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Puromycin

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By Targets:	Aminopeptidase (2) Antibiotic (10) Apoptosis (3) Bacterial (8) Biochemical Assay Reagents (2) Dipeptidyl Peptidase (2) Isotope-Labeled Compounds (2) MAP3K (1) NF-κB (1) Parasite (4) Proteasome (1) Reference Standards (3)
By Research Areas:	Cancer (3) Infection (7) Neurological Disease (1)
Click Chemistry:	Alkynes (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1743

*Puromycin* Maximum Cited Publications 265 Publications Verification CL13900	Bacterial Antibiotic Parasite	Infection
Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

HY-15695

Puromycin aminonucleoside 30+ Cited Publications NSC 3056	Bacterial Apoptosis Dipeptidyl Peptidase Aminopeptidase Antibiotic	Cancer
Puromycin aminonucleoside (NSC 3056) is the aminonucleoside portion of the antibiotic puromycin, and used in nephrosis animal models . Puromycin aminonucleoside induces apoptosis . Puromycin aminonucleoside is a reversible inhibitor of dipeptidyl peptidase II and cytosol alanyl aminopeptidase . Puromycin aminonucleoside induces secretion of cell migrasome .

HY-B1743S

Puromycin-d3 3 Publications Verification CL13900-d₃	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Puromycin-d₃ is the deuterium labeled Puromycin. Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

HY-B1743A

Puromycin dihydrochloride Maximum Cited Publications 265 Publications Verification CL13900 dihydrochloride	Bacterial Antibiotic Parasite	Infection Cancer
Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis .

HY-B1743AS

Puromycin-d3 dihydrochloride 3 Publications Verification CL13900-d₃ dihydrochloride	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Puromycin-d₃ (dihydrochloride) is the deuterium labeled Puromycin dihydrochloride. Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis .

HY-148865

Puromycin-bis(PEG2-amide)-Biotin	Biochemical Assay Reagents	Others
Puromycin-bis(PEG2-amide)-Biotin is a binding molecule. Puromycin-bis(PEG2-amide)-Biotin binds to the ribosome-RNA complex in cells. Puromycin-bis(PEG2-amide)-Biotin is used for single-cell translationome sequencing .

HY-15680

O-Propargyl-Puromycin 20+ Cited Publications	Biochemical Assay Reagents	Others
O-Propargyl-Puromycin, an alkyne analog of puromycin, is a potent protein synthesis inhibitor. O-Propargyl-Puromycin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B1743R

Puromycin (Standard) CL13900 (Standard)	Reference Standards Bacterial Antibiotic Parasite	Infection
Puromycin (Standard) is the analytical standard of Puromycin. This product is intended for research and analytical applications. Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

HY-B1743AR

Puromycin dihydrochloride (Standard) CL13900 dihydrochloride (Standard)	Reference Standards Bacterial Antibiotic Parasite	Infection
Puromycin (dihydrochloride) (Standard) is the analytical standard of Puromycin (dihydrochloride). This product is intended for research and analytical applications. Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis .

HY-15695R

Puromycin aminonucleoside (Standard) NSC 3056 (Standard)	Reference Standards Bacterial Apoptosis Dipeptidyl Peptidase Aminopeptidase Antibiotic	Cancer
Puromycin aminonucleoside (Standard) is the analytical standard of Puromycin aminonucleoside. This product is intended for research and analytical applications. Puromycin aminonucleoside (NSC 3056) is the aminonucleoside portion of the antibiotic puromycin, and used in nephrosis animal models[1]. Puromycin aminonucleoside induces apoptosis[2]. Puromycin aminonucleoside is a reversible inhibitor of dipeptidyl peptidase II and cytosol alanyl aminopeptidase[3]. Puromycin aminonucleoside induces secretion of cell migrasome[4].

HY-158410

PSA-IN-1	Others	Neurological Disease
PSA-IN-1 (compound 19) is a puromycin sensitive aminopeptidase (PSA) inhibitor with IC₅₀ at 7 nM. PSA-IN-1 has analgesic activity .

HY-110271

N-Acetylpuromycin	Antibiotic	Others
N-Acetylpuromycin is a inactive form of the antibiotic puromycin. N-Acetylpuromycin is the last intermediate of the puromycin antibiotic biosynthetic pathway in Streptomyces alboniger .

