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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

HLA-DR Antibody

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) CD47 (1) JNK (1) MHC (2)
By Research Areas:	Cancer (3) Infection (1) Inflammation/Immunology (1)

3

Inhibitors & Agonists

4

Inhibitory Antibodies

6

Antibodies

Targets Recommended: ADC Antibody Antibody-Drug Conjugates (ADCs) CD74 ADC Linker PROTAC-Linker Conjugates for PAC

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*Anti-Monkey/Human MHC class II (HLA-DR) Antibody* (L243)**	MHC Apoptosis	Infection Cancer
Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to monkey/human MHC class II. Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) can inhibits tumor cells proliferation and induce apoptosis. Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) increases cellular reactive oxygen species (ROS) and loss of mitochondrial membrane potential in human endothelial cells. Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) can be used for the researches of cancer and infection, such as lymphoma .

IBI-397 AL008	CD47	Cancer
IBI-397 is a human monoclonal antibody (mAb) targeting SIRPα/CD172a . IBI-397 promotes human monocyte-derived dendritic cell-mediated T cell proliferation and increases the expression of CD86 and HLA-DR. IBI-397 has antitumor activity in the mouse MDA-MB-231 tumor model. IBI-397 can be used in Myeloma research .

1D09C3	MHC Apoptosis JNK	Cancer
1D09C3 is a fully human anti-HLA-DR monoclonal antibody. 1D09C3 induces apoptosis and cell death involving a cascade of events, including ROS generation, JNK activation, mitochondrial membrane depolarization, and AIF release from mitochondria. 1D09C3 shows potent anti-tumor activity and increases overall survival and median survival in JVM-2 cells and GRANTA-519 cells xenograft mice models. 1D09C3 can be used for the researches of cancer, such as chronic lymphocytic leukemia (CLL) ^{[1] ^{^{[2] ^{^{[3] ^.}}}}}

Cat. No.	Product Name	Target	Research Area

*Anti-Monkey/Human MHC class II (HLA-DR) Antibody* (L243)**	MHC Apoptosis	Infection Cancer
Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) is a mouse-derived IgG2a κ type antibody inhibitor, targeting to monkey/human MHC class II. Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) can inhibits tumor cells proliferation and induce apoptosis. Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) increases cellular reactive oxygen species (ROS) and loss of mitochondrial membrane potential in human endothelial cells. Anti-Monkey/Human MHC class II (HLA-DR) Antibody (L243) can be used for the researches of cancer and infection, such as lymphoma .

IMMU-114	Inhibitory Antibodies	Inflammation/Immunology
IMMU-114 is a CHO expressed humanized antibody that targets *HLA-DR*. IMMU-114 is composed of huIgG4SP heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145.1 kDa. The isotype control for IMMU-114 can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).

IBI-397 AL008	CD47	Cancer
IBI-397 is a human monoclonal antibody (mAb) targeting SIRPα/CD172a . IBI-397 promotes human monocyte-derived dendritic cell-mediated T cell proliferation and increases the expression of CD86 and HLA-DR. IBI-397 has antitumor activity in the mouse MDA-MB-231 tumor model. IBI-397 can be used in Myeloma research .

1D09C3	MHC Apoptosis JNK	Cancer
1D09C3 is a fully human anti-HLA-DR monoclonal antibody. 1D09C3 induces apoptosis and cell death involving a cascade of events, including ROS generation, JNK activation, mitochondrial membrane depolarization, and AIF release from mitochondria. 1D09C3 shows potent anti-tumor activity and increases overall survival and median survival in JVM-2 cells and GRANTA-519 cells xenograft mice models. 1D09C3 can be used for the researches of cancer, such as chronic lymphocytic leukemia (CLL) ^{[1] ^{^{[2] ^{^{[3] ^.}}}}}

Cat. No.	Compare	Product Name	Application	Reactivity

	HLA DR Antibody (YA3084) MLRW; HLA-DRA1; MHC class II antigen DRA; HLA class II histocompatibility antigen; DR alpha chain	WB, IHC-P, ICC/IF, FC	Human
	HLA DR Antibody (YA3084) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3084), targeting HLA DR, with a predicted molecular weight of 29 kDa (observed band size: 29 kDa). HLA DR Antibody (YA3084) can be used for WB, IHC-P, ICC/IF, FC experiment in human background.

