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Hesperidin

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By Targets:	Akt (2) Apoptosis (4) Autophagy (2) Endogenous Metabolite (2) ERK (2) HIV (1) Integrin (2) Isotope-Labeled Compounds (1) NF-κB (2) PI3K (2) PKC (2) PPAR (2) Reactive Oxygen Species (ROS) (2) Reference Standards (3) Sirtuin (2) STAT (2) Toll-like Receptor (TLR) (2)
By Research Areas:	Cancer (4) Cardiovascular Disease (1) Infection (2) Inflammation/Immunology (6) Metabolic Disease (1) Neurological Disease (1)

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Natural
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1

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*Hesperidin* 20+ Cited Publications Hesperetin 7-rutinoside	Apoptosis Autophagy Reactive Oxygen Species (ROS) Endogenous Metabolite	Cancer
Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities .

Hesperidin methylchalcone 1 Publications Verification	NF-κB	Inflammation/Immunology
Hesperidin methylchalcone (Hesperidin methyl chalcone) is an orally active flavonoid that has analgesic, anti-inflammatory and antioxidant properties. Hesperidin methylchalcone exhibits vasoprotective activity. Hesperidin methylchalcone inhibits oxidative stress, cytokine production and NF-κB activation. Hesperidin methylchalcone can be used for the research of gout disease .

Methyl-Hesperidin	Others	Inflammation/Immunology
Methyl-Hesperidin is a vasodilating agent .

Phellopterin	Akt Sirtuin Integrin STAT PI3K Apoptosis ERK PPAR PKC Toll-like Receptor (TLR) HIV	Inflammation/Immunology
Phellopterin, an orally active furocoumarin with multiple biological activities. Phellopterin is a partial agonist of the central benzodiazepine receptors. Phellopterin exerts anti-inflammatory effects by upregulating SIRT1, downregulating ICAM-1 (reducing chronic inflammation, aiding diabetic ulcer healing), inhibiting STAT3 phosphorylation (easing atopic dermatitis inflammation), regulating Akt/PKC pathways (lowering TNF-α-induced VCAM-1 to block monocyte adhesion), and inhibiting TLR4/NF-κB pathway and macrophage M2 polarization (alleviating colitis-related cancers). Phellopterin suppresses ovarian cancer progression via inhibiting the PU.1/CLEC5A/PI3K-AKT loop (inducing cell cycle arrest, apoptosis, DNA damage). Phellopterin alleviates murine diabetes by promoting adipocyte differentiation and increasing PPARγ. Phellopterin also has anti-HSV-1 activity. Phellopterin can be used for studying anti-inflammation, anti-cancer (e.g., ovarian cancer, colitis cancer), blood glucose lowering, anti-diabetes, and anti-virus .

Hesperidin methylchalcone (Standard)	NF-κB	Inflammation/Immunology
Hesperidin methylchalcone (Standard) is the analytical standard of Hesperidin methylchalcone. This product is intended for research and analytical applications. Hesperidin methylchalcone (Hesperidin methyl chalcone) is an orally active flavonoid that has analgesic, anti-inflammatory and antioxidant properties. Hesperidin methylchalcone exhibits vasoprotective activity. Hesperidin methylchalcone inhibits oxidative stress, cytokine production and NF-κB activation. Hesperidin methylchalcone can be used for the research of gout disease .

Hesperidin dihydrochalcone	Others	Infection
Hesperidin dihydrochalcone is a non-toxic, high-sweetness, low-calorie sweetener. Hesperidin dihydrochalcone has many biological activities such as anti-oxidation, protection of liver and kidney, bacteriostasis and improvement of gastrointestinal tract .

Hesperidin (Standard) Hesperetin 7-rutinoside (Standard)	Reference Standards Apoptosis Autophagy Reactive Oxygen Species (ROS) Endogenous Metabolite	Cancer
Hesperidin (Standard) is the analytical standard of Hesperidin. This product is intended for research and analytical applications. Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities .

*Methyl-Hesperidin* (Standard)**	Reference Standards Others	Inflammation/Immunology
Methyl-Hesperidin (Standard) is the analytical standard of Methyl-Hesperidin. This product is intended for research and analytical applications. Methyl-Hesperidin is a vasodilating agent[1].

Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2	Isotope-Labeled Compounds	Cancer
Alpha Feto Protein, Arg- ¹³C₃₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled Alpha Feto Protein.

Phellopterin (Standard)	Reference Standards Akt Sirtuin Integrin STAT PI3K Apoptosis ERK PPAR PKC Toll-like Receptor (TLR)	Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Phellopterin (Standard) is the analytical standard of Phellopterin. Phellopterin, an orally active furocoumarin with multiple biological activities. Phellopterin is a partial agonist of the central benzodiazepine receptors. Phellopterin exerts anti-inflammatory effects by upregulating SIRT1, downregulating ICAM-1 (reducing chronic inflammation, aiding diabetic ulcer healing), inhibiting STAT3 phosphorylation (easing atopic dermatitis inflammation), regulating Akt/PKC pathways (lowering TNF-α-induced VCAM-1 to block monocyte adhesion), and inhibiting TLR4/NF-κB pathway and macrophage M2 polarization (alleviating colitis-related cancers). Phellopterin suppresses ovarian cancer progression via inhibiting the PU.1/CLEC5A/PI3K-AKT loop (inducing cell cycle arrest, apoptosis, DNA damage). Phellopterin alleviates murine diabetes by promoting adipocyte differentiation and increasing PPARγ. Phellopterin also has anti-HSV-1 activity. Phellopterin can be used for studying anti-inflammation, anti-cancer (e.g., ovarian cancer, colitis cancer), blood glucose lowering, anti-diabetes, and anti-virus.

Cat. No.	Product Name	Category	Target	Chemical Structure

*Hesperidin* 20+ Cited Publications Hesperetin 7-rutinoside	Structural Classification Flavonoids Classification of Application Fields Anti-aging Flavonones Source classification Rutaceae Plants Endogenous metabolite Citrus Disease Research Fields Cancer	Apoptosis Autophagy Reactive Oxygen Species (ROS) Endogenous Metabolite
Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities .

Hesperidin methylchalcone 1 Publications Verification	Chalcones Flavonoids Source classification Rutaceae Plants Citrus Inflammation/Immunology Disease Research Fields	NF-κB
Hesperidin methylchalcone (Hesperidin methyl chalcone) is an orally active flavonoid that has analgesic, anti-inflammatory and antioxidant properties. Hesperidin methylchalcone exhibits vasoprotective activity. Hesperidin methylchalcone inhibits oxidative stress, cytokine production and NF-κB activation. Hesperidin methylchalcone can be used for the research of gout disease .

Methyl-Hesperidin	Flavonoids other families Classification of Application Fields Flavonones Source classification Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology	Others
Methyl-Hesperidin is a vasodilating agent .

Phellopterin	Structural Classification Classification of Application Fields Source classification Coumarins Phenylpropanoids Umbelliferae Helogyne apaloidea Nutt. Plants Inflammation/Immunology Disease Research Fields	Akt Sirtuin Integrin STAT PI3K Apoptosis ERK PPAR PKC Toll-like Receptor (TLR) HIV
Phellopterin, an orally active furocoumarin with multiple biological activities. Phellopterin is a partial agonist of the central benzodiazepine receptors. Phellopterin exerts anti-inflammatory effects by upregulating SIRT1, downregulating ICAM-1 (reducing chronic inflammation, aiding diabetic ulcer healing), inhibiting STAT3 phosphorylation (easing atopic dermatitis inflammation), regulating Akt/PKC pathways (lowering TNF-α-induced VCAM-1 to block monocyte adhesion), and inhibiting TLR4/NF-κB pathway and macrophage M2 polarization (alleviating colitis-related cancers). Phellopterin suppresses ovarian cancer progression via inhibiting the PU.1/CLEC5A/PI3K-AKT loop (inducing cell cycle arrest, apoptosis, DNA damage). Phellopterin alleviates murine diabetes by promoting adipocyte differentiation and increasing PPARγ. Phellopterin also has anti-HSV-1 activity. Phellopterin can be used for studying anti-inflammation, anti-cancer (e.g., ovarian cancer, colitis cancer), blood glucose lowering, anti-diabetes, and anti-virus .

Hesperidin methylchalcone (Standard)	Chalcones Flavonoids Source classification Rutaceae Plants Citrus	NF-κB
Hesperidin methylchalcone (Standard) is the analytical standard of Hesperidin methylchalcone. This product is intended for research and analytical applications. Hesperidin methylchalcone (Hesperidin methyl chalcone) is an orally active flavonoid that has analgesic, anti-inflammatory and antioxidant properties. Hesperidin methylchalcone exhibits vasoprotective activity. Hesperidin methylchalcone inhibits oxidative stress, cytokine production and NF-κB activation. Hesperidin methylchalcone can be used for the research of gout disease .

Hesperidin (Standard) Hesperetin 7-rutinoside (Standard)	Structural Classification Flavonoids Flavonones Source classification Rutaceae Plants Endogenous metabolite Citrus	Reference Standards Apoptosis Autophagy Reactive Oxygen Species (ROS) Endogenous Metabolite
Hesperidin (Standard) is the analytical standard of Hesperidin. This product is intended for research and analytical applications. Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities .

*Methyl-Hesperidin* (Standard)**	Structural Classification Flavonoids other families Flavonones Source classification Phenols Polyphenols Plants	Reference Standards Others
Methyl-Hesperidin (Standard) is the analytical standard of Methyl-Hesperidin. This product is intended for research and analytical applications. Methyl-Hesperidin is a vasodilating agent[1].

Phellopterin (Standard)	Structural Classification Source classification Coumarins Phenylpropanoids Umbelliferae Helogyne apaloidea Nutt. Plants	Reference Standards Akt Sirtuin Integrin STAT PI3K Apoptosis ERK PPAR PKC Toll-like Receptor (TLR)
Phellopterin (Standard) is the analytical standard of Phellopterin. Phellopterin, an orally active furocoumarin with multiple biological activities. Phellopterin is a partial agonist of the central benzodiazepine receptors. Phellopterin exerts anti-inflammatory effects by upregulating SIRT1, downregulating ICAM-1 (reducing chronic inflammation, aiding diabetic ulcer healing), inhibiting STAT3 phosphorylation (easing atopic dermatitis inflammation), regulating Akt/PKC pathways (lowering TNF-α-induced VCAM-1 to block monocyte adhesion), and inhibiting TLR4/NF-κB pathway and macrophage M2 polarization (alleviating colitis-related cancers). Phellopterin suppresses ovarian cancer progression via inhibiting the PU.1/CLEC5A/PI3K-AKT loop (inducing cell cycle arrest, apoptosis, DNA damage). Phellopterin alleviates murine diabetes by promoting adipocyte differentiation and increasing PPARγ. Phellopterin also has anti-HSV-1 activity. Phellopterin can be used for studying anti-inflammation, anti-cancer (e.g., ovarian cancer, colitis cancer), blood glucose lowering, anti-diabetes, and anti-virus.

Cat. No.	Product Name	Chemical Structure

Alpha Feto Protein, Arg-13C6,15N4, Lys-13C6,15N2
Alpha Feto Protein, Arg- ¹³C₃₆, ¹⁵N₄, Lys- ¹³C₆, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled Alpha Feto Protein.

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