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Results for "

Penicillium

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (17) Apoptosis (8) Autophagy (3) Bacterial (21) Bcl-2 Family (2) Biochemical Assay Reagents (8) c-Met/HGFR (2) Calcium Channel (1) Caspase (1) Cholinesterase (ChE) (2) Cytochrome P450 (2) DNA/RNA Synthesis (1) Drug Derivative (1) Drug Intermediate (5) Drug Isomer (1) Endogenous Metabolite (25) Epigenetic Reader Domain (1) ERK (1) Farnesyl Transferase (1) Fungal (33) Glutathione S-transferase (1) Glycosidase (1) HMG-CoA Reductase (HMGCR) (2) HSV (1) Influenza Virus (3) Insecticide (2) Interleukin Related (2) Isotope-Labeled Compounds (2) Lipoxygenase (1) MEK (1) Microtubule/Tubulin (1) Mitochondrial Metabolism (1) MMP (1) Na+/K+ ATPase (1) Neurokinin Receptor (2) NF-κB (1) Opioid Receptor (3) P-glycoprotein (1) p38 MAPK (1) Parasite (4) PDI (3) Phosphatase (1) Potassium Channel (3) Reactive Oxygen Species (ROS) (4) Reference Standards (8) SOD (2) Trk Receptor (1) Tyrosinase (2)
By Research Areas:	Cancer (24) Cardiovascular Disease (1) Endocrinology (2) Infection (70) Inflammation/Immunology (10) Metabolic Disease (8) Neurological Disease (10)

By Targets:

Antibiotic (17)

Apoptosis (8)

Autophagy (3)

Bacterial (21)

Bcl-2 Family (2)

Biochemical Assay Reagents (8)

c-Met/HGFR (2)

Calcium Channel (1)

Caspase (1)

Cholinesterase (ChE) (2)

Cytochrome P450 (2)

DNA/RNA Synthesis (1)

Drug Derivative (1)

Drug Intermediate (5)

Drug Isomer (1)

Endogenous Metabolite (25)

Epigenetic Reader Domain (1)

ERK (1)

Farnesyl Transferase (1)

Fungal (33)

Glutathione S-transferase (1)

Glycosidase (1)

HMG-CoA Reductase (HMGCR) (2)

HSV (1)

Influenza Virus (3)

Insecticide (2)

Interleukin Related (2)

Isotope-Labeled Compounds (2)

Lipoxygenase (1)

MEK (1)

Microtubule/Tubulin (1)

Mitochondrial Metabolism (1)

MMP (1)

Na+/K+ ATPase (1)

Neurokinin Receptor (2)

NF-κB (1)

Opioid Receptor (3)

P-glycoprotein (1)

p38 MAPK (1)

Parasite (4)

PDI (3)

Phosphatase (1)

Potassium Channel (3)

Reactive Oxygen Species (ROS) (4)

Reference Standards (8)

SOD (2)

Trk Receptor (1)

Tyrosinase (2)

By Research Areas:

Cancer (24)

Cardiovascular Disease (1)

Endocrinology (2)

Infection (70)

Inflammation/Immunology (10)

Metabolic Disease (8)

Neurological Disease (10)

129

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-129591

Paraherquamide A PNU-97333	Others	Others
Paraherquamide A (PNU-97333) is a toxic metabolite that can be isolated from Penicillium paraherquei .

HY-E70103A

*exo-α-Arabinofuranosidase, Penicillium* chrysogenum**	Biochemical Assay Reagents	Others
exo-α-Arabinofuranosidase, Penicillium chrysogenum (EC.3.2.1.55) is a glycoside hydrolase .

HY-E70103K

*exo-α-1,2/3-Arabinofuranosidase, Penicillium* oxalicum**	Biochemical Assay Reagents	Others
exo-α-1,2/3-Arabinofuranosidase,Penicillium oxalicum (EC.3.2.1.55) is a glycoside hydrolase .

HY-E70593

*exo-α-1,5-Arabinanase, Penicillium* chrysogenum**	Biochemical Assay Reagents	Others
exo-α-1,5-Arabinanase, Penicillium chrysogenum is a glycoside hydrolase involved in arabinan decomposition. exo-α-1,5-Arabinanase is capable of cleaving arabinan main chains .

HY-E70103I

*exo-α-1,3-Arabinofuranosidase, Penicillium* chrysogenum**	Biochemical Assay Reagents	Others
exo-α-1,3-Arabinofuranosidase, Penicillium chrysogenum (EC.3.2.1.55) is a glycoside hydrolase that cleaves terminal 1,3-linked-l-Araf residues present at the ends of branched arabinans and arabinogalactans .

