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Perfluoroalkyl substances

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W792491
    Perfluoropropanesulfonic acid

    		Others Others
    Perfluoropropanesulfonic acid (PFPrS) is a chemical compound that belongs to the group of perfluoroalkyl substances (PFAS) .
    Perfluoropropanesulfonic acid
  • HY-21195
    Perfluorohexylsulfonyl fluoride

    Perfluorohexanesulphonyl fluoride

    		 Biochemical Assay Reagents Others
    Perfluorohexylsulfonyl fluoride (Perfluorohexanesulphonyl fluoride) is a perfluoroalkyl and polyfluoroalkyl substances, that is defined as persistant organic pollutant by 2022 Stockholm Convention. Perfluorohexylsulfonyl fluoride can be used for drug modification .
    Perfluorohexylsulfonyl fluoride
  • HY-W002199
    6:2 Fluorotelomer alcohol

    6:2 FTOH; 1H,1H,2H,2H-Perfluoro-1-octanol; 2-(Perfluorohexyl)ethanol

    		 Bacterial Infection
    6:2 Fluorotelomer alcohol (6:2 FTOH) is a short-chain perfluoroalkyl substance (PFAS) in polymer PFAS that can be degraded by microbial action, significantly affecting the structure of bacterial communities in sediments and causing changes in the richness and diversity of the bacterial communities .
    6:2 Fluorotelomer alcohol
  • HY-W269593
    Perfluorodecanoic acid

    PFDA

    		 Caspase Interleukin Related Metabolic Disease
    Perfluorodecanoic acid (PFDA) is a perfluoroalkyl substance (PFAS). Perfluorodecanoic acid induces weight loss and increases liver weight and lipid content in mice. Perfluorodecanoic acid also reduces mRNA expression of the genes encoding IL-1β, IL-18, and cellular inhibitor of apoptosis 2 (cIAP2), as well as caspase-1, -3, and -7 in mouse liver .
    Perfluorodecanoic acid
  • HY-21197
    Perfluoroenanthic acid

    Perfluoroheptanoic acid; Tridecafluoroheptanoic acid; PFHpA

    		 iGluR Neurological Disease
    Perfluoroenanthic acid (Perfluoroheptanoic acid) is a type of perfluoroalkyl substance (PFAS) that can negatively impact the development of seminiferous tubules and m6A RNA methylation in the testes of offspring mice when exposed during pregnancy, consequently disrupting spermatogenesis and leading to reproductive toxicity. Perfluoroenanthic acid alters the morphology of dendritic spines and synaptic formation in primary cortical neuron cultures, enhancing neuronal activity and synaptic transmission, and increasing the expression of excitatory synapse-related proteins Synaptophysin and PSD95 .
    Perfluoroenanthic acid
  • HY-W275295
    Perfluorododecanoic acid

    PFDoA

    		 Reactive Oxygen Species (ROS) Metabolic Disease
    Perfluorododecanoic acid (PFDoA) is a perfluoroalkyl substance (PFAS) found in lake trout. Perfluorododecanoic acid decreases the viability of PC12 cells. Perfluorododecanoic acid also increases reactive oxygen species (ROS), malondialdehyde (MDA) levels and reduces the mitochondrial membrane potential in PC12 cells .
    Perfluorododecanoic acid
  • HY-21200
    Perfluoroheptanesulfonic acid

    1-Perfluoroheptanesulfonic acid; Perfluoroheptanesulphonic acid; PFHpS

    		 iGluR Infection
    Perfluoroheptanesulfonic acid (1-Perfluoroheptanesulfonic acid; Perfluoroheptanesulphonic acid) is a perfluoroalkyl substance (PFAS). PFHpS can induce malformations in zebrafish larvae (EC50=168.1 μM). It has also been found in landfill leachate, and fetal exposure to PFHpS can lead to reduced birth weight.
    Perfluoroheptanesulfonic acid
  • HY-W679754
    Pentacosafluorotridecanoic Acid

    PFTrDA

    		 TSH Receptor Infection
    Perfluorotridecanoic acid (PFTrDA) is a perfluoroalkyl substance (PFAS). Embryo larval exposure of PFTrDA induces yolk sac edema and increases mRNA expression of thyroid hormone synthesis genes, including tshβ, in zebrafish when used at concentrations of 0.1 and 0.3 mg/L, respectively. PFTrDA (10 mg/kg) decreases serum testosterone and luteinizing hormone levels, testis palmitic acid, linoleic acid, and oleic acid levels, and the number of Leydig cells in rats in late puberty. Maternal plasma levels of PFTrDA during gestation are positively associated with the development of eczema in female, but not male, infants, and liver levels of PFTrDA are higher in cancerous human livers compared with non-cancerous human livers. It has been found in marine mammals.
    Pentacosafluorotridecanoic Acid
  • HY-W679754R
    Pentacosafluorotridecanoic Acid (Standard)

    PFTrDA (Standard)

    		 TSH Receptor Reference Standards Infection
    Pentacosafluorotridecanoic Acid (Standard) is the analytical standard of Pentacosafluorotridecanoic Acid. This product is intended for research and analytical applications. Perfluorotridecanoic acid (PFTrDA) is a perfluoroalkyl substance (PFAS). Embryo larval exposure of PFTrDA induces yolk sac edema and increases mRNA expression of thyroid hormone synthesis genes, including tshβ, in zebrafish when used at concentrations of 0.1 and 0.3 mg/L, respectively. PFTrDA (10 mg/kg) decreases serum testosterone and luteinizing hormone levels, testis palmitic acid, linoleic acid, and oleic acid levels, and the number of Leydig cells in rats in late puberty. Maternal plasma levels of PFTrDA during gestation are positively associated with the development of eczema in female, but not male, infants, and liver levels of PFTrDA are higher in cancerous human livers compared with non-cancerous human livers. It has been found in marine mammals.
    Pentacosafluorotridecanoic Acid (Standard)

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