2. Search Result
Search Result
Results for "

Intermediate of Exatecan

" in MedChemExpress (MCE) Product Catalog:

28

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-42487
    Exatecan Intermediate 1

    		ADC Payload Topoisomerase Cancer
    Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631). Exatecan is a DNA topoisomerase I inhibitor with anticancer effects .
    Exatecan Intermediate 1
  • HY-45171S
    Exatecan intermediate 12-d5

    		Isotope-Labeled Compounds Cancer
    Exatecan intermediate 12-d5 is the deuterium labeled Exatecan intermediate 12 (HY-45171). Exatecan intermediate 12 is an intermediate for the synthesis of ADC toxin Exatecan (HY-13631) and can be used to prepare ADC compounds.
    Exatecan intermediate 12-d5
  • HY-42487B
    (R)-Exatecan Intermediate 1

    		ADC Payload Topoisomerase Cancer
    (R)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1 (HY-42487). Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631), a camptothecin-based anticancer agent. Exatecan inhibits tumor growth by interfering with the proliferation and division of tumor cells by interacting with DNA. Exatecan is primarily used in research into a variety of cancers including ovarian, lung and breast cancer .
    (R)-Exatecan Intermediate 1
  • HY-42487A
    (rac)-Exatecan Intermediate 1

    		ADC Payload Topoisomerase Cancer
    (rac)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1 (HY-42487). Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631), a camptothecin-based anticancer agent. Exatecan inhibits tumor growth by interfering with the proliferation and division of tumor cells by interacting with DNA. Exatecan is primarily used in research into a variety of cancers including ovarian, lung and breast cancer .
    (rac)-Exatecan Intermediate 1
  • HY-42487S
    Exatecan Intermediate 1-d5

    		Isotope-Labeled Compounds ADC Payload Topoisomerase Others
    Exatecan Intermediate 1-d5 is the deuterium labeled Exatecan Intermediate 1 .
    Exatecan Intermediate 1-d5
  • HY-44369
    Exatecan Intermediate 6

    		ADC Payload Topoisomerase Cancer
    Exatecan Intermediate 6 is the intermediate of Exatecan (HY-13631) And Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) that can be used in cancer research. Exatecan Intermediate 6 can be used to synthesize Antibody-Drug Conjugates (ADCs).
    Exatecan Intermediate 6
  • HY-43564
    Exatecan Intermediate 5

    		ADC Payload Topoisomerase Cancer
    Exatecan Intermediate 5 is the intermediate of Exatecan (HY-13631) And Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) that can be used in cancer research. Exatecan Intermediate 5 can be used to synthesize Antibody-Drug Conjugates (ADCs).
    Exatecan Intermediate 5
  • HY-46081
    Exatecan Intermediate 3

    		ADC Payload Topoisomerase Cancer
    Exatecan Intermediate 3 is the intermediate of Exatecan (HY-13631) And Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) that can be used in cancer research. Exatecan Intermediate 3 can be used to synthesize Antibody-Drug Conjugates (ADCs).
    Exatecan Intermediate 3
  • HY-45157
    Exatecan Intermediate 7

    		ADC Payload Topoisomerase Cancer
    Exatecan Intermediate 7 is the intermediate of Exatecan (HY-13631) And Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) that can be used in cancer research. Exatecan Intermediate 7 can be used to synthesize Antibody-Drug Conjugates (ADCs).
    Exatecan Intermediate 7
  • HY-42487R
    Exatecan Intermediate 1 (Standard)

    		ADC Payload Topoisomerase Cancer
    Exatecan Intermediate 1 (Standard) is the analytical standard of Exatecan Intermediate 1. This product is intended for research and analytical applications. Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631). Exatecan is a DNA topoisomerase I inhibitor with anticancer effects .
    Exatecan Intermediate 1 (Standard)
  • HY-45169
    Exatecan intermediate 13

    		Drug Intermediate Others
    Exatecan intermediate 13 is an impurity of Exatecan (HY-13631).
    Exatecan intermediate 13
  • HY-43565B
    Exatecan intermediate 10

    		ADC Payload Topoisomerase Cancer
    Exatecan intermediate 10 is an intermediate in the synthesis of Exatecan (HY-13631).Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 of 2 .2 μM (0 .975 μg/mL) for use in cancer research .
    Exatecan intermediate 10
  • HY-45171
    Exatecan intermediate 12

    		ADC Payload Cancer
    Exatecan intermediate 12 is an intermediate for the synthesis of ADC toxin Exatecan (HY-13631) and can be used to prepare ADC compounds .
    Exatecan intermediate 12
  • HY-W021377
    Exatecan Intermediate 2

    		ADC Payload Drug Intermediate Cancer
    Exatecan Intermediate 2 (Compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
    Exatecan Intermediate 2
  • HY-W021377C
    Exatecan Intermediate 4 dihydrochloride