HY-120551

Fructigenine A	Others	Others
Fructigenine A (compound 4) is a active product that can be isolated from marine-derived Penicillium sp. .

HY-N12184

Peniciside	Others	Others
Peniciside is a triterpenoid glycoside derived from the fungus Penicillium sp.169 .

HY-N12904

Communesin B (+)-Communesin B; Nomofungin	Others	Cancer
Communesin B ((+)-Communesin B; Nomofungin) has cytotoxicity and can be isolated from Penicillium .

HY-126697

Eremofortin A	Endogenous Metabolite	Others
Eremofortin A is a metabolism that can be isolated from a culture of Penicillium roqueforti .

HY-N12911

Tanzawaic acid E	Others	Others
Tanzawaic acid E is a carboxylic acid and can be isolated from Penicillium steckii .

HY-126484

Eremofortin B	Fungal	Others
Eremofortin B is a sesquiterpenoid compound synthesized by penicillium roqueforti PR Toxin (PRT) .

HY-116479

Citromycetin	Bacterial	Others
Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp .

HY-W741556

Dehydrogriseofulvin	Antibiotic Fungal	Infection
Dehydrogriseofulvin can be isolated from Penicillium sp. Dehydrogriseofulvin inhibits Colletotrichum musae with MIC > 1 µg/scrip.

HY-N12266

12-Hydroxyalbrassitriol	Others	Others
12-Hydroxyalbrassitriol is a drimane sesquiterpenoid that can be isolated from Penicillium sp .

HY-N16447

Territrem C	Cholinesterase (ChE)	Others
Territrem C is an acetylcholinesterase (AchE) inhibitor with an IC₅₀ value of 0.23 μM. Territrem C, which belongs to α-pyrone meroterpenoids, can be isolated and produced from the fungus Penicillium sp. SK5GW1L .

HY-129279

Andrastin A	Farnesyl Transferase	Cancer
Andrastin A meroterpenoid compound, is a farnesyltransferase inhibitor. Andrastin A inhibits the efflux of anticancer compounds from multidrug-resistant cancer cells. Andrastin A can be isolated from Penicillium species .

HY-N7480A

Quinolactacin A1	Cholinesterase (ChE)	Neurological Disease
Quinolactacin A1 is a potent acetylcholinesterase (AChE) inhibitor from solid state fermentation of Penicillium citrinum 90648. Quinolactacin A1 can be used for the research of Alzheimer disease .

HY-P3043

Bilaid A	Opioid Receptor	Neurological Disease
Bilaid A is a μ-opioid receptor agonist that can be extracted from Penicillium. The K_i value is 3.1 μM. Bilaid A can be used in pain research .

HY-N12914

Tanzawaic acid B (+)-Tanzawaic acid B; GS-1302-1; 10-Deoxytanzawaic acid E	Reactive Oxygen Species (ROS)	Others
Tanzawaic acid B ((+)-Tanzawaic acid B; GS-1302-1; 10-Deoxytanzawaic acid E) is a superoxide anion production inhibitor and can be isolated from Penicillium citrinum .

HY-126604

Pyranonigrin A	Others	Infection
Pyranonigrin A is isolated and identified from Penicillium brocae MA-231. Pyranonigrin A shows potent activity against a broad spectrum of human-, aqua-, and plant-pathogens .

HY-N16425

Mitorubrin (-)-Mitorubrin	Influenza Virus	Infection
Mitorubrin ((-)-Mitorubrin) is a compound that can be isolated from Penicillium purpurogenum JS03-21. Mitorubrin shows no significant inhibitory activity against the H1N1 influenza virus (IC₅₀ > 200 μM) .

HY-129806

Rugulosin (+)-Rugulosin	Bacterial Fungal	Infection
Rugulosin is a crystalline colouring matter of Penicillium rugulosum Thom. Rugulosin shows markedly specific antibacterial activity and moderately antifungal activity .

HY-N8287

Oxaline	Microtubule/Tubulin	Cancer
Oxaline is a fungal alkaloid that can be isolated from Penicillium oxalicum. Oxaline inhibits tubulin polymerization, resulting in cell cycle arrest at the M phase .

HY-130757

Remisporine B	Endogenous Metabolite	Inflammation/Immunology
Remisporine B is a polyketide, that can be isolated from Penicillium sp. ZJ-SY2. Remisporine B exhibits immunosuppressive efficacy, that inhibits concanavalin A (HY-P2149)-induced T-cell proliferation and LPS (HY-D1056)- induced B-cell proliferations of mouse splenic lymphocytes with IC₅₀ of 30.1 µg/mL and 32.4 µg/mL .

