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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

IL-5 Antibody

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Interleukin Related (10) Apoptosis (2) c-Fms (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Inflammation/Immunology (12)

Inhibitors & Agonists

Inhibitory Antibodies

Antibodies

Targets Recommended: ADC Antibody Antibody-Drug Conjugates (ADCs) Interleukin Related ADC Linker IRAK PROTAC-Linker Conjugates for PAC Itk

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990213

Anti-Mouse/Human IL-5 Antibody (TRFK5)	Interleukin Related	Inflammation/Immunology
Anti-Mouse/Human IL-5 Antibody (TRFK5) is a rat-derived anti-mouse *IL-5* IgG1 κ type antibody inhibitor. Anti-Mouse/Human IL-5 Antibody (TRFK5) can significantly decrease eosinophils. Anti-Mouse/Human IL-5 Antibody (TRFK5) shows potent anti- inflammation effect on pulmonary inflammation and asthma .

HY-P9945A

Mepolizumab (anti-IL5)	Interleukin Related	Inflammation/Immunology
Mepolizumab (anti-IL5) is a humanized monoclonal antibody that binds to and neutralizes interleukin-5 (IL-5), the major cytokine involved in eosinophil proliferation, activation, and survival. Mepolizumab can be used for the research of eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma .

HY-P9945

Mepolizumab SB 240563	Interleukin Related	Cardiovascular Disease Inflammation/Immunology
Mepolizumab (SB 240563) is a humanized monoclonal antibody that binds to and neutralizes interleukin-5 (IL-5), the major cytokine involved in eosinophil proliferation, activation, and survival. Mepolizumab can be used for the research of eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma .

HY-P9949

Reslizumab Sch 55700	Interleukin Related	Inflammation/Immunology
Reslizumab (Sch 55700) is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma. Reslizumab is effective in neutralizing the function of *IL-5. Reslizumab has high binding affinity for human IL-5, with K_D* values of 109 pM and 4.3 pM in the the Biacore surface plasmon resonance and Kinetic Exclusion Assay, respectively .

HY-P990094

Trabikibart CSL311	c-Fms	Inflammation/Immunology
Trabikibart (CSL311), a βc (CSF2RB)-specific, fully human monoclonal antibody, binds to a unique epitope that is specific to the cytokine-binding site of the human βc receptor. Trabikibart has picomolar binding affinity for the human βc receptor. Trabikibart is a potent inhibitor of the combined effects of IL-3, GM-CSF and IL-5 on the survival of eosinophils. Trabikibart has the potential for chronic inflammatory diseases research .

HY-P9923A

Benralizumab (anti-IL5RA ) MEDI-563 (anti-IL5RA ); BIW-8405 (anti-IL5RA )	Interleukin Related	Inflammation/Immunology
Benralizumab (anti-IL5RA ) (MEDI-563 (anti-IL5RA ); BIW-8405 (anti-IL5RA )) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma study .

HY-P990452

Anti-IL-5 Antibody	Interleukin Related	Inflammation/Immunology
Anti-IL-5 Antibody is a CHO-expressed humanized antibody that targets *IL-5. The Anti-IL-5* Antibody is composed of huIgG4 heavy chains and huκ light chains, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-IL-5 Antibody can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).

HY-P991144

Lasrekibart	Interleukin Related	Inflammation/Immunology
Lasrekibart is a humanized monoclonal antibody targeting human interleukin 5 (IL-5). Lasrekibart specifically binds to *IL-5, blocking the interaction between IL-5* and its receptor, thus exerting immunosuppressive and anti-inflammatory activities. Lasrekibart is promising for research of allergic and inflammatory diseases, such as asthma .

HY-P990058

Varokibart	Interleukin Related	Inflammation/Immunology
Varokibart (TEV-53275) is a human IgG4λ antibody targeting *IL5* .

HY-P991599

SHR-1703	Interleukin Related	Inflammation/Immunology
SHR-1703 is a long-acting humanized anti-IL-5 IgG1 monoclonal antibody. SHR-1703 can selectively recognize and bind to *IL-5, blocking the binding of IL-5* to the α chain of the receptor on the surface of eosinophils, thereby inhibiting the proliferation, activation, and migration of eosinophils, and ultimately reducing eosinophil-mediated inflammation and damage. SHR-1703 can be used in the research of eosinophil-related diseases, such as eosinophilic asthma. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P9923

Benralizumab MEDI-563; BIW-8405	Interleukin Related Apoptosis	Inflammation/Immunology Cancer
Benralizumab (MEDI-563) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma .

