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Results for "

KAT7

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

3

Recombinant Proteins

3

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-176244

    Histone Acetyltransferase Cancer
    KI-TOX-A3 is a selective protein-protein interaction (PPI) inhibitor targeting TOX protein (with an IC50 value of 0.51 μM for TOX-KAT7 interaction). KI-TOX-A3 induces proteasomal degradation of TOX, restores KAT7-mediated H3K14 acetylation, reversing CD8 + T cell exhaustion and inhibiting T-cell acute lymphoblastic leukemia (T-ALL) cell proliferation. KI-TOX-A3 is promising for research of hematological tumors (e.g., T-ALL) .
    KI-TOX-A3
  • HY-134901
    WM-3835
    5+ Cited Publications

    Histone Acetyltransferase Apoptosis Cancer
    WM-3835 is a potent and high-specific HBO1 (KAT7 or MYST2) inhibitor and binds directly to the acetyl-CoA binding site of HBO1. WM-3835 activates apoptosis while inhibits osteosarcoma (OS) cell proliferation, migration and invasion. WM-3835 has antitumor activity and potently inhibits pOS-1 xenograft growth in mice .
    WM-3835
  • HY-102058
    WM-1119
    5+ Cited Publications

    Histone Acetyltransferase Cancer
    WM-1119 is a highly potent and selective KAT6A inhibitor, with an IC50 of 0.25 μM for KAT6A in lymphoma cells, the binding KD values of WM-1119 with KAT6A, KAT5 and KAT7 are 2 nM, 2.2 μM, 0.5 μM , respectively .
    WM-1119
  • HY-RS07083

    Small Interfering RNA (siRNA) Histone Acetyltransferase Others

    KAT7 Human Pre-designed siRNA Set A contains three designed siRNAs for KAT7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    KAT7 Human Pre-designed siRNA Set A
    KAT7 Human Pre-designed siRNA Set A
  • HY-RS23353

    Small Interfering RNA (siRNA) Others

    Kat7 Rat Pre-designed siRNA Set A contains three designed siRNAs for Kat7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Kat7 Rat Pre-designed siRNA Set A
    Kat7 Rat Pre-designed siRNA Set A
  • HY-RS16911

    Small Interfering RNA (siRNA) Others

    Kat7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kat7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Kat7 Mouse Pre-designed siRNA Set A
    Kat7 Mouse Pre-designed siRNA Set A
  • HY-177044

    Histone Acetyltransferase Cancer
    KAT6A/KAT7-IN-2 (Example 177) is a KAT6A and KAT7 inhibitor. KAT6A/KAT7-IN-2 has IC50 values of both ≤ 1 nM for KAT6A and KAT7. KAT6A/KAT7-IN-2 can inhibit the acetylation of H3K14 and H3K23. KAT6A/KAT7-IN-2 also inhibits tumor cell proliferation, with an IC50 of ≤ 100 nM for CAMA-1. KAT6A/KAT7-IN-2 can be used in the study of cancer .
    KAT6A/KAT7-IN-2
  • HY-177046

    Histone Acetyltransferase Cancer
    KAT6A/KAT7-IN-4 (Example 230) is a KAT6A and KAT7 inhibitor. KAT6A/KAT7-IN-4 has IC50 values of both ≤ 1 nM for KAT6A and KAT7. KAT6A/KAT7-IN-4 can inhibit the acetylation of H3K14 and H3K23. KAT6A/KAT7-IN-4 also inhibits tumor cell proliferation, with an IC50 of ≤ 100 nM for CAMA-1. KAT6A/KAT7-IN-4 can be used in the study of cancer .
    KAT6A/KAT7-IN-4
  • HY-177043

    Histone Acetyltransferase Cancer
    KAT6A/KAT7-IN-1 (Example 113) is a KAT6A and KAT7 inhibitor. The IC50 of KAT6A/KAT7-IN-1 for KAT6A is > 1 nM but ≤ 10 nM, while the IC50 for KAT7 is ≤ 1 nM. KAT6A/KAT7-IN-1 can inhibit the acetylation of H3K14 and H3K23. KAT6A/KAT7-IN-1 also inhibits tumor cell proliferation, with an IC50 of > 2 μM but ≤ 5 μM for CAMA-1. KAT6A/KAT7-IN-1 can be used in the study of cancer .
    KAT6A/KAT7-IN-1
  • HY-177045

    Histone Acetyltransferase Cancer
    KAT6A/KAT7-IN-3 (Example 191) is a KAT6A and KAT7 inhibitor. The IC50 of KAT6A/KAT7-IN-3 for KAT6A is ≤ 50 nM and > 10 nM, while the IC50 for KAT7 is ≤ 1 nM. KAT6A/KAT7-IN-3 can inhibit the acetylation of H3K14 and H3K23. KAT6A/KAT7-IN-3 also inhibits tumor cell proliferation, with an IC50 of > 2 μM and ≤ 5 μM for CAMA-1. KAT6A/KAT7-IN-3 can be used in the study of cancer .
    KAT6A/KAT7-IN-3
  • HY-168428

    Histone Acetyltransferase Apoptosis Cancer
    CHI-KAT8i5 is a selective and orally active KAT8 inhibitor with a KD value of 19.72 μM. CHI-KAT8i5 does not bind to other proteins in HAT family (KAT2A, KAT2B, KAT5, and KAT7). CHI-KAT8i5 induces cancer cell apoptosis. CHI-KAT8i5 suppresses esophageal squamous cell carcinoma (ESCC) growth through targeting KAT8/c-Myc signaling pathway .
    CHI-KAT8i5

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