HY-122076

A-26771B	Antibiotic Bacterial Fungal	Infection
A-26771B is an antibiotic can be obtained from Penicillium turbatum. A-26771B exhibits moderate antimicrobial activity against Gram-positive bacteria, mycoplasma, and fungi. A-26771B also inhibits potassium-dependent ATPase in rat liver mitochondria .

HY-N16393

(-)-Mitorubrinol Mitorubrinol	Others	Cancer
(-)-Mitorubrinol is found in the marine-derived Penicillium purpurogenum G59 strain induced by diethyl sulfate (DES). (-)-Mitorubrinol exhibits inhibitory effects on K562, HL-60, HeLa, and BGC-823 cancer cell lines .

HY-W099579

Kojic acid dipalmitate Kojic dipalmitate	Tyrosinase	Endocrinology
Kojic acid dipalmitate (Kojic dipalmitate) is a derivative of Kojic acid (HY-W050154), a fungal metabolite that can be produced by species of Aspergillus, Acetobacter and Penicillium. Kojic acid dipalmitate is a slow and reversible competitive inhibitor of tyrosinase. Kojic acid dipalmitate can be used for skin‐lightening agent research .

HY-N12761

Penpaxilloids A	Phosphatase Glycosidase	Metabolic Disease Inflammation/Immunology
Penpaxilloids A (Compound 1) is a non-competitive inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC₅₀ value of 8.60 μM. Penpaxilloids A can be isolated from the fungus Penicillium sp. ZYX-Z-143. Penpaxilloids A is also an α-glucosidase (α-glucosidase) inhibitor with anti-inflammatory activity .

HY-N12165

1,3,5,6-Tetrahydroxy-8-methylxanthone	Others	Others
1,3,5,6-Tetrahydroxy-8-methylxanthone (compound 8) is a dimeric 1,4-benzoquinone derivative isolated from the marine-derived fungus Penicillium genus .

HY-118463

Benzomalvin A (-)-Benzomalvin A	Neurokinin Receptor	Neurological Disease
Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with K_i values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively .

HY-W099579R

Kojic acid dipalmitate (Standard) Kojic dipalmitate (Standard)	Reference Standards Tyrosinase	Endocrinology
Kojic acid dipalmitate (Standard) is the analytical standard of Kojic acid dipalmitate. This product is intended for research and analytical applications. Kojic acid dipalmitate (Kojic dipalmitate) is a derivative of Kojic acid (HY-W050154), a fungal metabolite that can be produced by species of Aspergillus, Acetobacter and Penicillium. Kojic acid dipalmitate is a slow and reversible competitive inhibitor of tyrosinase. Kojic acid dipalmitate can be used for skin‐lightening agent research .

HY-N10177

Peniterphenyl A	HSV	Infection
Peniterphenyl A is a natural product obtained from a deep-sea-derived Penicillium sp. Peniterphenyl A inhibits HSV-1/2 virus entry into cells and may block HSV-1/2 infection through direct interaction with virus envelope glycoprotein D to interfere with virus adsorption and membrane fusion. Peniterphenyl A is a promising lead compound against HSV-1/2 .

HY-P10329

KK14(R)	Fungal	Infection
KK14(R) is an analog of the de novo synthetic peptide KK14, which exhibits antifungal activity against Fusarium culmorum, Penicillium expansum and Aspergillus niger , with MICs of 6.25, 12.5 and 12.5 μg/mL, respecitvely. KK14(R) exhibits good heat- and pH-stability. KK14(R) exhibits cytotoxicity against cells Caco-2 and RAW264.7 .

HY-N6748

Roquefortine C 1 Publications Verification	P-glycoprotein Cytochrome P450 Bacterial c-Met/HGFR	Infection Neurological Disease Cancer
Roquefortine C is a mycotoxin that can be isolated from Penicillium species. Roquefortine C is an agonist of P-gp and an inhibitor of P450 3A and P450 1A. Roquefortine C can inhibit Gram-positive bacteria and also has certain neurotoxicity. Additionally, Roquefortine C can exert antitumor activity .

HY-P5591

PAF26	Fungal	Infection
PAF26 is an antimicrobial peptide against phytopathogenic fungi Penicillium digitatum, Penicillium italicum and Botrytis cinerea .

HY-N14509

Queenslandon	Fungal	Infection
Queenslandon has moderate anti-streptomyces, penicillium, Penicillium, Aspergillus fumigatus, aspergillus flavus and other fungal activities. And it has no effect on bacteria .

HY-N10215

Canadensolide	Fungal Endogenous Metabolite	Infection
Canadensolide is an antifungal metabolite of Penicillium canadense.