	CD74 Antibody (YA1282) CD74; DHLAG; HLA class II histocompatibility antigen gamma chain; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; Ii; p33; CD74	IHC-P	Human
	CD74 Antibody (YA1282) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1282), targeting CD74. CD74 Antibody (YA1282) can be used for IHC-P experiment in human background.

	CD74 Antibody (YA5590) CD 74 Antibody; CD74 Antibody; CD74 antigen; invariant polypeptide of major histocompatibility complex; class II antigen-associated; Antibody; CD74 antigen Antibody; CD74 molecule Antibody; CD74 molecule; major histocompatibility complex; class II invariant chain Antibody; CLIP Antibody; DHLAG Antibody; Gamma chain of class II antigens Antibody; HG2A_HUMAN Antibody; HLA class II histocompatibility antigen gamma chain Antibody; HLA DR antigens associated invariant chain Antibody; HLA DR gamma Antibody; HLA-DR antigens-associated invariant chain Antibody; HLA-DR-gamma Antibody; HLADG Antibody; HLADR antigens associated invariant chain Antibody; Ia antigen associated invariant chain Antibody; Ia antigen-associated invariant chain Antibody; Ia associated invariant chain Antibody; Ia gamma Antibody; Ii Antibody; Invariant polypeptide of major histocompatibility complex class II antigen associated Antibody; la-gamma Antibody; Major histocompatibility complex class II invariant chain Antibody; MHC HLA DR gamma chain Antibody; MHC HLA-DR gamma chain Antibody; p33 Antibody; p35 Antibody; Protein 41 Antibody;	IHC-P, WB, ICC/IF, ELISA	Human
	CD74 Antibody (YA5590) is a mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CD74. It can be applicated for IHC-P, WB, ICC/IF, ELISA assays, in the background of human.

	CD74 Antibody (YA4699) HLA class II histocompatibility antigen gamma chain; HLA-DR antigens-associated invariant chain; Ia antigen-associated invariant chain; Ii; p33; CD antigen CD74; CD74 nanobody	ELISA, FC	Human
	CD74 Antibody (YA4699) is a mouse-derived and non-conjugated monoclonal antibody, targeting to CD74. It can be applicated for ELISA, FC assays, in the background of human.

	HLA-DRA Antibody (YA4707) DASS-397D15.1 Antibody; DR alpha chain Antibody; DR alpha chain precursor Antibody; DRA_HUMAN Antibody; DRB1 Antibody; DRB4 Antibody; FLJ51114 Antibody; Histocompatibility antigen HLA DR alpha Antibody; Histocompatibility antigen HLA-DR alpha Antibody; HLA class II histocompatibility antigen Antibody; HLA class II histocompatibility antigen DR alpha chain Antibody; HLA DR1B Antibody; HLA DR3B Antibody; HLA DRA Antibody; HLA DRA1 Antibody; HLA DRB1 Antibody; HLA DRB3 Antibody; HLA DRB4 Antibody; HLA DRB5 Antibody; HLA-DR histocompatibility type Antibody; HLA-DRA Antibody; HLADR4B Antibody; HLADRA1 Antibody; HLADRB Antibody; Major histocompatibility complex class II DR alpha Antibody; Major histocompatibility complex class II DR beta 1 Antibody; Major histocompatibility complex class II DR beta 3 Antibody; Major histocompatibility complex class II DR beta 4 Antibody; Major histocompatibility complex class II DR beta 5 Antibody; MGC117330 Antibody; MHC cell surface glycoprotein Antibody; MHC class II antigen DRA Antibody; MHC II Antibody; MLRW Antibody; OTTHUMP00000029406 Antibody; OTTHUMP00000029407 Antibody; HLA-DRA nanobody	ELISA	Human
	HLA-DRA Antibody (YA4707) is a mouse-derived and non-conjugated monoclonal antibody, targeting to HLA-DRA. It can be applicated for ELISA assays, in the background of human.

	HLA-DRB1 Antibody (YA3614) SS1; DRB1; HLA-DRB; HLA-DR1B	WB, IHC-P, FC, ELISA	Human
	HLA-DRB1 Antibody (YA3614) is a mouse-derived and non-conjugated IgG1 antibody, targeting to HLA-DRB1. It can be applicated for WB, IHC-P, FC, ELISA assays, in the background of human.

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