HY-P99371

Lirentelimab AK002; Antolimab	Apoptosis	Inflammation/Immunology
Lirentelimab (AK002) is a humanized IgG1 monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). Lirentelimab induces cell apoptosis of IL-5-activated eosinophils and inhibits IgE-mediated mast cell activation. Lirentelimab can be used for the research of eosinophilic gastritis and duodenitis .

Cat. No.	Product Name	Target	Research Area

HY-P990213

Anti-Mouse/Human IL-5 Antibody (TRFK5)	Interleukin Related	Inflammation/Immunology
Anti-Mouse/Human IL-5 Antibody (TRFK5) is a rat-derived anti-mouse *IL-5* IgG1 κ type antibody inhibitor. Anti-Mouse/Human IL-5 Antibody (TRFK5) can significantly decrease eosinophils. Anti-Mouse/Human IL-5 Antibody (TRFK5) shows potent anti- inflammation effect on pulmonary inflammation and asthma .

HY-P9945A

Mepolizumab (anti-IL5)	Interleukin Related	Inflammation/Immunology
Mepolizumab (anti-IL5) is a humanized monoclonal antibody that binds to and neutralizes interleukin-5 (IL-5), the major cytokine involved in eosinophil proliferation, activation, and survival. Mepolizumab can be used for the research of eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma .

HY-P9945

Mepolizumab SB 240563	Interleukin Related	Cardiovascular Disease Inflammation/Immunology
Mepolizumab (SB 240563) is a humanized monoclonal antibody that binds to and neutralizes interleukin-5 (IL-5), the major cytokine involved in eosinophil proliferation, activation, and survival. Mepolizumab can be used for the research of eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma .

HY-P9949

Reslizumab Sch 55700	Interleukin Related	Inflammation/Immunology
Reslizumab (Sch 55700) is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma. Reslizumab is effective in neutralizing the function of *IL-5. Reslizumab has high binding affinity for human IL-5, with K_D* values of 109 pM and 4.3 pM in the the Biacore surface plasmon resonance and Kinetic Exclusion Assay, respectively .

HY-P990094

Trabikibart CSL311	c-Fms	Inflammation/Immunology
Trabikibart (CSL311), a βc (CSF2RB)-specific, fully human monoclonal antibody, binds to a unique epitope that is specific to the cytokine-binding site of the human βc receptor. Trabikibart has picomolar binding affinity for the human βc receptor. Trabikibart is a potent inhibitor of the combined effects of IL-3, GM-CSF and IL-5 on the survival of eosinophils. Trabikibart has the potential for chronic inflammatory diseases research .

HY-P9923A

Benralizumab (anti-IL5RA ) MEDI-563 (anti-IL5RA ); BIW-8405 (anti-IL5RA )	Interleukin Related	Inflammation/Immunology
Benralizumab (anti-IL5RA ) (MEDI-563 (anti-IL5RA ); BIW-8405 (anti-IL5RA )) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma study .

HY-P990452

Anti-IL-5 Antibody	Interleukin Related	Inflammation/Immunology
Anti-IL-5 Antibody is a CHO-expressed humanized antibody that targets *IL-5. The Anti-IL-5* Antibody is composed of huIgG4 heavy chains and huκ light chains, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-IL-5 Antibody can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).

HY-P991144

Lasrekibart	Interleukin Related	Inflammation/Immunology
Lasrekibart is a humanized monoclonal antibody targeting human interleukin 5 (IL-5). Lasrekibart specifically binds to *IL-5, blocking the interaction between IL-5* and its receptor, thus exerting immunosuppressive and anti-inflammatory activities. Lasrekibart is promising for research of allergic and inflammatory diseases, such as asthma .

HY-P990058

Varokibart	Interleukin Related	Inflammation/Immunology
Varokibart (TEV-53275) is a human IgG4λ antibody targeting *IL5* .

HY-P991599

SHR-1703	Interleukin Related	Inflammation/Immunology
SHR-1703 is a long-acting humanized anti-IL-5 IgG1 monoclonal antibody. SHR-1703 can selectively recognize and bind to *IL-5, blocking the binding of IL-5* to the α chain of the receptor on the surface of eosinophils, thereby inhibiting the proliferation, activation, and migration of eosinophils, and ultimately reducing eosinophil-mediated inflammation and damage. SHR-1703 can be used in the research of eosinophil-related diseases, such as eosinophilic asthma. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P9923

Benralizumab MEDI-563; BIW-8405	Interleukin Related Apoptosis	Inflammation/Immunology Cancer
Benralizumab (MEDI-563) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma .

HY-P99371

Lirentelimab AK002; Antolimab	Apoptosis	Inflammation/Immunology
Lirentelimab (AK002) is a humanized IgG1 monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). Lirentelimab induces cell apoptosis of IL-5-activated eosinophils and inhibits IgE-mediated mast cell activation. Lirentelimab can be used for the research of eosinophilic gastritis and duodenitis .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P83661

	IL-3RB Antibody(YA3396) CSF2RB; IL3RB; IL5RB; SMDP5; CDw131; CD131; betaGMR	WB, IHC-P, FC, ELISA	Human, Mouse, Rat
	IL-3RB Antibody is a non-conjugated and mouse origined monoclonal antibody about 97 kDa, targeting to IL-3RB. It can be used for WB,IHC-P,FC,ELISA assays with tag free, in the background of Huma,Mouse,Rat.

HY-P85018

	IL-5 Antibody (YA4710) IL5; Interleukin-5; IL-5; B-cell differentiation factor I; EosinophIL differentiation factor; T-cell replacing factor; TRF; IL-5 nanobody	ELISA	Human
	IL-5 Antibody (YA4710) is a mouse-derived and non-conjugated monoclonal antibody, targeting to IL-5. It can be applicated for ELISA assays, in the background of human.

HY-P81483

	IL-5 Receptor alpha Antibody (YA1228) IL-5 Receptor alpha; interleukin 5 receptor; alpha; IL5R; CD125; CDw125; HSIL5R3	IHC-P	Human
	IL-5 Receptor alpha Antibody (YA1228) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1228), targeting IL-5 Receptor alpha. IL-5 Receptor alpha Antibody (YA1228) can be used for IHC-P experiment in human background.

HY-P87049

	REIIBP/NSD2 Antibody (YA6742) FLJ23286 Antibody; IL5 promoter REII region binding protein Antibody; KIAA1090 Antibody; MGC176638 Antibody; MMSET Antibody; MMSET type II Antibody; Multiple myeloma SET domain containing protein type III Antibody; Multiple myeloma SET domain protein Antibody; Multiple myeloma SET domain-containing protein Antibody; NSD 2 Antibody; FLJ23286 Antibody; IL5 promoter REII region binding protein Antibody; KIAA1090 Antibody; MGC176638 Antibody; MMSET Antibody; MMSET type II Antibody; Multiple myeloma SET domain containing protein type III Antibody; Multiple myeloma SET domain protein Antibody; Multiple myeloma SET domain-containing protein Antibody; NSD 2 Antibody; NSD2 Antibody; NSD2_HUMAN Antibody; Nuclear receptor binding SET domain protein 2 Antibody; Nuclear SET domain-containing protein 2 Antibody; Probable histone-lysine N-methyltransferase NSD2 Antibody; Protein trithorax-5 Antibody; REIIBP Antibody; Trithorax/ash1 related protein 5 Antibody; TRX5 Antibody; TRX5 protein Antibody; WHS Antibody; Whsc1 Antibody; Wolf Hirschhorn syndrome candidate 1 Antibody; Wolf Hirschhorn syndrome candidate 1 protein Antibody; Wolf-Hirschhorn syndrome candidate 1 protein Antibody	WB, IHC-P	Human, Mouse, Rat

HY-P84960

	IL-3RB Antibody IL-3R common β chain; CDw131; Beta-C Antibody; CD131 Antibody; CDw131 Antibody; Colony stimulating factor 2 receptor beta Antibody; Colony stimulating factor 2 receptor beta low affinity; granulocyte macrophage; Antibody; Common beta chain Antibody; Csf2rb Antibody; Cytokine receptor common beta chain Antibody; Cytokine receptor common beta chain precursor; CDw131 antigen; Antibody; Cytokine receptor common subunit beta Antibody; GM CSF/IL 3/IL 5 receptor common beta chain Antibody; GM-CSF/IL-3/IL-5 receptor common beta subunit Antibody; granulocyte-macrophage colony-stimulating factor receptor; beta Antibody; IL3RB Antibody; IL3RB_HUMAN Antibody; IL5RB Antibody; Interleukin 3 receptor; beta Antibody; Interleukin 3 receptor/granulocyte macrophage colony stimulating factor 3 receptor beta; high affinity; Antibody; Interleukin 5 receptor; beta Antibody; SMDP5 Antibody; stimulating factor 3 receptor; beta; high affinity; Antibody;
	IL-3RB Antibody is a non-conjugated antibody, targeting to CD131.

HY-P84264

	IL-3RB Antibody (YA3961) CSF2RB; IL3RB; IL5RB; SMDP5; CDw131; betaGMR	WB, IHC-P, FC, ELISA	Human, Mouse, Rat
	IL-3RB Antibody (YA3961) is a mouse-derived and non-conjugated IgG1 antibody, targeting to CD131. It can be applicated for WB, IHC-P, FC, ELISA assays, in the background of human, mouse, rat.

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