2. Search Result
Search Result
Results for "

NDRG1

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

1

Recombinant Proteins

3

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145723
    MAX-40279
    1 Publications Verification

    		 FLT3 FGFR Inflammation/Immunology Cancer
    MAX-40279 is a dual and orally active inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 is also effective against the FLT3 mutants such as FLT3 D835Y, suggesting that it can overcome resistance to Quizartinib (HY-13001) and Sorafenib (HY-10201). MAX-40279 inhibits NDRG1 phosphorylation at Ser330 and suppresses endothelial-to-mesenchymal transition (EndMT). MAX-40279 can be used for the research of acute myelogenous leukemia (AML) [1] .
    MAX-40279
  • HY-145723B
    MAX-40279 hemifumarate
    1 Publications Verification

    		 FLT3 FGFR Inflammation/Immunology Cancer
    MAX-40279 hemifumarate is a dual and orally active inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hemifumarate is also effective against the FLT3 mutants such as FLT3 D835Y, suggesting that it can overcome resistance to Quizartinib (HY-13001) and Sorafenib (HY-10201). MAX-40279 hemifumarate inhibits NDRG1 phosphorylation at Ser330 and suppresses endothelial-to-mesenchymal transition (EndMT). MAX-40279 hemifumarate can be used for the research of acute myelogenous leukemia (AML) [1] .
    MAX-40279 hemifumarate
  • HY-145723C
    MAX-40279 hemiadipate
    1 Publications Verification

    		 FLT3 FGFR Inflammation/Immunology Cancer
    MAX-40279 hemiadipate is a dual and orally active inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hemiadipate is also effective against the FLT3 mutants such as FLT3 D835Y, suggesting that it can overcome resistance to Quizartinib (HY-13001) and Sorafenib (HY-10201). MAX-40279 hemiadipate inhibits NDRG1 phosphorylation at Ser330 and suppresses endothelial-to-mesenchymal transition (EndMT). MAX-40279 hemiadipate can be used for the research of acute myelogenous leukemia (AML) [1] .
    MAX-40279 hemiadipate
  • HY-125878
    PROTAC SGK3 degrader-1
    4 Publications Verification

    SGK3-PROTAC1

    		 PROTACs SGK Cancer
    PROTAC SGK3 degrader-1 (SGK3-PROTAC1), a chemical probe, is a von Hippel-Lindau ligand-based SKG3 PROTAC composed of a PEG3-C4-OBn (HY-130620) alkyl linker, an SGK3 degrader (red structure), and a VHL ligand (HY-150803, blue structure). PROTAC SGK3 degrader-1 (0.3 μM) induced 50% endogenous SGK3 degradation within 2 hours, and 80% SGK3 degradation was observed at 8 hours, accompanied by loss of phosphorylation of NDRG1 (SGK3 substrate) [1].
    PROTAC SGK3 degrader-1
  • HY-RS17382
    Ndrg1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Ndrg1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ndrg1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ndrg1 Mouse Pre-designed siRNA Set A
    Ndrg1 Mouse Pre-designed siRNA Set A
  • HY-RS09114
    NDRG1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    NDRG1 Human Pre-designed siRNA Set A contains three designed siRNAs for NDRG1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    NDRG1 Human Pre-designed siRNA Set A
    NDRG1 Human Pre-designed siRNA Set A
  • HY-RS23837
    Ndrg1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Ndrg1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ndrg1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ndrg1 Rat Pre-designed siRNA Set A
    Ndrg1 Rat Pre-designed siRNA Set A
  • HY-145723A
    MAX-40279 hydrochloride

    		FLT3 FGFR Inflammation/Immunology Cancer
    MAX-40279 hydrochloride is a dual and orally active inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hydrochloride is also effective against the FLT3 mutants such as FLT3 D835Y, suggesting that it can overcome resistance to Quizartinib (HY-13001) and Sorafenib (HY-10201). MAX-40279 hydrochloride inhibits NDRG1 phosphorylation at Ser330 and suppresses endothelial-to-mesenchymal transition (EndMT). MAX-40279 hydrochloride can be used for the research of acute myelogenous leukemia (AML) [1] .
    MAX-40279 hydrochloride

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: