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Results for "

Integrin β2

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Inhibitory Antibodies

5

Recombinant Proteins

2

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-125792
    Nexinhib20

    		Reactive Oxygen Species (ROS) Ras Integrin Cardiovascular Disease Inflammation/Immunology
    Nexinhib20 is an inhibitor that targets the interactions of Rab27a-JFC1 (IC50: 2.6 μM) and Rac-1-GTP. Nexinhib20 can inhibit neutrophil exocytosis, adhesion, and β2 integrin activation, and has anti-inflammatory activity. Nexinhib20 can be used in the research of diseases such as systemic inflammation and myocardial ischemia-reperfusion injury [2].
    Nexinhib20
  • HY-P991604
    MLN2201

    YFC51.1; LDP-01

    		 Integrin Inflammation/Immunology
    MLN2201 is a humanized monoclonal antibody inhibitor, targeting Integrin β2. MLN2201 inhibits the reperfusion injury after stroke and can be used for inflammatory diseases like ischemic stroke research [2].
    MLN2201
  • HY-177318
    αLβ2 integrin-IN-1

    		Integrin Inflammation/Immunology
    αLβ2 integrin-IN-1 (example 1) is an αLβ2 integrin mediated cell adhesion inhibitor that can be used for the study of αLβ2 integrin mediated inflammatory conditions .
    αLβ2 integrin-IN-1
  • HY-175288
    αMβ2 integrin agonist-1

    		Integrin JNK ERK Inflammation/Immunology Cancer
    αMβ2 integrin agonist-1 (Compound 8) is a highly selective αMβ2 integrin agonist with anti-inflammatory activity (EC50=1.4 nM). αMβ2 integrin agonist-1 activates integrin-mediated cell adhesion and JNK/ERK signaling. αMβ2 integrin agonist-1 induces tumor-associated macrophage repolarization and enhances antitumor T-cell immune responses. αMβ2 integrin agonist-1 is promising for research of cancers and chronic inflammatory diseases (e.g., pancreatic cancer, rheumatoid arthritis) .
    αMβ2 integrin agonist-1
  • HY-123277
    IMB-10

    		Integrin Inflammation/Immunology
    IMB-10 is an αMβ2 integrin ligand. IMB-10 inhibits αMβ2-dependent migration and inflammation-induced neutrophil emigration .
    IMB-10
  • HY-175286
    α4β1 antagonist-1

    		Integrin ERK Inflammation/Immunology Cancer
    α4β1 antagonist-1 (Compound 4) is a highly selective α4β1 integrin antagonist (IC50=15 nM). α4β1 antagonist-1 inhibits integrin-mediated cell adhesion and ERK1/2 signaling activation. α4β1 antagonist-1 also exhibits partial agonism toward αMβ2 integrin (EC50=23 nM). α4β1 antagonist-1 is promising for research of chronic inflammatory diseases (e.g., rheumatoid arthritis, multiple sclerosis) and cancers .
    α4β1 antagonist-1
  • HY-139137
    N-Acetyl-S-geranylgeranyl-L-cysteine

    AGGC

    		 DNA Methyltransferase Integrin Cancer
    N-Acetyl-S-geranylgeranyl-L-cysteine is a Methyltransferase inhibitor. N-Acetyl-S-geranylgeranyl-L-cysteine inhibits beta 2 integrin-induced actin polymerization with an IC50 of 45 nM .
    N-Acetyl-S-geranylgeranyl-L-cysteine

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