2. Search Result
Search Result
Results for "

HM-1

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

3

Peptides

2

Inhibitory Antibodies

1

Natural
Products

3

Recombinant Proteins

1

Antibodies

1

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99381
    XmAb 5592
    1 Publications Verification

    		 Transmembrane Glycoprotein Cancer
    XmAb 5592 is a humanized, Fc-engineered anti-HM1.24 antibody with enhanced binding to FcγRIIIa and FcγRIIa receptors, augments HM1.24-specific multiple myeloma (MM) cells lysis in vitro via antibody-dependent cellular cytotoxicity (ADCC) and antibody dependent cellular phagocytosis (ADCP) [1].
    XmAb 5592
  • HY-U00302
    CHF5407

    		mAChR Inflammation/Immunology
    CHF5407 is a selective, long-acting and competitive muscarinic M3 receptor antagonist. CHF5407 shows subnanomolar affinities for human muscarinic M1 (hM1), M2 (hM2) and M3 (hM3) receptors. CHF5407 shows a prolonged antibronchospastic activity [1].
    CHF5407
  • HY-N2263
    Skimmin
    1 Publications Verification

    Umbelliferone glucoside

    		 Interleukin Related TGF-β Receptor TNF Receptor Parasite Inflammation/Immunology
    Skimmin (Umbelliferone glucoside) is a major pharmacologically active and orally active molecule present in Hydrangea paniculata, a medical herb used in traditional Chinese medicine as an anti-inflammatory agent. Skimmin has renal protective activity. Skimmin can improve creatinine clearance, and reduce plasma creatinine, and kidney injuries. Skimmin has good anti-amoebic activity against the HM1:IMMS strain of Entamoeba histolytica. Skimmin has anti-cancer and neuroprotective activities. Skimmin reduces cardiac fibrosis as well as decreasing TNF-α, IL-6, IL1β, and TGFβ1 in cardiac tissues. Skimmin can be studied in research for diabetes and diabetes-related diseases [1] .
    Skimmin
  • HY-P99134
    Anti-Mouse GM-CSF Antibody (MP1-22E9)

    		c-Fms Infection Inflammation/Immunology Cancer
    Anti-Mouse GM-CSF Antibody (MP1-22E9) is a rat-derived anti-mouse GM-CSF IgG2a antibody inhibitor. Anti-Mouse GM-CSF Antibody (MP1-22E9) can neutralize GM-CSF. Anti-Mouse GM-CSF Antibody (MP1-22E9) can be used for the researches of cancer, infection inflammation and immunology, such as cholangiocarcinoma and arthritis [1] .
    Anti-Mouse GM-CSF Antibody (MP1-22E9)
  • HY-P5183
    Hm1a

    		Sodium Channel Neurological Disease
    Hm1a is a disulfide-rich spider-venom peptide, and a NaV1.1 activator. Hm1a restores the function of inhibitory interneurons in Dravet syndrome (DS) mouse model [1].
    Hm1a
  • HY-116569
    VU0455691

    		mAChR Cardiovascular Disease
    VU0455691 is a potent, selective orthosteric M1 mAChR antagonist (pIC50=6.64; IC50=0.23 µM for hM1) [1].
    VU0455691
  • HY-P5782
    δ-Theraphotoxin-Hm1a toxin

    		Sodium Channel Neurological Disease
    δ-Theraphotoxin-Hm1a toxin is a selective Nav1.1 activator. δ-Theraphotoxin-Hm1a toxin elicits pain and touch sensitivity. δ-Theraphotoxin-Hm1a toxin can be used for the research of irritable bowel syndrome [1].
    δ-Theraphotoxin-Hm1a toxin
  • HY-P5781
    δ-Theraphotoxin-Hm1b

    		Sodium Channel Neurological Disease
    δ-Theraphotoxin-Hm1b is a 42-amino acid peptide isolated from Togo starburst tarantula (Heteroscodra maculata) venom. δ-Theraphotoxin-Hm1b selectively inhibits inactivation of NaV1.1 but have no effect on NaV1.7 [1].
    δ-Theraphotoxin-Hm1b
  • HY-107656
    PTAC oxalate

    		mAChR Neurological Disease
    PTAC oxalate is a selective muscarinic receptor ligand. PTAC oxalate is an partial agonist of M2 and M4 but antagonist of M1, M3, and M5 (Ki values of 0.2-2.8 nM for hM1-5 in CHO cells). PTAC oxalate alleviates the mechanical allodynia on the neuropathic pain and has antidepression effects [1] .
    PTAC oxalate
  • HY-RS02660
    CHRM1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CHRM1 Human Pre-designed siRNA Set A contains three designed siRNAs for CHRM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CHRM1 Human Pre-designed siRNA Set A
    CHRM1 Human Pre-designed siRNA Set A

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: