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Omega-6 Fatty Acid

" in MedChemExpress (MCE) Product Catalog:

30

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1

Biochemical Assay Reagents

8

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2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-109590A
    Arachidonic acid sodium salt
    Maximum Cited Publications
    39 Publications Verification

    Immunocytophyt sodium salt

    Endogenous Metabolite Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Arachidonic acid (Immunocytophyt) sodium salt is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid sodium salt also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid sodium salt improves cognitive response and cardiovascular function .
    Arachidonic acid sodium salt
  • HY-109590
    Arachidonic acid
    Maximum Cited Publications
    39 Publications Verification

    Immunocytophyt

    Endogenous Metabolite Cardiovascular Disease Inflammation/Immunology
    Arachidonic acid (Immunocytophyt) is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid improves cognitive response and cardiovascular function .
    Arachidonic acid
  • HY-109590S3

    Immunocytophyt-13C4

    Isotope-Labeled Compounds Endogenous Metabolite Cardiovascular Disease Inflammation/Immunology
    Arachidonic acid- 13C4 (Immunocytophyt- 13C4) is 13C labeled Arachidonic acid. Arachidonic acid (Immunocytophyt) is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid improves cognitive response and cardiovascular function .
    Arachidonic acid-13C4
  • HY-W071746
    Linolelaidic acid
    1 Publications Verification

    Linoelaidic Acid

    Endogenous Metabolite Parasite Apoptosis Infection Inflammation/Immunology
    Linolelaidic acid (Linoelaidic acid) is an omega-6 trans fatty acid (TFA) that is an essential nutrient with oral activity. Linolelaidic acid can be added to enteral nutrition (oral), parenteral nutrition (intravenous), and infant formula. Linolelaidic acid has anti-inflammatory and anti-parasitic ((Parasite)) activities, and can induce Apoptosis. Linolelaidic acid is useful for research in infections .
    Linolelaidic acid
  • HY-N7864

    all-cis-4,7,10,13,16-Docosapentaenoic Acid

    Biochemical Assay Reagents Others
    Docosapentaenoic acid (DPA) is a 22-carbon fatty acid found in fish oil. It is a minor component of total serum unsaturated fatty acids in humans, ranging from 0.1% to 1%, and increasing with dietary supplementation. all-cis-4,7,10,13,16-DPA, also known as Austrian acid, is an isomer of DPA. It is an omega-6 fatty acid formed by the extension and desaturation of arachidonic acid. During fatty acid desaturase syndrome, levels of this fatty acid may be reduced, which may affect development. Upregulated hepatic elongate expression of very long fatty acid protein 6 and elevated levels of very long chain fatty acids, including all-cis 4,7,10,13,16-DPA, are characteristic of nonalcoholic steatohepatitis, a precancerous disease of hepatocellular carcinoma.
    Osbond acid
  • HY-N7140R

    γ-Linolenic Acid (Standard)

    Reference Standards Endogenous Metabolite Metabolic Disease
    Gamma-Linolenic acid (Standard) is the analytical standard of Gamma-Linolenic acid. This product is intended for research and analytical applications. Gamma-linolenic acid (γ-Linolenic acid) is an omega-6 (n-6), 18 carbon (18C-) polyunsaturated fatty acid (PUFA) extracted from Perilla frutescens. Gamma-linolenic acid supplements could restore needed PUFAs and mitigate the disease .
    Gamma-Linolenic acid (Standard)
  • HY-W071746R

    Linoelaidic Acid (Standard)

    Reference Standards Endogenous Metabolite Parasite Apoptosis Infection Inflammation/Immunology
    Linolelaidic acid (Standard) is the analytical standard of Linolelaidic acid. This product is intended for research and analytical applications. Linolelaidic acid (Linoelaidic acid) is an omega-6 trans fatty acid (TFA) that is an essential nutrient with oral activity. Linolelaidic acid can be added to enteral nutrition (oral), parenteral nutrition (intravenous), and infant formula. Linolelaidic acid has anti-inflammatory and anti-parasitic ((Parasite)) activities, and can induce Apoptosis. Linolelaidic acid is useful for research in infections[1][2][3].
    Linolelaidic acid (Standard)
  • HY-145504

