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Results for "

Malondialdehyde

" in MedChemExpress (MCE) Product Catalog:

45

Inhibitors & Agonists

1

Fluorescent Dye

2

Peptides

2

Inhibitory Antibodies

13

Natural
Products

12

Isotope-Labeled Compounds

1

Click Chemistry

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W749411
    Malondialdehyde tetrabutylammonium

    		Biochemical Assay Reagents Endogenous Metabolite
    Malondialdehyde tetrabutylammonium is a biomarker with antioxidant activity. Malondialdehyde tetrabutylammonium can be used as an indicator of lipid peroxidation to help assess oxidative stress levels. Malondialdehyde tetrabutylammonium is widely used in the food and cosmetics fields, mainly for monitoring and evaluating product stability and safety. Malondialdehyde tetrabutylammonium has an important role in indicating cell damage and is a potential biomarker for studying a variety of diseases.
    Malondialdehyde tetrabutylammonium
  • HY-N8253
    Spiraeoside
    1 Publications Verification

    Quercetin 4′-O-glucoside

    		 Reactive Oxygen Species (ROS) Inflammation/Immunology Cancer
    Spiraeoside, an orally active natural compound, exerts antioxidant activity, inhibits reactive oxygen species (ROS) and malondialdehyde production. Spiraeoside possesses antiallergic, anti-inflammatory and antitumor activities .
    Spiraeoside
  • HY-77962
    2-Thiobarbituric acid

    		Biochemical Assay Reagents Others
    2-Thiobarbituric acid is a commonly used colorimetric reagent for the detection of malondialdehyde (MDA), a marker of lipid peroxidation. 2-Thiobarbituric acid forms a complex with MDA that can be quantified by colorimetric detection at 532 nm as a measure of lipid peroxidation .
    2-Thiobarbituric acid
  • HY-N0034
    Arctiin
    5 Publications Verification

    Arctii; NSC 315527; Arctigenin-4-glucoside

    		 NF-κB Inflammation/Immunology Cancer
    Arctiin is an orally active inhibitor of NF-κB. Arctiin suppresses cyclin D1 protein expression in human tumor cells. Arctiin also reduces malondialdehyde and pro-in ammatory cytokines levels. Arctiin can used in study glomerulonephritis .
    Arctiin
  • HY-141452
    Propanedial

    Malondialdehyde

    		 Endogenous Metabolite Neurological Disease
    Propanedial is one of the final products of lipid peroxidation that is often used to assess lipid peroxidation.
    Propanedial
  • HY-N3562
    Cedrin

    		Reactive Oxygen Species (ROS) Neurological Disease
    Cedrin is a natural flavonoid that can be found in Cedrus deodara. Cedrin protects PC12 cells against neurotoxicity induced by Aβ1-42. Cedrin can reduce reactive oxygen species overproduction, increase the activity of superoxide dismutase and decrease malondialdehyde content .
    Cedrin
  • HY-N9283
    1,2-Diacetoxy-4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzofuran

    		Reactive Oxygen Species (ROS) Neurological Disease Cancer
    1,2-Diacetoxy-4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzofuran, isolated from the edible mushroom Sarcodon leucopus, has antioxidant effects in the DPPH scavenging assay with the IC50 of 28 μM, inhibits malondialdehyde (MDA) with the IC50 of 71 μM, and inhibits α-glucosidase with the IC50 of 6.22 μM .
    1,2-Diacetoxy-4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzofuran
  • HY-P4308
    Z-Pro-Pro-aldehyde-dimethyl acetal

    		Prolyl Endopeptidase (PREP) Neurological Disease
    Z-Pro-Pro-aldehyde-dimethyl acetal is a potent inhibitor of prolyl endopeptidase (PREP), a cytoplasmic serine endoprotease (IC50= 12 nM). Z-Pro-Pro-aldehyde-dimethyl acetal plays an important role in cognitive dysfunction in aging and neurodegenerative diseases including Alzheimer's disease .
    Z-Pro-Pro-aldehyde-dimethyl acetal
  • HY-W275295
    Perfluorododecanoic acid

    PFDoA

    		 Reactive Oxygen Species (ROS) Metabolic Disease
    Perfluorododecanoic acid (PFDoA) is a perfluoroalkyl substance (PFAS) found in lake trout. Perfluorododecanoic acid decreases the viability of PC12 cells. Perfluorododecanoic acid also increases reactive oxygen species (ROS), malondialdehyde (MDA) levels and reduces the mitochondrial membrane potential in PC12 cells .
    Perfluorododecanoic acid
  • HY-N8253R
    Spiraeoside (Standard)

    Quercetin 4′-O-glucoside (Standard)

    		 Reference Standards Reactive Oxygen Species (ROS) Inflammation/Immunology Cancer
    Spiraeoside (Standard) is the analytical standard of Spiraeoside. This product is intended for research and analytical applications. Spiraeoside, an orally active natural compound, exerts antioxidant activity, inhibits reactive oxygen species (ROS) and malondialdehyde production. Spiraeoside possesses antiallergic, anti-inflammatory and antitumor activities .
    Spiraeoside (Standard)
  • HY-N8253S
    Quercetin 4'-Glucoside-d3

    Spiraeoside-d3

    		 Isotope-Labeled Compounds Reactive Oxygen Species (ROS) Inflammation/Immunology Cancer
    Quercetin 4'-Glucoside-d3 (Spiraeoside-d3) is deuterium labeled Spiraeoside. Spiraeoside, an orally active natural compound, exerts antioxidant activity, inhibits reactive oxygen species (ROS) and malondialdehyde production. Spiraeoside possesses antiallergic, anti-inflammatory and antitumor activities .
    Quercetin 4'-Glucoside-d3
  • HY-W420337
    Fluopimomide

    LH2010A

    		 Reactive Oxygen Species (ROS) Infection
    Fluopimomide (LH2010A) is a potent pesticide, widely used for agricultural pest management. Fluopimomide adversely affects the nematodes growth, locomotive behaviors, reproduction, and lifespan, accompanying with enhanced of reactive oxygen species (ROS) generation, lipid and lipofuscin accumulation, and malondialdehyde content. Fluopimomide inhibits antioxidant systems in the nematodes .
    Fluopimomide
  • HY-P99793
    Orticumab

    MLDL1278A

    		 LDLR Inflammation/Immunology
    Orticumab (MLDL1278A) is an antibody targeting to oxidized or malondialdehyde-modified lipoprotein (LDL). Orticumab specifically inhibits oxidized low-density lipoproteins (oxLDL). Orticumab involves in modulation of autoimmune responses against oxLDL, improves atherosclerosis in animal model. Orticumab also can be used for research of psoriasis improvement .
    Orticumab
  • HY-N0034R
    Arctiin (Standard)

    Arctii (Standard); NSC 315527 (Standard); Arctigenin-4-glucoside (Standard)

    		 Reference Standards NF-κB Inflammation/Immunology Cancer
    Arctiin (Standard) is the analytical standard of Arctiin. This product is intended for research and analytical applications. Arctiin is an orally active inhibitor of NF-κB. Arctiin suppresses cyclin D1 protein expression in human tumor cells. Arctiin also reduces malondialdehyde and pro-in?ammatory cytokines levels. Arctiin can used in study glomerulonephritis .
    Arctiin (Standard)
  • HY-N0717
    L-Valine
    4 Publications Verification

    (S)-Valine

    		 Bacterial Arginase Akt Infection
    L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase .
    L-Valine
  • HY-14744A
    Levamlodipine besylate
    2 Publications Verification

    (S)-Amlodipine besylate; Levoamlodipine besylate

    		 Calcium Channel SOD Cardiovascular Disease
    Levamlodipine besylate ((S)-Amlodipine besylate) is an orally active calcium channel blocker with antioxidant and vasodilatory properties. Levamlodipine besylate can reduce serum malondialdehyde (MDA) levels, increase superoxide dismutase (SOD) activity, and improve oxidative stress. Levamlodipine besylate can be used for research on vascular dementia, hypertension, and cerebrovascular diseases .
    Levamlodipine besylate
  • HY-W015012
    NBD-Hydrazine

    		Fluorescent Dye Others
    NBD-Hydrazine is an aldehyde- and ketone-reactive fluorescent probe. NBD-Hydrazine has excitation/emission maxima of 468/535 nm in the presence of aldehydes or ketones. NBD-Hydrazine can be used as a starting material to synthesize malondialdehyde-reactive fluorescent probes. NBD-Hydrazine is a synthetic intermediate in the synthesis of cupric and chronic ion colorimetric sensors .
    NBD-Hydrazine
  • HY-124894
    (+)-Benalaxyl

    		Fungal Infection
    (+)-Benalaxyl is a broad-spectrum benzamide fungicide. (+)-Benalaxyl inhibits the growth of the freshwater algae S. obliquus, with an EC50 value of 8.441 mg/L. (+)-Benalaxyl can induce the production of chlorophyll a and b, as well as increase the activity of superoxide dismutase (SOD) and the generation of malondialdehyde (MDA). (+)-Benalaxyl has inhibitory effects on catalase (CAT). (+)-Benalaxyl is effective against diseases caused by oomycetes .
    (+)-Benalaxyl
  • HY-14744C
    Levamlodipine hydrobromide

    (S)-Amlodipine hydrobromide; Levoamlodipine hydrobromide

    		 Calcium Channel SOD Cardiovascular Disease Others
    Levamlodipine hydrobromide is the besylate hydrobromide salt form of Levamlodipine (HY-14744). Levamlodipine hydrobromide is an orally active calcium channel blocker with antioxidant and vasodilatory properties. Levamlodipine hydrobromide can reduce serum malondialdehyde (MDA) levels, increase superoxide dismutase (SOD) activity, and improve oxidative stress. Levamlodipine hydrobromide can be used for research on vascular dementia, hypertension, and cerebrovascular diseases .
    Levamlodipine hydrobromide
  • HY-W117986
    Aβ aggregation-IN-1

    		Amyloid-β Neurological Disease
    Aβ aggregation-IN-1 (Compound 1b) is an amyloid-beta precursor protein inhibitor. Aβ aggregation-IN-1 inhibits amyloid-beta aggregation and disaggregation of fibrillogenesis with IC50 values of 3.92 and 7.19 M, respectively. Aβ aggregation-IN-1 also inhibits malondialdehyde formation, augments the intracellular reduced glutathione (GSH) levals and inhibits caspase 3 in neuronal cells .
    Aβ aggregation-IN-1
  • HY-14744D
    Levamlodipine besylate Hemipentahydrate

    		Calcium Channel SOD Cardiovascular Disease Neurological Disease
    Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine (HY-14744). Levamlodipine besylate hemipentahydrate is an orally active calcium channel blocker with antioxidant and vasodilatory properties. Levamlodipine besylate hemipentahydrate can reduce serum malondialdehyde (MDA) levels, increase superoxide dismutase (SOD) activity, and improve oxidative stress. Levamlodipine besylate hemipentahydrate can be used for research on vascular dementia, hypertension, and cerebrovascular diseases .
    Levamlodipine besylate Hemipentahydrate
  • HY-126758
    Ludartin

    		Apoptosis Glutathione Peroxidase Inflammation/Immunology
    Ludartin a sesquiterpene lactone, which can be isolated from the plant Artemisia carruthii Wood. Ludartin reduces the expression of myeloperoxidase and malondialdehyde, enhances the expression of glutathione and superoxide dismutase in spinal cord tissue. Ludartin inhibits neuronal apoptosis. Ludartin inhibits the upregulation of tumor necrosis factor-α, interleukin-1β, and interleukin-6. Ludartin improves the motor function of rats with spinal cord injury .
    Ludartin
  • HY-161388
    NSCLC-IN-1

    		Ferroptosis Mitophagy Cancer
    NSCLC-IN-1 (Compound A10-2) induces mitophagy and ferroptosis through targeting transmembrane BAX inhibitor motif containing 6 (TMBIM6). NSCLC-IN-1 induces mitochondrial Ca 2+ imbalance, leading to mitochondrial damage. NSCLC-IN-1 reduces intracellular glutathione (GSH), increases the accumulation of lipid peroxides (LPO) and malondialdehyde (MDA) content. NSCLC-IN-1 is a potent anti-NSCLC agent .
    NSCLC-IN-1
  • HY-N0717S
    L-Valine-15N

    (S)-Valine-15N

    		 Isotope-Labeled Compounds Arginase Akt Bacterial Infection
    L-Valine- 15N ((S)-Valine- 15N) is the 15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase .
    L-Valine-15N
  • HY-N15398
    Chaetoglobosin E

