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Purine (Standard)

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29

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0091R
    Hypoxanthine (Standard)

    		Endogenous Metabolite Others
    Hypoxanthine (Standard) is the analytical standard of Hypoxanthine. This product is intended for research and analytical applications. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
    Hypoxanthine (Standard)
  • HY-W017389R
    Xanthine (Standard)

    		Endogenous Metabolite Inflammation/Immunology
    Xanthine (Standard) is the analytical standard of Xanthine. This product is intended for research and analytical applications. Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation . In Vitro: A number of stimulants are derived from Xanthine including caffeine and theobromine. Xanthine is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme.
    Xanthine (Standard)
  • HY-34431R
    Purine (Standard)

    7H-Imidazo(4,5-d)pyrimidine (Standard)

    		 Endogenous Metabolite Metabolic Disease
    Purine (Standard) is the analytical standard of Purine. This product is intended for research and analytical applications. Purine is an endogenous metabolite.
    Purine (Standard)
  • HY-112103R
    6-(γ,γ-Dimethylallylamino)purine (Standard)

    		Others Others
    6-(γ,γ-Dimethylallylamino)purine (Standard) is the analytical standard of 6-(γ,γ-Dimethylallylamino)purine. This product is intended for research and analytical applications. 6-(γ,γ-Dimethylallylamino)purine is a plant growth substance.
    6-(γ,γ-Dimethylallylamino)purine (Standard)
  • HY-13677R
    6-Mercaptopurine (Standard)

    		Nucleoside Antimetabolite/Analog Autophagy Endogenous Metabolite Cancer
    6-Mercaptopurine (Standard) is the analytical standard of 6-Mercaptopurine. This product is intended for research and analytical applications. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive drug.
    6-Mercaptopurine (Standard)
  • HY-13677AR
    6-Mercaptopurine hydrate (Standard)

    		Nucleoside Antimetabolite/Analog Cancer
    6-Mercaptopurine hydrate (Standard) is the analytical standard of 6-Mercaptopurine hydrate. This product is intended for research and analytical applications. 6-Mercaptopurine hydrate (Mercaptopurine hydrate; 6-MP hydrate) is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent.
    6-Mercaptopurine hydrate (Standard)
  • HY-106048R
    Bredinin aglycone (Standard)

    5-Hydroxy-1H-imidazole-4-carboxamide (Standard); FF-10501 (Standard)

    		 Nucleoside Antimetabolite/Analog Others
    Bredinin aglycone (Standard) is the analytical standard of Bredinin aglycone. This product is intended for research and analytical applications. Bredinin aglycone (5-Hydroxy-1H-imidazole-4-carboxamide) is a purine nucleotide analogue. Bredinin aglycone can be used to examine the efficiency of catalysts for the preparation of purine nucleotide analogues[1].
    Bredinin aglycone (Standard)
  • HY-103185R
    CCPA (Standard)

    2-Chloro-N6-cyclopentyladenosine (Standard)

    		 Nucleoside Antimetabolite/Analog Apoptosis Cancer
    CCPA (Standard) is the analytical standard of CCPA. This product is intended for research and analytical applications. CCPA (2-Chloro-N6-cyclopentyladenosine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    CCPA (Standard)
  • HY-154740R
    3′-Chloro-3′-deoxythymidine (Standard)

    		Nucleoside Antimetabolite/Analog Cancer
    3′-Chloro-3′-deoxythymidine (Standard) is the analytical standard of 3′-Chloro-3′-deoxythymidine. This product is intended for research and analytical applications. 3′-Chloro-3′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    3′-Chloro-3′-deoxythymidine (Standard)
  • HY-14268R
    Febuxostat (Standard)

    		Xanthine Oxidase Cardiovascular Disease Metabolic Disease
    Febuxostat (Standard) is the analytical standard of Febuxostat. This product is intended for research and analytical applications. Febuxostat (TEI 6720) is a potent, selective and non-purine xanthine oxidase (XO) inhibitor with a Ki value of 0.6 nM. Febuxostat has the potential for the research of hyperuricemia and gout .
    Febuxostat (Standard)
  • HY-W014993R
    1,3-Dimethyluric acid (Standard)

    		Drug Metabolite Endogenous Metabolite Others
    1,3-Dimethyluric acid (Standard) is the analytical standard of 1,3-Dimethyluric acid. This product is intended for research and analytical applications. 1,3-Dimethyluric acid is a product of theophylline metabolism in man. 1,3-Dimethyluric acid is one of the purine components in urinary calculi.
    1,3-Dimethyluric acid (Standard)
  • HY-W008638R
    2'-Deoxyinosine (Standard)

