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Results for "

PBPs

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Penicillin-binding protein (PBP) (36) 5-HT Receptor (4) Androgen Receptor (1) Antibiotic (49) Apoptosis (1) Bacterial (66) Beta-lactamase (8) Cytochrome P450 (1) DNA/RNA Synthesis (1) Drug Metabolite (1) Endogenous Metabolite (1) ERK (1) Estrogen Receptor/ERR (1) Histamine Receptor (3) Interleukin Related (7) Isotope-Labeled Compounds (5) MEK (1) NF-κB (7) p38 MAPK (7) Parasite (1) Raf (1) Ras (1) Reference Standards (1) TGF-beta/Smad (1) TNF Receptor (7)
By Research Areas:	Cancer (20) Endocrinology (1) Infection (65) Inflammation/Immunology (8) Neurological Disease (4)

By Targets:

Penicillin-binding protein (PBP) (36)

5-HT Receptor (4)

Androgen Receptor (1)

Antibiotic (49)

Apoptosis (1)

Bacterial (66)

Beta-lactamase (8)

Cytochrome P450 (1)

DNA/RNA Synthesis (1)

Drug Metabolite (1)

Endogenous Metabolite (1)

ERK (1)

Estrogen Receptor/ERR (1)

Histamine Receptor (3)

Interleukin Related (7)

Isotope-Labeled Compounds (5)

MEK (1)

NF-κB (7)

p38 MAPK (7)

Parasite (1)

Raf (1)

Ras (1)

Reference Standards (1)

TGF-beta/Smad (1)

TNF Receptor (7)

By Research Areas:

Cancer (20)

Endocrinology (1)

Infection (65)

Inflammation/Immunology (8)

Neurological Disease (4)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Penicillin-binding protein (PBP)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1257

Cefmetazole sodium Sodium cefmetazole	Bacterial Antibiotic	Infection Cancer
Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .

HY-B1595

Cefmetazole CS 1170	Antibiotic Bacterial	Infection Cancer
Cefmetazole (CS 1170) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative and anaerobic bacteria. Cefmetazole binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .

HY-B0129

Aztreonam Maximum Cited Publications 10 Publications Verification SQ-26,776	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection Cancer
Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3).

HY-116519

LY173013	Bacterial	Infection
LY173013 is an antibacterial agent with a broad spectrum antibacterial activity. LY173013 binds to PBP 3 of E.coli and can be utilized in antibacterial research .

HY-Z7592

(E)-Cefodizime (E)-THR-221	Antibiotic Bacterial Penicillin-binding protein (PBP)	Infection
(E)-Cefodizime ((E)-THR-221) is an antibiotic. (E)-Cefodizime can selectively bind to penicillin-binding proteins (PBPs) and inhibit the synthesis of the bacterial cell wall, thereby exerting antibacterial activity. (E)-Cefodizime is promising for research of various bacterial infectious diseases, such as for preoperative infection prophylaxis .

HY-114913

Fenarimol EL 222	Androgen Receptor Bacterial	Infection Endocrinology
Fenarimol (EL 222) is a potent and orally active fungicide. Fenarimol also is a androgen receptor inhibitor with an IC₅₀ value of 19 µM. Fenarimol decreases the mRNA expression of PBP C3, ODC, IGF-1 .

HY-173197

PBP4-IN-1	Bacterial	Infection
PBP4-IN-1 (Compound 1) is an inhibitor of penicillin-binding protein 4 (PBP4) of Staphylococcus aureus. PBP4-IN-1 enhances the inhibitory activity of antibiotics against PBP2a-mediated methicillin-resistant Staphylococcus aureus (MRSA) by inhibiting the function of PBP4. PBP4-IN-1 can be used for the study of osteomyelitis caused by Staphylococcus aureus and for the study of reversing PBP4-mediated resistance to β-lactam antibiotics.

HY-B1257R

Cefmetazole (sodium) (Standard)	Bacterial Antibiotic	Infection Cancer
Cefmetazole (sodium) (Standard) is the analytical standard of Cefmetazole (sodium). This product is intended for research and analytical applications. Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .

HY-117736

Ro 09-1428	Penicillin-binding protein (PBP) Bacterial	Infection Inflammation/Immunology
Ro 09-1428 is a broad-spectrum parenteral cephalosporin. Ro 09-1428 has potent antibacterial activities against Pseudomonas aeruginosa and Acinetobacter caloaceticus, with MIC90s of 0.39 and 6.25 μg/mL, respectively, better than Ceftazidime (HY-B0593). Additionally, Ro 09-1428 shows high activity against Escherichia coli, Kkbsielia pneumoniae, Proteus mirabilis, P. aeruginosa, staphylococci, and more. Ro 09-1428 preferentially attacks PBP 3 for target in E. coli and P. aeruginosa, which is promising for research of septicemias and serious P. aeruginosa infections .

