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Results for "

MRP4

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Fluorescent Dye (1) Leukotriene Receptor (2) LPL Receptor (4) OAT (1) P-glycoprotein (8) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Inflammation/Immunology (4) Metabolic Disease (4)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Natural
Products

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101453

Ceefourin 1	P-glycoprotein	Cancer
Ceefourin 1 is a potent and highly selective multidrug resistance protein 4 (MRP4) inhibitor. Ceefourin 1 inhibits transport of a broad range of MRP4 substrates, yet is highly selective for MRP4 over other ABC transporters. Ceefourin 1 is a benzothiazol and primarily as a chemosensitizer for high-risk neuroblastoma .

HY-136217

PU 23	P-glycoprotein	Cancer
PU 23 is a non-carboxylic multidrug resistance protein 4 (MRP4) inhibitor as an active agent reducing resistance to anticancer agent 6-Mercaptopurine .

HY-19989A

MK-571 sodium Maximum Cited Publications 28 Publications Verification L-660711 sodium	P-glycoprotein LPL Receptor Leukotriene Receptor	Inflammation/Immunology
MK-571 (L-660711) sodium is an orally active, potent and selective competitive *leukotriene D₄ (LTD₄)* receptor antagonist, with K_i values of 0.22 and 2.1 nM in guinea pig and human lung membranes, respectively. MK-571 sodium is also a inhibitor of multidrug resistance-associated protein MRP4 (ABCC4)** and ABCC1 (MRP1). MK-571 sodium inhibits constitutive and antigen-stimulated S1P (sphingosine-1-phosphate) release .

HY-100619A

BMS-986020 sodium 5+ Cited Publications AM152 sodium	LPL Receptor	Metabolic Disease Inflammation/Immunology
BMS-986020 (AM152) sodium is a high-affinity lysophosphatidic acid receptor 1 (LPA1) antagonist . BMS-986020 sodium inhibits bile acid and phospholipid transporters with IC₅₀s of 4.8 μM, 6.2 μM, and 7.5 μM for BSEP, MRP4, and MDR3, respectively . BMS-986020 sodium has the potential for the treatment of idiopathic pulmonary fibrosis (IPF) .

HY-100619

BMS-986020 5+ Cited Publications AM152	LPL Receptor	Metabolic Disease Inflammation/Immunology
BMS-986020 (AM152) is a high-affinity and selective lysophosphatidic acid receptor 1 (LPA1) antagonist . BMS-986020 inhibits bile acid and phospholipid transporters with IC₅₀s of 4.8 μM, 6.2 μM, and 7.5 μM for BSEP, MRP4, and MDR3, respectively . BMS-986020 has the potential for the treatment of idiopathic pulmonary fibrosis (IPF) .

HY-19989

MK-571 Maximum Cited Publications 28 Publications Verification L-660711	P-glycoprotein LPL Receptor Leukotriene Receptor	Inflammation/Immunology
MK-571 (L-660711) is an orally active, potent and selective competitive *leukotriene D₄ (LTD₄)* receptor antagonist, with K_i values of 0.22 and 2.1 nM in guinea pig and human lung membranes, respectively. MK-571 is also a MRP4** and ABCC1 (MRP1) inhibitor. MK-571 inhibits constitutive and antigen-stimulated S1P (sphingosine-1-phosphate) release .

HY-122009

Indican Indoxyl-β-D-glucoside	P-glycoprotein OAT Fluorescent Dye	Others
Indican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter (OAT) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4 .

HY-121088

Ceefourin 2	P-glycoprotein	Cardiovascular Disease Others
Ceefourin 2 is a potent and highly selective inhibitor of *MRP4. Ceefourin 2 inhibits the transport of MRP4* substrates but is not selective for other ABC transporters. Ceefourin 2 shows lower cytotoxicity and higher microsomal and acid stability .

HY-W702908

DM-4107	P-glycoprotein	Metabolic Disease
DM-4107 is a major metabolite of Tolvaptan (HY-17000) that is metabolized primarily by the CYP3A4 enzyme in the liver. DM-4107 inhibits the ability of human liver transporters NTCP, BSEP, MRP3, MRP4 (IC₅₀ values are 95.6, 119, 61.2, 37.9 μM, respectively) and bile acid transport in SCHH cells. DM-4107 can be used in the study of autosomal dominant polycystic kidney disease (ADPKD) .

HY-W702907

DM-4103	P-glycoprotein	Metabolic Disease
DM-4103 is a major metabolite of Tolvaptan (HY-17000) that is metabolized primarily by the CYP3A4 enzyme in the liver. DM-4103 inhibits the ability of human liver transporters NTCP, BSEP, MRP2, MRP3, MRP4 (IC₅₀ values are 16.3, 4.15, 51.0, 44.6, 4.26 μM, respectively) and bile acid transport in SCHH cells. DM-4103 can be used in the study of autosomal dominant polycystic kidney disease (ADPKD) .

HY-RS26864

Abcc4 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Abcc4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Abcc4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Abcc4 Rat Pre-designed siRNA Set A Abcc4 Rat Pre-designed siRNA Set A

HY-RS00063

ABCC4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
ABCC4 Human Pre-designed siRNA Set A contains three designed siRNAs for ABCC4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

ABCC4 Human Pre-designed siRNA Set A ABCC4 Human Pre-designed siRNA Set A

HY-RS20355

Abcc4 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Abcc4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Abcc4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Abcc4 Mouse Pre-designed siRNA Set A Abcc4 Mouse Pre-designed siRNA Set A

Indican Indoxyl-β-D-glucoside	Alkaloids Structural Classification Classification of Application Fields Leguminosae Source classification Other Diseases Plants Disease Research Fields Indole Alkaloids Indigofera	P-glycoprotein OAT Fluorescent Dye
Indican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter (OAT) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4 .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81421

	MRP4 Antibody (YA1166) MRP4; MOATB; MOAT-B; EST170205	IHC-P	Human
	MRP4 Antibody (YA1166) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1166), targeting MRP4. MRP4 Antibody (YA1166) can be used for IHC-P experiment in human background.

HY-P83833

	ABCC4 Antibody (YA3530) MRP4; MOATB; MOAT-B; EST170205	IHC-P, FC, ELISA	Human
	ABCC4 Antibody (YA3530) is a mouse-derived and non-conjugated IgG1 antibody, targeting to ABCC4. It can be applicated for IHC-P, FC, ELISA assays, in the background of human.

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Abcc4 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Abcc4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Abcc4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

ABCC4 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ABCC4 Human Pre-designed siRNA Set A contains three designed siRNAs for ABCC4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Abcc4 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Abcc4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Abcc4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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