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Micronuclei

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (1) Adrenergic Receptor (1) Akt (1) Apoptosis (1) Bacterial (1) Cytochrome P450 (1) DNA/RNA Synthesis (2) Fluorescent Dye (1) Fungal (1) Interleukin Related (1) Isotope-Labeled Compounds (2) PI3K (1) TNF Receptor (1) Topoisomerase (1)
By Research Areas:	Cancer (4) Endocrinology (1) Infection (2) Inflammation/Immunology (1)

Inhibitors & Agonists

Fluorescent Dye

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W683760

N-Nitrosonornicotine (2S)-N'-Nitrosonornicotine	DNA/RNA Synthesis	Cancer
N-Nitrosonornicotine is a tobacco-specific nitrosamine that has carcinogenic and mutagenic activity, and it can induce micronuclei in C3A cells. N-Nitrosonornicotine can form DNA adducts .

HY-119983

7H-Dibenzo[c,g]carbazole DBC	Cytochrome P450	Cancer
7H-Dibenzo[c,g]carbazole (DBC) is an azaarene with high lipophilicity. 7H-Dibenzo[c,g]carbazole has carcinogenic activity and induce DNA adducts in fish, DNA adducts, mutations in diploid human fibroblasts and micronuclei in human blood lymphocytes. 7H-Dibenzo[c,g]carbazole is activated by cytochrome P450 enzymes resulting mainly in the generation of phenolic metabolites .

HY-N6739

Beauvericin	Bacterial Apoptosis Fungal PI3K Akt TNF Receptor Interleukin Related	Infection Cancer
Beauvericin is a cyclohexapeptide Fusarium toxin with insecticidal, antibacterial, anticancer, antiviral and cytotoxic activities. Beauvericin causes cellular genotoxicity by producing DNA breaks, chromosomal aberrations and micronuclei, and inhibits the PI3K/AKT pathway to induce apoptosis, thereby inhibiting the growth of HCC. In addition, Beauvericin affects immune function by inhibiting lymphocyte proliferation and interfering with the differentiation process of human monocytes into macrophages .

HY-W271064

1-Methylpyrene	Fluorescent Dye	Others
1-Methylpyrene is a ubiquitous environmental pollutant and rodent carcinogen. Its mutagenic activity depends on sequential activation by various CYP and sulfotransferase (SULT) enzymes. 1-Methylpyrene induces chromosome loss and mitotic disturbance, proba

HY-118379

NU/ICRF 500	Topoisomerase	Inflammation/Immunology
NU/ICRF 500 is a topo II catalytic inhibitor which increases CREST negative micronuclei in human lymphocytes .

HY-W726392

N-Nitrosometoprolol	Adrenergic Receptor	Endocrinology
N-Nitrosometoprolol is an N-nitroso derivative formed by the in vitro reaction of β-adrenergic blockers with sodium nitrite. N-Nitrosometoprolol can induce micronuclei in rat liver, bone marrow and spleen .

HY-W743781

N-Nitrosonornicotine-d4 (2S)-N'-Nitrosonornicotine-d₄	Isotope-Labeled Compounds DNA/RNA Synthesis	Cancer
N-Nitrosonornicotine-d₄ ((2S)-N'-Nitrosonornicotine-d₄) is deuterium labeled N-Nitrosonornicotine. N-Nitrosonornicotine is a tobacco-specific nitrosamine that has carcinogenic and mutagenic activity, and it can induce micronuclei in C3A cells. N-Nitrosonornicotine can form DNA adducts .

HY-N6739S

Beauvericin-13C45	Acyltransferase Isotope-Labeled Compounds	Infection
Beauvericin- ¹³C₄₅ is ¹³C labeled Beauvericin (HY-N6739). Beauvericin is a cyclohexapeptide Fusarium toxin with insecticidal, antibacterial, anticancer, antiviral and cytotoxic activities. Beauvericin causes cellular genotoxicity by producing DNA breaks, chromosomal aberrations and micronuclei, and inhibits the PI3K/AKT pathway to induce apoptosis, thereby inhibiting the growth of HCC. In addition, Beauvericin affects immune function by inhibiting lymphocyte proliferation and interfering with the differentiation process of human monocytes into macrophages .

Cat. No.	Product Name	Type

HY-W271064

1-Methylpyrene	Fluorescent Dyes/Probes
1-Methylpyrene is a ubiquitous environmental pollutant and rodent carcinogen. Its mutagenic activity depends on sequential activation by various CYP and sulfotransferase (SULT) enzymes. 1-Methylpyrene induces chromosome loss and mitotic disturbance, proba

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6739

Beauvericin	Cardiovascular Disease Structural Classification Human Gut Microbiota Metabolites Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Endogenous metabolite Disease Research Fields	Bacterial Apoptosis Fungal PI3K Akt TNF Receptor Interleukin Related
Beauvericin is a cyclohexapeptide Fusarium toxin with insecticidal, antibacterial, anticancer, antiviral and cytotoxic activities. Beauvericin causes cellular genotoxicity by producing DNA breaks, chromosomal aberrations and micronuclei, and inhibits the PI3K/AKT pathway to induce apoptosis, thereby inhibiting the growth of HCC. In addition, Beauvericin affects immune function by inhibiting lymphocyte proliferation and interfering with the differentiation process of human monocytes into macrophages .

Cat. No.	Product Name	Chemical Structure

HY-W743781

N-Nitrosonornicotine-d4
N-Nitrosonornicotine-d₄ ((2S)-N'-Nitrosonornicotine-d₄) is deuterium labeled N-Nitrosonornicotine. N-Nitrosonornicotine is a tobacco-specific nitrosamine that has carcinogenic and mutagenic activity, and it can induce micronuclei in C3A cells. N-Nitrosonornicotine can form DNA adducts .

HY-N6739S

Beauvericin-13C45
Beauvericin- ¹³C₄₅ is ¹³C labeled Beauvericin (HY-N6739). Beauvericin is a cyclohexapeptide Fusarium toxin with insecticidal, antibacterial, anticancer, antiviral and cytotoxic activities. Beauvericin causes cellular genotoxicity by producing DNA breaks, chromosomal aberrations and micronuclei, and inhibits the PI3K/AKT pathway to induce apoptosis, thereby inhibiting the growth of HCC. In addition, Beauvericin affects immune function by inhibiting lymphocyte proliferation and interfering with the differentiation process of human monocytes into macrophages .

Beauvericin-13C45

Beauvericin- ¹³C₄₅ is ¹³C labeled Beauvericin (HY-N6739). Beauvericin is a cyclohexapeptide Fusarium toxin with insecticidal, antibacterial, anticancer, antiviral and cytotoxic activities. Beauvericin causes cellular genotoxicity by producing DNA breaks, chromosomal aberrations and micronuclei, and inhibits the PI3K/AKT pathway to induce apoptosis, thereby inhibiting the growth of HCC. In addition, Beauvericin affects immune function by inhibiting lymphocyte proliferation and interfering with the differentiation process of human monocytes into macrophages .

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