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Pathways Recommended: Antibody-drug Conjugate/ADC Related
Results for "

IgG1λ monoclonal antibody

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

14

Inhibitory Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99039
    Oleclumab
    1 Publications Verification

    MEDI9447

    		 CD73 Cancer
    Oleclumab (MEDI9447) is a human IgG1λ monoclonal antibody targeting CD73 and inhibits the exonuclease activity of the extracellular enzyme CD73. Oleclumab can adjust the composition of bone marrow and lymphoid infiltrating leukocyte populations in the tumor microenvironment and has anti-tumor activity .
    Oleclumab
  • HY-P9952
    Belimumab
    4 Publications Verification

    LymphoStat B

    		 TNF Receptor CD20 Inflammation/Immunology Cancer
    Belimumab (LymphoStat B) is a humanized IgG1λ monoclonal antibody against B-lymphocyte stimulator (BLyS) protein. Belimumab antagonizes BLyS activity in autoimmune diseases and B-lymphocyte malignancies. Belimumab can be used for systemic lupus erythematosus (SLE) research . The component ratio of this product is Active ingredient: Excipients = 1:1.0-1:1.2.
    Belimumab
  • HY-P99322
    Tesidolumab

    LFG316; Anti-Human C5 Recombinant antibody

    		 Complement System Inflammation/Immunology
    Tesidolumab (LFG316) is a fully-human IgG1/λ anti-C5 monoclonal antibody of 143 kDa (without glycosylation). Tesidolumab (LFG316) blocks cleavage of C5 and prevents subsequent formation of the membrane attack complex .
    Tesidolumab
  • HY-P99730
    Mezagitamab
    1 Publications Verification

    TAK-079

    		 CD38 Apoptosis Inflammation/Immunology Cancer
    Mezagitamab (TAK-079) is a IgG1λ anti-CD38 monoclonal antibody. Mezagitamab depletes tumor cells expressing CD38 through antibody and complement dependent cytotoxicity. Mezagitamab has potential application in relapsed/refractory multiple myeloma (RRMM) and idiopathic thrombocytopenic purpura (ITP) .
    Mezagitamab
  • HY-P990014
    Danburstotug

    IMC-001; STI-3031

    		 PD-1/PD-L1 Inflammation/Immunology Cancer
    Danburstotug (IMC-001) is an IgG1-lambda anti-CD274 (PDL1, B7 homologue 1, B7H1) human monoclonal antibody. Danburstotug also is immunostimulant and antineoplastic .
    Danburstotug
  • HY-P991202
    Anti-TSHR Antibody (M22)

    		TSH Receptor Endocrinology
    Anti-TSHR Antibody (M22) is a humanized IgG1 monoclonal antibody that targets thyrotropin receptor (TSHR). Anti-TSHR Antibody (M22) inhibits the binding of TSH and TSHR. Recommend Isotype Controls: Human IgG1 lambda, Isotype Control (HY-P99992) .
    Anti-TSHR Antibody (M22)
  • HY-P991717
    Sunakiment

    		Interleukin Related Inflammation/Immunology Cancer
    Sunakiment is a humanized IgG1λ monoclonal antibody inhibitor targeting Thymic stromal lymphopoietin (TSLP). Sunakiment can be used for inflammatory and immune system disorders like ulcerative colitis, rheumatoid arthritis and allergy and cancers research .
    Sunakiment
  • HY-P991651
    MEDI4212

    		Fc Receptor (FcR) Inflammation/Immunology
    MEDI4212 is a humanized IgG1λ monoclonal antibody inhibitor targeting IgE. MEDI4212 potently inhibits human IgE-mediated functional responses through its receptor FcεRI, such as calcium signaling, β-hexosaminidase release and phagocytosis. MEDI4212 prevents the binding of IgE to CD23 with an IC50 of 8 nM. MEDI4212 can be used severe asthma research .
    MEDI4212
  • HY-P991115
    Adimanebart

    		Trk Receptor Others
    Amdokitug is an anti-MUSK human IgG1 λ monoclonal antibody. Recommend Isotype Controls: Human IgG1 Lambda2, Isotype Control (HY-P990096) .
    Adimanebart
  • HY-P991422
    Stromab

    DS9231; TS-23; CSL-301

    		 PAI-1 Cardiovascular Disease
    Stromab (DS9231; TS-23; CSL-301) is a human IgG1 monoclonal antibody (mAb) targeting Serpin F2. Stromab can be used in schaemic stroke, Pulmonary embolism, Myocardial infarction and Thrombosis research. Recommended isotype control: Human IgG1 lambda, Isotype Control (HY-P99992) .
    Stromab
  • HY-P990006
    Duvakitug

    TEV-48574

    		 TNF Receptor Inflammation/Immunology
    Duvakitug (TEV-48574) is a humanized IgG1-λ2 monoclonal antibody targeting to TNFSF15/TL1A. Duvakitug' main expression system is CHOK1SV cells endogenously expressing glutamine synthetase (GS). Duvakitug can be used in the study of Crohn's Disease (CD) .
    Duvakitug
  • HY-P991402
    BI-1910

    		TNF Receptor Cancer
    BI-1910 is a human monoclonal antibody (mAb) targeting TNFRSF1B. BI-1910 enhances T cell activation and induces CD8 T cell-dependent anti-tumor effects. BI-1910 can be used in solid tumors research. Recommended isotype control: Human IgG1 lambda, Isotype Control (HY-P99992) .
    BI-1910
  • HY-P990015
    Tobevibart

    VIR-3434

    		 HBV Infection
    Tobevibart (VIR-3434) is a human IgG1 lambda monoclonal antibody against hepatitis B virus (HBV) surface antigen (HBsAg). Tobevibart shows potent neutralization against HBsAg from all HBV genotypes in vitro and inhibits viral entry of HBV and hepatitis delta virus (HDV). Recommend Isotype Controls: Human IgG1 lambda2, Isotype Control (HY-P990096) .
    Tobevibart

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