NIRF

By Targets:	Amyloid-β (1) Complement System (1) Fluorescent Dye (2) Integrin (1) PSMA (1) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cancer (4) Neurological Disease (1)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (2) siRNAs (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D1565

Cy7.5 maleimide 1 Publications Verification	Fluorescent Dye	Others
Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .

HY-D1684

DCDAPH	Amyloid-β	Neurological Disease
DCDAPH (Compound 2c) is a novel smart NIRF probe for detection of β-amyloid (Aβ) plaques (λ_ex/λ_em=597/665 nm in PBS). DCDAPH shows high affinity for Aβ aggregates (K_i=37 nM, K_d=27 nM). DCDAPH shows good blood brain barrier permeation and can meet most of the requirements for the detection of Aβ plaques both in vitro and in vivo .

HY-P991650

MDX1201	PSMA	Cancer
MDX1201 is a humanized monoclonal antibody targeting PSMA1/7. MDX1201 conjugated with a fluorescent dye AlexaTM488 can be used as a probe for near-infrared fluorescence imaging (NIRF) imaging of prostate cancer .

HY-P11339

c-RGD-SH	Integrin	Cancer
c-RGD-SH is an Integrin αvβ3 ligand. c-RGD-SH conjugated with core-crosslinked polymeric micelles (CCPM) can be used for synthesis a dual modality nanoparticle probe, and this probe labeled with both Cy7 and ¹¹¹In can be used for SPECT and NIRF imaging of tumor .

HY-150979

Gd-NMC-3	Fluorescent Dye	Cancer
Gd-NMC-3 is a near-infrared fluorescence/magnetic resonance (NIRF/MR) bimodal imaging probe. Gd-NMC-3 shows high resolution and sensitivity in tumor imaging with good biocompatibility, indicating huge application potential .

HY-RS21074

Uhrf2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Uhrf2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Uhrf2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Uhrf2 Mouse Pre-designed siRNA Set A Uhrf2 Mouse Pre-designed siRNA Set A

HY-P10788

CK3 peptide	Complement System	Cancer
CK3 peptide is an NRP-1 targeting peptide with the amino acid sequence CLKADKAKC. The CK3 peptide specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging show significant accumulation of CK3 peptide in xenograft tumors in nude mice. CK3 peptide can be used for molecular imaging studies of breast cancer.

HY-RS06698

IL17B Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL17B Human Pre-designed siRNA Set A contains three designed siRNAs for IL17B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL17B Human Pre-designed siRNA Set A IL17B Human Pre-designed siRNA Set A

HY-RS15446

UHRF2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
UHRF2 Human Pre-designed siRNA Set A contains three designed siRNAs for UHRF2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

UHRF2 Human Pre-designed siRNA Set A UHRF2 Human Pre-designed siRNA Set A

Cat. No.	Product Name	Type

HY-D1565

Cy7.5 maleimide 1 Publications Verification	Fluorescent Dyes/Probes
Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .

Cy7.5 maleimide

1 Publications Verification

Fluorescent Dyes/Probes

Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .

HY-D1684

DCDAPH	Fluorescent Dyes/Probes
DCDAPH (Compound 2c) is a novel smart NIRF probe for detection of β-amyloid (Aβ) plaques (λ_ex/λ_em=597/665 nm in PBS). DCDAPH shows high affinity for Aβ aggregates (K_i=37 nM, K_d=27 nM). DCDAPH shows good blood brain barrier permeation and can meet most of the requirements for the detection of Aβ plaques both in vitro and in vivo .

HY-150979

Gd-NMC-3	Fluorescent Dyes/Probes
Gd-NMC-3 is a near-infrared fluorescence/magnetic resonance (NIRF/MR) bimodal imaging probe. Gd-NMC-3 shows high resolution and sensitivity in tumor imaging with good biocompatibility, indicating huge application potential .

Cat. No.	Product Name	Target	Research Area

HY-P11339

c-RGD-SH	Integrin	Cancer
c-RGD-SH is an Integrin αvβ3 ligand. c-RGD-SH conjugated with core-crosslinked polymeric micelles (CCPM) can be used for synthesis a dual modality nanoparticle probe, and this probe labeled with both Cy7 and ¹¹¹In can be used for SPECT and NIRF imaging of tumor .

HY-P10788

CK3 peptide	Complement System	Cancer
CK3 peptide is an NRP-1 targeting peptide with the amino acid sequence CLKADKAKC. The CK3 peptide specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging show significant accumulation of CK3 peptide in xenograft tumors in nude mice. CK3 peptide can be used for molecular imaging studies of breast cancer.

Cat. No.	Product Name	Target	Research Area

HY-P991650

MDX1201	PSMA	Cancer
MDX1201 is a humanized monoclonal antibody targeting PSMA1/7. MDX1201 conjugated with a fluorescent dye AlexaTM488 can be used as a probe for near-infrared fluorescence imaging (NIRF) imaging of prostate cancer .

