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Human liver expressed antimicrobial peptide2

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P5645
    LEAP-2
    1 Publications Verification

    Human liver expressed antimicrobial peptide-2

    		 GHSR Interleukin Related IFNAR TNF Receptor Bacterial Infection Metabolic Disease Inflammation/Immunology
    LEAP-2 (Human liver expressed antimicrobial peptide-2) is a GHS-R1a antagonist, with an IC50 of 6.0 nM. LEAP-2 suppresses the orexigenic effect of ghrelin. LEAP-2 attenuates ghrelin-induced growth hormone (GH) release and reduces basal food intake. LEAP-2 exhibits antimicrobial activity against microbial model organisms. LEAP-2 can be used for the study of obesity and infection .
    LEAP-2

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