PBR

By Targets:	ADC Payload (3) DNA Alkylator/Crosslinker (1) DNA/RNA Synthesis (1) GABA Receptor (4) iGluR (4) Platelet-activating Factor Receptor (PAFR) (1) Reactive Oxygen Species (ROS) (1) Reference Standards (3) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (4) Cardiovascular Disease (1) Inflammation/Immunology (1) Neurological Disease (8)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-153248

PBR28	Others	Others
PBR28 is an TSPO modulator, which can be used for prevention research of Pulmonary Arterial Hypertension (PAH). PBR28 can be used to trace 18 KDa transporter (TSPO) by adding radioactive labeling, which plays an important role in brain positron emission tomography (PET) imaging studies .

HY-101059

FGIN 1-27	GABA Receptor	Neurological Disease
FGIN 1-27, an indoleacetamide, is a specific peripheral benzodiazepine receptor (PBR) ligand with a K_i of 5.0 nM. FGIN 1-27 can penetrate the blood brain barrier (BBB). FGIN 1-27 inhibits the onset of Isoniazid-induced convulsions .

HY-19945

DAA-1106 1 Publications Verification	GABA Receptor	Neurological Disease
DAA1106 is a potent and selective ligand for peripheral benzodiazepine receptor (PBR), as a potent and selective agonist at the peripheral benzodiazepine receptor.

HY-14573

SJG-136 3 Publications Verification NSC-694501	DNA Alkylator/Crosslinker ADC Payload	Cancer
SJG-136 is a DNA cross-linking agent, with an XL₅₀ of 45 nM for pBR322 DNA. SJG-136 has potent antitumor activity.

HY-402091

SJG-136 intermediate-1	ADC Payload	Others
SJG-136 intermediate-1 (compound 19) is an intermediate for synthesizing SJG-136. SJG-136 is a DNA cross-linking agent, with an XL₅₀ of 45 nM for pBR322 DNA .

HY-119605

DAA-1097	GABA Receptor	Neurological Disease
DAA-1097 is an orally active and selective agonist for the peripheral benzodiazepine receptor (PBR). DAA-1097 has anxiolytic effects .

HY-101059R

FGIN 1-27 (Standard)	GABA Receptor Reference Standards	Neurological Disease
FGIN 1-27 (Standard) is the analytical standard of FGIN 1-27. This product is intended for research and analytical applications. FGIN 1-27, an indoleacetamide, is a specific peripheral benzodiazepine receptor (PBR) ligand with a Ki of 5.0 nM. FGIN 1-27 can penetrate the blood brain barrier (BBB). FGIN 1-27 inhibits the onset of Isoniazid-induced convulsions .

HY-402090

SJG-136 intermediate-2	ADC Payload	Others
SJG-136 intermediate-2 (compound 141) is an intermediate for synthesizing SJG-136. SJG-136 is a DNA cross-linking agent, with an XL₅₀ of 45 nM for pBR322 DNA .

HY-N1994

Swertianine	Reactive Oxygen Species (ROS)	Inflammation/Immunology
Swertianine is a hydroxyexanthone that can be isolated from Swertia decussata. Swertianine has antioxidant activity by inhibiting lipid peroxidation, scavenging DPPH and superoxide free radicals. Swertianine also inhibits γ-ray induced DNA damage of pBR322 with protective effect .

HY-N1620

1-Cinnamoylpyrrolidine	DNA/RNA Synthesis Platelet-activating Factor Receptor (PAFR)	Cardiovascular Disease
1-Cinnamoylpyrrolidine (Compound 3), a crude extract prepared from Piper caninum, is a DNA strand scission agent, induces the relaxation of supercoiled pBR322 plasmid DNA . 1-Cinnamoylpyrrolidine (Compound 4) inhibits platelet aggregation induced by PAF with an IC₅₀ of 37.3 μM .

HY-RS16721

Tspo Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Tspo Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tspo gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Tspo Mouse Pre-designed siRNA Set A Tspo Mouse Pre-designed siRNA Set A

HY-B1126R

Orphenadrine hydrochloride (Standard)	Reference Standards iGluR	Neurological Disease Cancer
Orphenadrine (hydrochloride) (Standard) is the analytical standard of Orphenadrine (hydrochloride). This product is intended for research and analytical applications. Orphenadrine hydrochloride is an orally active and non-competitive NMDA receptor antagonist (crosses the blood-brain barrier) with a Ki of 6.0 μM. Orphenadrine hydrochloride relieves stiffness, pain and discomfort due to muscle strains, sprains or other injuries. Orphenadrine hydrochloride is also used to relieve tremors associated with parkinson's disease. Orphenadrine citrate has good neuroprotective properties, can be used in studies of neurodegenerative diseases .

