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Isoforms Recommended: PAK2
Results for "

PAK2

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

2

Recombinant Proteins

2

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-131043
    NVS-PAK1-C
    1 Publications Verification

    		 PAK Cancer
    NVS-PAK1-C is a potent, ATP-competitive and specific allosteric PAK1 inhibitor probe with IC50 values of 5 nM and 6 nM for dephosphorylated PAK1 and phosphorylated PAK1, respectively. NVS-PAK1-C is also against dephosphorylated PAK2 (IC50=270 nM) and phosphorylated PAK2 (IC50=720 nM) .
    NVS-PAK1-C
  • HY-19538
    FRAX1036
    4 Publications Verification

    		 PAK Cancer
    FRAX1036 is a PAK inhibitor with Kis of 23.3 nM, 72.4 nM, and 2.4 μM for PAK1, PAK2 and PAK4, respectively.
    FRAX1036
  • HY-15542B
    FRAX486
    Maximum Cited Publications
    10 Publications Verification

    		 PAK Cancer
    FRAX486 is a p21-activated kinase (PAK) inhibitor with IC50s of 14, 33 and 39 nM for PAK1, PAK2 and PAK3, respectively.
    FRAX486
  • HY-19635
    G-5555
    5+ Cited Publications

    		 PAK Cancer
    G-5555 is a potent p21-activated kinase 1 (PAK1) inhibitor with Kis of 3.7 nM and 11 nM for PAK1 and PAK2, respectively.
    G-5555
  • HY-139253
    MRIA9

    		Salt-inducible Kinase (SIK) PAK Apoptosis Cancer
    MRIA9 is an ATP-competitive, pan Salt-Inducible kinase (SIK) and PAK2/3 inhibitor, with IC50 values of 516 nM, 180 nM and 127 nM for SIK1, SIK2 and SIK3, respectively .
    MRIA9
  • HY-120940A
    AZ13705339 hemihydrate

    		PAK Cancer
    AZ13705339 hemihydrate is a highly potent and selective PAK1 inhibitor with IC50s of 0.33 nM and 59 nM for PAK1 and pPAK1, respectively. AZ13705339 hemihydrate has binding affinities to PAK1 and PAK2, with Kds of 0.28 nM and 0.32 nM, respectively. AZ13705339 hemihydrate can be used in the research of cancers .
    AZ13705339 hemihydrate
  • HY-RS09989
    PAK2 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) PAK Others

    PAK2 Rat Pre-designed siRNA Set A contains three designed siRNAs for PAK2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PAK2 Rat Pre-designed siRNA Set A
    PAK2 Rat Pre-designed siRNA Set A
  • HY-RS09988
    Pak2 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) PAK Others

    Pak2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pak2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Pak2 Mouse Pre-designed siRNA Set A
    Pak2 Mouse Pre-designed siRNA Set A
  • HY-RS09987
    PAK2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) PAK Others

    PAK2 Human Pre-designed siRNA Set A contains three designed siRNAs for PAK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PAK2 Human Pre-designed siRNA Set A
    PAK2 Human Pre-designed siRNA Set A
  • HY-116917
    G-9791

    		PAK Cancer
    G-9791, a poyridone side chain analogue, is a potent PAK inhibitor with Ki values of 0.95 nM and 2.0 nM for PAK1 and PAK2, respectively .
    G-9791
  • HY-120940
    AZ13705339

    		PAK Cancer
    AZ13705339 is a highly potent and selective PAK1 inhibitor with IC50s of 0.33 nM and 59 nM for PAK1 and pPAK1, respectively. AZ13705339 has binding affinities to PAK1 and PAK2, with Kds of 0.28 nM and 0.32 nM, respectively. AZ13705339 can be used in the research of cancers .
    AZ13705339
  • HY-171034
    PQA-18

    		Interleukin Related TNF Receptor PAK Inflammation/Immunology
    PQA-18 is a unique PAK2 inhibitor (IC50: 10 nM). PQA-18 has immunosuppressing effects. PQA-18 suppresses IL2, IL4, IL6, and TNFα. PQA-18 inhibits the population of a subset of regulatory T cells and the immunoglobulin (Ig) production against T cell-dependent antigens as well as alleviates dermatitis in mice .
    PQA-18
  • HY-146786
    ZMF-10

    		PAK Apoptosis Cancer
    ZMF-10 is a highly potent PAK1 inhibitor, with IC50s of 174 nM, 1.038 μM and 1.372 μM for PAK1, PAK2 and PAK3, respectively. ZMF-10 can inhibit PAK1 activity to affect PAK1-regulated apoptosis, ER-Stress and migration in MDA-MB-231 cells. ZMF-10 can be used for researching anticancer .
    ZMF-10

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