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Results for "

L-PGDS

" in MedChemExpress (MCE) Product Catalog:

By Targets:	PGE synthase (5) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Inflammation/Immunology (4)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (2)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-13988

AT-56	PGE synthase	Inflammation/Immunology
AT-56 is a potent, selective and orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS), with an IC₅₀ of 95 μM and K_i of 75 μM. AT-56 could selectively suppress the drowsiness or pain reaction mediated by L-PGDS-catalyzed PGD₂ .

HY-10439

HPGDS inhibitor 1	PGE synthase	Inflammation/Immunology
HPGDS inhibitor 1 is a potent, selective and orally active Hematopoietic Prostaglandin D Synthase (HPGDS) inhibitor with an IC₅₀s of 0.6 nM and 32 nM in enzyme and cellular assays, respectively. HPGDS inhibitor 1 does not inhibit human L-PGDS, mPGES, COX-1, COX-2, or 5-LOX .

HY-108259

HQL-79	PGE synthase	Inflammation/Immunology
HQL-79, a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD₂, and acts as an anti-allergic agent, with a K_d of 0.8 μM and an IC₅₀ of 6 μM. Shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS .

HY-13988R

AT-56 (Standard)	PGE synthase	Inflammation/Immunology
AT-56 (Standard) is the analytical standard of AT-56. This product is intended for research and analytical applications. AT-56 is a potent, selective and orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS), with an IC50 of 95 μM and Ki of 75 μM. AT-56 could selectively suppress the drowsiness or pain reaction mediated by L-PGDS-catalyzed PGD2 .

HY-E70559

Prostaglandin D synthase	PGE synthase	Cardiovascular Disease Cancer
Prostaglandin D synthase is a biomarker for meningioma cells and coronary artery disease. Lipocalin-type Prostaglandin D synthase (L-PGDS) is present in the atherosclerotic plaque of the human coronary artery and can be detectable in human serum .

HY-RS11374

PTGDS Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PTGDS Human Pre-designed siRNA Set A contains three designed siRNAs for PTGDS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PTGDS Human Pre-designed siRNA Set A PTGDS Human Pre-designed siRNA Set A

HY-RS18401

Ptgds Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ptgds Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptgds gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ptgds Mouse Pre-designed siRNA Set A Ptgds Mouse Pre-designed siRNA Set A

Species:	Rat (1) Mouse (1)
Tag:	His (2) Strep (1)
Source:	HEK293 (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P73709

	PGD2 Synthase/PTGDS Protein, Rat (HEK293, His) Prostaglandin-H2 D-isomerase; L-PGDS; PGDS2; PTGDS	Rat	HEK293
	The PGD2 synthase/PTGDS protein converts PGH2 to PGD2, which regulates smooth muscle and inhibits platelet aggregation.It affects central nervous system functions including sedation, NREM sleep, and potential anti-apoptotic effects on oligodendrocytes.PGD2 Synthase/PTGDS Protein, Rat (HEK293, His) is the recombinant rat-derived PGD2 Synthase/PTGDS protein, expressed by HEK293 , with C-His, C-6*His labeled tag.

HY-P73710

	PGD2 Synthase/PTGDS Protein, Mouse (HEK293, His) Prostaglandin-H2 D-isomerase; L-PGDS; PGDS2; PTGDS	Mouse	HEK293
	PGD2 Synthase/PTGDS Protein, an enzyme, is involved in the synthesis of prostaglandin D2 (PGD2). Dysregulation of PGD2 Synthase/PTGDS Protein has been linked to allergic diseases and inflammation. Targeting PGD2 Synthase/PTGDS Protein may provide potential therapeutic interventions in these conditions by modulating PGD2 levels, reducing allergic responses, and managing inflammation-related disorders. PGD2 Synthase/PTGDS Protein, Mouse (HEK293, His) is the recombinant mouse-derived PGD2 Synthase/PTGDS protein, expressed by HEK293 , with C-His labeled tag.

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HY-P81994

	Prostaglandin D Synthase Antibody (YA1739) PDS; PGD2; PGDS; LPGDS; PGDS2; L-PGDS	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	Prostaglandin D Synthase Antibody (YA1739) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1739), targeting Prostaglandin D Synthase, with a predicted molecular weight of 21 kDa (observed band size: 26 kDa). Prostaglandin D Synthase Antibody (YA1739) can be used for WB, IHC-F, IHC-P, ICC/IF experiment in human, mouse, rat background.

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Cat. No.	Product Name		Classification

HY-RS11374

PTGDS Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PTGDS Human Pre-designed siRNA Set A contains three designed siRNAs for PTGDS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS18401

Ptgds Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Ptgds Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptgds gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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