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Results for "

Ifosfamide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Bcl-2 Family (2) Caspase (2) CXCR (2) DNA Alkylator/Crosslinker (7) Drug Metabolite (1) Fluorescent Dye (1) Guanylate Cyclase (1) Isotope-Labeled Compounds (3) Melanocortin Receptor (1) Monoamine Oxidase (1) Neuropeptide Y Receptor (3) NO Synthase (1) Parasite (2) Reference Standards (2)
By Research Areas:	Cancer (15) Infection (1) Metabolic Disease (2) Neurological Disease (4)

Inhibitors & Agonists

Peptides

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17419

*Ifosfamide* 5+ Cited Publications	DNA Alkylator/Crosslinker	Cancer
Ifosfamide is an alkylating chemotherapeutic agent with activity against a wide range of tumors.

HY-17419S1

Ifosfamide-d4	Isotope-Labeled Compounds DNA Alkylator/Crosslinker	Cancer
Ifosfamide-d₄ is the deuterium labeled Ifosfamide. Ifosfamide is an alkylating chemotherapeutic agent with activity against a wide range of tumors .

HY-14798

Palifosfamide 2 Publications Verification Isophosphoramide mustard; IPM; ZIO-201	DNA Alkylator/Crosslinker Drug Metabolite	Cancer
Palifosfamide is a novel DNA alkylator and the active metabolite of ifosfamide, with antitumor activity.

HY-16232

Glufosfamide D 19575; GlucosylIfosfamide mustard	Apoptosis Caspase Bcl-2 Family	Cancer
Glufosfamide is a glucose-conjugated alkylating cytotoxic agent and a derivative of Ifosfamide (HY-17419). Glufosfamide induces apoptosis frequency and increase the expression of caspase-9 and caspase-3 in cancer cells. Glufosfamide shows great anti-tumor activity in MiaPaCa-2-RFP mouse model. Glufosfamide can be used for the study of hepatocellular carcinoma, prostate cancer and pancreatic carcinoma .

HY-B1359

Methylene blue trihydrate Maximum Cited Publications 19 Publications Verification C.I. Basic Blue 9 trihydrate	Guanylate Cyclase Monoamine Oxidase NO Synthase Parasite	Infection Neurological Disease Cancer
Methylene blue trihydrate (C.I. Basic Blue 9 trihydrate) is a guanylyl cyclase (sGC), monoamine oxidase A (MAO-A) and NO synthase (NOS) inhibitor. Methylene blue trihydrate is a vasopressor and is often used as a dye in several medical procedures. Methylene blue trihydrate has antinociception, antimalarial, antidepressant and anxiolytic activity effects. Methylene Blue trihydrate has the potential for methemoglobinemias, neurodegenerative disorders and ifosfamide-induced encephalopathytreatment .

HY-17419R

Ifosfamide (Standard)	Reference Standards DNA Alkylator/Crosslinker	Cancer
Ifosfamide (Standard) is the analytical standard of Ifosfamide. This product is intended for research and analytical applications. Ifosfamide is an alkylating chemotherapeutic agent with activity against a wide range of tumors.

HY-17419S2

Ifosfamide-d4-1	DNA Alkylator/Crosslinker Isotope-Labeled Compounds	Cancer
Ifosfamide-d₄-1 is deuterium-labeled Ifosfamide (HY-17419) .

HY-17419S

*2’-Oxo Ifosfamide-d4*	Isotope-Labeled Compounds DNA Alkylator/Crosslinker	Cancer
2’-Oxo Ifosfamide-d₄ is the deuterium labeled Ifosfamide. Ifosfamide is an alkylating chemotherapeutic agent with activity against a wide range of tumors .

HY-17419A

(R)-Ifosfamide	Others	Cancer
(R)-Ifosfamide is a chemotherapeutic agent primarily used in the treatment of aggressive tumors such as rhabdomyosarcoma, exhibiting alkylating activity that interferes with DNA replication.

