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Results for "

L-amino

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (2) Amino Acid Oxidase (1) 5-HT Receptor (1) Amyloid-β (5) Antibiotic (1) Autophagy (10) Bacterial (1) COMT (1) Dopamine Receptor (1) Drug Isomer (1) Drug Metabolite (9) Endogenous Metabolite (16) Endothelin Receptor (2) ERK (4) GCGR (1) GnRH Receptor (1) Isotope-Labeled Compounds (8) Melanocortin Receptor (1) Parasite (2) Pyruvate Kinase (4) Radionuclide-Drug Conjugates (RDCs) (2) Reference Standards (3) Renin (1) Somatostatin Receptor (3)
By Research Areas:	Cancer (15) Cardiovascular Disease (2) Endocrinology (2) Infection (2) Inflammation/Immunology (1) Metabolic Disease (18) Neurological Disease (20)

By Targets:

Amino Acid Derivatives (2)

Amino Acid Oxidase (1)

5-HT Receptor (1)

Amyloid-β (5)

Antibiotic (1)

Autophagy (10)

Bacterial (1)

COMT (1)

Dopamine Receptor (1)

Drug Isomer (1)

Drug Metabolite (9)

Endogenous Metabolite (16)

Endothelin Receptor (2)

ERK (4)

GCGR (1)

GnRH Receptor (1)

Isotope-Labeled Compounds (8)

Melanocortin Receptor (1)

Parasite (2)

Pyruvate Kinase (4)

Radionuclide-Drug Conjugates (RDCs) (2)

Reference Standards (3)

Renin (1)

Somatostatin Receptor (3)

By Research Areas:

Cancer (15)

Cardiovascular Disease (2)

Endocrinology (2)

Infection (2)

Inflammation/Immunology (1)

Metabolic Disease (18)

Neurological Disease (20)

Inhibitors & Agonists

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: Amino Acid Decarboxylase Amino Acid Oxidase Amino acid Transporter Amino Acid Derivatives EAAT

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P2987

L-Amino acid oxidase	Endogenous Metabolite Amino Acid Oxidase	Metabolic Disease
L-Amino acid oxidase is a homodimeric proteins containing flavin adenine dinucleotide. L-Amino acid oxidase can catalyze the stereospecific oxidative deamination of L-amino acids to α-keto acids and ammonia .

HY-W072147

Fmoc-Ser-OMe Fmoc-L-Ser-OMe	Amino Acid Derivatives	Others
Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected with a 9-fluorenylmethyloxycarbonyl (Fmoc) group. Fmoc-Ser-OMe involves in chlorophyll–amino acid conjugates synthesis, and acts as a chromo/fluorophores modified protein and emits visible to near-infrared lights efficiently. Fmoc-Ser-OMe glycosylates and produces small mucin-related Olinked glycopeptides, as an alcohol acceptor .

HY-N0384

Homovanillic acid Vanilacetic acid	Drug Metabolite Endogenous Metabolite Autophagy	Metabolic Disease
Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-P10474

RYTVELA	Drug Isomer	Others
RYTVELA is a deriviative of the peptide antagonist of interleukin-1 receptor 1 (IL-1R1) d-(RYTVELA) (HY-P10353) that contains all L-amino acids .

HY-N0384R

Homovanillic acid (Standard) Vanilacetic acid (Standard)	Reference Standards Autophagy Endogenous Metabolite Drug Metabolite	Neurological Disease Metabolic Disease
Homovanillic acid (Standard) (Vanilacetic acid (Standard)) is the analytical standard of Homovanillic acid (HY-N0384). This product is intended for research and analytical applications. Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S2

Homovanillic acid-d5 Vanilacetic acid-d₅	Isotope-Labeled Compounds Autophagy Endogenous Metabolite Drug Metabolite	Neurological Disease Metabolic Disease
Homovanillic acid-d₅ (Vanilacetic acid-d₅) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S

Homovanillic acid-d3 Vanilacetic acid-d₃	Isotope-Labeled Compounds Autophagy Endogenous Metabolite Drug Metabolite	Neurological Disease Metabolic Disease
Homovanillic acid-d₃ (Vanilacetic acid-d₃) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-P10110

*retro-inverso TAT-Beclin 1 (D-amino* acid)**	Autophagy	Neurological Disease
retro-inverso TAT-Beclin 1 D-amino acid is has higher activity and resistance to proteolytic degradation in vivo compared to L-amino acids peptide. TAT-Beclin 1 can induce autophagy in peripheral tissues in adult mice as well as in the central nervous system of neonatal mice .

HY-W777477

Homovanillic Acid-13C6 Vanilacetic acid-¹³C₆	Isotope-Labeled Compounds Autophagy Drug Metabolite Endogenous Metabolite	Metabolic Disease
Homovanillic Acid- ¹³C₆ (Vanilacetic acid- ¹³C₆) is the ¹³C-labeled Homovanillic acid (HY-N0384). Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.

HY-122968

Brocresine NSD-1065	Endogenous Metabolite	Neurological Disease
Brocresine (NSD-1065) is an orally active histidine decarboxylase inhibitor and inhibits the formation of histamine from histidine. Brocresine is also a L-amino acid decarboxylase inhibitor with both a peripheral and central action. Brocresine inhibits gastric secretory response to administration of exogenous gastrin .

HY-N0384S1

Homovanillic acid-d2 Vanilacetic acid-d₂	Isotope-Labeled Compounds Autophagy Endogenous Metabolite Drug Metabolite	Neurological Disease Metabolic Disease
Homovanillic acid-d₂ (Vanilacetic acid-d₂) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S4

Homovanillic acid-d3-1 Vanilacetic acid-d₃-1	Isotope-Labeled Compounds Autophagy Endogenous Metabolite Drug Metabolite	Neurological Disease Metabolic Disease
Homovanillic acid-d₃-1 (Vanilacetic acid-d₃-1) is deuterated labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-121275

Benserazide Ro 4-4602	Pyruvate Kinase	Neurological Disease Cancer
Benserazide is an *aromatic L-amino* acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor. Benserazide is also a PKM2** inhibitor. Benserazide directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide can be used for the study of Parkinson's disease and melanoma .

HY-P2965

L-Lysine α-oxidase	Endogenous Metabolite	Cancer
L-Lysine α-oxidase is a potent anticancer agent. L-Lysine α-oxidase also a L-amino acid oxidase, deaminates L-lysine with the yield of H2O2, ammonia, and α-keto-ε-aminocaproate. L-Lysine α-oxidase shows cytotoxicity and anticancer activity .

HY-B0404A

Benserazide hydrochloride Maximum Cited Publications 6 Publications Verification Ro 4-4602 hydrochloride	Pyruvate Kinase	Neurological Disease Cancer
Benserazide hydrochloride (Serazide) is an *aromatic L-amino* acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor. Benserazide hydrochloride is also a PKM2** inhibitor. Benserazide hydrochloride directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide hydrochloride can be used for the study of Parkinson's disease and melanoma .

HY-N0384S3

Homovanillic acid-13C6,18O Vanilacetic acid-¹³C₆,¹⁸O	Isotope-Labeled Compounds Autophagy Endogenous Metabolite Drug Metabolite	Neurological Disease Metabolic Disease
Homovanillic acid- ¹³C₆, ¹⁸O (Vanilacetic acid- ¹³C₆, ¹⁸O) is the ¹³C- and ¹⁸O-labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-A0282

L-Ornithine L-aspartate	Amino Acid Derivatives	Metabolic Disease Inflammation/Immunology
L-Ornithine L-aspartate is a stable salt of two natural nonessential L-amino acids with oral activity: ornithine and aspartic acid. L-Ornithine L-aspartate lowers blood ammonia concentration and to eliminate symptoms of hepatic encephalopathy associated with liver cirrhosis. L-Ornithine L-aspartate also improves mitochondrial functions .