HY-P10825

p21PBP	DNA/RNA Synthesis	Cancer
p21PBP, a 20 amino-acid peptide, is an inhibitor of DNA replication. p21PBP specifically binds to purified proliferating cell nuclear antigen (PCNA) in tumour cell extracts. p21PBP is promising for research of cancers .

HY-129949

Aztreonam (lysine)	Antibiotic Bacterial	Infection Cancer
Aztreonam (lysine) is a monocyclic beta-lactam antibiotic, and has a very high affinity for penicillin-binding protein 3 (PBP-3). Aztreonam (lysine) is active against Gram-negative aerobic bacteria .

HY-B0129S

Aztreonam-d6 SQ-26,776-d₆	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Aztreonam-d₆ is deuterium labeled Aztreonam. Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3).

HY-B0129R

Aztreonam (Standard)	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection
Aztreonam (Standard) is the analytical standard of Aztreonam. This product is intended for research and analytical applications. Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3).

HY-120366

WCK-5153	Penicillin-binding protein (PBP) Beta-lactamase Bacterial	Infection
WCK-5153 is a Penicillin-Binding Protein 2 (PBP2) inhibitor with an IC₅₀ of 0.14 μg/ml (for P. aeruginosa PBP2) and acts as a β-lactam enhancer against Pseudomonas aeruginosa. WCK-5153 can be used in studies of multidrug-resistant (MDR) pathogens .

HY-19806A

Ceftolozane sulfate 1 Publications Verification CXA-101; FR264205	Bacterial	Infection
Ceftolozane (CXA-101) sulfate is an antipseudomonal cephalosporin. Ceftolozane binds to P. aeruginosa essential PBPs (1b, 1c, 2 and 3) with high affinity. Ceftolozane inhibits cell wall synthesis by binding the PBPs. Ceftolozane sulfate inhibits P. aeruginosa and Enterobacteriaceae .

HY-P1116

PBP10 1 Publications Verification	Bacterial	Infection Inflammation/Immunology
PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1 . PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects .

HY-P1116A

PBP10 TFA 1 Publications Verification	Bacterial	Infection Inflammation/Immunology
PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1 . PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects .

HY-139744

FPI-1465	Beta-lactamase Penicillin-binding protein (PBP) Bacterial	Infection
FPI-1465 acts a dual inhibitor of serine-β-Lactamases and Penicillin-binding proteins (PBPs).FPI-1465 inhibits PBP2 (IC₅₀=1.0 µg/mL). FPI-1465 exhibits activity against β-lactamase CTX-M-15 and OXA-48 with K_ds of 0.011 and 5.3 µM, respectively .

HY-126387

Moenomycin complex	Antibiotic Bacterial	Infection
Moenomycin complex is a potent transglycosylase inhibitor. Moenomycin complex inhibits bacterial growth by blocking the transglycosylase activity of class A penicillin-binding proteins (PBPs) .

HY-B0198S

Cefaclor-d5	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Cefaclor-d₅ is the deuterium labeled Cefaclor. Cefaclor is an effective antibiotic agent, and specifically binds to penicillin-binding protein 3 (PBP 3) .

HY-B0396

Tebipenem pivoxil L084	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection
Tebipenem pivoxil (L084) is an orally active antibiotic against a variety of pathogenic bacteria. Tebipenem pivoxil binds penicillin-binding protein (PBP), thereby inhibiting cell wall synthesis .

HY-120859A

Zidebactam sodium salt WCK-5107 sodium salt	Beta-lactamase Penicillin-binding protein (PBP) Bacterial	Infection
Zidebactam sodium salt (WCK-5107 sodium salt) is a potent β-lactamase inhibitor . Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC₅₀ of 0.26 μg/mL .

HY-120859

Zidebactam 5+ Cited Publications WCK-5107	Beta-lactamase Penicillin-binding protein (PBP) Bacterial	Infection
Zidebactam (WCK-5107) is a potent β-lactamase inhibitor . Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC₅₀ of 0.26 μg/mL .

HY-B0396A

Tebipenem pivoxil hydrochloride L084 hydrochloride	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection
Tebipenem pivoxil (L084) hydrochloride is an orally active antibiotic against a variety of pathogenic bacteria. Tebipenem pivoxil hydrochloride binds penicillin-binding protein (PBP), thereby inhibiting cell wall synthesis .

