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Results for "

RM-1

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

2

Inhibitory Antibodies

1

Natural
Products

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12486
    FL118
    2 Publications Verification

    10,11-(Methylenedioxy)-20(S)-camptothecin

    		 Survivin Apoptosis IAP Cancer
    FL118 (10,11-(Methylenedioxy)-20(S)-camptothecin), a Camptothecin (HY-16560) analogue, is a potent and orally active survivin inhibitor. FL118 binds to oncoprotein DDX5 (p68) to dephosphorylates and degrades DDX5. FL118 can be used for the research of cancer [1] .
    FL118
  • HY-121793
    Roemerine

    (-)-Roemerine

    		 Endogenous Metabolite 5-HT Receptor mGluR iGluR Bacterial Antibiotic Infection Neurological Disease Cancer
    Roemerine is an alkaloid that has been identified from the leaves of Fibraurea recisa Pierre. Roemerine exhibits antibacterial, anticancer, and antidepressant activities, can reverse the multidrug resistance phenotype in cultured cells, and exerts antibacterial effects by regulating the cAMP signaling pathway. Additionally, Roemerine influences neuronal activity by increasing BDNF protein expression and modulating the serotonergic and glutamatergic systems. Roemerine holds promise for research in the fields of cancer, infections, and neurological diseases [1] .
    Roemerine
  • HY-162264
    Tubulin polymerization/V-ATPase-IN-1

    		Microtubule/Tubulin Proton Pump Apoptosis Inflammation/Immunology Cancer
    Tubulin polymerization/V-ATPase-IN-1 (compound F10) is a Tubulin polymerization/V-ATPase inhibitor. Tubulin polymerization/V-ATPase-IN-1 shows robust antiproliferation activity against four human cancer cell lines, and exerts antiproliferative activity by inhibiting tubulin and V-ATPase. Tubulin polymerization/V-ATPase-IN-1 induces immunogenic cell death in addition to apoptosis, and inhibits tumor growth in an RM-1 homograft model with enhanced T lymphocyte infiltration [1].
    Tubulin polymerization/V-ATPase-IN-1
  • HY-P991243
    MP-RM-1

    		EGFR PI3K Akt Cancer
    MP-RM-1 is a selective murine monoclonal antibody inhibitor targeting human epidermal growth factor receptor 3 (ErbB-3). MP-RM-1 blocks the activation of ErbB-3 induced by neuregulin 1 (NRG-1β) and promotes the internalization and degradation of ErbB-3, inhibiting downstream signaling pathways such as PI3K-Akt. MP-RM-1 is promising for research of ErbB-3 highly expressed solid tumors such as breast cancer, melanoma, and prostate cancer [1].
    MP-RM-1
  • HY-RS14548
    Tiparp Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) PARP Others

    Tiparp Rat Pre-designed siRNA Set A contains three designed siRNAs for Tiparp gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Tiparp Rat Pre-designed siRNA Set A
    Tiparp Rat Pre-designed siRNA Set A
  • HY-P990265
    Anti-Mouse CD69 Antibody (CD69.2.2)

    		Transmembrane Glycoprotein Orthopoxvirus Infection Others Inflammation/Immunology Cancer
    Anti-Mouse CD69 Antibody (CD69.2.2) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to mouse CD69. Anti-Mouse CD69 Antibody (CD69.2.2) causes CD69 to be internalized but does not deplete CD69 + cells. Anti-Mouse CD69 Antibody (CD69.2.2) can be used for the researches of cancer, infection, inflammation and immunology, such as RMA-S tumor, arthritis and vaccinia virus (VACV) infection [1] .
    Anti-Mouse CD69 Antibody (CD69.2.2)

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