HY-N0384S5

Homovanillic acid-13C,d3 Vanilacetic acid-¹³C,d₃	Isotope-Labeled Compounds Autophagy Endogenous Metabolite Drug Metabolite	Neurological Disease Metabolic Disease
Homovanillic acid- ¹³C,d₃ (Vanilacetic acid- ¹³C,d₃) is ¹³C and deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-P10135

RES-701-1	Endothelin Receptor	Cardiovascular Disease
RES-701-1 is a cyclic peptide composed of 16 common L-amino acids, acting as a specific antagonist for the ET_B receptor. RES-701-1 can inhibit the binding of 125I-ET-1 (125I-labeled Endothelin (ET)-1) to the ET_B receptor, with an IC₅₀ value of 10 nM .

HY-W012264

3-O-Methyldopa monohydrate 1 Publications Verification 3-Methoxy-L-tyrosine monohydrate; 3-O-Methyl-L-DOPA monohydrate	COMT	Neurological Disease
3-O-Methyldopa monohydrate (3-Methoxy-L-tyrosine monohydrate) is a significant metabolite of L-DOPA produced through the action of catechol O-methyltransferase (COMT). Unlike its precursor, 3-O-Methyldopa does not serve as a substrate or inhibitor of L-amino acid decarboxylase activity. Additionally, the inhibition of COMT can amplify the anti-Parkinson effects of L-DOPA.

HY-W011727

Pyridoxal 5'-phosphate hydrate 2 Publications Verification Pyridoxal phosphate hydrate	Endogenous Metabolite Amyloid-β ERK	Neurological Disease Metabolic Disease Cancer
Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .

HY-W011727A

Pyridoxal 5'-phosphate monohydrate 2 Publications Verification Pyridoxal phosphate monohydrate	Endogenous Metabolite Amyloid-β ERK	Neurological Disease Metabolic Disease Cancer
Pyridoxal 5'-phosphate monohydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate monohydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP) .

HY-B0404AS

Benserazide-d3 hydrochloride Ro 4-4602-d₃ hydrochloride	Isotope-Labeled Compounds Pyruvate Kinase	Neurological Disease Cancer
Benserazide-d₃ (hydrochloride) is the deuterium labeled Benserazide hydrochloride (HY-B0404A). Benserazide hydrochloride (Serazide) is an *aromatic L-amino* acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor. Benserazide hydrochloride is also a PKM2** inhibitor. Benserazide hydrochloride directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide hydrochloride can be used for the study of Parkinson's disease and melanoma .

HY-B0404AR

Benserazide hydrochloride (Standard) Ro 4-4602 hydrochloride (Standard)	Reference Standards Pyruvate Kinase	Neurological Disease Cancer
Benserazide hydrochloride (Standard) (Serazide (Standard)) is the analytical standard of Benserazide hydrochloride (HY-B0404A). This product is intended for research and analytical applications. Benserazide hydrochloride (Serazide) is an *aromatic L-amino* acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor. Benserazide hydrochloride is also a PKM2** inhibitor. Benserazide hydrochloride directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide hydrochloride can be used for the study of Parkinson's disease and melanoma .

HY-P2075

EMD 55068	Renin	Endocrinology
EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate .

HY-P11004

A3-APO	Bacterial Antibiotic	Infection
A3-APO is an antimicrobial peptide. A3-APO has a significant antimicrobial activity by a dual mode of action with both membrane disintegration and intracellular target inhibition. A3-APO can deactivate bacterial toxins and increase the expression of anti-inflammatory cytokines (such as IL-4 and IL-10), without antimicrobial resistance. A3-APO accelerates burn wounds healing in mice infection model of Acinetobacter baumannii and Staphylococcus aureus .

HY-W011727S

Pyridoxal Phosphate-d3 Pyridoxal 5'-phosphate-d₃	Endogenous Metabolite Amyloid-β ERK	Neurological Disease Metabolic Disease Cancer
Pyridoxal Phosphate-d₃ is the deuterium labeled Pyridoxal 5'-phosphate. Pyridoxal 5'-phosphate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .

HY-W011727AR

Pyridoxal 5'-?phosphate monohydrate (Standard) Pyridoxal phosphate monohydrate (Standard)	Reference Standards Endogenous Metabolite Amyloid-β ERK	Neurological Disease Metabolic Disease Cancer
Pyridoxal 5'-phosphate (monohydrate) (Standard) is the analytical standard of Pyridoxal 5'-phosphate (monohydrate). This product is intended for research and analytical applications. Pyridoxal 5'-phosphate monohydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate monohydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .

HY-P2336A

CCZ01048 TFA 3 Publications Verification	Melanocortin Receptor	Cancer
CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a K_i of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .

HY-N7512

Asimilobine	Dopamine Receptor 5-HT Receptor Parasite	Infection Cancer
Asimilobine is an aporphine isoquinoline alkaloid isolated from plant species of Magnolia obobata Thun. Asimilobine is a dopamine biosynthesis inhibitor and a serotonergic receptor antagonist. Asimilobine shows an antimalarial and anti-cancer activity .

HY-P10472

Azaline B	GnRH Receptor	Endocrinology
Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC₅₀ of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-P10341

ZP3022	GCGR	Metabolic Disease
ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .

HY-P10876

mcK6A1	Amyloid-β	Neurological Disease
mcK6A1 is an inhibitor for the aggregation of amyloid-β (Aβ), that selectively binds to the 16KLVFFA21 segment of Aβ42, forms an extended β-folded structure, and inhibits the formation of Aβ42 oligomers. mcK6A1 can be used in research of Alzheimer's disease and other amyloid-related diseases .

HY-P2434

AP102	Somatostatin Receptor	Neurological Disease Metabolic Disease Cancer
AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC₅₀: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .

HY-P5362A

NODAGA-LM3 TFA	Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor	Cancer
NODAGA-LM3 TFA can be labeled by ⁶⁸Ga for PET imaging. ⁶⁸Ga-NODAGA-LM3 TFA is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas. NODAGA-LM3 TFA can be labeled with [68Ga] for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .

HY-P5362

NODAGA-LM3	Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor	Cancer
NODAGA-LM3 can be labeled by ⁶⁸Ga for PET imaging. ⁶⁸Ga-NODAGA-LM3 is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas. NODAGA-LM3 can be labeled with [68Ga] for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .

HY-105168

TAK 044	Endothelin Receptor	Cardiovascular Disease
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .

Cat. No.	Product Name	Target	Research Area

HY-W072147

Fmoc-Ser-OMe Fmoc-L-Ser-OMe	Amino Acid Derivatives	Others
Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected with a 9-fluorenylmethyloxycarbonyl (Fmoc) group. Fmoc-Ser-OMe involves in chlorophyll–amino acid conjugates synthesis, and acts as a chromo/fluorophores modified protein and emits visible to near-infrared lights efficiently. Fmoc-Ser-OMe glycosylates and produces small mucin-related Olinked glycopeptides, as an alcohol acceptor .

HY-P10474

RYTVELA	Drug Isomer	Others
RYTVELA is a deriviative of the peptide antagonist of interleukin-1 receptor 1 (IL-1R1) d-(RYTVELA) (HY-P10353) that contains all L-amino acids .

HY-P2336A

CCZ01048 TFA 3 Publications Verification	Melanocortin Receptor	Cancer
CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a K_i of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .

HY-P10341

ZP3022	GCGR	Metabolic Disease
ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .

HY-P10110

*retro-inverso TAT-Beclin 1 (D-amino* acid)**	Autophagy	Neurological Disease
retro-inverso TAT-Beclin 1 D-amino acid is has higher activity and resistance to proteolytic degradation in vivo compared to L-amino acids peptide. TAT-Beclin 1 can induce autophagy in peripheral tissues in adult mice as well as in the central nervous system of neonatal mice .

