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Results for "

NS-1

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

9

Natural
Products

13

Recombinant Proteins

3

Antibodies

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-134922
    NS1-IN-1

    		Influenza Virus Infection
    NS1-IN-1 (compound 3) is a potent NS1 inhibitor. NS1 is a major influenza A virus virulence factor that inhibits host gene expression. NS1-IN-1 decreases viral protein levels, contributing to the reduction of virus replication. NS1-IN-1 shows antiviral activity by repressing the activity of mTORC1 in a TSC1-TSC2-dependent manner [1].
    NS1-IN-1
  • HY-N11989
    Nanangenine B

    		Others Cancer
    Nanangenine B is a sesquiterpenoid, which can be isolated from Aspergillus nanangensis. Nanangenine B exhibits cytotixicity in cancer cell NS-1 with an IC50 of 38 μg/mL [1].
    Nanangenine B
  • HY-172745
    Conglobatin B1

    		Others Cancer
    Conglobatin B1 is a compound that can be isolated from Australian Streptomyces MST-91080. Conglobatin B1 is cytotoxic to the NS-1 myeloma cell line with an IC50 of 0.084 μg/mL, but has low toxicity to NFF human fibroblasts. Conglobatin B1 can be used in the study of cancer [1].
    Conglobatin B1
  • HY-N12264
    Burnettramic acid A

    		Antibiotic Bacterial Fungal Infection
    Burnettramic acid A is an antibiotic, which can be isolated from Aspergillus burnettii. Burnettramic acid A exhibits antibacterial and antifungal activities, with IC50 of 0.2, 0.5, 2.3 and 5.9 μg/mL, for Saccharomyces cerevisiae, Candida albicans, Bacillus subtilis and Staphylococcus aureus, respectively. Burnettramic acid A exhibits cytotoxicity in cancer cell NS-1 with IC50 of 13.8 μg/mL [1].
    Burnettramic acid A
  • HY-N15478
    Nanangenine G

    		Others Others
    Nanangenine G is a drimane sesquiterpene that has been found in Aspergillus. It is cytotoxic to NS-1 mouse myeloma cells (IC50 = 47 μg/ml).
    Nanangenine G
  • HY-158925
    Conglobatin C1

    		Endogenous Metabolite Cancer
    Conglobatin C1 is a bacterial metabolite and has anticancer activity. Conglobatin C1 is cytotoxic to NS-1 mouse myeloma cells (IC50 = 1.05 μg/mL) .
    Conglobatin C1
  • HY-N15480
    Nanangenine C

    		Bacterial Cancer
    Nanangenine C is a drimane sesquiterpene that has been found in Aspergillus. It is active against B. subtilis (IC50 = 5.7 μg/ml) and cytotoxic to NS-1 mouse myeloma cells (IC50 = 4.1 μg/ml).
    Nanangenine C
  • HY-118427
    Asterriquinol D dimethyl ether

    		Parasite Endogenous Metabolite Infection Cancer
    Asterriquinol D dimethyl ether is a fungal metabolite, which can inhibit mouse myeloma NS-1 cell lines with an IC50 of 28 μg/mL. Asterriquinol D dimethyl ether also inhibits Tritrichomonas foetus [1].
    Asterriquinol D dimethyl ether
  • HY-125092
    Drimentine C

    		Antibiotic Infection
    Drimentine C is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria. It inhibits proliferation of NS-1 murine β lymphocyte myeloma cells by 63 and 98% in vitro when used at concentrations of 12.5 and 100 μg/mL, respectively.
    Drimentine C
  • HY-118079
    Drimentine B

    		Endogenous Metabolite Infection
    Drimentine B is a terpenylated diketopiperazine originally isolated from Actinomycete bacteria that has anticancer activity. It inhibits the proliferation of NS-1 murine β lymphocyte myeloma cells by 41 and 59% in vitro when used at concentrations of 50 and 100 μg/mL, respectively.
    Drimentine B
  • HY-N10259
    Norfunalenone

    		Bacterial Infection Cancer
    Norfunalenone exhibits weak cytotoxic activity in mouse myeloma NS-1 cell line (ATCC TIB-18) with an IC50 of 70 μM. Norfunalenone also exhibits weak antibacterial activity against B. subtilis (MIC=100 μg/mL; IC50=265 μM) [1].
    Norfunalenone
  • HY-126136
    ML303

    		Influenza Virus Infection
    ML303 is a pyrazolopyridine influenza virus nonstructural protein 1 (NS1) antagonist (IC90 = 155 nM), with an EC50 of 0.7 μM for Influenza A virus H1N1 [1].
    ML303
  • HY-N15479
    Nanangenine F

    		Bacterial Infection Cancer
    Nanangenine F is a drimane sesquiterpenoid with weak antibacterial and anticancer activities. Nanangenine F inhibits Bacillus subtilis (ATCC 6633) with an IC50 of 78 µg/mL. Nanangenine F inhibits NS-1, DU-145, MCF-7 and human fibroblast NFF cells with IC50s of 49 µg/mL, 95 µg/mL, 49 µg/mL, and 84 µg/mL, respectively [1].
    Nanangenine F
  • HY-156004
    Ziapin 2

    		Bacterial Others
    Ziapin 2 is a molecular optomechanical light transducer. Ziapin 2 is an amphiphilic azobenzene with a strong non-covalent affinity to the plasma membrane. Ziapin 2 can be used to photo-modulate the membrane potential in cells of the Gram-positive bacterium Bacillus subtilis. Ziapin 2 enters the lipid membrane very rapidly (≈ 40 ns) .
    Ziapin 2
  • HY-RS07001
    IVNS1ABP Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    IVNS1ABP Human Pre-designed siRNA Set A contains three designed siRNAs for IVNS1ABP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    IVNS1ABP Human Pre-designed siRNA Set A
    IVNS1ABP Human Pre-designed siRNA Set A
  • HY-RS11416
    PTPN11 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    PTPN11 Human Pre-designed siRNA Set A contains three designed siRNAs for PTPN11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PTPN11 Human Pre-designed siRNA Set A
    PTPN11 Human Pre-designed siRNA Set A

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