    		Ferroptosis Cancer
    Chaetoglobosin E is a Ferroptosis inducer that exhibits significant cytotoxicity against human tumor cell lines MDA-MB231 and A549, with IC50 values of 9.14 and 7.47 μM, respectively. By downregulating the expression of GPX4 in A549 cells, Chaetoglobosin E markedly increases intracellular levels of Fe 2+ and the lipid peroxidation product malondialdehyde (MDA), leading to mitochondrial shrinkage, reduction or disappearance of cristae, and subsequent induction of ferroptosis. Chaetoglobosin E can be used for research in the field of cancer .
    Chaetoglobosin E
  • HY-N0717S6
    L-Valine-13C5

    (S)-Valine-13C5

    		 Isotope-Labeled Compounds Arginase Akt Bacterial Infection
    L-Valine- 13C5 ((S)-Valine- 13C5) is the 13C-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase .
    L-Valine-13C5
  • HY-N0717R
    L-Valine (Standard)

    (S)-Valine (Standard)

    		 Reference Standards Arginase Akt Bacterial Infection
    L-Valine (Standard) ((S)-Valine (Standard)) is the analytical standard of L-Valine (HY-N0717). This product is intended for research and analytical applications. L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase .
    L-Valine (Standard)
  • HY-N0717S8
    L-Valine-d1

    (S)-Valine-d1

    		 Isotope-Labeled Compounds Arginase Akt Bacterial Infection
    L-Valine-d1 ((S)-Valine-d1) is the deuterium labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase .
    L-Valine-d1
  • HY-P991381
    JST-TfR09

    PPMX-T003

    		 Transferrin Receptor Reactive Oxygen Species (ROS) Ferroptosis Cancer
    TXB4 (PPMX-T003) is a human monoclonal antibody (mAb) targeting CD71. JST-TfR09 can induce ferroptosis by reducing ferritin levels in ATLL cell lines, increasing the generation of ferrous iron and reactive oxygen species (ROS), and inducing lipid peroxidation via malondialdehyde. JST-TfR09 can be used in leukemia research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
    JST-TfR09
  • HY-N0717S5
    L-Valine-2-13C

    (S)-Valine-13C

    		 Isotope-Labeled Compounds Arginase Akt Bacterial Infection
    L-Valine-2- 13C ((S)-Valine-2- 13C) is the 13C-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase .
    L-Valine-2-13C
  • HY-N0717S4
    L-Valine-1-13C

    (S)-Valine-1-13C

    		 Isotope-Labeled Compounds Arginase Akt Bacterial Infection
    L-Valine-1- 13C ((S)-Valine-1- 13C) is the 13C-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase .
    L-Valine-1-13C
  • HY-N0717S9
    L-Valine-15N,d8

    (S)-Valine-15N,d8

    		 Isotope-Labeled Compounds Arginase Akt Bacterial Infection
    L-Valine- 15N,d8 ((S)-Valine- 15N,d8) is the deuterium and 15N labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase .
    L-Valine-15N,d8
  • HY-133968
    24-Methylenecholesterol

    Ostreasterol

    		 Acyltransferase Reactive Oxygen Species (ROS) Inflammation/Immunology
    24-Methylenecholesterol (Ostreasterol) is a regulator targeting acyl-CoA cholesterol acyltransferase (ACAT) with anti-aging and neuroprotective effects. 24-Methylenecholesterol mimics the effects of nerve growth factor (NGF), can extend yeast lifespan through an anti-oxidative stress mechanism, and exhibits neuroprotective activity in PC12 cells. 24-Methylenecholesterol can reduce intracellular reactive oxygen species (ROS) and malondialdehyde (MDA) levels, activate anti-oxidative stress pathways (such as UTH1, SOD-related genes), and promote synaptic growth .
    24-Methylenecholesterol
  • HY-N0717S1
    L-Valine-13C5,15N

    (S)-Valine-13C5,15N

    		 Isotope-Labeled Compounds Arginase Akt Bacterial Infection
    L-Valine- 13C5, 15N ((S)-Valine- 13C5, 15) is the 13C- and 15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase .
    L-Valine-13C5,15N
  • HY-N0717S7
    L-Valine-1-13C,15N