HY-121332

Cyclopeptine	Drug Intermediate	Infection
Cyclopeptine is an intermediate in the synthesis of benzodiazepine alkaloids in Penicillium.

HY-133001

Dehydrocyclopeptine	Drug Intermediate	Infection
Dehydrocyclopeptine is an intermediate in the synthesis of benzodiazepine alkaloids in Penicillium.

HY-136871

Decarestrictin A1	Endogenous Metabolite	Infection
Decarestrictine A1 is a fungal metabolite that has been found in Penicillium.

HY-N16439

Phenicin Phoenicine	HMG-CoA Reductase (HMGCR)	Others
Phenicin (Phoenicine), a microbial metabolite, is an irreversible HMG-CoA reductase (HMGCR) inhibitor. Phenicin can be isolated from cultures of Penicillium phoeniceum and Penicillium rubrum. Phenicin specifically inhibits the conversion of HMG-CoA to mevalonate catalyzed by HMGCR, effectively inhibiting cholesterol synthesis .

HY-N7221

Janthitrem G	Fungal	Infection
Janthitrem G is a microbial metabolite that can be isolated from cultures of Penicillium .

HY-N8548

Fellutanine A	Endogenous Metabolite	Infection
Fellutanine A, a diketopiperazine alkaloid, is a fungal metabolite from cultures of Penicillium fellutanum .

HY-125298

Cycloaspeptide A	Parasite	Infection
Cycloaspeptide A, isolated from the endophytic fungus Penicillium janczewskii, has antiparasitic activity .

HY-172191

Czapek dox agar	Biochemical Assay Reagents	Others
Czapek dox agar can be used to identify and preserve strains of Penicillium and Aspergillus .

HY-N14486

Neihumicin	Fungal	Infection
Neihumicin is resistant to beer Saccharomyces yeast ATCC 9763 and Penicillium italium Wehmer, but not to bacteria .

HY-123474

PF-1163B	Fungal Antibiotic	Infection
PF-1163B is an antifungal antibiotic .

HY-129208

Viridicatumtoxin	Antibiotic Fungal	Infection
Viridicatumtoxin is a new mycotoxin extracted from Penicillium viridicatum with a LD₅₀ of 122.4 mg/kg in rats.

HY-120154

Palitantin (±)-Palitantin	Parasite Endogenous Metabolite	Infection
Palitantin ((±)-Palitantin), a metabolite of Penicillium frequentans on Leishmania brasiliensis, has antiprotozoal effect against Leishmania brasiliensis .

HY-W988083

Decarestrictin B	Endogenous Metabolite	Metabolic Disease
Decarestrictin B is a decanolactone that can be isolated from penicillium strains. Decarestrictin B is an inhibitor of cholesterol biosynthesis .

Cat. No.	Product Name	Type

HY-W093399

Ammonium bicarbonate,AR,99% 2 Publications Verification	Biochemical Assay Reagents
Ammonium bicarbonate,AR,99% is an analytical reagent-grade ammonium bicarbonate. Ammonium bicarbonate has antifungal activity. Ammonium bicarbonate is widely used in laboratory analysis, food processing, agricultural fertilization and other fields .

HY-172191

Czapek dox agar	Microbial Culture
Czapek dox agar can be used to identify and preserve strains of Penicillium and Aspergillus .

Cat. No.	Product Name	Target	Research Area

HY-N6748

Roquefortine C 1 Publications Verification	P-glycoprotein Cytochrome P450 Bacterial c-Met/HGFR	Infection Neurological Disease Cancer
Roquefortine C is a mycotoxin that can be isolated from Penicillium species. Roquefortine C is an agonist of P-gp and an inhibitor of P450 3A and P450 1A. Roquefortine C can inhibit Gram-positive bacteria and also has certain neurotoxicity. Additionally, Roquefortine C can exert antitumor activity .

HY-P5591

PAF26	Fungal	Infection
PAF26 is an antimicrobial peptide against phytopathogenic fungi Penicillium digitatum, Penicillium italicum and Botrytis cinerea .

HY-N11955

Cyclo(Ile-Leu)	Peptides	Others
Cyclo(Ile-Leu) is a Alkaloids product that can be isolated from From Penicillium oxalicum .

HY-75564

Cyclo(Ala-Gly)	Endogenous Metabolite	Cancer
Cyclo(Ala-Gly), a metabolite of a mangrove endophytic fungus, Penicillium thomi, exhibits cytotoxicity against A549, HepG2 and HT29 cells. The IC₅₀ values range from 9.5 to 18.1 μM .

HY-P3519

ACV Tripeptide	Drug Intermediate	Others
ACV Tripeptide is a key biosynthetic precursor of penicillin and cephalosporins and is found in Penicillium chrysogenum and Acremonium chrysogenum. ACV Tripeptide is synthesized by a large non-ribosomal peptide synthase called ACV synthase, which is encoded by the 11 kb The pchAB gene encodes this enzyme .

HY-P5941

Bilaid C1	Peptides	Others
Bilaid C1 is a tetrapeptide isolated from Penicillium sp .

HY-P3043

Bilaid A	Opioid Receptor	Neurological Disease
Bilaid A is a μ-opioid receptor agonist that can be extracted from Penicillium. The K_i value is 3.1 μM. Bilaid A can be used in pain research .

HY-P10329

KK14(R)	Fungal	Infection
KK14(R) is an analog of the de novo synthetic peptide KK14, which exhibits antifungal activity against Fusarium culmorum, Penicillium expansum and Aspergillus niger , with MICs of 6.25, 12.5 and 12.5 μg/mL, respecitvely. KK14(R) exhibits good heat- and pH-stability. KK14(R) exhibits cytotoxicity against cells Caco-2 and RAW264.7 .

HY-P4107

Bilaid C	Opioid Receptor	Neurological Disease
Bilaid C, a tetrapeptide, can be isolated from the Australian estuarine isolate of Penicillium sp. MST-MF667. Bilaid C is also a potent and selective μ-Opioid Receptor (MOPr) agonist (K_i=210 nM, hMOPr) .

HY-P3044

Bilaid A1e	Opioid Receptor	Neurological Disease
Bilaid A1e (Compound 1e) is a tetrapeptide agonist of the µ-opioid receptor (K_i = 750 nM). Bilaid A1e can be isolated from an Australian estuarine isolate of Penicillium sp. Bilaid A1e can be used for pain research .

HY-P3519A

ACV Tripeptide TFA	Drug Intermediate	Others
ACV Tripeptide TFA is the TFA form of ACV Tripeptide (HY-P3519). ACV Tripeptide TFA is a key biosynthetic precursor of penicillin and cephalosporins and is found in Penicillium chrysogenum and Acremonium chrysogenum. ACV Tripeptide TFA is synthesized by a large non-ribosomal peptide synthase called ACV synthase .

HY-P2032

Cyclochlorotine	Endogenous Metabolite	Infection Cancer
Cyclochlorotine is a mycotoxin that can be extracted from the yellow rice infectant Penicillium islandicum Sopp. Cyclochlorotine promotes glycogenolysis, inhibits glycogen synthesis, affects fat synthesis and protein synthesis in liver cells. Cyclochlorotine exhibits chronic toxicity in liver that induces liver fibrosis and cirrhosis in mouse models. Cyclochlorotine exhibits carcinogenicity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-120551

Fructigenine A	Natural Products Microorganisms Source classification	Others
Fructigenine A (compound 4) is a active product that can be isolated from marine-derived Penicillium sp. .

HY-N12184

Peniciside	Triterpenes Microorganisms Terpenoids Source classification	Others
Peniciside is a triterpenoid glycoside derived from the fungus Penicillium sp.169 .

HY-N12904

Communesin B (+)-Communesin B; Nomofungin	Alkaloids Microorganisms Other Alkaloids Source classification	Others
Communesin B ((+)-Communesin B; Nomofungin) has cytotoxicity and can be isolated from Penicillium .

HY-126697

Eremofortin A	Natural Products Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
Eremofortin A is a metabolism that can be isolated from a culture of Penicillium roqueforti .

HY-N12911

Tanzawaic acid E	Microorganisms Antibiotics Source classification Other Antibiotics	Others
Tanzawaic acid E is a carboxylic acid and can be isolated from Penicillium steckii .

HY-126484

Eremofortin B	Natural Products Microorganisms Source classification	Fungal
Eremofortin B is a sesquiterpenoid compound synthesized by penicillium roqueforti PR Toxin (PRT) .

HY-116479

Citromycetin	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Marine natural products Source classification Other Diseases Phenols Polyphenols Marine microorganism Disease Research Fields	Bacterial
Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp .

HY-N12266

12-Hydroxyalbrassitriol	Microorganisms Terpenoids Sesquiterpenes Source classification	Others
12-Hydroxyalbrassitriol is a drimane sesquiterpenoid that can be isolated from Penicillium sp .

HY-N16447

Territrem C	Monophenols Microorganisms Source classification Phenols	Cholinesterase (ChE)
Territrem C is an acetylcholinesterase (AchE) inhibitor with an IC₅₀ value of 0.23 μM. Territrem C, which belongs to α-pyrone meroterpenoids, can be isolated and produced from the fungus Penicillium sp. SK5GW1L .