HY-114577

Palifosfamide tromethamine Isophosphoramide mustard tromethamine; IPM tromethamine; ZIO-201 tromethamine	DNA Alkylator/Crosslinker	Cancer
Palifosfamide (tromethamine) is a synthetic alkylating agent with potential antineoplastic activity. As the stabilized active metabolite of ifosfamide, palifosfamide (tromethamine) irreversibly alkylates and crosslinks DNA through GC base pairs. This leads to an inhibition of DNA replication and ultimately cell death. Compared to ifosfamide, palifosfamide (tromethamine) is less toxic.

HY-P4154

Bevonescein ALM-488	Fluorescent Dye	Neurological Disease Cancer
Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves .

HY-P1103

CTCE-9908 1 Publications Verification	CXCR	Cancer
CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-P1103A

CTCE-9908 TFA	CXCR	Cancer
CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-16232R

Glufosfamide (Standard)	Reference Standards Apoptosis Bcl-2 Family Caspase	Cancer
Glufosfamide (Standard) is the analytical standard of Glufosfamide. This product is intended for research and analytical applications. Glufosfamide is a glucose-conjugated alkylating cytotoxic agent and a derivative of Ifosfamide (HY-17419). Glufosfamide induces apoptosis frequency and increase the expression of caspase-9 and caspase-3 in cancer cells. Glufosfamide shows great anti-tumor activity in MiaPaCa-2-RFP mouse model. Glufosfamide can be used for the study of hepatocellular carcinoma, prostate cancer and pancreatic carcinoma .

HY-P10026

Nisotirostide LY-3457263	Neuropeptide Y Receptor	Metabolic Disease
Nisotirotide (LY-3457263) is a subcutaneous injectable NPY2 receptor agonist. By mimicking peptide YY (PYY), Nisotirotide inhibits appetite and can be used in the research of diseases such as obesity and diabetes .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-P11293

DOTA-GGNle-CycMSHhex	Melanocortin Receptor	Cancer
DOTA-GGNle-CycMSHhex is a melanocortin-1 receptor (MC1R)-targeting peptide that can be radionuclide-labeled for melanoma imaging .

HY-P1321

GR231118 1229U91; GW1229	Neuropeptide Y Receptor	Neurological Disease
GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pK_i= 8.8) .

HY-P1321A

GR231118 TFA 1229U91 TFA; GW1229 TFA	Neuropeptide Y Receptor	Neurological Disease
GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pK_i= 8.8) .

Cat. No.	Product Name	Target	Research Area

HY-P4154

Bevonescein ALM-488	Fluorescent Dye	Neurological Disease Cancer
Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves .

HY-P1103

CTCE-9908 1 Publications Verification	CXCR	Cancer
CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-P10026

Nisotirostide LY-3457263	Neuropeptide Y Receptor	Metabolic Disease
Nisotirotide (LY-3457263) is a subcutaneous injectable NPY2 receptor agonist. By mimicking peptide YY (PYY), Nisotirotide inhibits appetite and can be used in the research of diseases such as obesity and diabetes .

HY-P4070

Insulin icodec	Peptides	Metabolic Disease
Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec can be used for the research of type 2 diabetes .

HY-P1103A

CTCE-9908 TFA	CXCR	Cancer
CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-P11293

DOTA-GGNle-CycMSHhex	Melanocortin Receptor	Cancer
DOTA-GGNle-CycMSHhex is a melanocortin-1 receptor (MC1R)-targeting peptide that can be radionuclide-labeled for melanoma imaging .

HY-P1321

GR231118 1229U91; GW1229	Neuropeptide Y Receptor	Neurological Disease
GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pK_i= 8.8) .

HY-P1321A

GR231118 TFA 1229U91 TFA; GW1229 TFA	Neuropeptide Y Receptor	Neurological Disease
GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pK_i= 8.8) .

Cat. No.	Product Name	Chemical Structure

HY-17419S1

Ifosfamide-d4
Ifosfamide-d₄ is the deuterium labeled Ifosfamide. Ifosfamide is an alkylating chemotherapeutic agent with activity against a wide range of tumors .

HY-17419S2

Ifosfamide-d4-1
Ifosfamide-d₄-1 is deuterium-labeled Ifosfamide (HY-17419) .

HY-17419S

*2’-Oxo Ifosfamide-d4*
2’-Oxo Ifosfamide-d₄ is the deuterium labeled Ifosfamide. Ifosfamide is an alkylating chemotherapeutic agent with activity against a wide range of tumors .

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