HY-P10135

RES-701-1	Endothelin Receptor	Cardiovascular Disease
RES-701-1 is a cyclic peptide composed of 16 common L-amino acids, acting as a specific antagonist for the ET_B receptor. RES-701-1 can inhibit the binding of 125I-ET-1 (125I-labeled Endothelin (ET)-1) to the ET_B receptor, with an IC₅₀ value of 10 nM .

HY-P2075

EMD 55068	Renin	Endocrinology
EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate .

HY-P11004

A3-APO	Bacterial Antibiotic	Infection
A3-APO is an antimicrobial peptide. A3-APO has a significant antimicrobial activity by a dual mode of action with both membrane disintegration and intracellular target inhibition. A3-APO can deactivate bacterial toxins and increase the expression of anti-inflammatory cytokines (such as IL-4 and IL-10), without antimicrobial resistance. A3-APO accelerates burn wounds healing in mice infection model of Acinetobacter baumannii and Staphylococcus aureus .

HY-P10472

Azaline B	GnRH Receptor	Endocrinology
Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC₅₀ of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-P10876

mcK6A1	Amyloid-β	Neurological Disease
mcK6A1 is an inhibitor for the aggregation of amyloid-β (Aβ), that selectively binds to the 16KLVFFA21 segment of Aβ42, forms an extended β-folded structure, and inhibits the formation of Aβ42 oligomers. mcK6A1 can be used in research of Alzheimer's disease and other amyloid-related diseases .

HY-P2434

AP102	Somatostatin Receptor	Neurological Disease Metabolic Disease Cancer
AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC₅₀: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .

HY-P5362A

NODAGA-LM3 TFA	Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor	Cancer
NODAGA-LM3 TFA can be labeled by ⁶⁸Ga for PET imaging. ⁶⁸Ga-NODAGA-LM3 TFA is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas. NODAGA-LM3 TFA can be labeled with [68Ga] for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .

HY-P5362

NODAGA-LM3	Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor	Cancer
NODAGA-LM3 can be labeled by ⁶⁸Ga for PET imaging. ⁶⁸Ga-NODAGA-LM3 is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas. NODAGA-LM3 can be labeled with [68Ga] for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .

HY-105168

TAK 044	Endothelin Receptor	Cardiovascular Disease
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .

HY-P4070

Insulin icodec	Peptides	Metabolic Disease
Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec can be used for the research of type 2 diabetes .

HY-105055

Didemnin B	Peptides	Cancer
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0384

Homovanillic acid Vanilacetic acid	Structural Classification Monophenols Immune System Disorder Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Phenols Endocrine diseases Metabolic Disease Nervous System Disorder Endogenous metabolite Disease Research Fields	Drug Metabolite Endogenous Metabolite Autophagy
Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384R

Homovanillic acid (Standard) Vanilacetic acid (Standard)	Structural Classification Monophenols Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Phenols Endocrine diseases Nervous System Disorder Endogenous metabolite	Reference Standards Autophagy Endogenous Metabolite Drug Metabolite
Homovanillic acid (Standard) (Vanilacetic acid (Standard)) is the analytical standard of Homovanillic acid (HY-N0384). This product is intended for research and analytical applications. Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-W011727

Pyridoxal 5'-phosphate hydrate 2 Publications Verification Pyridoxal phosphate hydrate	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Amyloid-β ERK
Pyridoxal 5'-phosphate hydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate hydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .

HY-W011727A

Pyridoxal 5'-phosphate monohydrate 2 Publications Verification Pyridoxal phosphate monohydrate	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite Amyloid-β ERK
Pyridoxal 5'-phosphate monohydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate monohydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′‐phosphate (PMP) .

HY-105055

Didemnin B	Structural Classification Natural Products Animals Classification of Application Fields Marine natural products Source classification Other marine organisms Disease Research Fields Cancer	Others
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .

HY-W011727AR

Pyridoxal 5'-?phosphate monohydrate (Standard) Pyridoxal phosphate monohydrate (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite Amyloid-β ERK
Pyridoxal 5'-phosphate (monohydrate) (Standard) is the analytical standard of Pyridoxal 5'-phosphate (monohydrate). This product is intended for research and analytical applications. Pyridoxal 5'-phosphate monohydrate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate monohydrate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .

HY-N7512

Asimilobine	Infection Alkaloids Structural Classification Monophenols Classification of Application Fields Source classification Phenols Nelumbo nucifera Gaertn. Plants Isoquinoline Alkaloids Nymphaeaceae Disease Research Fields	Dopamine Receptor 5-HT Receptor Parasite
Asimilobine is an aporphine isoquinoline alkaloid isolated from plant species of Magnolia obobata Thun. Asimilobine is a dopamine biosynthesis inhibitor and a serotonergic receptor antagonist. Asimilobine shows an antimalarial and anti-cancer activity .

Species:	Human (6) Mouse (2)
Tag:	His (7) Tag Free (1) Strep (1) MBP (1) Flag (1)
Source:	HEK293 (2) sf9 insect cells (1) Sf9 insect cells (2) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P701909

	hDDC Protein, Human DDC; Aromatic-L-amino-acid decarboxylase; AADC; DOPA decarboxylase; DDC	Human	E. coli
	hDDC protein plays a central role in neurotransmitter synthesis by catalyzing the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to produce dopamine and L-5-hydroxytryptophan to produce serotonin. hDDC Protein, Human is the recombinant human-derived hDDC protein, expressed by E. coli , with tag free.

HY-P74204

	DDC Protein, Mouse (sf9, His) Aromatic-L-amino-acid decarboxylase; AADC; DOPA decarboxylase; DDC	Mouse	Sf9 insect cells
	The DDC protein plays a key role in neurotransmitter synthesis as it catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to produce dopamine and L-5-hydroxytryptophan to produce serotonin. These enzymatic reactions represent key steps in neurotransmitter biosynthesis and are essential for the normal functioning of the central nervous system. DDC Protein, Mouse (sf9, His) is the recombinant mouse-derived DDC protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P75514

	Aminoacylase-1 Protein, Mouse (HEK293, His) aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; Acy1	Mouse	HEK293
	The Aminoacylase-1 protein plays an important role in cellular processes as it catalyzes the hydrolysis of N-acetylated amino acids, promoting the conversion of these compounds into acetate and free amino acids. This enzymatic activity highlights the importance of Aminoacylase-1 in the metabolic pathways responsible for the breakdown of N-acetylated amino acids, helping to release essential amino acids and acetate as by-products. Aminoacylase-1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Aminoacylase-1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P701910

	hDDC Protein, Human (His, StrepⅡ) DDC; Aromatic-L-amino-acid decarboxylase; AADC; DOPA decarboxylase; DDC	Human	E. coli
	hDDC protein plays a central role in neurotransmitter synthesis by catalyzing the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to produce dopamine and L-5-hydroxytryptophan to produce serotonin. hDDC Protein, Human (His, Strep) is the recombinant human-derived hDDC protein, expressed by E. coli , with N-Strep, N-6*His labeled tag.

HY-P704655

	hDDC Protein, Human (Sf9, His) DDC; Aromatic-L-amino-acid decarboxylase; AADC; DOPA decarboxylase; DDC	Human	sf9 insect cells
	hDDC protein plays a central role in neurotransmitter synthesis by catalyzing the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to produce dopamine and L-5-hydroxytryptophan to produce serotonin. hDDC Protein, Human (Sf9, His) is the recombinant human-derived hDDC protein, expressed by sf9 insect cells, with C-His labeled tag.

HY-P7457

	ACY3 Protein, Human (His) rHuACY3, His; N-acyl-aromatic-L-amino acid amidohydrolase; ACY-3	Human	E. coli
	ACY3 Protein, Human (His) is human recombinant ACY3 with a N-terminal His tag. ACY3 Protein, Human (His) plays an important role in deacetylating mercapturic acids in kidney proximal tubules.