    		ADC Payload Drug Intermediate Cancer
    Exatecan Intermediate 4 dihydrochloride (Compound 14f) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
    Exatecan Intermediate 4 dihydrochloride
  • HY-W021377A
    Exatecan Intermediate 2 hydrochloride

    		ADC Payload Drug Intermediate Cancer
    Exatecan Intermediate 2 hydrochloride (Compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
    Exatecan Intermediate 2 hydrochloride
  • HY-W021377B
    Exatecan Intermediate 4

    		ADC Payload Drug Intermediate Cancer
    Exatecan Intermediate 4 (Compound 14f) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
    Exatecan Intermediate 4
  • HY-49861
    Exatecan intermediate 11

    		ADC Payload Topoisomerase Cancer
    Exatecan intermediate 11 is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM) .
    Exatecan intermediate 11
  • HY-400316
    Exatecan intermediate 8

    		ADC Payload Topoisomerase Cancer
    Exatecan intermediate 8 is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM) .
    Exatecan intermediate 8
  • HY-43565
    Exatecan intermediate 9

    		ADC Payload Topoisomerase Cancer
    Exatecan intermediate 9 is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM) .
    Exatecan intermediate 9
  • HY-153600
    GGFG-amide-glycol-amide-Exatecan

    		Drug-Linker Conjugates for ADC Topoisomerase Cancer
    GGFG-amide-glycol-amide-Exatecan (Intermediate 2) is an Exatecan (HY-13631) derivative and can be used in the synthesis of antibody-drug conjugates (ADCs) .
    GGFG-amide-glycol-amide-Exatecan
  • HY-43565C
    (1S,9R)-Ac-Exatecan

    		Drug Intermediate Cancer
    (1S,9R)-Ac-Exatecan is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM) .
    (1S,9R)-Ac-Exatecan
  • HY-160885
    NH2-Gly-PAB-Exatecan-D-glucuronic acid

    		ADC Payload Others
    NH2-Gly-PAB-Exatecan-D-glucuronic acid (Compound 8) is an intermediate, which reacts with NHS group to form drug-linker conjugate for ADC, Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179) .
    NH2-Gly-PAB-Exatecan-D-glucuronic acid
  • HY-160885A
    NH2-Gly-PAB-Exatecan-D-glucuronic acid formic

    		ADC Payload Cancer
    NH2-Gly-PAB-Exatecan-D-glucuronic acid formic (Compound 8) is the formic salt form of H2N-Gly-PAB-Exatecan-D-glucuronic acid. H2N-Gly-PAB-Exatecan-D-glucuronic acid formic is an intermediate, which reacts with NHS group to form drug-linker conjugate for ADC, Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179) .
    NH2-Gly-PAB-Exatecan-D-glucuronic acid formic
  • HY-173703
    β-Glu-PAB(CH2NH2)-Exatecan

    		Topoisomerase Drug Intermediate Cancer
    β-Glu-PAB(CH2NH2)-Exatecan (Compound 9a) is a topoisomerase I inhibitor. β-Glu-PAB(CH2NH2)-Exatecan binds to the topoisomerase I-DNA complex to prevent DNA strand reconnection, thereby inducing DNA breakage and cell apoptosis. β-Glu-PAB(CH2NH2)-Exatecan can be specifically cleaved by β-glucuronidase highly expressed in the tumor microenvironment to release Exatecan for cytotoxic effect. β-Glu-PAB(CH2NH2)-Exatecan is also an intermediate of Mal((3S,3aR,6S,6aR) -hexahydrofuro [3, 2-B]furan-3,6-diamine-PEG12)-β -Glu-Pab-Exatecan. β-Glu-PAB(CH2NH2)-Exatecan is promising for research of cancers .
    β-Glu-PAB(CH2NH2)-Exatecan
  • HY-49412
    Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CO-CH3

    		Drug Intermediate Others
    Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CO-CH3 (compound DC-13-C) is an intermediate in the synthesis of Exatecan (HY-13631) derivatives .
    Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CO-CH3
  • HY-46572
    Benzyl 2-cyclopropyl-2-hydroxyacetate

    		ADC Linker Cancer
    Benzyl 2-cyclopropyl-2-hydroxyacetate is an intermediate in the synthesis of ADC linker.The linker composed of Benzyl 2-cyclopropyl-2-hydroxyacetate can be coupled to Exatecan (HY-13631) and combined with antibodies (such as antibody hu2F7) .
    Benzyl 2-cyclopropyl-2-hydroxyacetate
  • HY-W250541
    Fmoc-Gly-NH-CH2-O-Cyclopropane-CH2COOH

    		ADC Linker Cancer
    Fmoc-Gly-NH-CH2-O-Cyclopropane-CH2COOH is an intermediate in the synthesis of ADC linker.The linker composed of Benzyl 2-cyclopropyl-2-hydroxyacetate can be coupled to Exatecan (HY-13631) and combined with antibodies (such as antibody hu2F7) .
    Fmoc-Gly-NH-CH2-O-Cyclopropane-CH2COOH

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: