p38 MAPK (1) Ras (4) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (4) Inflammation/Immunology (1)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (2)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

RBC10	Ras	Cancer
RBC10 is an anti-cancer agent. RBC10 inhibits the binding of Ral to its effector RALBP1. RBC10 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines .

RBC6	Ras	Cancer
RBC6 is an inhibitor of GTPases RalA. RBC6 inhibits binding of Ral to its effector RALBP1. RBC6 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts, as well as anchorage-independent growth of human cancer celllines .

RBC8	Ras p38 MAPK JNK	Cancer
RBC8 is a selective and allosteric RALA and RALB inhibitor. RBC8 stabilizes the inactive GDP-bound state of Ral, preventing its activation. RBC8 promotes the phosphorylation of proteins related to the MAPK/JNK pathway. RBC8 has the activity of inhibiting tumor cell proliferation, migration and invasion. RBC8 is used in the study of various cancers such as lung cancer, gastric cancer, and multiple myeloma .

BQU57	Ras	Cancer
BQU57 is a selective inhibitor of RalA/RalB small GTPases, with a binding potency (Kb) of 7.7 μM for RalB-GDP. BQU57 can block its interaction with effector proteins (such as SEC5 and EXO84), inhibiting tumor cell migration, invasion and non-adherent growth. BQU57 downregulates the NF-κB signaling pathway, reduces the expression of IL-6, IL-8 and MMP-13, and inhibits apoptosis by regulating the Bcl-2/Bax balance. BQU57 also protects the extracellular matrix by inhibiting the *Ral/NF-κB* pathway and can be used for the study of degenerative diseases. BQU57 exhibits significant antitumor activity in triple-negative breast cancer (TNBC) models, inhibiting orthotopic tumor growth and lung metastasis and enhancing paclitaxel chemotherapy sensitivity .

RALA Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
RALA Human Pre-designed siRNA Set A contains three designed siRNAs for RALA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

RALA Human Pre-designed siRNA Set A RALA Human Pre-designed siRNA Set A

Rala Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Rala Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rala gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Rala Mouse Pre-designed siRNA Set A Rala Mouse Pre-designed siRNA Set A

AL-8417 (2R)-AL-5898	COX	Inflammation/Immunology
AL-8417 ((2R)-AL-5898) is a potent inhibitor of Cyclooxygenase (COX), with IC₅₀ of 120 μM, that plays an important role in inflammatory response .

Cat. No.	Compare	Product Name	Application	Reactivity

	RAP1 Antibody (YA1824) Ras-related protein Rap-1b; K-REV; Ral1B	WB, IP	Human, Mouse, Rat
	RAP1 Antibody (YA1824) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RAP1.

	RALA Antibody (YA3752) Ral	WB, IHC-P, ICC/IF, FC, ELISA	Human, Mouse, Rat, Monkey
	RALA Antibody (YA3752) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RALA.

	RALB Antibody (YA1816) Ras-related protein Ral-B	WB, IP	Human, Mouse
	RALB Antibody (YA1816) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RALB.

	RAP1A + RAP1B Antibody (YA6741) C21KG antibody; G 22K antibody; G-22K antibody; GTP binding protein smg p21A antibody; GTP-binding protein smg p21A antibody; KREV 1 antibody; KREV1 antibody; OTTHUMP00000013741 antibody; RAP 1A antibody; RAP1 antibody; C21KG antibody; G 22K antibody; G-22K antibody; GTP binding protein smg p21A antibody; GTP-binding protein smg p21A antibody; KREV 1 antibody; KREV1 antibody; OTTHUMP00000013741 antibody; RAP 1A antibody; RAP1 antibody; RAP1A antibody; RAP1A member of RAS oncogene family antibody; RAP1A_HUMAN antibody; Ras related protein Krev 1 antibody; Ras related protein Rap 1A antibody; RAS related protein RAP1A antibody; Ras-related protein Krev-1 antibody; Ras-related protein Rap-1A antibody; SMGP21 antibody; GTP-binding protein smg p21B antibody; K-REV antibody; OK/SW-cl.11 antibody; Ral1B antibody; rap1b antibody; RAP1B member of RAS oncogene family antibody; RAP1B_HUMAN antibody; Ras family small GTP binding protein RAP1B antibody; RAS related protein RAP1B antibody; Ras-related protein Rap-1b antibody; Small GTP binding protein antibody;	WB, FC	Human, Mouse
	RAP1A + RAP1B Antibody (YA6741) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RAP1A + RAP1B.

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RALA Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
RALA Human Pre-designed siRNA Set A contains three designed siRNAs for RALA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Rala Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Rala Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rala gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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