HY-P75576

	Aminoacylase-1 Protein, Human (sf9, His) aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; Acy1	Human	Sf9 insect cells
	The Aminoacylase-1 protein plays a crucial role in catalyzing the hydrolysis of N-acetylated amino acids, leading to the production of acetate and free amino acids. Aminoacylase-1 Protein, Human (sf9, His) is the recombinant human-derived Aminoacylase-1 protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P703256

	SLC7A7-SLC3A2 Protein, Human (HEK293, His, MBP, Flag) Y+L amino acid transporter 1; Monocyte amino acid permease 2; MOP-2; Solute carrier family 7 member 7; y(+)L-type amino acid transporter 1; Y+LAT1; y+LAT-1; SLC7A7; Homo sapiens; Human; MOP-2	Human	HEK293

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Cat. No.	Product Name	Chemical Structure

HY-N0384S2

Homovanillic acid-d5
Homovanillic acid-d₅ (Vanilacetic acid-d₅) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S

Homovanillic acid-d3
Homovanillic acid-d₃ (Vanilacetic acid-d₃) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S3

Homovanillic acid-13C6,18O
Homovanillic acid- ¹³C₆, ¹⁸O (Vanilacetic acid- ¹³C₆, ¹⁸O) is the ¹³C- and ¹⁸O-labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-W011727S

Pyridoxal Phosphate-d3

Pyridoxal Phosphate-d₃ is the deuterium labeled Pyridoxal 5'-phosphate. Pyridoxal 5'-phosphate, the active form of vitamin B6, is an essential cofactor for multiple enzymes, including aromatic l-amino acid decarboxylase that catalyzes the final stage in the production of the neurotransmitters dopamine and serotonin. Pyridoxal 5'-phosphate is the most important coenzyme variant in the process of vitamin B6 intracellular phosphorylation and is interconvertible with other variants, including pyridoxine 5′‐phosphate (PNP) and pyridoxamine 5′-phosphate (PMP) .

HY-W777477

Homovanillic Acid-13C6
Homovanillic Acid- ¹³C₆ (Vanilacetic acid- ¹³C₆) is the ¹³C-labeled Homovanillic acid (HY-N0384). Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.

HY-N0384S1

Homovanillic acid-d2
Homovanillic acid-d₂ (Vanilacetic acid-d₂) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S4

Homovanillic acid-d3-1
Homovanillic acid-d₃-1 (Vanilacetic acid-d₃-1) is deuterated labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-N0384S5

Homovanillic acid-13C,d3
Homovanillic acid- ¹³C,d₃ (Vanilacetic acid- ¹³C,d₃) is ¹³C and deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency .

HY-B0404AS

Benserazide-d3 hydrochloride

Benserazide-d₃ (hydrochloride) is the deuterium labeled Benserazide hydrochloride (HY-B0404A). Benserazide hydrochloride (Serazide) is an aromatic L-amino acid decarboxylase (AADC) and L-DOPA decarboxylase inhibitor. Benserazide hydrochloride is also a PKM2 inhibitor. Benserazide hydrochloride directly binds to and blocks PKM2 enzyme activity, leading to inhibition of aerobic glycolysis concurrent up-regulation of OXPHOS. Benserazide hydrochloride can be used for the study of Parkinson's disease and melanoma .

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HY-P82683

	DOPA Decarboxylase Antibody (YA2428) AADC; Aromatic L amino Acid Decarboxylase; DDC; DOPA decarboxylase (aromatic L-amino acid decarboxylase); DOPA decarboxylase	WB	Human, Mouse, Rat
	DOPA Decarboxylase Antibody (YA2428) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DOPA Decarboxylase.

HY-P81480

	IL-4I1/LAO Antibody (YA1225) IL4I1; FIG1 ; UNQ636/PRO1265 ; L-amino-acid oxidase ; Interleukin-4-induced protein 1; hIL4I1 ; Protein Fig-1 ; LAAO; LAO	IHC-P	Human
	IL-4I1/LAO Antibody (YA1225) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-4I1/LAO.

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Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

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