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Isoforms Recommended: HIPK
Results for "

HIPK2

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

1

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-128439
    BT173

    		DYRK Cancer
    BT173 is a potent homeodomain interacting protein kinase 2 (HIPK2) inhibitor. BT173 binds to HIPK2 and does not inhibit HIPK2 kinase activity but rather, interfered allosterically with the ability of HIPK2 to associate with Smad3. BT173 attenuates renal fibrosis through suppression of the TGF-β1/Smad3 pathway. BT173 can be studied in research for kidney diseases such as renal fibrosis .
    BT173
  • HY-U00439A
    Protein kinase inhibitor 1 hydrochloride
    4 Publications Verification

    		 DYRK Cancer
    Protein kinase inhibitor 1 hydrochloride is a potent HIPK2 inhibitor, with IC50s of 136 and 74 nM for HIPK1 and HIPK2, and a Kd of 9.5 nM for HIPK2.
    Protein kinase inhibitor 1 hydrochloride
  • HY-100464
    tBID
    5 Publications Verification

    		 DYRK Cancer
    tBID is a selective inhibitor of homeodomain-interacting protein kinase 2 (HIPK2) with an IC50 of 0.33 μM.
    tBID
  • HY-135906
    CK2/ERK8-IN-1
    2 Publications Verification

    		 Casein Kinase ERK Pim DYRK Apoptosis Cancer
    CK2/ERK8-IN-1 is a dual casein kinase 2 (CK2) (Ki of 0.25 µM) and ERK8 (MAPK15, ERK7) inhibitor with IC50s of 0.50 μM. CK2/ERK8-IN-1 also binds to PIM1, HIPK2 (homeodomain-interacting protein kinase 2), and DYRK1A with Kis of 8.65 µM, 15.25 µM, and 11.9 µM, respectively. CK2/ERK8-IN-1 has pro-apoptotic efficacy .
    CK2/ERK8-IN-1
  • HY-E70830
    HIPK2 Recombinant Human Active Protein Kinase

    		DYRK Cancer
    Homeodomain interacting protein kinase 2 (HIPK2) is an evolutionary conserved serine/threonine kinase that regulates gene expression by phosphorylation of transcription factors and accessory components of the transcription machinery. HIPK2 is activated in response to DNA-damaging agents or morphogenic signals. HIPK2 Recombinant Human Active Protein Kinase is a recombinant HIPK2 protein that can be used to study HIPK2-related functions .
    HIPK2 Recombinant Human Active Protein Kinase
  • HY-RS23297
    Hipk2 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) DYRK Others

    Hipk2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Hipk2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Components

    Hipk2 siRNA-1: 5 nmol (HPLC)

    Hipk2 siRNA-2: 5 nmol (HPLC)

    Hipk2 siRNA-3: 5 nmol (HPLC)

    siRNA Negative Control: 5 nmol (HPLC)

    FAM-labeled siRNA Negative Control: 5 nmol (HPLC)

    GAPDH siRNA Positive Control: 5 nmol (HPLC)
    Hipk2 Rat Pre-designed siRNA Set A
    Hipk2 Rat Pre-designed siRNA Set A
  • HY-RS06182
    HIPK2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    HIPK2 Human Pre-designed siRNA Set A contains three designed siRNAs for HIPK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    HIPK2 Human Pre-designed siRNA Set A
    HIPK2 Human Pre-designed siRNA Set A
  • HY-RS16856
    Hipk2 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Hipk2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hipk2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Hipk2 Mouse Pre-designed siRNA Set A
    Hipk2 Mouse Pre-designed siRNA Set A
  • HY-U00439
    Protein kinase inhibitor 1

    		DYRK Cancer
    Protein kinase inhibitor 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.
    Protein kinase inhibitor 1
  • HY-177416
    MU1787

    		DYRK Others
    MU1787 (Compound 22h) is a Homeodomain interacting protein kinase (HIPK) inhibitor with IC50s of 285, 123 and 283 nM for HIPK1, HIPK2 and HIPK3, respectively. HIPK have distinct or contradictory effects on cell proliferation and tissue growth .
    MU1787

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