HY-119673

Lincophenicol	Antibiotic	Others
Lincophenicol is a hybrid antibiotic that has the activity of inhibiting the puromycin reaction catalyzed by Escherichia coli ribosomal peptidyl transferase and also inhibits the binding of specific compounds to the Escherichia coli ribosome.

HY-N15315

Triptriolide	Apoptosis MAP3K NF-κB	Others
Triptriolide inhibits Puromycin aminonucleoside PAN (HY-15695)-induced apoptosis in mouse podocytes through regulation of Bcl-2 family proteins and inhibition of Caspase-3. Triptriolide promotes the cell survival, protects and restores the podocyte function through activation of TAK1-NF-κB signaling pathway and upregulation of podocin .

HY-129407

AAF-CMK TFA Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase inhibitor II	Proteasome	Infection
AAF-CMK TFA (Ala-ala-phe-chloromethylketone tfa; N-Ala-Ala-Phe-CMK) is a subtilisin-type serine peptidase that removes tripeptides from the free NH2 termini of oligopeptides. AAF-CMK TFA is an irreversible inhibitor of TPPII and is typically used at concentrations of 10-100 μM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome. AAF-CMK also inhibits bleomycin hydrolase and puromycin-sensitive aminopeptidase when used at a concentration of 50 μM.

Cat. No.	Product Name

HY-K1057

Puromycin, Sterile 35+ Cited Publications
Puromycin is an aminonucleoside antibiotic produced by Streptomyces alboniger. It inhibits protein synthesis by disrupting peptide transfer on ribosomes, causing premature chain termination during translation. It can kill most gram-positive bacteria and various animal or insect cells.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1743

*Puromycin* 260+ Cited Publications CL13900	Infection Classification of Application Fields Disease Research Fields	Bacterial Antibiotic Parasite
Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

HY-B1743A

Puromycin dihydrochloride 260+ Cited Publications CL13900 dihydrochloride	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Resistance Selection Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Antibiotic Parasite
Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis .

HY-B1743AR

Puromycin dihydrochloride (Standard) CL13900 dihydrochloride (Standard)	Structural Classification Microorganisms Antibiotics Resistance Selection Source classification Antibacterial Disease Research Other Antibiotics	Reference Standards Bacterial Antibiotic Parasite
Puromycin (dihydrochloride) (Standard) is the analytical standard of Puromycin (dihydrochloride). This product is intended for research and analytical applications. Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis .

HY-N15315

Triptriolide	Triterpenes Structural Classification Terpenoids Source classification Celastraceae Tripterygium wilfordii Hook. f. Plants	Apoptosis MAP3K NF-κB
Triptriolide inhibits Puromycin aminonucleoside PAN (HY-15695)-induced apoptosis in mouse podocytes through regulation of Bcl-2 family proteins and inhibition of Caspase-3. Triptriolide promotes the cell survival, protects and restores the podocyte function through activation of TAK1-NF-κB signaling pathway and upregulation of podocin .

Cat. No.	Product Name	Chemical Structure

HY-B1743S

Puromycin-d3 3 Publications Verification
Puromycin-d₃ is the deuterium labeled Puromycin. Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

HY-B1743AS

Puromycin-d3 dihydrochloride 3 Publications Verification
Puromycin-d₃ (dihydrochloride) is the deuterium labeled Puromycin dihydrochloride. Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82414

	ERAP1 Antibody (YA2159) ERAP1; APPILS; ARTS1; KIAA0525; Endoplasmic reticulum aminopeptidase 1; ARTS-1; Adipocyte-derived leucine aminopeptidase; A-LAP; Aminopeptidase PILS; Puromycin-insensitive leucyl-specific aminopeptidase; PILS-AP; Type 1 tumor necrosis facto	WB, IHC-P	Human, Rat
	ERAP1 Antibody (YA2159) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2159), targeting ERAP1, with a predicted molecular weight of 107 kDa (observed band size: 107 kDa). ERAP1 Antibody (YA2159) can be used for WB, IHC-P experiment in human, rat background.

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HY-15680

O-Propargyl-Puromycin 20+ Cited Publications		Alkynes
O-Propargyl-Puromycin, an alkyne analog of puromycin, is a potent protein synthesis inhibitor. O-Propargyl-Puromycin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Puromycin

Inhibitors & Agonists

MCE Kits

NaturalProducts

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Natural
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