2. Search Result
Search Result
Results for "

Nirmatrelvir

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-138687
    Nirmatrelvir
    75+ Cited Publications

    PF-07321332

    		 SARS-CoV Infection Inflammation/Immunology
    Nirmatrelvir (PF-07321332) is a potent and orally active SARS-CoV 3C-like protease (3CL PRO) inhibitor. Nirmatrelvir (PF-07321332) targets to the SARS-CoV-2 virus and can be used for COVID-19 research .
    Nirmatrelvir
  • HY-138687R
    Nirmatrelvir (Standard)

    		SARS-CoV Infection Inflammation/Immunology
    Nirmatrelvir (Standard) is the analytical standard of Nirmatrelvir. This product is intended for research and analytical applications. Nirmatrelvir (PF-07321332) is a potent and orally active SARS-CoV 3C-like protease (3CL PRO) inhibitor. Nirmatrelvir (PF-07321332) targets to the SARS-CoV-2 virus and can be used for COVID-19 research .
    Nirmatrelvir (Standard)
  • HY-138687S
    Nirmatrelvir-d9

    PF-07321332-d9

    		 Isotope-Labeled Compounds Others
    Nirmatrelvir-d9 (PF-07321332-d9) is the deuterium labeled Nirmatrelvir (HY-138687) .
    Nirmatrelvir-d9
  • HY-171164
    Nirmatrelvir analog-1

    		Drug Intermediate Infection
    Nirmatrelvir analog-1 (Compound 234) is an analog of Nirmatrelvir (HY-138687). Nirmatrelvir analog-1 can be used as drug intermediate for synthesis of cysteine protease .
    Nirmatrelvir analog-1
  • HY-138687S1
    Nirmatrelvir-d6

    PF-07321332-d6

    		 Isotope-Labeled Compounds SARS-CoV Infection Inflammation/Immunology
    Nirmatrelvir-d6 (PF-07321332-d6) is deuterium labeled Nirmatrelvir. Nirmatrelvir (PF-07321332) is a potent and orally active SARS-CoV 3C-like protease (3CL PRO) inhibitor. Nirmatrelvir (PF-07321332) targets to the SARS-CoV-2 virus and can be used for COVID-19 research .
    Nirmatrelvir-d6
  • HY-176440
    BP-198

    		Virus Protease SARS-CoV PROTACs Infection
    BP-198 is an Mpro PROTAC degrader. BP-198 promotes the ubiquitination and degradation of Mpro. BP-198 has antiviral effects against SARS-CoV-2 (IC50: 11.8 μM) and has stronger activity against drug-resistant viruses. (Pink: target protein ligand (HY-176442); blue: E3 ligase ligand (HY-176441); black: linker (HY-W457968); E3 ligase-linker conjugate (HY-176443)) .
    BP-198
  • HY-169224
    SARS-CoV-2-IN-100

    		SARS-CoV Infection
    SARS-CoV-2-IN-100 (Compound 172) is an inhibitor of SARS-CoV-2, demonstrating broad-spectrum antiviral activity against various SARS-CoV-2 variants. SARS-CoV-2-IN-100 exhibits synergistic effects with Nirmatrelvir, which can reduce the risk of antiviral drug resistance .
    SARS-CoV-2-IN-100
  • HY-168916
    Jun13296

    		SARS-CoV Virus Protease
    Jun13296 is an orally active quinoline SARS-CoV-2 papain-like protease inhibitor (IC50 = 0.13  µM, Ki  = 8.8  nM). Jun13296 exhibits potent inhibition against SARS-CoV-2 variants and Nirmatrelvir (HY-138687)-resistant mutants. Jun13296 improves lung viral titers, and prevents lung tissue damage in a SARS-CoV-2 infection model .
    Jun13296
  • HY-162464
    MPD2

    		PROTACs SARS-CoV Infection
    MPD2 is a Cereblon-binding ligand-based PROTAC that degrades MPro, the main protease of SARS-CoV-2. MPD2 effectively reduced MPro protein levels in 293T cells in a time-dependent manner (DC50=296 nM). MPD2 exhibited potent antiviral activity against multiple SARS-CoV-2 strains and had enhanced potency against Nirmatrelvir (HY-138687) resistant strains. MPD2 provides a new direction for antiviral drug development against SARS-CoV-2 and other emerging coronavirus pathogens (Sturcture Note:(Blue: Cereblon ligand (HY-14658), Black: linker (HY-W275882)；Red: SARS-CoV-2 MPro Inhibitor MP18 (HY-158763)) .
    MPD2

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: