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Results for "

RCD

" in MedChemExpress (MCE) Product Catalog:

By Targets:	c-Fms (2) Complement System (1) Ferroptosis (1) Fungal (1) IGF-1R (2) Interleukin Related (1) Orexin Receptor (OX Receptor) (1) Parasite (1) RIP kinase (1)
By Research Areas:	Cancer (3) Cardiovascular Disease (2) Infection (1) Inflammation/Immunology (6) Metabolic Disease (3) Neurological Disease (2)

Inhibitors & Agonists

Screening Libraries

Inhibitory Antibodies

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990228

Anti-Mouse IL-10R/CD210 Antibody (1B1.3A)	Interleukin Related Parasite Fungal	Infection Metabolic Disease
Anti-Mouse IL-10R/CD210 Antibody (1B1.3A) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse *IL-10R/CD210. Anti-Mouse IL-10R/CD210* Antibody (1B1.3A) blocks of IL-10R signaling. Anti-Mouse IL-10R/CD210 Antibody (1B1.3A) can be used for the researches of cancer, infection and metabolic disease, such as diabetes and malaria .

HY-112063

CIL56 4 Publications Verification	Ferroptosis	Cancer
CIL56 is a potent and selective ferroptosis inducer. Ferroptosis is an iron-dependent form of regulated cell death (RCD).

HY-P990125

Anti-Mouse CSF1R/CD115 Antibody (AFS98)	c-Fms	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology
Anti-Mouse (CSF1R/CD115) Antibody (AFS98) is an anti-mouse CSF1R IgG2a antibody inhibitor derived from rats. Anti-Mouse (CSF1R/CD115) Antibody (AFS98) inhibits M-CSF-dependent colony formation and cell growth by blocking the binding of M-CSF to its receptor. Anti-Mouse (CSF1R/CD115) Antibody (AFS98) can be used for the researches of inflammation, metabolic disease, cardiovascular disease and neurological disease, such as such as stroke, diabetes and arthritis .

HY-151369

AV123	RIP kinase	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology
AV123 (compound 12) is a non-cytotoxic RIPK1 inhibitor (IC₅₀=12.12 µM). AV123 blocks the TNF-α-induced necroptotic (EC₅₀=1.7 μM) but not the apoptotic cell death. AV123 can be used in the study of necrotic chronic conditions such as ischemia-reperfusion injury of the brain, heart and kidney, inflammatory diseases, neurodegenerative diseases and infectious diseases .

HY-174257

RCD405	Others	Inflammation/Immunology
RCD405 is a bronchodilator. RCD405 exerts relaxant effects by acting directly on human airway smooth muscle (hASM) with an EC₅₀ value of 12 μM for histamine-induced contractions and 45.71 μM for carbachol-induced contractions. RCD405 inhibits cholinergic and histaminergic tone and reduces electrically stimulated (EFS)-induced contractions. RCD405 is promising for research of asthma and chronic obstructive pulmonary disease (COPD) .

HY-P990479

Anti-OX2R/CD200R1 Antibody	Orexin Receptor (OX Receptor)	Inflammation/Immunology
Anti-OX2R/CD200R1 Antibody is a CHO-expressed human antibody that targets *OX2R/CD200R1. The predicted molecular weight (MW) of Anti-OX2R/CD200R1* Antibody is 146.58 kDa. The isotype control for Anti-OX2R/CD200R1 Antibody can refer to Human IgG4 kappa, Isotype Control (HY-P99003).

HY-P990849

Anti-CSF1R/CD115 Antibody (2-4A5-4)	c-Fms	Others
Anti-CSF1R/CD115 Antibody (2-4A5-4) is a kind of rat IgG1 κ chimeric antibody inhibitor, targeting to human *CSF1R/CD115. Anti-CSF1R/CD115* Antibody (2-4A5-4) can neutralize colony stimulating factor 1 receptor (CSF1R), also known as CD115. Anti-CSF1R/CD115 Antibody (2-4A5-4) can be used for the detections of immunohistochemistry, functional assays and flow cytometry .

HY-P991255

VRDN-002	IGF-1R	Inflammation/Immunology
VRDN-002 is a human monoclonal antibody (mAb) targeting *IGF1R/CD221*. VRDN-002 reduces inflammation and proptosis in thyroid eye disease (TED). VPI-2690B can be used in Graves ophthalmopathy research .

HY-P991329

ASP-1948	Complement System	Cancer
ASP-1948 is a human monoclonal antibody (mAb) targeting *NRP1/VEGF165R/CD34*. ASP-1948 reverses the suppressive effects of regulatory T cells. ASP-1948 can be used in solid tumors research .

HY-P991253

BIIB022	IGF-1R	Cancer
BIIB022 is a human IgG4 monoclonal antibody (mAb) targeting *IGF1R/CD221*. BIIB022 blocks IGF-1 and IGF-2-induced phosphorylation of IGF-1R and downstream substrates. BIIB022 can be used in lung, pancreatic, and colon cancer research. Recommended isotype control: Human IgG4 kappa, Isotype Control (HY-P99003) .

