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JQ-1 (carboxylic acid)-NH-C2-NH-COOH

" in MedChemExpress (MCE) Product Catalog:

44

Inhibitors & Agonists

3

Fluorescent Dye

23

Biochemical Assay Reagents

6

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1040
    Cy5.5-COOH

    Cyanine 5.5 carboxylic acid

    		 Fluorescent Dye Others
    Cy5.5-COOH (Cyanine 5.5 carboxylic acid) is a fluorescent dye that emits fluorescence at 710 nm upon excitation at 650 nm. Cy5.5-COOH possesses excellent spectral properties, including a narrow absorption spectrum, high sensitivity, and stability. Cy5.5-COOH can be used for bioimaging and disease diagnosis .
    Cy5.5-COOH
  • HY-133053
    HO-PEG8-CH2CH2COOH

    Hydroxy-PEG8-acid

    		 Biochemical Assay Reagents Others
    HO-PEG8-CH2CH2COOH (Hydroxy-PEG8-acid) is a PEG derivative containing a hydroxyl group with a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators to form a stable amide bond .
    HO-PEG8-CH2CH2COOH
  • HY-W1048542
    Fmoc-NH-PEG-COOH (MW1000)

    		Biochemical Assay Reagents Others
    Fmoc-NH-PEG-COOH (MW1000) is a PEG product containing two Fmoc-protected amines and a carboxylic acid. Fmoc-NH-PEG-COOH (MW1000) is an important cross-linking agent with PEG chains .
    Fmoc-NH-PEG-COOH (MW1000)
  • HY-W440827
    DOPE-PEG-COOH (MW 2000)
    1 Publications Verification

    		 Liposome Others
    DOPE-PEG-COOH (MW 2000) is a PEG polymer containing unsaturated DOPE phospholipids and carboxylic acids. DOPE-PEG-COOH (MW 2000) can be used to prepare liposomes or other nanoparticles for drug delivery .
    DOPE-PEG-COOH (MW 2000)
  • HY-D2493
    Cyanine7 carboxylic acid

    Cy7 COOH

    		 Fluorescent Dye Others
    Cyanine7 carboxylic acid (Cy7 COOH) is a derivative of Cy7 (HY-D0825) dye. Cyanine7 carboxylic acid contains carboxyl groups, which can condense ammonia to form covalent bonds .
    Cyanine7 carboxylic acid
  • HY-D1040A
    CY5.5-COOH chloride

    Cyanine 5.5 carboxylic acid chloride

    		 Fluorescent Dye Others
    Cy5.5-COOH (Cyanine 5.5 carboxylic acid) chloride is a fluorescent dye that emits fluorescence at 710 nm upon excitation at 650 nm. Cy5.5-COOH chloride possesses excellent spectral properties, including a narrow absorption spectrum, high sensitivity, and stability. Cy5.5-COOH chloride can be used for bioimaging and disease diagnosis .
    CY5.5-COOH chloride
  • HY-169082
    JQ-1 (carboxylic acid)-NH-C2-NH-COOH

    		E3 Ligase Ligand-Linker Conjugates Cancer
    JQ-1 (carboxylic acid)-NH-C2-NH-COOH is a conjugate of E3 ligase ligand and linker (E3 Ligase Ligand-Linker Conjugates), which is composed of JQ-1 carboxylic acid (HY-78695) and the corresponding linker: (2-Aminoethyl)carbamic acid (HY-W398806). JQ-1 (carboxylic acid)-NH-C2-NH-COOH can be used as a Cereblon ligand to recruit CRBN protein and as a key intermediate for the synthesis of complete PROTACs molecules .
    JQ-1 (carboxylic acid)-NH-C2-NH-COOH
  • HY-145991R
    Ribavirin carboxylic acid (Standard)

    		Reference Standards Drug Metabolite Infection
    Ribavirin carboxylic acid (Standard) is the analytical standard of Ribavirin carboxylic acid. This product is intended for research and analytical applications. Ribavirin carboxylic acid (TR-COOH) is a metabolite of Ribavirin (HY-B0434), Ribavirin has strong antiviral activity .
    Ribavirin carboxylic acid (Standard)
  • HY-W835383
    Sulfo Cy5.5-COOH

    		Fluorescent Dye Others
    Sulfo-Cy5.5-COOH is a sulfonated Cy5.5 fluorescent dye containing a sulfonic acid group and a carboxylic acid group. The fluorescence wavelength of Sulfo-Cy5.5-COOH is in the near-infrared region and has strong penetrating power.
    Sulfo Cy5.5-COOH
  • HY-141651
    (S,R,S)-AHPC-C3-COOH

    		E3 Ligase Ligand-Linker Conjugates Cancer
    (S,R,S)-AHPC-C3-COOH (compound 28i) is a carboxylic acid derivative of the VHL E3 ubiquitin ligase ligand-Linker conjugate. (S,R,S)-AHPC-C3-COOH can be used to synthesize PROTACs .
    (S,R,S)-AHPC-C3-COOH
  • HY-145991
    Ribavirin carboxylic acid

    		Drug Metabolite Infection
    Ribavirin carboxylic acid (TR-COOH) is a metabolite of Ribavirin (HY-B0434), Ribavirin has strong antiviral activity .
    Ribavirin carboxylic acid
  • HY-W1048574J
    OHC-PEG-COOH (MW 40000)

    OHC-PEG-carboxyl (MW 40000)

    		 Biochemical Assay Reagents Others
    OHC-PEG-COOH (MW 40000) (OHC-PEG-carboxyl (MW 40000)) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG-COOH (MW 40000) can be used for drug delivery .
    OHC-PEG-COOH (MW 40000)
  • HY-W1048574H
    OHC-PEG-COOH (MW 1000)

    OHC-PEG-carboxyl (MW 1000)

    		 Biochemical Assay Reagents Others
    OHC-PEG-COOH (MW 1000) (OHC-PEG-carboxyl (MW 1000)) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG-COOH (MW 1000) can be used for drug delivery .
    OHC-PEG-COOH (MW 1000)
  • HY-W1048574I
    OHC-PEG-COOH (MW 3400)

    OHC-PEG-carboxyl (MW 3400)

    		 Biochemical Assay Reagents Others
    OHC-PEG-COOH (MW 3400) (OHC-PEG-carboxyl (MW 3400)) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG-COOH (MW 3400) can be used for drug delivery .
    OHC-PEG-COOH (MW 3400)
  • HY-W1048574A
    OHC-PEG-COOH (MW 2000)

    OHC-PEG-carboxyl (MW 2000)

    		 Biochemical Assay Reagents Others
    OHC-PEG-COOH (MW 2000) (OHC-PEG-carboxyl (MW 2000)) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG-COOH (MW 2000) can be used for drug delivery .
    OHC-PEG-COOH (MW 2000)
  • HY-W1048574E
    OHC-PEG-COOH (MW 20000)

    OHC-PEG-carboxyl (MW 20000)

    		 Biochemical Assay Reagents Others
    OHC-PEG-COOH (MW 20000) (OHC-PEG-carboxyl (MW 20000)) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG-COOH (MW 20000) can be used for drug delivery .
    OHC-PEG-COOH (MW 20000)
  • HY-W1048574D
    OHC-PEG-COOH (MW 10000)

    OHC-PEG-carboxyl (MW 10000)

    		 Biochemical Assay Reagents Others
    OHC-PEG-COOH (MW 10000) (OHC-PEG-carboxyl (MW 10000)) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG-COOH (MW 10000) can be used for drug delivery .
    OHC-PEG-COOH (MW 10000)
  • HY-W1048574C
    OHC-PEG-COOH (MW 5000)

    OHC-PEG-carboxyl (MW 5000)

    		 Biochemical Assay Reagents Others
    OHC-PEG-COOH (MW 5000) (OHC-PEG-carboxyl (MW 5000)) is a PEG derivative with a linear heteroterminal bifunctional structure of aldehyde and carboxylic acid groups. OHC-PEG-COOH (MW 5000) can be used for drug delivery .
    OHC-PEG-COOH (MW 5000)
  • HY-131699
    t-Butyl ester-PEG4-CH2COOH

    		Biochemical Assay Reagents Others
    t-Butyl ester-PEG4-CH2COOH is a PEG linker containing a t-butyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl group can be deprotected under acidic conditions.
    t-Butyl ester-PEG4-CH2COOH
  • HY-W403327
    CbzNH-PEG4-CH2COOH

    		Biochemical Assay Reagents Others
    CbzNH-PEG4-CH2COOH is a PEG linker containing an carboxylic acid (CO2H) group and a benzyl (Cbz) protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators (e.g. HATU) forming a stable amide bond. The benzyl protecting group can be removed via hydrogenolysis to form a free amine.
    CbzNH-PEG4-CH2COOH
  • HY-W1048542A
    Fmoc-NH-PEG-COOH (MW 2000)

    		Biochemical Assay Reagents Others
    Fmoc-NH-PEG-COOH (MW 2000) is a linear hetero-bifunctional PEG product with two Fmoc-protected amines and a carboxylic acid at both ends. Fmoc-NH-PEG-COOH (MW 2000) is an important cross-linking agent with PEG chains. The protected amine can be regenerated by mild alkaline conditions .
    Fmoc-NH-PEG-COOH (MW 2000)
  • HY-W1048542D
    Fmoc-NH-PEG-COOH (MW 5000)

    		Biochemical Assay Reagents Others
    Fmoc-NH-PEG-COOH (MW 5000) is a linear hetero-bifunctional PEG product with two Fmoc-protected amines and a carboxylic acid at both ends. Fmoc-NH-PEG-COOH (MW 5000) is an important cross-linking agent with PEG chains. The protected amine can be regenerated by mild alkaline conditions .
    Fmoc-NH-PEG-COOH (MW 5000)
  • HY-W1048542I
    Fmoc-NH-PEG-COOH (MW 40000)

    		Biochemical Assay Reagents Others
    Fmoc-NH-PEG-COOH (MW 40000) is a linear hetero-bifunctional PEG product with two Fmoc-protected amines and a carboxylic acid at both ends. Fmoc-NH-PEG-COOH (MW 40000) is an important cross-linking agent with PEG chains. The protected amine can be regenerated by mild alkaline conditions .
    Fmoc-NH-PEG-COOH (MW 40000)
  • HY-W1048542E
    Fmoc-NH-PEG-COOH (MW 10000)

    		Biochemical Assay Reagents Others
    Fmoc-NH-PEG-COOH (MW 10000) is a linear hetero-bifunctional PEG product with two Fmoc-protected amines and a carboxylic acid at both ends. Fmoc-NH-PEG-COOH (MW 10000) is an important cross-linking agent with PEG chains. The protected amine can be regenerated by mild alkaline conditions .
    Fmoc-NH-PEG-COOH (MW 10000)
  • HY-W1048542C
    Fmoc-NH-PEG-COOH (MW 3400)

    		Biochemical Assay Reagents Others
    Fmoc-NH-PEG-COOH (MW 3400) is a linear hetero-bifunctional PEG product with two Fmoc-protected amines and a carboxylic acid at both ends. Fmoc-NH-PEG-COOH (MW 3400) is an important cross-linking agent with PEG chains. The protected amine can be regenerated by mild alkaline conditions .
    Fmoc-NH-PEG-COOH (MW 3400)
  • HY-W1048542H
    Fmoc-NH-PEG-COOH (MW 20000)

    		Biochemical Assay Reagents Others
    Fmoc-NH-PEG-COOH (MW 20000) is a linear hetero-bifunctional PEG product with two Fmoc-protected amines and a carboxylic acid at both ends. Fmoc-NH-PEG-COOH (MW 20000) is an important cross-linking agent with PEG chains. The protected amine can be regenerated by mild alkaline conditions .
    Fmoc-NH-PEG-COOH (MW 20000)
  • HY-174906
    Bis-PEG-COOH (MW 1000)

    		Biochemical Assay Reagents Others
    Bis-PEG-COOH (MW 1000) is a disubstituted PEG derivative with the same functional group. The carboxylic acid group in Bis-PEG-COOH (MW 1000) can react with other compounds containing amino, hydroxyl and other functional groups to form stable chemical bonds, which can be used for drug delivery .
    Bis-PEG-COOH (MW 1000)
  • HY-W591461
    DSPE-PEG-COOH, MW 2000

    		Liposome Cancer
    DSPE-PEG-COOH, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal carboxylic acid can react with primary amine groups to form a stable amide bond.
    DSPE-PEG-COOH, MW 2000
  • HY-176206
    Biotin-PEG-COOH (MW 1000)

    		Biochemical Assay Reagents Others
    Biotin-PEG-COOH (MW 1000) is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG-COOH (MW 1000) can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
    Biotin-PEG-COOH (MW 1000)
  • HY-176206B
    Biotin-PEG-COOH (MW 3400)

    		Biochemical Assay Reagents Others
    Biotin-PEG-COOH (MW 3400) is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG-COOH (MW 3400) can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
    Biotin-PEG-COOH (MW 3400)
  • HY-176206E
    Biotin-PEG-COOH (MW 20000)

    		Biochemical Assay Reagents Others
    Biotin-PEG-COOH (MW 20000) is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG-COOH (MW 20000) can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
    Biotin-PEG-COOH (MW 20000)
  • HY-176206D
    Biotin-PEG-COOH (MW 10000)

    		Biochemical Assay Reagents Others
    Biotin-PEG-COOH (MW 10000) is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG-COOH (MW 10000) can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
    Biotin-PEG-COOH (MW 10000)
  • HY-176206H
    Biotin-PEG-COOH (MW 40000)

    		Biochemical Assay Reagents Others
    Biotin-PEG-COOH (MW 40000) is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG-COOH (MW 401000) can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
    Biotin-PEG-COOH (MW 40000)
  • HY-176206A
    Biotin-PEG-COOH (MW 2000)

    		Biochemical Assay Reagents Others
    Biotin-PEG-COOH (MW 2000) is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG-COOH (MW 2000) can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
    Biotin-PEG-COOH (MW 2000)
  • HY-176206C
    Biotin-PEG-COOH (MW 5000)

    		Biochemical Assay Reagents Others
    Biotin-PEG-COOH (MW 5000) is a linear heterobifunctional PEG compound with biotin and carboxylic acid functional groups. Biotin can bind to avidin and streptavidin with high specificity and affinity. Biotin-PEG-COOH (MW 5000) can be used to biotin-label antibodies, proteins and other macromolecules containing primary amines in the presence of a condensing agent .
    Biotin-PEG-COOH (MW 5000)
  • HY-140015A
    (S,E)-TCO2-PEG3-acid

    		PROTAC Linkers Cancer
    (S)-TCO-PEG3-acid is a click chemistry PEG linker with a terminal carboxylic acid(COOH) group. The terminal carboxylic acid is reactive with primary amine groups to form a stable amide bond. (S)-TCO-PEG3-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
    (S,E)-TCO2-PEG3-acid
  • HY-115435
    1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium

    DMPS-Na; Dimyristoyl phosphatidylserine sodium

    		 Liposome Cancer
    1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium is an anionic phospholipid with myristic acid tails (14:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of liposome.
    1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium
  • HY-141161A
    (S,E)-TCO2-PEG8-acid

    		PROTAC Linkers Cancer
    (S)-TCO-PEG8-acid is a click chemistry PEG linker with a terminal carboxylic acid(COOH) group. The terminal carboxylic acid is reactive with primary amine groups to form a stable amide bond. (S)-TCO-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. (S)-TCO-PEG8-acid is longer than (S)-TCO-PEG3-acid .
    (S,E)-TCO2-PEG8-acid
  • HY-W440986
    Distearoylphosphatidylserine sodium

    DSPS sodium

    		 Liposome Others
    Distearoylphosphatidylserine sodium is an anionic phospholipid with stearic acid tails (18:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.
    Distearoylphosphatidylserine sodium
  • HY-W440985
    DLPS

    1,2-dilauroyl-sn-glycero-3-phospho-L-serine

    		 Liposome Cancer
    DLPS is an anionic phospholipid with lauric acid tails (12:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls.
    DLPS
  • HY-W800667
    Hydroxy-PEG4-acid sodium

    		Biochemical Assay Reagents Others
    Hydroxy-PEG4-acid sodium is a PEG linker containing a hydroxyl group with a terminal carboxylic acid (as sodium salt form). The free acid form is not stable due to the reaction of OH with PEG-COOH group to form polymer. The sodium salt form is stable for storage and shipping. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
    Hydroxy-PEG4-acid sodium
  • HY-W714524
    1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine sodium

    1,2-POPS; 1,2-POPS; 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium; 1-Hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine sodium salt

    		 Liposome Metabolic Disease
    2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-L-serine sodium is an anionic phospholipid with oleic acid (18:1) and palmitic acid (16:0) tails containing a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposomes, and artificial membranes.
    1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine sodium
  • HY-116655A
    Hydroxy-PEG1-acid sodium salt

    		Biochemical Assay Reagents Others
    Hydroxy-PEG1-acid sodium is a PEG linker containing a hydroxyl group with a terminal carboxylic acid (as sodium salt form). The free acid form is not stable due to the reaction of OH with PEG-COOH group to form polymer. The sodium salt form is stable for storage and shipping. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
    Hydroxy-PEG1-acid sodium salt
  • HY-W440955
    Stearic acid-PEG-CH2CO2H (MW 3400)

    		Biochemical Assay Reagents Others
    Stearic acid-PEG-CH2CO2H, MW 3400 is a lipophilic thiol-reactive PEG polymer. The stearic acid can be used to encapsulate hydrophobic therapeutic agents while the PEG chain increases overall water solubility and biocompatibilty. Reaction between carboxylic acid (-COOH) and amine (-NH2) vai condensation in the presence of activator, such as HATU or EDC, generates a stable amide linkage. Reagent grade, for research use only.
    Stearic acid-PEG-CH2CO2H (MW 3400)

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