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Results for "

HRV

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Enterovirus (9) Bacterial (2) Biochemical Assay Reagents (1) EGFR (1) HIV (1) HSP (1) Influenza Virus (3) Interleukin Related (2) Isotope-Labeled Compounds (1) Phosphodiesterase (PDE) (1) PI4K (1) STING (1) Virus Protease (4)
By Research Areas:	Cancer (1) Infection (14) Inflammation/Immunology (5) Neurological Disease (1)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Enterovirus

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-E70370

hrv 3c Protease	Virus Protease	Others
hrv 3c Protease is a protease originated from human rhinoviruses. hrv 3c Protease recognizes the sequence LEVLFQGP and cleaves precisely between the Q and GP residues. hrv 3c Protease can be used to remove additional tags from the target proteins .

HY-106161

Rupintrivir 5 Publications Verification AG7088	Virus Protease Enterovirus	Infection Inflammation/Immunology
Rupintrivirvr (AG7088), an antiviral agent, is a potent, selective and irreversible inhibitor of *human rhinovirus (HRV) 3C protease. Rupintrivirvr inhibits replication of a panel of 48 different HRV* serotypes in H1-HeLA and MRC-5 cell protection assays, with a mean EC₅₀ of 0.023 μM. Rupintrivirvr shows immune-modulatory effect .

HY-162022

BTA-188	Enterovirus Virus Protease	Infection
BTA-188, a pyridazinyl oxime ether, is an orally active, potent inhibitor of rhinoviruses (HRV) and enterovirus (EV) 71 in vitro. BTA-188 inhibits HRV-2 replication with an IC₅₀ of 0.8 nM and an IC₉₀ of 11 nM. BTA-188 inhibits enterovirus with an IC₅₀ of 82 and an IC₉₀ of 109 nM. BTA-188 is a potential chemotherapeutic agent for infections caused by the viruses in the Picornaviridae .

HY-161357

KR-27370	PI4K	Infection
KR-27370 (compound 7f) is an antiviral agent and selective PI4KIIIβ/PI4KIIIα inhibitor (IC₅₀: 3.1 nM/15.8 nM), against hRV, Ke Saatchivirus and other enteroviruses have inhibitory activity[1].br/ .

HY-N1111

Uncaric acid 6β,19α-Dihydroxyursolic acid	HIV	Infection
Uncaric acid (6β,19α-Dihydroxyursolic acid) (compound 6) is a triterpene that can be found in Eriobotrya japonica. Uncaric acid shows anti HIV-1, HRV 1B, SNV activity .

HY-106774

R-61837	Enterovirus	Infection
R-61837 is a synthetic antirhinoviral compound with significant in vitro activity. R-61837 is 10 times and 57 times more active against human rhinovirus type 9 (HRV-9) than Enviroxime and dichloroflavone (DCF), respectively, and is more active against human rhinovirus type 2 (HRV-2 ) were 5 times and 10 times higher respectively .

HY-163377

AZ5385	Enterovirus EGFR	Infection
AZ5385 is an EGFR-tyrosine kinase inhibitor. AZ5385 is a *HRV-2* virus blocker, with EC₅₀ of 0.35 µM. AZ5385 affects the late stage of viral life cycle .

HY-106161S1

Rupintrivir-d7 AG7088-d₇	Isotope-Labeled Compounds Enterovirus Virus Protease	Infection
Rupintrivir-d7 is a deuterated labeled Rupintrivir . Rupintrivirvr (AG7088), an antiviral agent, is a potent, selective and irreversible inhibitor of *human rhinovirus (HRV) 3C protease. Rupintrivirvr inhibits replication of a panel of 48 different HRV* serotypes in H1-HeLA and MRC-5 cell protection assays, with a mean EC₅₀ of 0.023 μM. Rupintrivirvr shows immune-modulatory effect .

