2. PROTAC Cell Cycle/DNA Damage
  3. Molecular Glues CDK
  4. CDK2 degrader 6

CDK2 degrader 6 (compound 6) is an orally active and potent CDK2 molecular glue degrader with a DC50 of 46.5 nM. CDK2 degrader 6 can be used in the study of breast cancer.

For research use only. We do not sell to patients.

CDK2 degrader 6

CDK2 degrader 6 Chemical Structure

CAS No. : 3036606-92-2

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Based on 1 publication(s) in Google Scholar

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CDK2 degrader 6 Related Antibodies

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Description

CDK2 degrader 6 (compound 6) is an orally active and potent CDK2 molecular glue degrader with a DC50 of 46.5 nM. CDK2 degrader 6 can be used in the study of breast cancer[1].

Molecular Weight

511.44

Formula

C23H22F5N5O3
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(C(CC1)C2=C(F)C=C(N3C[C@H](NC4=NN=C(C56CC(C6)(C(F)(F)F)C5)O4)[C@H]3C)C=C2F)NC1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Purity & Documentation
References
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CDK2 degrader 6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CDK2 degrader 63036606-92-2Molecular GluesCDKCyclin dependent kinasecyclin-dependent kinase 2CDK2MDA-MB-157breast cancerInhibitorinhibitorinhibit

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CDK2 degrader 6
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