HY-129279

Andrastin A	Natural Products Microorganisms Source classification	Farnesyl Transferase
Andrastin A meroterpenoid compound, is a farnesyltransferase inhibitor. Andrastin A inhibits the efflux of anticancer compounds from multidrug-resistant cancer cells. Andrastin A can be isolated from Penicillium species .

HY-N7480A

Quinolactacin A1	Alkaloids Microorganisms Pyrrole Alkaloids Classification of Application Fields Neurological Disease Source classification Quinoline Alkaloids Disease Research Fields	Cholinesterase (ChE)
Quinolactacin A1 is a potent acetylcholinesterase (AChE) inhibitor from solid state fermentation of Penicillium citrinum 90648. Quinolactacin A1 can be used for the research of Alzheimer disease .

HY-N12914

Tanzawaic acid B (+)-Tanzawaic acid B; GS-1302-1; 10-Deoxytanzawaic acid E	Microorganisms Antibiotics Source classification Other Antibiotics	Reactive Oxygen Species (ROS)
Tanzawaic acid B ((+)-Tanzawaic acid B; GS-1302-1; 10-Deoxytanzawaic acid E) is a superoxide anion production inhibitor and can be isolated from Penicillium citrinum .

HY-126604

Pyranonigrin A	Infection Alkaloids Human Gut Microbiota Metabolites Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Others
Pyranonigrin A is isolated and identified from Penicillium brocae MA-231. Pyranonigrin A shows potent activity against a broad spectrum of human-, aqua-, and plant-pathogens .

HY-N16425

Mitorubrin (-)-Mitorubrin	Microorganisms Source classification Phenols Polyphenols	Influenza Virus
Mitorubrin ((-)-Mitorubrin) is a compound that can be isolated from Penicillium purpurogenum JS03-21. Mitorubrin shows no significant inhibitory activity against the H1N1 influenza virus (IC₅₀ > 200 μM) .

HY-N8287

Oxaline	Alkaloids Microorganisms Other Alkaloids Source classification	Microtubule/Tubulin
Oxaline is a fungal alkaloid that can be isolated from Penicillium oxalicum. Oxaline inhibits tubulin polymerization, resulting in cell cycle arrest at the M phase .

HY-130757

Remisporine B	Microorganisms Xanthones Source classification Phenols	Endogenous Metabolite
Remisporine B is a polyketide, that can be isolated from Penicillium sp. ZJ-SY2. Remisporine B exhibits immunosuppressive efficacy, that inhibits concanavalin A (HY-P2149)-induced T-cell proliferation and LPS (HY-D1056)- induced B-cell proliferations of mouse splenic lymphocytes with IC₅₀ of 30.1 µg/mL and 32.4 µg/mL .

HY-N16393

(-)-Mitorubrinol Mitorubrinol	Microorganisms Source classification Phenols Polyphenols	Others
(-)-Mitorubrinol is found in the marine-derived Penicillium purpurogenum G59 strain induced by diethyl sulfate (DES). (-)-Mitorubrinol exhibits inhibitory effects on K562, HL-60, HeLa, and BGC-823 cancer cell lines .

HY-N12761

Penpaxilloids A	Terpenoids Marine natural products Source classification Diterpenoids Marine microorganism	Phosphatase Glycosidase
Penpaxilloids A (Compound 1) is a non-competitive inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC₅₀ value of 8.60 μM. Penpaxilloids A can be isolated from the fungus Penicillium sp. ZYX-Z-143. Penpaxilloids A is also an α-glucosidase (α-glucosidase) inhibitor with anti-inflammatory activity .

HY-N12165

1,3,5,6-Tetrahydroxy-8-methylxanthone	Flavonoids Microorganisms Xanthones Source classification Phenols Other Flavonoids	Others
1,3,5,6-Tetrahydroxy-8-methylxanthone (compound 8) is a dimeric 1,4-benzoquinone derivative isolated from the marine-derived fungus Penicillium genus .

HY-118463

Benzomalvin A (-)-Benzomalvin A	Alkaloids Human Gut Microbiota Metabolites Microorganisms Source classification Quinoline Alkaloids Endogenous metabolite	Neurokinin Receptor
Benzomalvin A is a potent antagonist of neurokinin receptor isolated from Penicillium sp. Benzomalvin A shows inhibitory activity against substance P with K_i values of 12, 42 and 43 μM at the guinea pig, rat and human neurokinin NK1 receptors, respectively .