    		Endogenous Metabolite Metabolic Disease Cancer
    2'-Deoxyinosine (Standard) is the analytical standard of 2'-Deoxyinosine (HY-W008638). This product is intended for research and analytical applications. 2’-deoxyadenosine inhibits the growth of human colon-carcinoma cell lines and is found to be associated with purine nucleoside phosphorylase (PNP) deficiency.
    2'-Deoxyinosine (Standard)
  • HY-B0077R
    Bendamustine (hydrochloride) (Standard)

    		DNA Alkylator/Crosslinker Apoptosis Cancer
    Bendamustine (hydrochloride) (Standard) is the analytical standard of Bendamustine (hydrochloride). This product is intended for research and analytical applications. Bendamustine hydrochloride (SDX-105), a purine analogue, is a DNA cross-linking agent. Bendamustine hydrochloride activats DNA-damage stress response and apoptosis. Bendamustine hydrochloride has potent alkylating, anticancer and antimetabolite properties .
    Bendamustine (hydrochloride) (Standard)
  • HY-Y1055R
    Guanine (Standard)

    		DNA/RNA Synthesis Endogenous Metabolite Cancer
    Guanine (Standard) is the analytical standard of Guanine. This product is intended for research and analytical applications. Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool .
    Guanine (Standard)
  • HY-154779R
    5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine (Standard)

    		Nucleoside Antimetabolite/Analog Cancer
    5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine (Standard) is the analytical standard of 5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine. This product is intended for research and analytical applications. 5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    5′-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine (Standard)
  • HY-W017163R
    7-Methylxanthine (Standard)

    		Endogenous Metabolite Adenosine Receptor Metabolic Disease
    7-Methylxanthine (Standard) is the analytical standard of 7-Methylxanthine. This product is intended for research and analytical applications. 7-Methylxanthine is an orally active methyl derivative of xanthine and a non-selective adenosine receptor antagonist. 7-Methylxanthine is also one of the purine components of human urinary calculi. 7-Methylxanthine has anti-myopia activity .
    7-Methylxanthine (Standard)
  • HY-B0069R
    Fludarabine (Standard)

    F-ara-A (Standard); NSC 118218 (Standard)

    		 Nucleoside Antimetabolite/Analog DNA/RNA Synthesis STAT Apoptosis Cancer
    Fludarabine (Standard) is the analytical standard of Fludarabine. This product is intended for research and analytical applications. Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in lymphoproliferative malignancies. Fludarabine inhibits the cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in normal resting or activated lymphocytes .
    Fludarabine (Standard)
  • HY-B0152AR
    Adenine hydrochloride (Standard)

    6-AminoPurine hydrochloride (Standard); Vitamin B4 hydrochloride (Standard)

    		 DNA/RNA Synthesis Endogenous Metabolite Cancer
    Adenine (hydrochloride) (Standard) is the analytical standard of Adenine (hydrochloride). This product is intended for research and analytical applications. Adenine hydrochloride (6-Aminopurine hydrochloride), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hydrochloride acts as a chemical component of DNA and RNA. Adenine hydrochloride also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis[1][2][3].
    Adenine hydrochloride (Standard)
  • HY-113468R
    3-O-Methyl-DL-DOPA (Standard)

    		Endogenous Metabolite Neurological Disease
    3-O-Methyl-DL-DOPA (Standard) is the analytical standard of 3-O-Methyl-DL-DOPA. This product is intended for research and analytical applications. 3-O-Methyl-DL-DOPA is an endogenous metabolite present in Cerebrospinal_Fluid that can be used for the research of Epilepsy, Purine Nucleoside Phosphorylase Deficiency and Aromatic L Amino Acid Decarboxylase Deficiency [4].
    3-O-Methyl-DL-DOPA (Standard)
  • HY-103396R
    Trimetrexate glucuronate (Standard)

    CI-898 glucuronate (Standard)

    		 Antifolate Bacterial Infection Cancer
    Trimetrexate (glucuronate) (Standard) is the analytical standard of Trimetrexate (glucuronate). This product is intended for research and analytical applications. Trimetrexate glucuronate (NSC 352122) is a folic acid antagonist. Trimetrexate glucuronate affects DNA and RNA synthesis by inhibiting dihydrofolate reductase and preventing the synthesis of purine nucleotides and thymidylate. Trimetrexate glucuronate has potential antitumour activity and can also be used to inhibit Pneumocystis carinii pneumonia .
    Trimetrexate glucuronate (Standard)
  • HY-B0152R
    Adenine (Standard)

    6-AminoPurine (Standard); Vitamin B4 (Standard)

    		 DNA/RNA Synthesis Endogenous Metabolite Cancer
    Adenine (Standard) is the analytical standard of Adenine. This product is intended for research and analytical applications. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .
    Adenine (Standard)
  • HY-B0199R
    Mycophenolate Mofetil (Standard)