Species:	Human (4) Mouse (4)
Tag:	His (3) Tag Free (1) Avi (2) Fc (4)
Source:	HEK293 (3) Sf9 insect cells (1) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source

HY-P72588

	IL-17B Protein, Human (HEK293, Fc) Interleukin-17B; IL-17B; Cytokine Zcyto7; IL-20; NIRF; ZCYTO7	Human	HEK293
	IL-17B is a proinflammatory cytokine and stimulates the release of tumour necrosis factor alpha (TNFα) and IL-1β. IL-17B plays an important role in cancer progression, angiogenesis, and inflammatory arthritis. IL-17B Protein, Human (HEK293, Fc) is a recombinant human IL-17B protein with hFc tag at the C-terminus and is expressed in HEK293 cells.

HY-P75835

	IL-17B Protein, Mouse (sf9, Fc) Interleukin-17B; IL-17B; Cytokine Zcyto7; IL-20; NIRF; ZCYTO7	Mouse	Sf9 insect cells
	IL-17B is a proinflammatory cytokine and stimulates the release of tumour necrosis factor alpha (TNFα) and IL-1β. IL-17B plays an important role in cancer progression, angiogenesis, and inflammatory arthritis. IL-17B Protein, Mouse (sf9, Fc) is a recombinant mouse IL-17B protein with hFc tag at the C-terminus and is expressed in Sf9 insect cells. It consists of 180 amino acids (M1-F180).

HY-P700105AF

	Animal-Free IL-17B Protein, Human (His) Interleukin-17B; IL-17B; Cytokine Zcyto7; IL-20; NIRF; ZCYTO7	Human	E. coli
	IL-17B Proteinas, crucial in cellular signaling, induces the release of pro-inflammatory cytokines, TNF-α, and IL-1β from THP-1 monocytic cells.Its role in regulating immune responses and inflammatory processes underscores its potential significance in mediating crosstalk between immune cells, contributing to overall immune homeostasis.Animal-Free IL-17B Protein, Human (His) is the recombinant human-derived animal-FreeIL-17B protein, expressed by E.coli , with C-His labeled tag.This product is for cell culture use only.

HY-P78315

	IL-17B Protein, Mouse (His) 1 Publications Verification IL-17B; Cytokine CX1; IL20; interleukin 17B; interleukin 20; MGC138900; MGC138901; NIRF; ZCYTO7	Mouse	E. coli
	IL-17B is a proinflammatory cytokine and stimulates the release of tumour necrosis factor alpha (TNFα) and IL-1β. IL-17B plays an important role in cancer progression, angiogenesis, and inflammatory arthritis. IL-17B Protein, Mouse (His) is a recombinant mouse IL-17B protein with His tag at the N-terminus and is expressed in E. coli. It consists of 160 amino acids (H21-F180).

HY-P78315AF

	Animal-Free IL-17B Protein, Mouse (His) IL-17B; Cytokine CX1; IL20; interleukin 17B; interleukin 20; MGC138900; MGC138901; NIRF; ZCYTO7	Mouse	E. coli
	IL-17B Proteinas, a key immune response regulator, stimulates THP-1 monocytic cells to release pro-inflammatory cytokines, TNF-α, and IL-1β. Its crucial role in orchestrating immune reactions and inflammatory pathways positions it as a potential modulator of immune homeostasis, making it a therapeutic intervention target for regulating inflammatory processes. Animal-Free IL-17B Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-17B protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

HY-P71856

	IL-17B Protein, Human Cytokine like protein Zcyto7; Cytokine Zcyto7; IL 20 ; IL-17B; IL17B_HUMAN; IL20 ; Interleukin 17 beta; Interleukin 17B; Interleukin-17B; Interleukin-20; MGC138900; MGC138901; Neuronal interleukin 17 related factor ; Neuronal interleukin-17-related factor; NIRF; ZCYTO7	Human	E. coli
	IL-17B Proteinas, crucial in cellular signaling, induces the release of pro-inflammatory cytokines, TNF-α, and IL-1β from THP-1 monocytic cells. Its role in regulating immune responses and inflammatory processes underscores its potential significance in mediating crosstalk between immune cells, contributing to overall immune homeostasis. IL-17B Protein, Human is the recombinant human-derived IL-17B protein, expressed by E. coli , with tag free.

HY-P705152

	IL-17B Protein, Human (Biotinylated, HEK293, Fc-Avi) Interleukin-17B; IL-17B; Cytokine Zcyto7; IL-20; NIRF; ZCYTO7	Human	HEK293

HY-P705257

	IL-17B Protein, Mouse (Biotinylated, HEK293, Fc-Avi) Interleukin-17B; IL-17B; Cytokine Zcyto7; IL-20; NIRF; ZCYTO7	Mouse	HEK293

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Cat. No.	Product Name		Classification

HY-RS21074

Uhrf2 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Uhrf2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Uhrf2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS06698

IL17B Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
IL17B Human Pre-designed siRNA Set A contains three designed siRNAs for IL17B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS15446

UHRF2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
UHRF2 Human Pre-designed siRNA Set A contains three designed siRNAs for UHRF2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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