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Results for "

O-glycan

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

8

Biochemical Assay Reagents

1

MCE Kits

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-E70568
    Protease (O-glycan Cleaving)

    		Ser/Thr Protease Others
    Protease (O-glycan Cleaving) is recombinantly expressed from E.coli and contains a His tag. Protease (O-glycan Cleaving) is an O-glycan-dependent protease that digests proteins carrying mucin-type O-glycans, including sialylated substrates, glycosylated Ser and Thr residues at the N terminus. Protease (O-glycan Cleaving) digests a variety of O-glycan structures, including sialylated glycosylated core 1 and core 2 structures and Tn antigen. Protease (O-glycan Cleaving) does not digest terminally modified serine or threonine residues, nor does it digest N-glycosylation sites on glycoproteins.
    Protease (O-glycan Cleaving)
  • HY-158469
    Disialylated Core 1 O-glycan (C1S(3,6)2), 2-AB labelled

    		Biochemical Assay Reagents Others
    Disialylated Core 1 O-glycan (C1S(3,6)2), 2-AB labeled is a disialylated, 2-AB (2-aminobenzamide) labeled O-linked glycan with core structure 1 (MUC1-M). Disialylated Core 1 O-glycan (C1S(3,6)2), 2-AB labeled is related to sialylation and participates in life activities including cell recognition, protection, immune regulation and disease markers .
    Disialylated Core 1 O-glycan (C1S(3,6)2), 2-AB labelled
  • HY-160109
    Ac5GalNTGc
    1 Publications Verification

    		 Mucin Inflammation/Immunology Cancer
    Ac5GalNTGc is a potent, peracetylated C-2 thioglycolyl-substituted GalNAc analog that efficiently inhibits mucin-type O-glycan biosynthesis. Ac5GalNTGc reduces leukocyte sialyl-Lewis-X expression and inhibits L-/P-selectin mediated rolling under flow, as well as P-selectin dependent leukocyte-platelet adhesion. Ac5GalNTGc exhibits anti-inflammatory activity in a thioglycollate-induced acute peritonitis model. Ac5GalNTGc can be used for studies of O-glycan/mucin biology, inflammation, and related translational research .
    Ac5GalNTGc
  • HY-160109A
    Ac5GalNTGc epimer

    		Mucin Inflammation/Immunology
    Ac5GalNTGc epimer is an analogue of hexosamine and the racemate of Ac5GalNTGc (HY-160109). Ac5GalNTGc is a potent, peracetylated C-2 thioglycolyl-substituted GalNAc analog that efficiently inhibits mucin-type O-glycan biosynthesis. Ac5GalNTGc reduces leukocyte sialyl-Lewis-X expression and inhibits L-/P-selectin mediated rolling under flow, as well as P-selectin dependent leukocyte-platelet adhesion. Ac5GalNTGc exhibits anti-inflammatory activity in a thioglycollate-induced acute peritonitis model. Ac5GalNTGc can be used for studies of O-glycan/mucin biology, inflammation, and related translational research .
    Ac5GalNTGc epimer
  • HY-158471
    Core 1 O-glycan (C1)

    		Biochemical Assay Reagents Others
    Core 1 O-glycan (C1) is an important O-linked glycan with core structure 1 (MUC1-M). Core 1 O-glycan (C1), 2AB labeled is related to sialylation and participates in life activities including cell recognition, protection, immune regulation and disease markers .
    Core 1 O-glycan (C1)
  • HY-158467
    Core 1 O-glycan (C1), 2AB labelled

    		Biochemical Assay Reagents Others
    Core 1 O-glycan (C1), 2AB labeled is a 2AB (2-aminobenzamide) labeled O-linked glycan with core structure 1 (MUC1-M). Core 1 O-glycan (C1), 2AB labeled is related to sialylation and participates in life activities including cell recognition, protection, immune regulation and disease markers .
    Core 1 O-glycan (C1), 2AB labelled
  • HY-158472
    Sialylated Core 1 O-glycan (C1S(3)1)

    		Biochemical Assay Reagents Others
    Sialylated Core 1 O-glycan (C1S(3)1) () is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .
    Sialylated Core 1 O-glycan (C1S(3)1)
  • HY-158470
    Disialylated Core 2 O-glycan (C2S(3,3)2), 2-AB labelled

    		Biochemical Assay Reagents Others
    Disialylated Core 2 O-glycan (C2S(3,3)2), 2-AB labeled is a 2-AB (2-aminobenzamide) labeled O-linked glycan with core structure 2. Disialylated Core 2 O-glycan (C2S(3,3)2), 2-AB labeled is related to sialylation and participates in life activities including cell recognition, protection, immune regulation and disease markers .
    Disialylated Core 2 O-glycan (C2S(3,3)2), 2-AB labelled
  • HY-158468
    Sialylated Core 1 O-glycan (C1S(3)1), 2AB labelled

    		Biochemical Assay Reagents Others
    Sialylated Core 1 O-glycan (C1S(3)1), 2AB labelled () is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .
    Sialylated Core 1 O-glycan (C1S(3)1), 2AB labelled
  • HY-E70140
    α-1,4-N-Acetylglucosaminyltransferase 4

    EC 2.4.1; A4GNT

    		 Antibiotic Infection
    α-1,4-N-Acetylglucosaminyltransferase 4 (EC 2.4.1, A4GNT) catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans and suppresses H. pylori growth .
    α-1,4-N-Acetylglucosaminyltransferase 4

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