2. Cell Cycle/DNA Damage PROTAC
  3. CDK Molecular Glues
  4. (R)-CDK2 degrader 6

(R)-CDK2 degrader 6 (Compound 7) is the R-enantiomer of CDK2 degrader 6 (HY-176444). (R)-CDK2 degrader 6 is a selective CDK2 molecular glue degrader with a DC50 of 27.0 nM in 24 h. (R)-CDK2 degrader 6 can be used for breast cancer research.

For research use only. We do not sell to patients.

(R)-CDK2 degrader 6

(R)-CDK2 degrader 6 Chemical Structure

CAS No. : 3083777-50-5

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(R)-CDK2 degrader 6 Related Antibodies

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Description

(R)-CDK2 degrader 6 (Compound 7) is the R-enantiomer of CDK2 degrader 6 (HY-176444). (R)-CDK2 degrader 6 is a selective CDK2 molecular glue degrader with a DC50 of 27.0 nM in 24 h. (R)-CDK2 degrader 6 can be used for breast cancer research[1].

IC50 & Target[1]

CDK2

27 nM (DC50)

Molecular Weight

511.44

Formula

C23H22F5N5O3
CAS No.
SMILES

FC(F)(C12CC(C2)(C3=NN=C(N[C@@H]4[C@H](N(C5=CC(F)=C([C@@H]6C(NC(CC6)=O)=O)C(F)=C5)C4)C)O3)C1)F
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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(R)-CDK2 degrader 6 Related Classifications

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Keywords:

(R)-CDK2 degrader 63083777-50-5CDKMolecular GluesCyclin dependent kinaseR-enantiomerCDK2Molecular glue degraderMDA-MB-157 cellsBreast cancerInhibitorinhibitorinhibit

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(R)-CDK2 degrader 6
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