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Mesaconine 14-benzoate

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0218
    Benzoylmesaconine
    1 Publications Verification

    Mesaconine 14-benzoate

    		 NF-κB Interleukin Related Inflammation/Immunology
    Benzoylmesaconine is a monoester-type alkaloid and is the most abundant component of Wutou decoction, which is widely used in China for rheumatoid arthritis. Benzoylmesaconine exhibits potent anti-inflammatory properties by inhibiting NF-κB. Benzoylmesaconine can suppress NLRP3 inflammasome activation by inhibiting IL-1β secretion and GSDMD-N protein expression. Benzoylmesaconine reduces intracellular K + efflux and disrupts NLRP3 inflammasome assembly .
    Benzoylmesaconine

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