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Manganese

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Apoptosis (1) Arginase (1) Bacterial (6) Biochemical Assay Reagents (14) Calcium Channel (2) Cytochrome P450 (2) Endogenous Metabolite (3) ERK (1) Fluorescent Dye (2) Fungal (4) GPR84 (1) HDAC (1) Heme Oxygenase (HO) (1) Histone Acetyltransferase (1) Isotope-Labeled Compounds (1) Reactive Oxygen Species (ROS) (4) Reference Standards (4) SOD (1)
By Research Areas:	Cancer (5) Cardiovascular Disease (1) Endocrinology (1) Infection (7) Inflammation/Immunology (2) Metabolic Disease (3) Neurological Disease (3)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W094492

Manganese acetate tetrahydrate Manganese(Ii) acetate tetrahydrate	Biochemical Assay Reagents	Others
Manganese acetate tetrahydrate (Manganese(Ii) acetate tetrahydrate) is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W019894

Manganese chloride Manganese dichloride	Biochemical Assay Reagents	Others
Manganese chloride is a new oral active magnetic resonance liver contrast agent for patients with renal impairment .

HY-W001583

Manganese(salen) chloride 1 Publications Verification EUK-8	Reactive Oxygen Species (ROS)	Cardiovascular Disease
Manganese(salen) chloride (EUK-8), a superoxide dismutase and catalase mimetic, is an antioxidant with oxyradical scavenging properties. Manganese(salen) chloride ameliorates acute lung injury in endotoxemic swine .

HY-W134021

Manganese dihydrogen phosphate	Biochemical Assay Reagents	Others
Manganese dihydrogen phosphate is a kind of biological materials or organic compounds that are widely used in life science research .

HY-Y1369C

Manganese sulfate monohydrate, for cell culture Manganous sulfate monohydrate, for cell culture	Biochemical Assay Reagents	Others
Manganese sulfate monohydrate, for cell culture (Manganous sulfate monohydrate, for cell culture) can be used to prepare micronutrients. Manganese sulfate monohydrate, for cell culture is a biomaterial or organic compound that can be used as a life science research-related material .

HY-109521A

Manganese chloride (tetrahydrate), molecular biology grade,≥99.0% (KT) Manganese(Ⅱ) chloride (tetrahydrate), molecular biology grade,≥99.0% (KT)	Biochemical Assay Reagents Histone Acetyltransferase HDAC	Neurological Disease
Manganese chloride (tetrahydrate), molecular biology grade,≥99.0% (KT) is an orally active and a blood-brain barrier penetrant compound. It affects the activities of multiple enzymes in cells, such as regulating the activities of histone acetyltransferase (HAT) and histone deacetylase (HDAC), thereby affecting gene expression. It has multiple activities such as neurotoxicity, embryotoxicity, and reproductive toxicity. It is currently mainly used in neurodegenerative diseases and toxicology research.

HY-137356

Prochloraz manganese	Fungal	Infection
Prochloraz manganese is an antifungal agent, and is used in agricultural industries .

HY-132188

Manganese peroxidase	Endogenous Metabolite	Others
Manganese peroxidase is a heme protein that oxidizes Mn2+ to Mn3+. Manganese peroxidase catalyzes plant lignin de-polymerization. Manganese peroxidase can be used for the biodegradation of hazardous environmental contaminants, and especially for dye wastewater decolorization .

HY-W854721

Mn(III) Protoporphyrin IX chloride Manganese(III) Protoporphyrin IX Chloride	Heme Oxygenase (HO)	Metabolic Disease
Mn(III) protoporphyrin IX chloride is a metalloporphyrin. It induces mRNA expression of the genes encoding δ-aminolevulinate synthase and heme oxygenase (HO), enzymes that catalyze the rate-limiting steps of heme biosynthesis and degradation, respectively, in chick embryo liver cells when used at a concentration of 10 μM. Mn(III) protoporphyrin IX chloride-containing nanobialys have been used in magnetic resonance imaging (MRI) of fibrin clots in vitro. It has also been used in the synthesis of Mn(III) protoporphyrin IX-6(7)-glycyl-glycyl-L-histidine methyl ester (MnGGH), a metalloporphyrin conjugate with microperoxidase activity.

HY-137356R

*Prochloraz manganese* (Standard)**	Fungal Reference Standards	Infection
Prochloraz manganese (Standard) is the analytical standard of Prochloraz manganese. This product is intended for research and analytical applications. Prochloraz manganese is an antifungal agent, and is used in agricultural industries .