HY-B1126

Orphenadrine hydrochloride	iGluR	Neurological Disease Cancer
Orphenadrine hydrochloride is an orally active and non-competitive NMDA receptor antagonist (crosses the blood-brain barrier) with a K_i of 6.0 μM. Orphenadrine hydrochloride relieves stiffness, pain and discomfort due to muscle strains, sprains or other injuries. Orphenadrine hydrochloride is also used to relieve tremors associated with parkinson's disease. Orphenadrine citrate has good neuroprotective properties, can be used in studies of neurodegenerative diseases .

HY-B0369A

Orphenadrine citrate	iGluR	Neurological Disease Cancer
Orphenadrine citrate is an orally active and non-competitive NMDA receptor antagonist (crosses the blood-brain barrier) with a K_i of 6.0 μM. Orphenadrine citrate relieves stiffness, pain and discomfort due to muscle strains, sprains or other injuries. Orphenadrine citrate is also used to relieve tremors associated with parkinson's disease. Orphenadrine citrate has good neuroprotective properties, can be used in studies of neurodegenerative diseases .

HY-B0369AR

Orphenadrine citrate (Standard)	Reference Standards iGluR	Neurological Disease
Orphenadrine (citrate) (Standard) is the analytical standard of Orphenadrine (citrate). This product is intended for research and analytical applications. Orphenadrine citrate is an orally active and non-competitive NMDA receptor antagonist (crosses the blood-brain barrier) with a Ki of 6.0 μM. Orphenadrine citrate relieves stiffness, pain and discomfort due to muscle strains, sprains or other injuries. Orphenadrine citrate is also used to relieve tremors associated with parkinson's disease. Orphenadrine citrate has good neuroprotective properties, can be used in studies of neurodegenerative diseases .

HY-RS15177

TSPO Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TSPO Human Pre-designed siRNA Set A contains three designed siRNAs for TSPO gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TSPO Human Pre-designed siRNA Set A TSPO Human Pre-designed siRNA Set A

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1994

Swertianine	Structural Classification Flavonoids Xanthones Flavones Source classification Swertia bimaculata (Sieb. et Zucc.) Hook. f. et Thoms. ex C. B. Clark Gentianaceae Phenols Plants	Reactive Oxygen Species (ROS)
Swertianine is a hydroxyexanthone that can be isolated from Swertia decussata. Swertianine has antioxidant activity by inhibiting lipid peroxidation, scavenging DPPH and superoxide free radicals. Swertianine also inhibits γ-ray induced DNA damage of pBR322 with protective effect .

HY-N1620

1-Cinnamoylpyrrolidine	Cardiovascular Disease Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Disease Research Fields	DNA/RNA Synthesis Platelet-activating Factor Receptor (PAFR)
1-Cinnamoylpyrrolidine (Compound 3), a crude extract prepared from Piper caninum, is a DNA strand scission agent, induces the relaxation of supercoiled pBR322 plasmid DNA . 1-Cinnamoylpyrrolidine (Compound 4) inhibits platelet aggregation induced by PAF with an IC₅₀ of 37.3 μM .

Cat. No.	Compare	Product Name	Species	Source

HY-P702478

	TSPO Protein, Mouse (Cell-Free, His) Translocator protein; Mitochondrial benzodiazepine receptor; PKBS; Peripheral-type benzodiazepine receptor; PBR	Mouse	E. coli Cell-free
	The TSPO protein was originally thought to be a peripheral benzodiazepine receptor that binds protoporphyrin IX and isoquinoline carboxamide. TSPO Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived TSPO protein, expressed by E. coli Cell-free , with N-10*His labeled tag.

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Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P82040

	PBR Antibody (YA1785) TSPO; BZRP; MBR; Translocator protein; Mitochondrial benzodiazepine receptor; PKBS; Peripheral-type benzodiazepine receptor; PBR	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse
	PBR Antibody (YA1785) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1785), targeting PBR, with a predicted molecular weight of 11 kDa (observed band size: 19 kDa). PBR Antibody (YA1785) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse background.

HY-P87004

	PBR Antibody (YA6697) Benzodiazapine receptor (peripheral) antibody; Benzodiazepine peripheral binding site antibody; BPBS antibody; BZRP antibody; DBI antibody; IBP antibody; Isoquinoline carboxamide-binding protein antibody; MBR antibody; mDRC antibody; Mitochondrial benzodiazepine receptor antibody; Benzodiazapine receptor (peripheral) antibody; Benzodiazepine peripheral binding site antibody; BPBS antibody; BZRP antibody; DBI antibody; IBP antibody; Isoquinoline carboxamide-binding protein antibody; MBR antibody; mDRC antibody; Mitochondrial benzodiazepine receptor antibody; PBR antibody; PBS antibody; Peripheral benzodiazepine receptor antibody; Peripheral benzodiazepine receptor-related protein antibody; Peripheral type benzodiazepine receptor antibody; Peripheral-type benzodiazepine receptor antibody; pk18 antibody; PKBS antibody; PTBR antibody; Ptbzr antibody; PTBZR02 antibody; RATPTBZR02 antibody; translocator protein (18kDa) antibody; Translocator protein antibody; Tspo antibody; Tspo1 antibody; TSPOA_HUMAN antibody	WB, ICC/IF, IF-Tissue, IHC-P, IP, FC	Human, Mouse, Rat

HY-P86428

	E2F-1 Antibody (YA6120) E2F1; RBBP3; Transcription factor E2F1; E2F-1; PBR3; Retinoblastoma-associated protein 1; RBAP-1; Retinoblastoma-binding protein 3; RBBP-3; pRB-binding protein E2F-1	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	E2F-1 Antibody (YA6120) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to E2F-1. It can be applicated for WB, IHC-P, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

HY-P85613

	E2F-1 Antibody (YA5305) Dmel\CG6376; Dmel_CG6376; drosE2F1; E; Sev-CycE; 3A; E; var; 3-93E; E2-promoter binding facto; E2F 1; E2F transcription factor 1; E2F-1; E2f-PA; E2f-PB; E2f-PC; E2F1; E2f1 E2F transcription factor 1; E2F1_HUMAN; Evar; 3; 164; KIAA4009; l; 3; 07172; l; 3; j3B1; l; 3; j3C2; l; 3; rM729; mKIAA4009; OTTHUMP00000030661; PBR3; PRB binding protein E2F 1; PRB-binding protein E2F-1; RBAP 1; RBAP-1; RBAP1; RBBP-3; RBBP3; RBP 3; RBP3; Retinoblastoma-associated protein 1; Retinoblastoma-binding protein 3; Transcription factor E2F1.	WB, ICC/IF, IP	Human, Rat
	E2F-1 Antibody (YA5305) is a mouse-derived and non-conjugated monoclonal antibody, targeting to E2F-1. It can be applicated for WB, ICC/IF, IP assays, in the background of human, rat.

HY-P85616

	eIF2α Antibody (YA5308) Dmel\CG6376; Dmel_CG6376; drosE2F1; E; Sev-CycE; 3A; E; var; 3-93E; E2-promoter binding facto; E2F 1; E2F transcription factor 1; E2F-1; E2f-PA; E2f-PB; E2f-PC; E2F1; E2f1 E2F transcription factor 1; E2F1_HUMAN; Evar; 3; 164; KIAA4009; l; 3; 07172; l; 3; j3B1; l; 3; j3C2; l; 3; rM729; mKIAA4009; OTTHUMP00000030661; PBR3; PRB binding protein E2F 1; PRB-binding protein E2F-1; RBAP 1; RBAP-1; RBAP1; RBBP-3; RBBP3; RBP 3; RBP3; Retinoblastoma-associated protein 1; Retinoblastoma-binding protein 3; Transcription factor E2F1.	WB, ICC/IF, IP	Human, Mouse, Rat
	eIF2α Antibody (YA5308) is a mouse-derived and non-conjugated monoclonal antibody, targeting to eIF2α. It can be applicated for WB, ICC/IF, IP assays, in the background of human, mouse, rat.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-RS16721

Tspo Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Tspo Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tspo gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS15177

TSPO Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
TSPO Human Pre-designed siRNA Set A contains three designed siRNAs for TSPO gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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