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Results for "

HDL (human)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apolipoprotein (1) Biochemical Assay Reagents (1) NO Synthase (1) PPAR (2)
By Research Areas:	Cardiovascular Disease (1) Metabolic Disease (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-50665

LY518674 LY-674	PPAR	Metabolic Disease
LY518674 is a potent, selective PPARα agonist, with an EC₅₀ of 42 nM for human PPARα. LY518674 reduces triglycerides in and increased HDL-C and is used for the treatment of atherosclerosis .

HY-124187

Pinolenic acid ethyl ester Ethyl pinolenate	Biochemical Assay Reagents	Others
Pinolenic acid is a polyunsaturated fatty acid found in the seed oils of red pine (Pinus orientalis) and maritime pine (Pinus pinaster). Both oils were found to have lipid-lowering properties. A diet containing marine pine nut oil (MPSO) reduces HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to reduce cholesterol efflux in vitro. Korean pine nut oil supplements may help obesity by reducing appetite. People who take this oil experience an increase in the satiety hormones CCK and GLP-1 and a decrease in appetite. The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not metabolized to arachidonic acid and can reduce the level of arachidonic acid in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%. Pinolenic acid ethyl ester is a neutral, more lipophilic form of the free acid.

HY-NP203

*High density lipoprotein (human)* HDL (human)	Apolipoprotein NO Synthase	Cardiovascular Disease
High density lipoprotein (HDL) (human) is a functional lipoprotein that binds to receptors such as scavenger receptor B1 (SR-B1), ABCA1 and ABCG1. High density lipoprotein (human) clears excess cholesterol from peripheral tissues through reverse cholesterol transport (RCT) and transports it to the liver for metabolism, while activating endothelial nitric oxide synthase (eNOS) to produce nitric oxide (NO), exerting antioxidant, anti-inflammatory, and vascular endothelial protective activities. High density lipoprotein (human) is promising for research of cardiovascular diseases, such as atherosclerosis .

HY-115357

BMS711939	PPAR	Metabolic Disease
BMS711939 is a selective agonist for peroxisome proliferator-activated receptor α (PPAR α), with EC₅₀ of 4 nM and 4.5 μM, for human PPARα and human PPARγ. BMS711939 exhibits good pharmacokinetic characters in rats models. BMS711939 increases HDL cholesterol, reduces LDL cholesterol and triglycerides .

Cat. No.	Product Name	Type

HY-124187

Pinolenic acid ethyl ester Ethyl pinolenate	Drug Delivery
Pinolenic acid is a polyunsaturated fatty acid found in the seed oils of red pine (Pinus orientalis) and maritime pine (Pinus pinaster). Both oils were found to have lipid-lowering properties. A diet containing marine pine nut oil (MPSO) reduces HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to reduce cholesterol efflux in vitro. Korean pine nut oil supplements may help obesity by reducing appetite. People who take this oil experience an increase in the satiety hormones CCK and GLP-1 and a decrease in appetite. The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not metabolized to arachidonic acid and can reduce the level of arachidonic acid in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%. Pinolenic acid ethyl ester is a neutral, more lipophilic form of the free acid.

Pinolenic acid ethyl ester

Ethyl pinolenate

Drug Delivery

Pinolenic acid is a polyunsaturated fatty acid found in the seed oils of red pine (Pinus orientalis) and maritime pine (Pinus pinaster). Both oils were found to have lipid-lowering properties. A diet containing marine pine nut oil (MPSO) reduces HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to reduce cholesterol efflux in vitro. Korean pine nut oil supplements may help obesity by reducing appetite. People who take this oil experience an increase in the satiety hormones CCK and GLP-1 and a decrease in appetite. The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not metabolized to arachidonic acid and can reduce the level of arachidonic acid in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%. Pinolenic acid ethyl ester is a neutral, more lipophilic form of the free acid.

HY-NP203

*High density lipoprotein (human)* HDL (human)	Native Proteins
High density lipoprotein (HDL) (human) is a functional lipoprotein that binds to receptors such as scavenger receptor B1 (SR-B1), ABCA1 and ABCG1. High density lipoprotein (human) clears excess cholesterol from peripheral tissues through reverse cholesterol transport (RCT) and transports it to the liver for metabolism, while activating endothelial nitric oxide synthase (eNOS) to produce nitric oxide (NO), exerting antioxidant, anti-inflammatory, and vascular endothelial protective activities. High density lipoprotein (human) is promising for research of cardiovascular diseases, such as atherosclerosis .

High density lipoprotein (human)

HDL (human)

Native Proteins

High density lipoprotein (HDL) (human) is a functional lipoprotein that binds to receptors such as scavenger receptor B1 (SR-B1), ABCA1 and ABCG1. High density lipoprotein (human) clears excess cholesterol from peripheral tissues through reverse cholesterol transport (RCT) and transports it to the liver for metabolism, while activating endothelial nitric oxide synthase (eNOS) to produce nitric oxide (NO), exerting antioxidant, anti-inflammatory, and vascular endothelial protective activities. High density lipoprotein (human) is promising for research of cardiovascular diseases, such as atherosclerosis .

Species:	Human (2)
Tag:	His (1) SUMO (1) Fc (1)
Source:	HEK293 (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P70873

	*GPIHBP1 Protein, Human* (HEK293, Fc)** glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein1; GPI anchored high density lipoprotein binding protein 1; GPI-Anchored HDL-Binding Protein 1; GPIHBP1; GPI-HBP1; GPI-HBP1LOC338328; HBP1; High density lipoprotein-binding protein 1; H	Human	HEK293
	The GPIHBP1 protein mediates lipid metabolism by transporting lipoprotein lipase LPL, anchoring it in capillaries, and preventing loss of activity. It has a crucial role in chylomicron lipolysis, triglyceride metabolism, and overall lipid homeostasis. GPIHBP1 Protein, Human (HEK293, Fc) is the recombinant human-derived GPIHBP1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P72237

	*HSD11B1 Protein, Human* (His-SUMO)** 11 beta HSD 1; 11 beta HSD1 ; 11 beta hydroxysteroid dehydrogenase 1; 11 DH ; 11-beta hydroxysteroid dehydrogenase; type 1; 11-beta-HSD1; 11-DH; 11DH ; Corticosteroid 11 beta dehydrogenase isozyme 1; Corticosteroid 11-beta-dehydrogenase isozyme 1; CORTRD2; DHI1_HUMAN; HDL; HSD 11; HSD11; HSD11B; HSD11B1; HSD11L; member 1	Human	E. coli
	The proteins encoded by ED genes are involved in a variety of physiological processes. HSD11B1 Protein, Human (His-SUMO) is the recombinant human-derived HSD11B1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

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