Cat. No.	Product Name

HY-L162

Cell Death Library	3,229 compounds
Cell death plays a crucial role in the development of the body and the maintenance of internal balance to prevent the development of diseases. According to the regulation of the involved processes, cell death can be defined as programmed and non-programmed death. Programmed cell death (PCD) can be divided into lytic cell death and nonlytic cell death, mainly including apoptosis, necrotic apoptosis and Pyroptosis. Non-Programmed cell death (Non-PCD) generally refers to necrosis. In stark contrast to Accidental Cell Death (ACD), Regulatory Cell Death (RCD) relies on specialized molecular mechanisms. Cell death includes internal apoptosis, external apoptosis, necrotic apoptosis, ferroptosis, pyroptosis, lysosome-dependent cell death, etc. MCE designs a unique collection of 3,229 cell death compounds, covering multiple targets, such as Apoptosis, Ferroptosis, Pyroptosis, Necroptosis, etc. It is a useful tool for screening cell death drugs.

Cell Death Library

3,229 compounds

Cell death plays a crucial role in the development of the body and the maintenance of internal balance to prevent the development of diseases. According to the regulation of the involved processes, cell death can be defined as programmed and non-programmed death. Programmed cell death (PCD) can be divided into lytic cell death and nonlytic cell death, mainly including apoptosis, necrotic apoptosis and Pyroptosis. Non-Programmed cell death (Non-PCD) generally refers to necrosis. In stark contrast to Accidental Cell Death (ACD), Regulatory Cell Death (RCD) relies on specialized molecular mechanisms. Cell death includes internal apoptosis, external apoptosis, necrotic apoptosis, ferroptosis, pyroptosis, lysosome-dependent cell death, etc.

MCE designs a unique collection of 3,229 cell death compounds, covering multiple targets, such as Apoptosis, Ferroptosis, Pyroptosis, Necroptosis, etc. It is a useful tool for screening cell death drugs.

Cat. No.	Product Name	Target	Research Area

HY-P990228

Anti-Mouse IL-10R/CD210 Antibody (1B1.3A)	Interleukin Related Parasite Fungal	Infection Metabolic Disease
Anti-Mouse IL-10R/CD210 Antibody (1B1.3A) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse *IL-10R/CD210. Anti-Mouse IL-10R/CD210* Antibody (1B1.3A) blocks of IL-10R signaling. Anti-Mouse IL-10R/CD210 Antibody (1B1.3A) can be used for the researches of cancer, infection and metabolic disease, such as diabetes and malaria .

HY-P990125

Anti-Mouse CSF1R/CD115 Antibody (AFS98)	c-Fms	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology
Anti-Mouse (CSF1R/CD115) Antibody (AFS98) is an anti-mouse CSF1R IgG2a antibody inhibitor derived from rats. Anti-Mouse (CSF1R/CD115) Antibody (AFS98) inhibits M-CSF-dependent colony formation and cell growth by blocking the binding of M-CSF to its receptor. Anti-Mouse (CSF1R/CD115) Antibody (AFS98) can be used for the researches of inflammation, metabolic disease, cardiovascular disease and neurological disease, such as such as stroke, diabetes and arthritis .

HY-P990440

Anti-IGF1R/CD221 Antibody	Inhibitory Antibodies	Inflammation/Immunology
Anti-IGF1R/CD221 Antibody is a CHO-expressed human antibody that targets *IGF1R/CD221. Anti-IGF1R/CD221* Antibody contains huIgG1 heavy chains and huκ light chains, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-IGF1R/CD221 Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990479

Anti-OX2R/CD200R1 Antibody	Orexin Receptor (OX Receptor)	Inflammation/Immunology
Anti-OX2R/CD200R1 Antibody is a CHO-expressed human antibody that targets *OX2R/CD200R1. The predicted molecular weight (MW) of Anti-OX2R/CD200R1* Antibody is 146.58 kDa. The isotype control for Anti-OX2R/CD200R1 Antibody can refer to Human IgG4 kappa, Isotype Control (HY-P99003).

HY-P990849

Anti-CSF1R/CD115 Antibody (2-4A5-4)	c-Fms	Others
Anti-CSF1R/CD115 Antibody (2-4A5-4) is a kind of rat IgG1 κ chimeric antibody inhibitor, targeting to human *CSF1R/CD115. Anti-CSF1R/CD115* Antibody (2-4A5-4) can neutralize colony stimulating factor 1 receptor (CSF1R), also known as CD115. Anti-CSF1R/CD115 Antibody (2-4A5-4) can be used for the detections of immunohistochemistry, functional assays and flow cytometry .

HY-P991255

VRDN-002	IGF-1R	Inflammation/Immunology
VRDN-002 is a human monoclonal antibody (mAb) targeting *IGF1R/CD221*. VRDN-002 reduces inflammation and proptosis in thyroid eye disease (TED). VPI-2690B can be used in Graves ophthalmopathy research .

HY-P991329

ASP-1948	Complement System	Cancer
ASP-1948 is a human monoclonal antibody (mAb) targeting *NRP1/VEGF165R/CD34*. ASP-1948 reverses the suppressive effects of regulatory T cells. ASP-1948 can be used in solid tumors research .

HY-P991253

BIIB022	IGF-1R	Cancer
BIIB022 is a human IgG4 monoclonal antibody (mAb) targeting *IGF1R/CD221*. BIIB022 blocks IGF-1 and IGF-2-induced phosphorylation of IGF-1R and downstream substrates. BIIB022 can be used in lung, pancreatic, and colon cancer research. Recommended isotype control: Human IgG4 kappa, Isotype Control (HY-P99003) .

Cat. No.	Compare	Product Name	Species	Source

HY-P703260

	CNOT9 Protein, Human (His, Strep) RCD1; RQCD1	Human	E. coli
	CNOT9 Protein, Human (His, Strep) is the recombinant human-derived CNOT9, expressed by E. coli , with Strep, His labeled tag.

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