HY-132829

Rucosopasem manganese GC4711	Reactive Oxygen Species (ROS)	Cancer
Rucosopasem manganese (GC4711) is a selective superoxide dismutase mimetic that converts superoxide to hydrogen peroxide. Rucosopasem manganese can be used for the research of cancer .

HY-13336

Imisopasem manganese 2 Publications Verification M40403; GC4403	SOD	Cancer
Imisopasem manganese (M40403) is a stable non-peptidyl mimetic of manganese superoxide MnSOD.

HY-W115799

EDTA disodium manganese Ethylenediaminetetraacetic acid disodium Manganese	Biochemical Assay Reagents	Others
Disodium manganese EDTA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-109110

Avasopasem manganese GC-4419; M-40419	Reactive Oxygen Species (ROS)	Inflammation/Immunology Cancer
Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O₂ ^- to hydrogen peroxide (H₂O₂), arresting the initiation of this cascade. Avasopasem manganese* can be used for the research of severe oral mucositis (SOM) and cancer .

HY-W103826

*(5,10,15,20-Tetraphenylporphinato)manganese(III) chloride* 5,10,15,20-Tetraphenyl-21H,23H-porphine Manganese(III) chloride	Biochemical Assay Reagents	Others
(5,10,15,20-Tetraphenylporphinato)manganese(III) chloride (5,10,15,20-Tetraphenyl-21H,23H-porphine Manganese(III) chloride) is an organic compound with catalytic capabilities .

HY-W441531

*2,3,7,8,12,13,17,18-Octaethyl-21H,23H-porphine manganese(III) chloride*	Biochemical Assay Reagents
2,3,7,8,12,13,17,18-Octaethyl-21H,23H-porphine manganese(III) chloride is a transition metal compound with excellent catalytic activity. 2,3,7,8,12,13,17,18-Octaethyl-21H,23H-porphine manganese(III) chloride is widely used in photocatalytic reactions to improve reaction efficiency. 2,3,7,8,12,13,17,18-Octaethyl-21H,23H-porphine manganese(III) chloride is also used in the preparation of optical materials, giving the materials excellent light absorption properties. The biological activity of 2,3,7,8,12,13,17,18-Octaethyl-21H,23H-porphine manganese(III) chloride has gradually attracted attention in the research of the medical field.

HY-130574

MnTE-2-PyP chloride BMX-010 chloride	Reactive Oxygen Species (ROS)	Cancer
MnTE-2-PyP (BMX-010) chloride is a ROS scavenger and potent radioprotector. MnTE-2-PyP also is a manganese porphyrin, protects normal prostate tissue from radiation damage. MnTE-2-PyP can be used for the research of diabetic prostate cancer .

HY-12764R

6-OAU (Standard) GTPL5846 (Standard)	Reference Standards GPR84 ERK Bacterial Antibiotic	Inflammation/Immunology
Prochloraz manganese (Standard) is the analytical standard of Prochloraz manganese. This product is intended for research and analytical applications. Prochloraz manganese is an antifungal agent, and is used in agricultural industries .

HY-W102714

1,2-Cyclohexylenedinitrilotetraacetic acid CDTA	Biochemical Assay Reagents	Neurological Disease
1,2-Cyclohexylenedinitrilotetraacetic acid (CDTA) is a chelating agent. 1,2-Cyclohexylenedinitrilotetraacetic acid has an ability to remove manganese from brain and liver (in vivo) and their sub-cellular fractions (in vitro), of rats pretreated with manganese sulphate .

HY-N11583

Jasmololone Jasmololon	Others	Others
Jasmololone (compound 1c) is a reduced compound that can be oxidized by manganese dioxide to form the corresponding diketone .

HY-D1229

Pigment Red 48:4	Fluorescent Dye	Others
Pigment Red 48:4 is a manganese-complex dye that can be used in printing ink applications and paint systems.

HY-W102714R

1,2-Cyclohexylenedinitrilotetraacetic acid (Standard) CDTA (Standard)	Biochemical Assay Reagents Reference Standards	Neurological Disease
1,2-Cyclohexylenedinitrilotetraacetic acid (Standard) is the analytical standard of 1,2-Cyclohexylenedinitrilotetraacetic acid (HY-W102714). This product is intended for research and analytical applications. 1,2-Cyclohexylenedinitrilotetraacetic acid (CDTA) is a chelating agent. 1,2-Cyclohexylenedinitrilotetraacetic acid has an ability to remove manganese from brain and liver (in vivo) and their sub-cellular fractions (in vitro), of rats pretreated with manganese sulphate .