HY-P5843

Citrullinated LL-37 4cit	Enterovirus	Infection
Citrullinated LL-37 3cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 3cit lacks all antiviral activity at 10 μg/mL and retains some activity against *HRV* at 30 μg/mL. Citrullinated LL-37 3cit reduces the immunomodulatory activity of LL-37. Citrullinated LL-37 3cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion .

HY-P5842

Citrullinated LL-37 3cit	Bacterial Influenza Virus	Infection
Citrullinated LL-37 3cit is a host defense peptide (HDP) with broad immunomodulatory and antimicrobial activities. Citrullinated LL-37 3cit exhibits direct antiviral effects against human rhinoviruses (HRV) .

HY-P5837

Citrullinated LL-37 2cit	Interleukin Related Enterovirus	Inflammation/Immunology
Citrullinated LL-37 2cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 2cit reduces LL-37 activity against HRV at 10 μg/mL and reduces the antibacterial effect of LL-37. Citrullinated LL-37 2cit causes a reduction in the levels of IL-8, CCL5, and IL-6 mRNA induced by RV1B. Citrullinated LL-37 2cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion .

HY-E70528

PreScission protease	Biochemical Assay Reagents	Others
PreScission Protease is a recombinant protease that combines human rhinovirus (HRV) type 14 3C protease and a GST-tag. PreScission Protease can specifically recognize the short peptide Leu-Glu-Val-Leu-Phe-Gln-Gly-Pro at 4°C and cleave between Gln and Gly amino acids .

HY-168034

diABZI-4	STING	Infection Inflammation/Immunology
diABZI-4 is an oral active STING agonist with broad-spectrum antiviral activity. diABZI-4 induces the production of pro-inflammatory cytokines and lymphocyte activation by activating STING, thereby inhibiting the replication of influenza A virus (IAV), SARS-CoV-2, and human rhinovirus (HRV), with an EC₅₀ range of 11.8-199 nM .

HY-121527

Amylmetacresol	Enterovirus Influenza Virus Bacterial	Infection Neurological Disease
Amylmetacresol is a phenolic compound with topical antibacterial and antiviral activity. Amylmetacresol works by destroying the protein structure of the virus surface or interfering with the function of the virus lipid membrane. Amylmetacresol inhibits the attachment and replication of respiratory viruses such as human Rhinovirus 1a and influenza virus A, without significant effect on viruses such as *HRV8*. Amylmetacresol is mainly applied topically to the throat to relieve viral sore throats. Amylmetacresol is more active against enveloped viruses than non-enveloped viruses .

HY-117318

PDE12-IN-1	Phosphodiesterase (PDE)	Infection
PDE12-IN-1 is a potent and selective PDE12 inhibitor with a pIC₅₀ value for enzyme inhibition of 9.1. PDE12-IN-1 increases 2′,5′-linked adenylate polymers (2-5A) levels, and the pEC₅₀ value is 7.7. PDE12-IN-1 shows antiviral activity .

HY-N14780

Pochonin D (+)-Pochonin D	HSP Interleukin Related Enterovirus	Infection Inflammation/Immunology Cancer
Pochonin D ((+)-Pochonin D) is an inhibitor of heat shock protein 90 (Hsp90) with antiviral and anti-inflammatory activities. Pochonin D inhibits Hsp90, affecting the homeostasis, folding, and assembly processes of viral proteins, reducing the replication ability of the virus. Pochonin D reduces the infiltration of inflammatory cells and the secretion of inflammatory cytokines such as TNF-α and IL-1β, alleviating the inflammatory response. Pochonin D is promising for research of Human rhinoviruses (HRV) infections and cancers .

HY-N6025

Clemastanin B	Influenza Virus	Infection Inflammation/Immunology
Clemastanin B, a lignin, has potent anti-influenza activities by inhibiting the virus multiplication, prophylaxsis and blocking the virus attachment. Clemastanin B targets viral endocytosis, uncoating or ribonucleoprotein (RNP) export from the nucleus. Clemastanin B has antioxidant and anti-inflammatory activities .

