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Results for "

KV4.2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Potassium Channel (10) Small Interfering RNA (siRNA) (3) Sodium Channel (2)
By Research Areas:	Cardiovascular Disease (1) Neurological Disease (10)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Peptides

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P5785A

Heteropodatoxin-2 TFA	Potassium Channel	Neurological Disease
Heteropodatoxin-2 (TFA), a peptides of 30-amino acid, is a heteropodatoxin. Heteropodatoxin-2 blocks Kv4.2 current expressed in Xenopus laevis oocytes in a voltage-dependent manner, with less block at more positive potentials .

HY-108588

NS5806	Potassium Channel	Cardiovascular Disease
NS5806, a potent potassium current activator, increases *K_V4.3/KChIP2* peak current amplitudes with an EC₅₀ of 5.3 μM. NS5806 slows K_V4.3 and K_V4.2 current dacay in channel complexes containing KChIP2 .

HY-108574

CP 339818 hydrochloride	Potassium Channel	Neurological Disease
CP 339818 hydrochloride is a nonpeptide and selective Kv1.3 (IC₅₀ value of ~200 nM) blocker. CP 339818 hydrochloride also inhibits Kv1.4 channels. CP 339818 hydrochloride is a significantly less potent blocker of Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2. CP 339818 hydrochloride potently blocks the C-type inactivated conformation of Kv1.3 and suppresses T cell activation .

HY-P5785

Heteropodatoxin-2	Potassium Channel	Neurological Disease
Heteropodatoxin-2, a peptides of 30-amino acid, is a heteropodatoxin. Heteropodatoxin-2 blocks Kv4.2 current expressed in Xenopus laevis oocytes in a voltage-dependent manner, with less block at more positive potentials .

HY-P5786

Heteropodatoxin-1	Potassium Channel Sodium Channel	Neurological Disease
Heteropodatoxin-1 (HpTx1), a spider peptide toxin, is a Kv4.2 current inhibitor. Heteropodatoxin-1 also inhibits Nav1.7 and activates Nav1.9 but does not affect Nav1.8 .

HY-P5770

Jingzhaotoxin-V	Sodium Channel	Neurological Disease
Jingzhaotoxin-V, a 29-residue polypeptide, is derived from the venom of the spider Chilobrachys jingzhao. Jingzhaotoxin-V inhibits tetrodotoxin-resistant and tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons with IC₅₀ values of 27.6 nM and 30.2 nM, respectively. Jingzhaotoxin-V also inhibits Kv4.2 potassium currents expressed in Xenpus Laevis oocytes (IC₅₀ of 604.2 nM) .

HY-P2786A

Phrixotoxin 2	Potassium Channel	Neurological Disease
Phrixotoxin 2 is a highly selective *KV_4.2* and *KV_4.3*-channels blocker .

HY-P5157

BmP02	Potassium Channel	Neurological Disease
BmP02 is a selective Kv1.3 channel blocker and a highly-selective *Kv4.2* modulator, which can be isolated from Chinese scorpion (Buthus martensi Karsch) venom. BmP02 also delays the inactivation of Kv4.2 in HEK293T cells, with an EC₅₀ value of ~850 nM. BmP02 inhibits the transient outward potassium currents (Ito) in ventricular muscle cells .

HY-P5873

Jingzhaotoxin-X JZTX-X	Potassium Channel	Neurological Disease
Jingzhaotoxin-X (JZTX-X) is a selective *Kv4.2* and *Kv4.3* potassium channels inhibitor. Jingzhaotoxin-X causes long-lasting mechanical hyperalgesia .

HY-114540

CP-339818	Potassium Channel	Neurological Disease
CP-339818 is a non-peptide drug with potent Kv1.3 channel blocking activity. CP-339818 is able to effectively inhibit the activation of human T cells. By selectively blocking Kv1.3, CP-339818 is of great value in immune system research. The drug inhibits the C-type inactivated state of Kv1.3 channels in a use-dependent manner. CP-339818 has significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels, and only shows some inhibition on the Kv1.4 channel .

HY-P5155

Stromatoxin 1	Potassium Channel	Neurological Disease
Stromatoxin 1 is an inhibitor of Potassium Channel, a peptide which can be isolated from tarantulas. Stromatoxin 1 selectively inhibits K(V)2.1, K(V)2.2, *K(V)4.2*, and K(V)2.1/9.3 channels. K(V)2.1 and K(V)2.2, but not K(V)4.2, channel subunits play a key role in opposing both myogenic and neurogenic urinary bladder smooth muscle (UBSM) contractions in rats .

HY-RS07113

KCND2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
KCND2 Human Pre-designed siRNA Set A contains three designed siRNAs for KCND2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

KCND2 Human Pre-designed siRNA Set A KCND2 Human Pre-designed siRNA Set A

HY-RS21609

Kcnd2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Kcnd2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kcnd2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Kcnd2 Mouse Pre-designed siRNA Set A Kcnd2 Mouse Pre-designed siRNA Set A

HY-RS28127

Kcnd2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Kcnd2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Kcnd2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Kcnd2 Rat Pre-designed siRNA Set A Kcnd2 Rat Pre-designed siRNA Set A

Cat. No.	Product Name	Target	Research Area