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Pathways Recommended: Stem Cell/Wnt Cell Cycle/DNA Damage
Results for "

MDA-MB-157 cells

" in MedChemExpress (MCE) Product Catalog:
Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162531
    KIF18A-IN-9

    		Kinesin Microtubule/Tubulin Cancer
    KIF18A-IN-9 (Compound 1) is a potent KIF18A inhibitor, with an IC50 value of 3.8 nM. KIF18A-IN-9 has anticancer activity, with IC50 values of less than 100 nM in OVCAR3 and MDA-MB-157 cells .
    KIF18A-IN-9
  • HY-176444B
    (S)-CDK2 degrader 6

    		CDK Molecular Glues Cancer
    (S)-CDK2 degrader 6 (Compound 8) is the S-enantiomer of CDK2 degrader 6 (HY-176444). (S)-CDK2 degrader 6 is a selective CDK2 molecular glue degrader with a DC50 of 166.7 nM in 24 h. (S)-CDK2 degrader 6 can be used for breast cancer research .
    (S)-CDK2 degrader 6
  • HY-176444A
    (R)-CDK2 degrader 6

    		CDK Molecular Glues Cancer
    (R)-CDK2 degrader 6 (Compound 7) is the R-enantiomer of CDK2 degrader 6 (HY-176444). (R)-CDK2 degrader 6 is a selective CDK2 molecular glue degrader with a DC50 of 27.0 nM in 24 h. (R)-CDK2 degrader 6 can be used for breast cancer research .
    (R)-CDK2 degrader 6
  • HY-158683
    KIF18A-IN-11

    		Kinesin Microtubule/Tubulin Cancer
    KIF18A-IN-11 (Compound 13) is a potent KIF18A inhibitor, with IC50 values of less than 100 nM in OVCAR3 and MDA-MB-157 cells. KIF18A-IN-11 can be used for the research of cancer .
    KIF18A-IN-11
  • HY-172957
    JNN-5

    		JAK Cancer
    JNN-5 is a potent and selective JAK2 inhibitor with an IC50 of 0.41 nM. JNN-5 shows strong antiproliferative activities in the TNBC cell lines (MDA-MB-468, MDA-MB-213, HCC70, MDA-MB-157) .
    JNN-5
  • HY-162532
    KIF18A-IN-10

    		Kinesin Microtubule/Tubulin Cancer
    KIF18A-IN-10 (Compound 24) is a potent KIF18A inhibitor, with an IC50 value of 23.8 nM. KIF18A-IN-10 has anticancer activity, with IC50 values of less than 100 nM in OVCAR3 and MDA-MB-157 cells .
    KIF18A-IN-10

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