    1,2-Palmitin-3-Linoelaidin

    Biochemical Assay Reagents Metabolic Disease
    12-Dipalmitoyl-3-Linoelaidoyl-rac-glycerol is a triacylglycerol containing palmitic acid (HY-N0830) at the sn-1 and sn-2 positions and linoelaidic acid (HY-W071746) at the sn-3 position. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. Linolelaidic acid, an omega-6 trans fatty acid, acts as a source of energy. Linolelaidic acid is an essential nutrient, adding in enteral, parenteral, and infant formulas. Linolelaidic acid can be used for heart diseases research .
    12-Dipalmitoyl-3-Linoelaidoyl-rac-glycerol
  • HY-169030

    Biochemical Assay Reagents Metabolic Disease
    Diarachidonin is a diacylglycerol that contains the ω-6 polyunsaturated 20-carbon fatty acid Arachidic acid (HY-W004260).
    Diarachidonin
  • HY-169033

    Biochemical Assay Reagents Metabolic Disease
    Di-γ-linolenin is a diacylglycerol that contains the ω-6 fatty acid Gamma-Linolenic acid (HY-N7140).
    Di-γ-linolenin
  • HY-W718405

    Endogenous Metabolite Others
    (5Z,14Z)-5,14-Eicosadienoic acid is a ω-6 C20:2 fatty acid .
    (5Z,14Z)-5,14-Eicosadienoic acid
  • HY-114610

    Endogenous Metabolite Free Fatty Acid Receptor Metabolic Disease
    13Z,16Z-Docosadienoic acid, a ω-6 polyunsaturated fatty acid, possesses anti-borreliae effect. 13Z,16Z-Docosadienoic acid, as a long-chain fatty acid (LCFA), is a free fatty acid receptor 4 (FFAR4 or GPR120, a LCFA receptor) agonist .
    13Z,16Z-Docosadienoic acid
  • HY-145521

    5(S)-Hydroxy-6E,8Z,11Z-eicosatrienoic Acid

    Endogenous Metabolite Cardiovascular Disease
    5(S)-HETrE is a metabolite of the ω-6 fatty acid γ-linolenic acid. 5(S)-HETrE can be elevated in serum levels in an obesity mouse model .
    5(S)-HETrE
  • HY-116722

    Reactive Oxygen Species (ROS) Inflammation/Immunology
    (2E)-4-Hydroperoxy-2-nonenal is a lipid peroxidation product derived from oxidized ω-6 polyunsaturated fatty acids, and can be used as a marker of oxidative stress .
    (2E)-4-Hydroperoxy-2-nonenal
  • HY-CE00069

    C28:4(Omega-6)-CoA

    Biochemical Assay Reagents Others
    (13Z,16Z,19Z,22Z)-Octacosatetraenoyl-CoA (C28:4(Omega-6)-CoA) is an unsaturated fatty acyl-CoA.
    (13Z,16Z,19Z,22Z)-Octacosatetraenoyl-CoA
  • HY-CE00012

    C26:4(Omega-6)-CoA

    Biochemical Assay Reagents Others
    (11Z,14Z,17Z,20Z)-Hexacosatetraenoyl-CoA (C26:4(Omega-6)-CoA) is an unsaturated fatty acyl-CoA.
    (11Z,14Z,17Z,20Z)-Hexacosatetraenoyl-CoA
  • HY-A0143
    Dihomo-γ-linolenic acid
    4 Publications Verification

    DGLA; all-cis-8,11,14-Eicosatrienoic Acid

    Endogenous Metabolite Cardiovascular Disease Inflammation/Immunology Cancer
    Dihomo-γ-linolenic acid (DGLA) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system .
    Dihomo-γ-linolenic acid
  • HY-CE00093