    RS 61443 (Standard); TM-MMF (Standard)

    		 Drug Metabolite Apoptosis Endogenous Metabolite Bacterial Cancer
    Mycophenolate Mofetil (Standard) is the analytical standard of Mycophenolate Mofetil. This product is intended for research and analytical applications. Mycophenolate mofetil (RS 61443) is the morpholinoethylester proagent of Mycophenolic acid. Mycophenolate mofetil inhibits de novo purine synthesis via the inhibition of inosine monophosphate dehydrogenase (IMPDH). Mycophenolate mofetil shows selective lymphocyte antiproliferative effects involve both T and B cells, preventing antibody formation .
    Mycophenolate Mofetil (Standard)
  • HY-41461R
    5-Amino-3H-imidazole-4-Carboxamide (Standard)

    		Endogenous Metabolite Others
    5-Amino-3H-imidazole-4-Carboxamide (Standard) is the analytical standard of 5-Amino-3H-imidazole-4-Carboxamide. This product is intended for research and analytical applications. 5-Amino-3H-imidazole-4-Carboxamide (AICA) is an important precursor for the synthesis of purines in general and of the nucleobases adenine and guanine in particular.
    5-Amino-3H-imidazole-4-Carboxamide (Standard)
  • HY-13599R
    Cladribine (Standard)

    		Adenosine Deaminase Apoptosis Cardiovascular Disease Cancer
    Cladribine (Standard) is the analytical standard of Cladribine. This product is intended for research and analytical applications. Cladribine (2-Chloro-2′-deoxyadenosine), a purine nucleoside analog, is an orally active adenosine deaminase inhibitor. Cladribine functions as an inhibitor of DNA synthesis to block the repair of the damaged DNA. Cladribine can inhibit DNA methylation. Cladribine has anti-lymphoma activity. Cladribine can be used for the research of several hematologic malignancies and multiple sclerosis .
    Cladribine (Standard)
  • HY-17563R
    2'-Deoxyguanosine (Standard)

    		Endogenous Metabolite Cancer
    2'-Deoxyguanosine (Standard) is the analytical standard of 2'-Deoxyguanosine. This product is intended for research and analytical applications. 2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells . In Vitro: 2'-Deoxyguanosine inhibits the clonal growth of HL-60 and K562 leukemia cells with IC50 values of 50 and 80 μM, respectively .
    2'-Deoxyguanosine (Standard)
  • HY-W011012R
    Adenosine 5'-monophosphate (disodium) (Standard)

    		Adenosine Receptor Metabolic Disease
    Adenosine 5'-monophosphate (disodium) (Standard) is the analytical standard of Adenosine 5'-monophosphate (disodium). This product is intended for research and analytical applications. Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes .
    Adenosine 5'-monophosphate (disodium) (Standard)
  • HY-135359R
    RP 48497 (Standard)

    		Drug Metabolite Neurological Disease
    Adenosine 5'-monophosphate (disodium) (Standard) is the analytical standard of Adenosine 5'-monophosphate (disodium). This product is intended for research and analytical applications. Adenosine 5'-monophosphate disodium is an orally active purine nucleotide, and participates in ATP metabolism. Adenosine 5'-monophosphate disodium is also a ligand for adenosine 2B receptor. Adenosine 5'-monophosphate disodium can activate AMPK in skeletal muscle, and ameliorates insulin resistance and impaired glucose metabolism. Adenosine 5'-monophosphate disodium can be used for research of diabetes .
    RP 48497 (Standard)
  • HY-N0097R
    Guanosine (Standard)

    		HSV Endogenous Metabolite Infection
    Guanosine (Standard) is the analytical standard of Guanosine. This product is intended for research and analytical applications. Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity. In Vitro: Guanosine can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP), and guanosine triphosphate (GTP). These forms play important roles in various biochemical processes such as synthesis of nucleic acids and proteins, photosynthesis, muscle contraction, and intracellular signal transduction (cGMP).
    Guanosine (Standard)
  • HY-N0092R
    Inosine (Standard)

    		Adenosine Receptor Endogenous Metabolite Neurological Disease Inflammation/Immunology
    Inosine (Standard) is the analytical standard of Inosine. This product is intended for research and analytical applications. Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors . In Vitro:Inosine dose-dependently stimulates cAMP production mediated through the A2AR .
    Inosine dose-dependently induces hA2AR-mediated ERK1/2 phosphorylation .
    Inosine (100 μM; 24 hours) reduces oxidative stress in MES 23.5 cells cultured with astrocytes .
    In Vivo:Inosine (10-100 mg/kg; i.p.) exhibits antinociceptive effect in mice .
    Inosine (Standard)

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