    (S)-Valine-1-13C,15N

    		 Isotope-Labeled Compounds Arginase Akt Bacterial Infection
    L-Valine-1- 13C, 15N ((S)-Valine-1- 13C, 15N) is the 13C- and 15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase .
    L-Valine-1-13C,15N
  • HY-145453
    Propacetamol

    		Interleukin Related Inflammation/Immunology
    Propacetamol is an orally active prodrug of Acetaminophen (HY-66005), which exerts antipyretic and analgesic effects after metabolism. Propacetamol reduces Aspirin (ASA) (HY-14654)-induced elevation of malondialdehyde (MDA) in gastric mucosa and plasma, regulates the levels of gastric mucosal glutathione (GSH and GSSG) to maintain cellular antioxidant defense, and increases gastric mucosal uric acid (UA) levels. Propacetamol exerts a dose-dependent protective effect against ASA-induced gastric mucosal damage in rats. Propacetamol can be used for the study of gastric mucosal injury by interfering with oxidative stress .
    Propacetamol
  • HY-N0717S2
    L-Valine-13C5,15N,d8

    (S)-Valine-13C5,15N,d8

    		 Isotope-Labeled Compounds Arginase Akt Bacterial Infection
    L-Valine- 13C5, 15N,d8 ((S)-Valine- 13C5, 15N,d8) is the deuterium, 13C-, and 15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase .
    L-Valine-13C5,15N,d8
  • HY-N0717S3
    L-Valine-13C5,15N,d2

    (S)-Valine-13C5,15N,d2

    		 Isotope-Labeled Compounds Arginase Akt Bacterial Infection
    L-Valine- 13C5, 15N,d2 ((S)-Valine- 13C5, 15N,d2) is the deuterium, 13C-, and 15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase .
    L-Valine-13C5,15N,d2
  • HY-34350
    2-(Aminomethyl)phenol

    2-Hydroxybenzylamine; o-Hydroxybenzylamine; 2-HOBA

    		 Reactive Oxygen Species (ROS) Cardiovascular Disease Inflammation/Immunology
    2-(Aminomethyl)phenol (2-Hydroxybenzylamine) is a selective dicarbonyl scavenger. 2-(Aminomethyl)phenol is an antioxidant and scavanger of free radicals and isolevuglandins (IsoLGs). 2-(Aminomethyl)phenol can prevent early recurrence of atrial fibrillation. 2-(Aminomethyl)phenol can reduce inflammation and plaque apoptotic cells and promote efferocytosis and features of stable plaques. 2-(Aminomethyl)phenol can reduce malondialdehyde (MDA)-LDL and MDA-HDL levels in Ldlr -/- mouse model. 2-(Aminomethyl)phenol can be studied in the research of inflammation and cardiovascular disease, such as atherosclerosis, early recurrence of atrial fibrillation (AF) and arrhythmias .
    2-(Aminomethyl)phenol
  • HY-17655
    TBE56

    		Reactive Oxygen Species (ROS) Inflammation/Immunology
    TBE56, a molecular glue, is a BACH1 degrader, with an EC50 of 44 nM. TBE56 is a weak NRF2 inducer and the biotinylated TBE31. TBE56 interacts and promotes the degradation of BACH1 via a mechanism involving the E3 ligase FBX022. TBE56 reduces intracellular Fe 2+ accumulation, ROS generation, and malondialdehyde (MDA) content, while increasing GSH/GSSG ratio and upregulating GPX4 in Prominin-2-overexpressed BMSCs. TBE56 significantly ameliorates intervertebral disc degeneration (IVDD) in puncture-induced SD rat IVDD model. TBE56 can be used for the study of intervertebral disc degeneration (IVDD) .
    TBE56
  • HY-133968S1
    24-Methylenecholesterol-13C

    Ostreasterol-13C

    		 Isotope-Labeled Compounds Acyltransferase Reactive Oxygen Species (ROS) Inflammation/Immunology
    24-Methylenecholesterol- 13C (Ostreasterol- 13C) is the 13C labeled 24-Methylenecholesterol (HY-133968) . 24-Methylenecholesterol (Ostreasterol) is a regulator targeting acyl-CoA cholesterol acyltransferase (ACAT) with anti-aging and neuroprotective effects. 24-Methylenecholesterol mimics the effects of nerve growth factor (NGF), can extend yeast lifespan through an anti-oxidative stress mechanism, and exhibits neuroprotective activity in PC12 cells. 24-Methylenecholesterol can reduce intracellular reactive oxygen species (ROS) and malondialdehyde (MDA) levels, activate anti-oxidative stress pathways (such as UTH1, SOD-related genes), and promote synaptic growth .
    24-Methylenecholesterol-13C
  • HY-133968R
    24-Methylenecholesterol (Standard)

    Ostreasterol (Standard)

    		 Reference Standards Acyltransferase Reactive Oxygen Species (ROS) Inflammation/Immunology
    24-Methylenecholesterol (Ostreasterol) (Standard) is the analytical standard of 24-Methylenecholesterol (HY-133968). This product is intended for research and analytical applications. 24-Methylenecholesterol (Ostreasterol) is a regulator targeting acyl-CoA cholesterol acyltransferase (ACAT) with anti-aging and neuroprotective effects. 24-Methylenecholesterol mimics the effects of nerve growth factor (NGF), can extend yeast lifespan through an anti-oxidative stress mechanism, and exhibits neuroprotective activity in PC12 cells. 24-Methylenecholesterol can reduce intracellular reactive oxygen species (ROS) and malondialdehyde (MDA) levels, activate anti-oxidative stress pathways (such as UTH1, SOD-related genes), and promote synaptic growth .
    24-Methylenecholesterol (Standard)
  • HY-145453R
    Propacetamol (Standard)

    		Reference Standards Interleukin Related Inflammation/Immunology
    Propacetamol (Standard) is the analytical standard of Propacetamol (HY-145453). This product is intended for research and analytical applications. Propacetamol is an orally active prodrug of Acetaminophen (HY-66005), which exerts antipyretic and analgesic effects after metabolism. Propacetamol reduces Aspirin (ASA) (HY-14654)-induced elevation of malondialdehyde (MDA) in gastric mucosa and plasma, regulates the levels of gastric mucosal glutathione (GSH and GSSG) to maintain cellular antioxidant defense, and increases gastric mucosal uric acid (UA) levels. Propacetamol exerts a dose-dependent protective effect against ASA-induced gastric mucosal damage in rats. Propacetamol can be used for the study of gastric mucosal injury by interfering with oxidative stress .
    Propacetamol (Standard)
  • HY-175852
    Ferroptosis inducer-11

    		Ferroptosis Glutathione Peroxidase Reactive Oxygen Species (ROS) Cancer
    Ferroptosis inducer-11 is a ferroptosis inducer. Ferroptosis inducer-11 exhibits potent cytotoxicity against HCT-116, NCM-60 and HT-29 cells with IC50 values of 0.43 μM, 3.14 μM and 0.48 μM, respectively. Ferroptosis inducer-11 strongly suppresses GPX4 enzymatic activity with an IC50 of 1.86 μM. Ferroptosis inducer-11 induces ferroptosis, as well as increases intracellular lipid ROS, malondialdehyde (MDA), and Fe 2+ levels, while decreasing glutathione (GSH) levels in colon cancer cells. Ferroptosis inducer-11 can be used for the study of colon cancer .
    Ferroptosis inducer-11
  • HY-175041
    GPX4-IN-18

    		Glutathione Peroxidase Reactive Oxygen Species (ROS) Cannabinoid Receptor Ferroptosis Cancer
    GPX4-IN-18 (Compound 17) is a ferrocene-containing inhibitor of glutathione peroxidase 4 (GPX4). GPX4-IN-18 is also an inducer of ferroptosis. GPX4-IN-18 can increase the production of ROS and malondialdehyde (MDA) levels in OS-RC-2 clear cell renal cell carcinoma cells. GPX4-IN-18 induces ferroptosis in HT-1080 cells with IC50s of 0.007 μM (absence of ferrostatin-1) and 1.486 μM (presence of ferrostatin-1). GPX4-IN-18 reduces in vivo tumor volume and intratumoral GPX4 levels in OS-RC-2 xenograft murine model .
    GPX4-IN-18

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