    C32:5(Omega-6)-CoA

    Biochemical Assay Reagents Others
    (14Z,17Z,20Z,23Z,26Z)-Dotriacontapentaenoyl-CoA (C32:5(Omega-6)-CoA) is an unsaturated fatty acyl-CoA.
    (14Z,17Z,20Z,23Z,26Z)-Dotriacontapentaenoyl-CoA
  • HY-CE00067

    3-Oxo-C28:4(Omega-6)-CoA

    Biochemical Assay Reagents Others
    (13Z,16Z,19Z,22Z)-3-Oxooctacosatetraenoyl-CoA (3-Oxo-C28:4(omega-6)-CoA) is an unsaturated fatty acyl-CoA.
    (13Z,16Z,19Z,22Z)-3-Oxooctacosatetraenoyl-CoA
  • HY-170697

    Drug Metabolite Neurological Disease
    4(Z),7(Z),10(Z),13(Z),16(Z)-N-(2-hydroxyethyl)-Docosapentaenamide is a long-chain ω-6 fatty acid with a hydroxyethylamide group attached at the alpha chain.
    4(Z),7(Z),10(Z),13(Z),16(Z)-N-(2-Hydroxyethyl)-docosapentaenamide
  • HY-A0143A
    Dihomo-γ-linolenic acid sodium
    4 Publications Verification

    DGLA sodium; all-cis-8,11,14-Eicosatrienoic Acid sodium

    Endogenous Metabolite Cardiovascular Disease Inflammation/Immunology Cancer
    Dihomo-γ-linolenic acid (DGLA; all-cis-8,11,14-Eicosatrienoic acid) sodium is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid (sodium) attenuates atherosclerosis in the apolipoprotein E deficient mouse model system .
    Dihomo-γ-linolenic acid sodium
  • HY-W009276

    Methyl GLA

    Apoptosis Cancer
    γ-Linolenic Acid methyl ester (Methyl GLA) is an esterified version of γ-Linolenic Acid (GLA), which is an ω-6 fatty acid, serves as melanoma cell proliferation inhibitors. γ-Linolenic Acid methyl ester inhibits ADP-induced blood platelet aggregation and induces apoptosis .
    γ-Linolenic Acid methyl ester
  • HY-A0143S

    DGLA-d6; all-cis-8,11,14-Eicosatrienoic Acid-d6

    Endogenous Metabolite Cardiovascular Disease Inflammation/Immunology Cancer
    Dihomo-γ-linolenic acid-d6 (DGLA-d6) is the deuterium labeled Dihomo-γ-linolenic acid. Dihomo-γ-linolenic acid (all-cis-8,11,14-Eicosatrienoic acid) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system .
    Dihomo-γ-linolenic acid-d6
  • HY-W009276R

    Methyl GLA (Standard)

    Reference Standards Apoptosis Cancer
    γ-Linolenic Acid methyl ester (Standard) is the analytical standard of γ-Linolenic Acid methyl ester. This product is intended for research and analytical applications. γ-Linolenic Acid methyl ester (Methyl GLA) is an esterified version of γ-Linolenic Acid (GLA), which is an ω-6 fatty acid, serves as melanoma cell proliferation inhibitors. γ-Linolenic Acid methyl ester inhibits ADP-induced blood platelet aggregation and induces apoptosis .
    γ-Linolenic Acid methyl ester (Standard)
  • HY-W753927

    C18:2(9E,12Z); C18:2 n-6

    Endogenous Metabolite Metabolic Disease
    9(E),12(Z)-Octadecadienoic acid is an ω-6 polyunsaturated fatty acid and an isomer of linoleic acid (HY-N0729) that contains a trans double bond at the C9 position. It has been found as a minor component of bovine milk fat and in partially hydrogenated vegetable oils. 9(E),12(Z)-Octadecadienoic acid levels increase in rabbit meat following supplementation with heated sunflower oil, α-tocopheryl acetate, and zinc.
    9(Z)​,​12(E)​-​Octadecadienoic Acid
  • HY-19996
    AH-7614
    5 Publications Verification

    Free Fatty Acid Receptor Metabolic Disease
    AH-7614 is a potent and selective FFA4 (GPR120) antagonist, with pIC50s of 7.1, 8.1, and 8.1 for human, mouse, and rat FFA4, respectively. AH-7614 has selectivity for FFA4 over FFA1 (pIC50<4.6). AH-7614 is able to block effects of both the polyunsaturated ω-6 fatty acid linoleic acid and the synthetic FFA4 agonist .
    AH-7614
  • HY-116538

    trans-10,cis-12 CLA2

    Endogenous Metabolite PPAR NF-κB Stearoyl-CoA Desaturase (SCD) Lipase Metabolic Disease Inflammation/Immunology Cancer
    (10E,12Z)-Octadeca-10,12-dienoic acid (trans-10,cis-12 CLA2) is an orally active PPARα activator and inhibits adipocyte differentiation. (10E,12Z)-Octadeca-10,12-dienoic acid and its downstream metabolites have various antioxidant and antitumor activities. (10E,12Z)-Octadeca-10,12-dienoic acid can induce proinflammatory cytokines and chemokines, which would lead to decreased adipogenesis and insulin resistance in adipose tissue. (10E,12Z)-Octadeca-10,12-dienoic acid can affect many aspects of milk fat synthesis. (10E,12Z)-Octadeca-10,12-dienoic acid reduces expression of lipogenic enzymes and inhibits the desaturation of fatty acids. (10E,12Z)-Octadeca-10,12-dienoic acid can reduce lipoprotein lipase (LPL) activity in cultured 3T3-L1 adipocytes and enhance triacylglycerol release from these cells. (10E,12Z)-Octadeca-10,12-dienoic acid decreases the expression of hepatic stearoyl-CoA desatyrase mRNA in mice. (10E,12Z)-Octadeca-10,12-dienoic acid is associated with changes in mucosal NF-κB and Cyclin D1 protein levels in mice .
    (10E,12Z)-Octadeca-10,12-dienoic acid
  • HY-N0729
    Linoleic acid
    10+ Cited Publications

    Endogenous Metabolite Cardiovascular Disease Metabolic Disease Cancer
    Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism .
    Linoleic acid
  • HY-141635

    Endogenous Metabolite Metabolic Disease
    cis-11,14-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid, a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic acid competitively inhibits inosine 5’-monophosphate dehydrogenase (Ki=3.1 μM) and inhibits the binding of LTB4 to its receptor on neutrophils (Ki=3.0 μM). Also, serum levels of eicosadienoic acids negatively correlate with degree of sleep disturbance.3 Eicosadienoic acids are converted by desaturases, in vivo, to eicosatrienoic acids, which are potent vasodilators.
    cis-11,14-Eicosadienoic acid methyl ester
  • HY-136410

    Endogenous Metabolite Metabolic Disease
    4-hydroxy Nonenal Mercapturic Acid (4-HNE) is generated by the peroxidation of common ω-6 polyunsaturated fatty acids (PUFAs) such as linoleic acid, DGLA, and arachidonic acid. 4-hydroxy Nonenal Mercapturic Acid is rapidly cleared from plasma and enters the enterohepatic circulation in rats as a glutathione conjugate. Approximately two-thirds of 4-hydroxy Nonenal Mercapturic Acid is excreted in the urine within 48 hours, primarily as mercapturic acid conjugates. Approximately half of the metabolites are C-1 aldehydes of 4-hydroxy Nonenal Mercapturic Acid that are reduced to alcohols. The remainder are C-1 aldehydes or have been oxidized to C-1 carboxylic acids. These aldehydes and carboxylic acids can also form gamma-lactols and gamma-lactones, respectively, resulting in at least four or five final urinary metabolites of 4-HNE in vivo.
    4-hydroxy Nonenal Mercapturic Acid

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