HY-N10177

Peniterphenyl A	Infection Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Disease Research Fields	HSV
Peniterphenyl A is a natural product obtained from a deep-sea-derived Penicillium sp. Peniterphenyl A inhibits HSV-1/2 virus entry into cells and may block HSV-1/2 infection through direct interaction with virus envelope glycoprotein D to interfere with virus adsorption and membrane fusion. Peniterphenyl A is a promising lead compound against HSV-1/2 .

HY-N6748

Roquefortine C 1 Publications Verification	Infection Microorganisms Classification of Application Fields Cyclopeptides Source classification Disease Research Fields	P-glycoprotein Cytochrome P450 Bacterial c-Met/HGFR
Roquefortine C is a mycotoxin that can be isolated from Penicillium species. Roquefortine C is an agonist of P-gp and an inhibitor of P450 3A and P450 1A. Roquefortine C can inhibit Gram-positive bacteria and also has certain neurotoxicity. Additionally, Roquefortine C can exert antitumor activity .

HY-N14509

Queenslandon	Microorganisms Antibiotics Source classification Other Antibiotics	Fungal
Queenslandon has moderate anti-streptomyces, penicillium, Penicillium, Aspergillus fumigatus, aspergillus flavus and other fungal activities. And it has no effect on bacteria .

HY-N10215

Canadensolide	Infection Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Fungal Endogenous Metabolite
Canadensolide is an antifungal metabolite of Penicillium canadense.

HY-N16439

Phenicin Phoenicine	Natural Products Microorganisms Source classification	HMG-CoA Reductase (HMGCR)
Phenicin (Phoenicine), a microbial metabolite, is an irreversible HMG-CoA reductase (HMGCR) inhibitor. Phenicin can be isolated from cultures of Penicillium phoeniceum and Penicillium rubrum. Phenicin specifically inhibits the conversion of HMG-CoA to mevalonate catalyzed by HMGCR, effectively inhibiting cholesterol synthesis .

HY-N7221

Janthitrem G	Microorganisms Terpenoids Source classification Diterpenoids	Fungal
Janthitrem G is a microbial metabolite that can be isolated from cultures of Penicillium .

HY-N8548

Fellutanine A	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids	Endogenous Metabolite
Fellutanine A, a diketopiperazine alkaloid, is a fungal metabolite from cultures of Penicillium fellutanum .

HY-125298

Cycloaspeptide A	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Cycloaspeptide A, isolated from the endophytic fungus Penicillium janczewskii, has antiparasitic activity .

HY-N14486

Neihumicin	Microorganisms Antibiotics Source classification Other Antibiotics	Fungal
Neihumicin is resistant to beer Saccharomyces yeast ATCC 9763 and Penicillium italium Wehmer, but not to bacteria .

HY-N11955

Cyclo(Ile-Leu)	Alkaloids Microorganisms Other Alkaloids Marine natural products Source classification Endogenous metabolite	Others
Cyclo(Ile-Leu) is a Alkaloids product that can be isolated from From Penicillium oxalicum .

HY-123474

PF-1163B	Microorganisms Ketones, Aldehydes, Acids Source classification	Fungal Antibiotic
PF-1163B is an antifungal antibiotic .

HY-129208

Viridicatumtoxin	Other Terpenoids Infection Microorganisms Classification of Application Fields Terpenoids Source classification Disease Research Fields	Antibiotic Fungal
Viridicatumtoxin is a new mycotoxin extracted from Penicillium viridicatum with a LD₅₀ of 122.4 mg/kg in rats.

HY-120154

Palitantin (±)-Palitantin	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Parasite Endogenous Metabolite
Palitantin ((±)-Palitantin), a metabolite of Penicillium frequentans on Leishmania brasiliensis, has antiprotozoal effect against Leishmania brasiliensis .

HY-N14783

Decarestrictin M	Microorganisms Antibiotics Source classification Other Antibiotics	Endogenous Metabolite
Decarestrictin M is a decanolactone that can be isolated from penicillium strains. Decarestrictin M is an inhibitor of cholesterol biosynthesis .

HY-N15658

Isopatulin	Natural Products Microorganisms Source classification	Biochemical Assay Reagents
Isopatulin can be isolated from the marine isolate of the fungus Penicillium claviforme associated with the seagrass Zostera marina .

HY-125546

Erythromycin C	Natural Products Microorganisms Source classification	Antibiotic
Erythromycin C is an antibiotic. Erythromycin C could be isolated from the fermentation process of the penicillium Streptomyces erythreus .

HY-N10220

Paraherquamide E	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields	Endogenous Metabolite Parasite
Paraherquamide E is a fungal metabolite found in Penicillium charlesii. Paraherquamide E has antinematodal and antiparasitic effects .

