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Results for "

Ivermectin

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

4

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15310
    Ivermectin
    Maximum Cited Publications
    41 Publications Verification

    MK-933; CD-5024; K-237

    Flavivirus Dengue Virus Parasite HIV Mitophagy HSV SARS-CoV Antibiotic Autophagy Bacterial Infection Cancer
    Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X4 and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import . Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .
    Ivermectin
  • HY-126937
    Ivermectin B1a
    1 Publications Verification

    Parasite SARS-CoV Infection
    Ivermectin B1a, a derivative of Avermectin B1a (HY-15308), is a main component of Ivermectin (HY-15310) . Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .
    Ivermectin B1a
  • HY-W654244

    Isotope-Labeled Compounds Others
    Ivermectin-d2 is deuterium labeled Ivermectin .
    Ivermectin-d2
  • HY-125729

    Parasite SARS-CoV Infection
    Ivermectin B1b is the minor component of Ivermectin. Ivermectin, a potent anti-parasitic agent, inhibits the replication of SARS-CoV-2 in cell culture .
    Ivermectin B1b
  • HY-137252

    Ivermectin Impurity G

    Parasite Infection
    22,23-Dihydroavermectin B1a aglycon is an acid degradation product produced by hydrolysis of the disaccharide unit of ivermectin. It can inhibit nematode larval development, but does not cause paralytic activity.
    22,23-Dihydroavermectin B1a aglycon
  • HY-147002

    Parasite SARS-CoV Others
    7-O-Methyl Ivermectin B1a is an analogue of Ivermectin B1a (HY-126937).
    7-O-Methyl Ivermectin B1a
  • HY-120696

    ML368

    Cytochrome P450 Parasite Infection Cancer
    SR9186 (ML368) is a selective CYP3A4 inhibitor with IC50 values of 9, 4, and 38 nM for Midazolam → 1'-hydroxymidazolam, Testosterone → 6β-hydroxytestosterone, and Vincristine → Vincristine M1, respectively. SR-9186 inhibits the development of hepatic-stage P. falciparum and blocks ivermectin metabolism. SR-9186 can be used in breast cancer research .
    SR9186
  • HY-123686

    Parasite Infection
    Ivermectin B1a monosaccharide is a modified Ivermectin B1a (HY-126937). Ivermectin B1a monosaccharide is an antiparasite agent with a minimum concentration for full activity in Haemonchus contortus larval development of 0.001 μg/mL .
    Ivermectin B1a monosaccharide
  • HY-W765152

    22,23-Dihydro avermectin B1a; epi-Dihydro avermectin B1a

    Parasite Infection
    epi-Ivermectin B1a is a key related substance of Ivermectin (HY-15310), primarily existing as a process-related impurity or potential degradation product in ivermectin-based antiparasitic formulations. epi-Ivermectin B1a can be used for the study of internal/external parasites in cattle .
    epi-Ivermectin B1a
  • HY-130484

    Parasite Infection
    2,3-Dehydro-3,4-dihydro ivermectin is an analog of ivermectin (HY-15310) and an anthelmintic. 2,3-Dehydro-3,4-dihydro ivermectin has activity against L. amazonensis promastigotes and amastigotes (IC50s=13.8 and 3.6 µM, respectively) without inducing cytotoxicity to macrophages (IC50= 65.5 µM).
    2,3-Dehydro-3,4-dihydro ivermectin
  • HY-131965

    Drug Intermediate Others
    Imidacloprid impurity 1 (IMP-2) is the impurity found during the synthesis of Ivermectin (HY-15310) .
    Imidacloprid impurity 1
  • HY-17035
    Doramectin
    5 Publications Verification

    Parasite Antibiotic Bacterial Infection
    Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model .
    Doramectin
  • HY-17035R

    Reference Standards Parasite Antibiotic Bacterial Infection
    Doramectin (Standard) is the analytical standard of Doramectin. This product is intended for research and analytical applications. Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model .
    Doramectin (Standard)

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