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Peptide P-60

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

4

Peptides

1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P1684
    Peptide P60

    FOXP3 inhibitor P60

    		 NF-κB Nuclear Factor of activated T Cells (NFAT) Infection Inflammation/Immunology Cancer
    Peptide P60 is a FOXP3 inhibitor. Peptide P60 can enter cells, inhibit the nuclear translocation of FOXP3, and diminish its ability to suppress the transcription factors NF-κB and NFAT. Peptide P60 can inhibit the immunosuppressive activity of regulatory T cells (Treg) derived from mice and humans, and enhance the stimulation of effector T cells in vitro. Peptide P60 can induce a lymphoproliferative autoimmune syndrome with pathological manifestations resembling those reported in scurfy mice lacking functional Foxp3. Peptide P60 can enhance the immunogenicity of cancer and viral vaccines.
    Peptide P60
  • HY-162946
    Alkyne-P60

    		Ligands for Target Protein for PROTAC Cancer
    Alkyne-P60 is a potent 15-mer peptide inhibitor of Foxp3. Alkyne-P60 can bind with Foxp3, hinder its nuclear translocation, and diminish Foxp3-mediated inhibition of NFKB and NFAT functions. Alkyne-P60 is a ligand for target protein for PROTAC (HY-162943).
    Alkyne-P60
  • HY-P2372
    P60v-src(137-157)

    		Src Others
    P60v-src(137-157) is a synthetic peptide that inhibits the tyrosine kinase activity of p60 v-src (IC50: 7.5 μM) .
    P60v-src(137-157)
  • HY-P3743
    p60c-src Substrate

    		Src Others Others
    p60c-src Substrate is an efficient and specific substrate for p60c-src protein tyrosine kinase (PTK). p60c-src Substrate can be used to synthesize chimeric branched peptides .
    p60c-src Substrate

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