HY-B1596A

Ceftizoxime sodium 1 Publications Verification SKF-88373	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection
Ceftizoxime sodium (SKF-88373) is third generation cephalosporin effective against Gram-negative and Gram-positive bacteria. It binds penicillin-binding proteins (PBPs) and inhibits the bacterial cell wall synthesis.

HY-B1325

Cefuroxime axetil	Bacterial Antibiotic	Infection Inflammation/Immunology
Cefuroxime axetil is an orally effective broad-spectrum β-lactam antibiotic that targets bacterial penicillin-binding proteins (PBPs, such as PBP3 and PBP1). Cefuroxime axetil inhibits cell wall synthesis, leading to bacterial lysis and death, with a minimum inhibitory concentration (MIC) of 0.12-4 mg/L for non-typeable Haemophilus influenzae (NTHi). Cefuroxime axetil is hydrolyzed by esterase to the active ingredient Cefuroxime (HY-B1256A) after oral absorption. Topical administration of Cefuroxime via bioadhesive nanoparticles (BNPs) can prolong the drug's retention time in the middle ear (≥7 days). Cefuroxime axetil can be used in the study of otitis media (especially NTHi infection). Cefuroxime axetil can achieve precise antibacterial effects through oral or topical nano-delivery systems, reducing systemic exposure and the risk of antibiotic resistance .

HY-109008

Nacubactam 2 Publications Verification OP0595 free acid	Beta-lactamase Bacterial	Infection
Nacubactam (OP0595 free acid) is a potent non-β-lactam-β-lactamase inhibitor with activity against class A and C β-lactamases. Nacubactam acts as a penicillin binding protein (PBP) 2-active antibacterial, and gives β-lactamase-independent potentiation of β-lactams targeting other PBPs. Nacubactam potentiates the antimicrobial activities of Piperacillin (HY-B1923), Cefepime (HY-B0692), and Meropenem (HY-13678) against CTX-M-15-positive Escherichia coli and KPC-positive Klebsiella pneumoniae .

HY-121544A

Methicillin sodium hydrate	Penicillin-binding protein (PBP) Bacterial Antibiotic Histamine Receptor	Infection
Methicillin sodium hydrate is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin sodium hydrate is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins. Methicillin sodium hydrate can be used for the research of skin infections, osteomyelitis, and endocarditis .

HY-121544

Methicillin	Penicillin-binding protein (PBP) Bacterial Antibiotic Histamine Receptor	Infection
Methicillin is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins.Methicillin can be used for the research of skin infections, osteomyelitis, and endocarditis .

HY-114780

Lactivicin	Penicillin-binding protein (PBP) Bacterial	Infection
Lactivicin is a non-beta-lactam antibiotic showing beta-lactam action through binding to penicillin-binding protein (PBP). Lactivicin is moderately active against a wide range of Gram-negative bacteria and highly active against Gram-positive bacteria .

HY-120859R

Zidebactam (Standard)	Beta-lactamase Penicillin-binding protein (PBP) Bacterial	Infection
Zidebactam (Standard) is the analytical standard of Zidebactam. This product is intended for research and analytical applications. Zidebactam (WCK-5107) is a potent β-lactamase inhibitor . Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL .

HY-B0396R

Tebipenem pivoxil (Standard) L084 (Standard)	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection
Tebipenem pivoxil (Standard) is the analytical standard of Tebipenem pivoxil. This product is intended for research and analytical applications. Tebipenem pivoxil (L084) is an orally active antibiotic against a variety of pathogenic bacteria. Tebipenem pivoxil binds penicillin-binding protein (PBP), thereby inhibiting cell wall synthesis[1].

HY-B0198A

Cefaclor monohydrate 1 Publications Verification	Antibiotic Bacterial Penicillin-binding protein (PBP) 5-HT Receptor	Infection Neurological Disease Inflammation/Immunology
Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3). Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections .

HY-B0198

Cefaclor 1 Publications Verification	Antibiotic Penicillin-binding protein (PBP) Bacterial 5-HT Receptor	Infection Neurological Disease Inflammation/Immunology
Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3). Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections .

HY-139745A

FPI-1523	Beta-lactamase Bacterial	Infection
FPI-1523, a derivative of Avibactam, is a potent β-lactamase inhibitor, with K_ds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 also inhibits *PBP2, with an IC₅₀* of 3.2 μM. FPI-1523 exhibits considerable antimicrobial activity .

HY-150063

Antibacterial agent 116	Penicillin-binding protein (PBP) Bacterial	Infection
Antibacterial agent 116 is a benzophenone-containing salicylanilide compound. Antibacterial agent 116 has potent antibacterial activity by inhibiting the peptidoglycan formation. Antibacterial agent 116 is used as a photoaffinity probe to label Acinetobacter baumannii penicillin-binding protein (PBP1b), block the propagation pathway to disrupt the growth of peptidoglycan chain .

HY-139745

FPI-1523 sodium	Beta-lactamase Bacterial	Infection
FPI-1523 sodium, a derivative of Avibactam, is a potent β-lactamase inhibitor, with K_ds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 sodium also inhibits *PBP2, with an IC₅₀* of 3.2 μM. FPI-1523 sodium exhibits considerable antimicrobial activity .

HY-121544AR

Methicillin (sodium hydrate) (Standard)	Penicillin-binding protein (PBP) Bacterial Antibiotic Histamine Receptor	Infection
Methicillin (sodium hydrate) (Standard) is the analytical standard of Methicillin (sodium hydrate). This product is intended for research and analytical applications. Methicillin sodium hydrate is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin sodium hydrate is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins. Methicillin sodium hydrate can be used for the research of skin infections, osteomyelitis, and endocarditis .

HY-18719ER

Endoxifen (Standard)	Cytochrome P450 Estrogen Receptor/ERR Drug Metabolite Parasite	Cancer
Methicillin (sodium hydrate) (Standard) is the analytical standard of Methicillin (sodium hydrate). This product is intended for research and analytical applications. Methicillin sodium hydrate is a narrow-spectrum β-lactam antibiotic, acts by inhibiting penicillin-binding proteins (PBPs). Methicillin sodium hydrate is active against Staphylococcus aureus and Staphylococcus epidermidis that are resistant to other penicillins. Methicillin sodium hydrate can be used for the research of skin infections, osteomyelitis, and endocarditis .

HY-121329

Carumonam AMA-1080; Ro 17-2301	Penicillin-binding protein (PBP) Antibiotic Bacterial	Infection
Carumonam (AMA-1080; Ro 17-2301) is a sulfonated monocyclic β-Lactam Antibiotic, targeting to penicillin-binding protein (PBP). Carumonam exerts highly activity against Enterobacteriaceae, Pseudomonas aeruginosa, and Haemophilus influenzae, while it weakly and even inactively inhibits Streptococcus pneumoniae and Staphylococcus aureus. Carumonam is resistant to beta-lactamase-mediated hydrolysis .

HY-19071

BK-218	Antibiotic Bacterial	Infection
BK-218 is an orally active cephalosporin antibiotic that binds to penicillin-binding proteins (PBPs) and has a greater inhibitory effect than Cephalexin (HY-B0200) and Cefoxitin (HY-B1825). BK-218 has similar antibacterial activity to Cefamandole (HY-B1128) and can be used in the development of antibacterial drugs .

HY-106922

Sanfetrinem GV104326	Antibiotic Bacterial	Infection
Sanfetrinem (GV104326) is a β-lactamase-stable antibiotic. Sanfetrinem has broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria .

HY-B0198R

Cefaclor (Standard)	Antibiotic Penicillin-binding protein (PBP) Bacterial 5-HT Receptor	Infection Neurological Disease Inflammation/Immunology
Cefaclor (Standard) is the analytical standard of Cefaclor. This product is intended for research and analytical applications. Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3). Cefaclor can be used for the research kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections .

HY-B0200

Cephalexin 5+ Cited Publications Cefalexin; Cephacillin	Penicillin-binding protein (PBP) Antibiotic Bacterial	Infection Cancer
Cephalexin (Cefalexin) is a potent, orally active semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al .

HY-D0184R

2'-Deoxycytidine (Standard)	Endogenous Metabolite	Cancer
Cefaclor (monohydrate) (Standard) is the analytical standard of Cefaclor (monohydrate). This product is intended for research and analytical applications. Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3). Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections .

HY-13588

Cefsulodin sodium SCE-129 sodium	Bacterial Antibiotic	Infection
Cefsulodin (SCE-129) sodium is a third generation β lactam antibiotic and member of the cephems subgroup of antibiotics. Cefsulodin sodium inhibits cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) cross-linking and transpeptidation of peptidogly. Cefsulodin sodium is a potent tyrosine phosphatase inhibitor against mPTPB, a virulent phosphatase from Mycobacterium tuberculosis, with an IC₅₀ value of 16 μM .

HY-B0198AR

Cefaclor (monohydrate) (Standard)	Antibiotic Bacterial Penicillin-binding protein (PBP) 5-HT Receptor	Infection Neurological Disease Inflammation/Immunology
Cefaclor (monohydrate) (Standard) is the analytical standard of Cefaclor (monohydrate). This product is intended for research and analytical applications. Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3). Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections .

HY-13588B

Cefsulodin sodium hydrate SCE-129 sodium hydrate	Antibiotic Bacterial	Infection
Cefsulodin (SCE-129) sodium is a third generation β lactam antibiotic and member of the cephems subgroup of antibiotics. Cefsulodin sodium inhibits cell wall synthesis by competitively inhibiting penicillin binding protein (PBP) cross-linking and transpeptidation of peptidogly. Cefsulodin sodium is a potent tyrosine phosphatase inhibitor against mPTPB, a virulent phosphatase from Mycobacterium tuberculosis, with an IC₅₀ value of 16 μM .

HY-B0200A

Cephalexin hydrochloride 5+ Cited Publications Cefalexin hydrochloride; Cephacillin hydrochloride	Penicillin-binding protein (PBP) Bacterial Antibiotic	Infection Cancer
Cephalexin (Cefalexin) hydrochloride is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin (Cefalexin) hydrochloride has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) hydrochloride targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin (Cefalexin) hydrochloride is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al .

HY-B0200C

Cephalexin hydrochloride monohydrate Cefalexin hydrochloride monohydrate; Cephacillin hydrochloride monohydrate	Penicillin-binding protein (PBP) Antibiotic Bacterial	Infection Cancer
Cephalexin (Cefalexin) hydrochloride monohydrate is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin (Cefalexin) hydrochloride monohydrate has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) hydrochloride monohydrate targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin (Cefalexin) hydrochloride monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al .

Cat. No.	Product Name	Target	Research Area

HY-P1116

PBP10 1 Publications Verification	Bacterial	Infection Inflammation/Immunology
PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1 . PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects .

HY-P1116A

PBP10 TFA 1 Publications Verification	Bacterial	Infection Inflammation/Immunology
PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1 . PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects .

HY-P10825

p21PBP	DNA/RNA Synthesis	Cancer
p21PBP, a 20 amino-acid peptide, is an inhibitor of DNA replication. p21PBP specifically binds to purified proliferating cell nuclear antigen (PCNA) in tumour cell extracts. p21PBP is promising for research of cancers .

Cat. No.	Product Name	Target	Research Area

HY-P99537

Ulenistamab PBP1510	Inhibitory Antibodies	Cancer
Ulenistamab (PBP1510) is a first-in-class hunamised IgG1 monoclonal antibody targeting pancreatic adenocarcinoma upregulated factor (PAUF). Ulenistamab can be used for pancreatic cancer (PC) research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-D0184R

2'-Deoxycytidine (Standard)	Structural Classification Natural Products Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
Cefaclor (monohydrate) (Standard) is the analytical standard of Cefaclor (monohydrate). This product is intended for research and analytical applications. Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3). Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections .

Cat. No.	Product Name	Chemical Structure

HY-B0129S

Aztreonam-d6
Aztreonam-d₆ is deuterium labeled Aztreonam. Aztreonam (SQ-26,776) is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3).

HY-W653936

Cephalexin-d5 hydrate

Cephalexin-d₅ (hydrate) is deuterium labeled Cephalexin (monohydrate). Cephalexin (Cefalexin) monohydrate is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin (Cefalexin) monohydrate has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) monohydrate targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin (Cefalexin) monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al .

HY-B0198S

Cefaclor-d5
Cefaclor-d₅ is the deuterium labeled Cefaclor. Cefaclor is an effective antibiotic agent, and specifically binds to penicillin-binding protein 3 (PBP 3) .

HY-N7101S1

Cefpodoxime Proxetil-d6

Cefpodoxime Proxetil-d₆ (U-76,252-d₆) is deuterium labeled Cefpodoxime Proxetil. Cefpodoxime proxetil is an orally administered broad spectrum third-generation cephalosporin. Cefpodoxime proxetil has anti-bacterial activity. Cefpodoxime proxetil binds to penicillin binding proteins (PBPs) which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis .

HY-B0898S

Ceftiofur-d3 sodium

Ceftiofur-d₃ sodium is deuterium labeled Ceftiofur sodium (HY-B0898). Ceftiofur sodium is a cell wall synthesis inhibitor that targets bacterial penicillin-binding proteins (PBPs) and has anti-inflammatory effects in endotoxemia. Ceftiofur sodium exerts bactericidal effects by inhibiting the synthesis of bacterial cell wall peptidoglycan, leading to bacterial cell lysis. Ceftiofur sodium also inhibits the activation of NF-κB and MAPKs, thereby reducing the secretion of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6 .

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