Cat. No.	Product Name	Target	Research Area

HY-P5843

Citrullinated LL-37 4cit	Enterovirus	Infection
Citrullinated LL-37 3cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 3cit lacks all antiviral activity at 10 μg/mL and retains some activity against *HRV* at 30 μg/mL. Citrullinated LL-37 3cit reduces the immunomodulatory activity of LL-37. Citrullinated LL-37 3cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion .

HY-P5842

Citrullinated LL-37 3cit	Bacterial Influenza Virus	Infection
Citrullinated LL-37 3cit is a host defense peptide (HDP) with broad immunomodulatory and antimicrobial activities. Citrullinated LL-37 3cit exhibits direct antiviral effects against human rhinoviruses (HRV) .

HY-P5837

Citrullinated LL-37 2cit	Interleukin Related Enterovirus	Inflammation/Immunology
Citrullinated LL-37 2cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 2cit reduces LL-37 activity against HRV at 10 μg/mL and reduces the antibacterial effect of LL-37. Citrullinated LL-37 2cit causes a reduction in the levels of IL-8, CCL5, and IL-6 mRNA induced by RV1B. Citrullinated LL-37 2cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6025

Clemastanin B	Structural Classification Classification of Application Fields Cruciferae Source classification Lignans Isatis tinctoria L. Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields	Influenza Virus
Clemastanin B, a lignin, has potent anti-influenza activities by inhibiting the virus multiplication, prophylaxsis and blocking the virus attachment. Clemastanin B targets viral endocytosis, uncoating or ribonucleoprotein (RNP) export from the nucleus. Clemastanin B has antioxidant and anti-inflammatory activities .

HY-N1111

Uncaric acid 6β,19α-Dihydroxyursolic acid	Triterpenes Structural Classification Terpenoids Source classification Rosaceae Plants Eriobotrya japonica (Thunb.) Lindl.	HIV
Uncaric acid (6β,19α-Dihydroxyursolic acid) (compound 6) is a triterpene that can be found in Eriobotrya japonica. Uncaric acid shows anti HIV-1, HRV 1B, SNV activity .

HY-N14780

Pochonin D (+)-Pochonin D	Structural Classification Natural Products Microorganisms Source classification	HSP Interleukin Related Enterovirus
Pochonin D ((+)-Pochonin D) is an inhibitor of heat shock protein 90 (Hsp90) with antiviral and anti-inflammatory activities. Pochonin D inhibits Hsp90, affecting the homeostasis, folding, and assembly processes of viral proteins, reducing the replication ability of the virus. Pochonin D reduces the infiltration of inflammatory cells and the secretion of inflammatory cytokines such as TNF-α and IL-1β, alleviating the inflammatory response. Pochonin D is promising for research of Human rhinoviruses (HRV) infections and cancers .

Cat. No.	Product Name	Chemical Structure

HY-106161S1

Rupintrivir-d7
Rupintrivir-d7 is a deuterated labeled Rupintrivir . Rupintrivirvr (AG7088), an antiviral agent, is a potent, selective and irreversible inhibitor of *human rhinovirus (HRV) 3C protease. Rupintrivirvr inhibits replication of a panel of 48 different HRV* serotypes in H1-HeLA and MRC-5 cell protection assays, with a mean EC₅₀ of 0.023 μM. Rupintrivirvr shows immune-modulatory effect .

Rupintrivir-d7

Rupintrivir-d7 is a deuterated labeled Rupintrivir . Rupintrivirvr (AG7088), an antiviral agent, is a potent, selective and irreversible inhibitor of human rhinovirus (HRV) 3C protease. Rupintrivirvr inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and MRC-5 cell protection assays, with a mean EC₅₀ of 0.023 μM. Rupintrivirvr shows immune-modulatory effect .

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