HY-N13086

Peniviridiol A	Microorganisms Terpenoids Sesquiterpenes Source classification	Others
Peniviridiol A (compound4) is a viridin derivative that can be isolated from rhizosphere fungus Penicillium sp. SMU0102 .

HY-N7222

Janthitrem F	Microorganisms Terpenoids Source classification Diterpenoids	Fungal
Janthitrem F is a metabolite isolated from tremorigen-producing Penicillium and a potential causative agent of ryegrass spurt disease .

HY-125060

Viridicatin	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Quinoline Alkaloids Disease Research Fields	Antibiotic Endogenous Metabolite
Viridicatin is a fungal metabolite from Penicillium species. Viridicatin shows slight in vitro antibiotic activity against Mycobacterium tuberculosis .

HY-N10442

Herqueilenone A	Quinones Microorganisms Source classification Benzene Quinones	Others
Herqueilenone A is a benzoquinone-chromanon that can be found in the Hawaiian volcanic soil-associated fungal strain Penicillium herquei FT729[1].

HY-N14225

Fumifungin	Microorganisms Antibiotics Source classification Other Antibiotics	Fungal
Fumifungin has the antifungal activities of Cercospora, Cladosporium, Aspergillus niger, Penicillium digitatum, Trichophyton mentagrophytes, Alternaria, Candida albicans and yeast .

HY-124301

Penicolinate A	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Pyridine Alkaloids Disease Research Fields	Bacterial
Penicolinate A is a picolinic acid derivative. Penicolinate A is isolated from endophytic Penicillium sp. BCC16054. Penicolinate A exhibits antimalarial and antitubercular activities .

HY-122404

Xantocillin Xanthocillin X	Microorganisms Classification of Application Fields Source classification Marine natural products Phenols Polyphenols Disease Research Fields Marine microorganism Cancer	MEK ERK Autophagy
Xantocillin (Xanthocillin X) is a marine agent extracted from Penicillium commune, induces autophagy through inhibition of the MEK/ERK pathway .

HY-N14665

Atrovenetin	Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Bacterial
Atrovenetin is an antibiotic found in Penicillium species. Atrovenetin has inhibitory activity against Bacillus subtilis and Staphylococcus aureus. Atrovenetin is also a potent antioxidant.

HY-N15097

Dihydrocompactin	Natural Products Microorganisms Source classification	Antibiotic Fungal HMG-CoA Reductase (HMGCR)
Dihydrocompactin, an antifungal metabolite, is an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme-A reductase (HMG-CoA reductase) from Penicillium citrinum .

HY-W780198

Endophenazine A	Microorganisms Antibiotics Source classification Other Antibiotics	Bacterial Fungal
Endophenazine A has activity against Gram-positive bacteria and filamentous fungi such as mucor and Penicillium. Its weeding ability to Lemna minor is relatively low .

HY-W152146

Methylxanthoxylin	Monophenols Source classification Phenols Myrtaceae Syzygium aromaticum (L.) Merr. & L.M.Perry Plants	Fungal
Methylxanthoxylin is a ketone that can be isolated from the leaves and bark of Acradenia Jianklinii . Methylxanthoxylin exhibited moderate antifungal activity against Candida albicans and Penicillium expansum .

HY-126983

6',7'-Epoxybergamottin Epoxybergamottin	Natural Products Microorganisms Source classification	Cytochrome P450
6',7'-Epoxybergamottin is a metabolism of Penicillium digitatum. 6',7'-Epoxybergamottin can be used in study the cytochrome P450 3A4 inhibitory activity .

HY-116812

Sclerotigenin	Natural Products Microorganisms Source classification	Insecticide
Sclerotigenin is an anti-insect benzodiazepine compound identified in Penicillium sclerotigenum (NRRL 3461). Sclerotigenin exhibits significant anti-insect activity against crop pest Helicoverpa zea .

Cat. No.	Product Name	Chemical Structure

HY-N6779S

Patulin-13C7
Patulin- ¹³C₇ (Terinin- ¹³C₇) is the ¹³C labeled Patulin (HY-N6779) . Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, is suspected to be clastogenic, mutagenic, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage .

HY-W015912S

2-Acetylfuran-d3

2-Acetylfuran-d₃ is deuterated labeled Citreoviridin (HY-N6745). Citreoviridin, a toxin from Penicillium citreoviride NRRL 2579, inhibits brain synaptosomal Na ⁺/K ⁺-ATPase whereas in microsomes, both Na ⁺/K ⁺-ATPase and Mg ²⁺-ATPase activities are significantly stimulated in a dose-dependent manner . Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells .

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