HY-115853

Pyclen	Biochemical Assay Reagents	Others
Pyclen is a compound used for liver-specific MRI. Related compounds were synthesized as ligands of manganese (II) and have certain relaxivity and hepatocyte uptake ability. It is a potential liver-specific contrast agent.

HY-115853A

Pyclen dihydrochloride	Biochemical Assay Reagents	Others
Pyclen dihydrochloride is a compound used for liver-specific MRI. Related compounds are synthesized as ligands of manganese (II) and have certain relaxivity and hepatocyte uptake ability. Pyclen dihydrochloride is a potential liver-specific contrast agent .

HY-W787537

Leucoberbelin blue I LBB	Biochemical Assay Reagents	Others
Leucoberbelin blue I (LBB) is a leuco base that is oxidized by manganese through a hydrogen atom transfer reaction forming a colored complex. Leucoberbelin blue I can be used to quantify or confirm the Mn (II) oxides formation .

HY-19548

BEC	Arginase	Endocrinology
BEC, an arginine analogue, is a slow-binding competitive inhibitor of the *binuclear manganese* metalloenzyme arginase**. BEC enhances substrate flux to NO synthase, thereby enhancing NO-dependent smooth muscle relaxation in the corpus cavernosum, and enhances penile erection .

HY-157359

Bacterial Organophosphorus Medium	Biochemical Assay Reagents	Others
Bacterial Organophosphorus Medium can be used to determine the efficiency of phosphorus bacteria in decomposing organic phosphorus in phosphorus bacteria fertilizers. Bacterial Organophosphorus Medium ingredients include glucose, ammonium sulfate, yeast extract, sodium chloride, potassium chloride, magnesium sulfate, ferrous sulfate, manganese sulfate, lecithin, calcium carbonate, agar .

HY-B0885

Econazole 3 Publications Verification (±)-Econazol	Fungal Bacterial Calcium Channel Cytochrome P450	Infection Metabolic Disease
Econazole ((±)-Econazol) is an orally active imidazole antifungal agent, as well as a cytochrome P-450 inhibitor and a blocker of calcium and manganese ion uptake. Econazole is active against a variety of fungi and some Gram-positive bacteria, but has no significant activity against Gram-negative bacteria. Econazole can inhibit the synthesis of prostaglandins and can also induce liver damage .

HY-107858

Veratryl alcohol 3,4-Dimethoxybenzyl alcohol	Endogenous Metabolite Bacterial	Infection
Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H₂O₂ and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy .

HY-B0885R

Econazole (Standard) (±)-Econazol (Standard)	Reference Standards Fungal Bacterial Calcium Channel Cytochrome P450	Infection Metabolic Disease
Econazole (Standard) ((±)-Econazol (Standard)) is the analytical standard of Econazole (HY-B0885). This product is intended for research and analytical applications. Econazole ((±)-Econazol) is an orally active imidazole antifungal agent, as well as a cytochrome P-450 inhibitor and a blocker of calcium and manganese ion uptake. Econazole is active against a variety of fungi and some Gram-positive bacteria, but has no significant activity against Gram-negative bacteria. Econazole can inhibit the synthesis of prostaglandins and can also induce liver damage .

HY-D0948

Celestine Blue	Fluorescent Dye	Infection
Celestine Blue is a electroactive indicator in DNA biosensors. Celestine Blue is strongly adsorbed on the spinel phases and CNT (carbon nanotubes), facilitates dispersion, acts as a capping agent and allows for the fabrication of spinel decorated CNT. Celestine Blue is an efficient charge transfer mediator, which allows for significant improvement of capacitive behavior. TiO₂ nanoparticles doped with Celestine Blue can be used as a label in a sandwich immunoassay for the hepatitis C virus (HCV) core antigen .

HY-W738271

Veratryl alcohol-13C 3,4-Dimethoxybenzyl alcohol-¹³C	Isotope-Labeled Compounds Bacterial Endogenous Metabolite	Infection
Veratryl alcohol- ¹³C (3,4-Dimethoxybenzyl alcohol- ¹³C) is the ¹³C-labeled Veratryl alcohol (HY-107858). Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H2O2 and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy .

HY-138185

Collismycin A SF 2738A	Bacterial Apoptosis	Cancer
Collismycin A is a bacterial metabolite originally isolated from Streptomyces that has diverse biological activities, including antibacterial, antiproliferative, and neuroprotective properties. It is active against a variety of bacteria (MICs=6.25 and 100 μg/mL) and fungi (MICs=12.5-100 μg/mL). It inhibits proliferation of A549 lung, HCT116 colon, and HeLa cervical cancer cells (IC₅₀s=0.3, 0.6, and 0.3 μM, respectively) and NIH373 fibroblasts (IC₅₀=56.6 μM) but not MDA-MD-231 breast cancer cells (IC₅₀=>100 μM). Collismycin A forms a complex with Fe(II) and Fe(III) at a 2:1 ratio, and the addition of iron ions inhibits the antiproliferative effect of collismycin A on HeLa cells, an effect that does not occur with the addition of zinc, manganese, copper, or magnesium ions.3 Collismycin A (1 μM) prevents apoptosis in the brain region of zebrafish larvae in a model of neuronal cell death induced by all-trans retinoic acid.

Cat. No.	Product Name	Type

HY-D0948

Celestine Blue	Dyes
Celestine Blue is a electroactive indicator in DNA biosensors. Celestine Blue is strongly adsorbed on the spinel phases and CNT (carbon nanotubes), facilitates dispersion, acts as a capping agent and allows for the fabrication of spinel decorated CNT. Celestine Blue is an efficient charge transfer mediator, which allows for significant improvement of capacitive behavior. TiO₂ nanoparticles doped with Celestine Blue can be used as a label in a sandwich immunoassay for the hepatitis C virus (HCV) core antigen .

Celestine Blue

Dyes

Celestine Blue is a electroactive indicator in DNA biosensors. Celestine Blue is strongly adsorbed on the spinel phases and CNT (carbon nanotubes), facilitates dispersion, acts as a capping agent and allows for the fabrication of spinel decorated CNT. Celestine Blue is an efficient charge transfer mediator, which allows for significant improvement of capacitive behavior. TiO₂ nanoparticles doped with Celestine Blue can be used as a label in a sandwich immunoassay for the hepatitis C virus (HCV) core antigen .

Cat. No.	Product Name	Type

HY-W094492

Manganese acetate tetrahydrate Manganese(Ii) acetate tetrahydrate	Biochemical Assay Reagents
Manganese acetate tetrahydrate (Manganese(Ii) acetate tetrahydrate) is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W134021

Manganese dihydrogen phosphate	Biochemical Assay Reagents
Manganese dihydrogen phosphate is a kind of biological materials or organic compounds that are widely used in life science research .

HY-Y1369C

Manganese sulfate monohydrate, for cell culture Manganous sulfate monohydrate, for cell culture	Cell Assay Reagents
Manganese sulfate monohydrate, for cell culture (Manganous sulfate monohydrate, for cell culture) can be used to prepare micronutrients. Manganese sulfate monohydrate, for cell culture is a biomaterial or organic compound that can be used as a life science research-related material .

HY-109521A

Manganese chloride (tetrahydrate), molecular biology grade,≥99.0% (KT) Manganese(Ⅱ) chloride (tetrahydrate), molecular biology grade,≥99.0% (KT)	Buffer Reagents
Manganese chloride (tetrahydrate), molecular biology grade,≥99.0% (KT) is an orally active and a blood-brain barrier penetrant compound. It affects the activities of multiple enzymes in cells, such as regulating the activities of histone acetyltransferase (HAT) and histone deacetylase (HDAC), thereby affecting gene expression. It has multiple activities such as neurotoxicity, embryotoxicity, and reproductive toxicity. It is currently mainly used in neurodegenerative diseases and toxicology research.

Manganese chloride (tetrahydrate), molecular biology grade,≥99.0% (KT)

Manganese(Ⅱ) chloride (tetrahydrate), molecular biology grade,≥99.0% (KT)

Buffer Reagents

Manganese chloride (tetrahydrate), molecular biology grade,≥99.0% (KT) is an orally active and a blood-brain barrier penetrant compound. It affects the activities of multiple enzymes in cells, such as regulating the activities of histone acetyltransferase (HAT) and histone deacetylase (HDAC), thereby affecting gene expression. It has multiple activities such as neurotoxicity, embryotoxicity, and reproductive toxicity. It is currently mainly used in neurodegenerative diseases and toxicology research.

