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LNSMGQD

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P11017

    p38 MAPK Inflammation/Immunology
    LNSMGQD is a peptide that targets the adhesion interface of desmoglein DSG1 and DSG3, and interferes with the DSG trans-interaction single peptide (SP) component. LNSMGQD blocks autoantibody-induced loss of DSG trans-interactions by binding to DSGs, inhibiting p38 MAPK activation and keratin filament retraction. LNSMGQD can be used to study autoimmune skin diseases such as pemphigus vulgaris .
    LNSMGQD

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