HY-W115799

EDTA disodium manganese Ethylenediaminetetraacetic acid disodium Manganese	Chelators
Disodium manganese EDTA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W787537

Leucoberbelin blue I LBB	Indicators
Leucoberbelin blue I (LBB) is a leuco base that is oxidized by manganese through a hydrogen atom transfer reaction forming a colored complex. Leucoberbelin blue I can be used to quantify or confirm the Mn (II) oxides formation .

HY-157359

Bacterial Organophosphorus Medium	Microbial Culture
Bacterial Organophosphorus Medium can be used to determine the efficiency of phosphorus bacteria in decomposing organic phosphorus in phosphorus bacteria fertilizers. Bacterial Organophosphorus Medium ingredients include glucose, ammonium sulfate, yeast extract, sodium chloride, potassium chloride, magnesium sulfate, ferrous sulfate, manganese sulfate, lecithin, calcium carbonate, agar .

Cat. No.	Product Name	Target	Research Area

HY-P5230

Manganese tripeptide-1	Peptides	Others
Manganese tripeptide-1 is a bioactive peptide with anti-wrinkle and reducing skin hyperpigmentation effect, and has been reported used as a cosmetic ingredient .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-107858

Veratryl alcohol 3,4-Dimethoxybenzyl alcohol	Structural Classification Natural Products Microorganisms Classification of Application Fields Other Diseases Disease Research Fields	Endogenous Metabolite Bacterial
Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H₂O₂ and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy .

HY-132188

Manganese peroxidase	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Manganese peroxidase is a heme protein that oxidizes Mn2+ to Mn3+. Manganese peroxidase catalyzes plant lignin de-polymerization. Manganese peroxidase can be used for the biodegradation of hazardous environmental contaminants, and especially for dye wastewater decolorization .

HY-N11583

Jasmololone Jasmololon	Structural Classification Natural Products Source classification Plants Compositae Bidens parviflora Willd.	Others
Jasmololone (compound 1c) is a reduced compound that can be oxidized by manganese dioxide to form the corresponding diketone .

Species:	Human (2)
Tag:	His (2) Strep (1) MBP (1) Flag (2)
Source:	Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P702033

	SLC30A10 Protein, Human (sf9, His, MBP, FLAG) SLC30A10; Zinc transporter 10; ZnT-10; Manganese transporter SLC30A10; Solute carrier family 30 member 10	Human	Sf9 insect cells
	The SLC30A10 protein is a plasma membrane calcium:manganese antiporter that promotes the release of intracellular manganese and the simultaneous import of extracellular calcium. SLC30A10 Protein, Human (sf9, His, MBP, FLAG) is the recombinant human-derived SLC30A10 protein, expressed by sf9 insect cells , with N-MBP, C-Flag, N-8*His labeled tag.

HY-P702010

	SLC30A10 Protein, Human (sf9, His, StrepⅡ, FLAG) SLC30A10; Zinc transporter 10; ZnT-10; Manganese transporter SLC30A10; Solute carrier family 30 member 10	Human	Sf9 insect cells
	The SLC30A10 protein is a plasma membrane calcium:manganese antiporter that promotes the release of intracellular manganese and the simultaneous import of extracellular calcium. SLC30A10 Protein, Human (sf9, His, Strep, FLAG) is the recombinant human-derived SLC30A10 protein, expressed by sf9 insect cells , with N-Strep, C-Flag, N-8*His labeled tag.

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HY-W738271

Veratryl alcohol-13C

Veratryl alcohol- ¹³C (3,4-Dimethoxybenzyl alcohol- ¹³C) is the ¹³C-labeled Veratryl alcohol (HY-107858). Veratryl alcohol (3,4-Dimethoxybenzyl alcohol) is a secondary metabolite of lignin-degrading fungi, commonly used as a substrate for lignin peroxidase (LiP) to measure lignin degradation activity. Veratryl alcohol protects LiP from inactivation by H2O2 and prevents the accumulation of LiP III compounds. Veratryl alcohol also acts as a stabilizer for manganese-dependent peroxidases (MnP). Veratryl alcohol is a quorum-sensing inhibitor (QSI) and exhibits antibacterial efficacy .

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